A Three-Year Retrospective Study on Survival of Ceramic-Veneered Zirconia (Y-TZP) Fixed Dental Prostheses Performed in Private Practices

Objectives. The aim of this retrospective study was to evaluate the three-year clinical outcome for ceramic-veneered zirconia fixed dental prostheses (FDPs). Methods. All patients who were treated with ceramic-veneered zirconia FDPs, in three private practices in Sweden, during the period June 2003 to April 2007 were included. Case records from 151 patients, treated with a total of 184 zirconia FDPs (692 units), were analysed for clinical data. All complications noted in the charts were registered and compared to definitions for success and survival and statistical analysis was performed using the Kaplan-Meier method and a Cox regression model. Results. In total, 32 FDPs in 31 patients experienced some type of complication (17.4% of FDPs, 20.5% of patients). Core fractures occurred in two (1.1%) FDPs. Two (1.1%) FDPs or 0.6% of units showed adhesive veneer fractures. Cohesive veneer fractures occurred in 10 (5.4%) FDPs (1.6% of units). The three-year cumulative success and survival rates (CSR) were 82.3% and 95.2%, respectively. Conclusions. Ceramic-veneered zirconia is a promising alternative to metal-ceramic FDPs, even in the posterior area. However, the higher survival rate of metal-ceramic FDPs should be noted and both dentists and patients must be aware of the risks of complications.

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Ceramic Defects in Metal-Ceramic Fixed Dental Prostheses Made from Co-Cr and Au-Pt Alloys: A Retrospective Study

The International Journal of Prosthodontics ◽

10.11607/ijp.4234 ◽

2015 ◽

Vol 28 (5) ◽

pp. 487-489 ◽

Cited By ~ 2

Author(s):

Aikaterini Mikeli ◽

Klaus Boening ◽

Benjamin Lißke

Keyword(s):

Retrospective Study ◽

Dental Prostheses ◽

Metal Ceramic ◽

Fixed Dental Prostheses ◽

Pt Alloys

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Two-Year Longevity of Posterior Zirconia Multi-Unit Fixed Dental Prostheses with Monolithic Occlusal Surface

Applied Sciences ◽

10.3390/app11104449 ◽

2021 ◽

Vol 11 (10) ◽

pp. 4449

Author(s):

Elisabeth Pahncke ◽

Sebastian Hahnel ◽

Oliver Schierz ◽

Michael Benno Schmidt ◽

Anne Schmutzler ◽

...

Keyword(s):

Clinical Trial ◽

Clinical Performance ◽

Short Term ◽

Recall Interval ◽

Dental Prostheses ◽

Kaplan Meier ◽

Occlusal Surfaces ◽

Fixed Dental Prostheses ◽

Posterior Area

In this prospective clinical trial we observed the 2-year clinical performance of posterior tooth-supported multi-unit fixed dental prostheses (FDP) fabricated from zirconia with monolithic occlusal surfaces. Fifty multi-unit FDPs were inserted in 50 patients. After two years of clinical service, 43 restorations were reexamined as one patient had died and six patients were not available for recall. Two biological (root canal treatment: 12 and 14 months) and one technical (debonding: 12 months) complications occurred. According to the Kaplan–Meier analysis, the success rate was 93.7%, and the survival rate was 100%. The six patients who were not available for regular 2-year follow-up were examined after the official 2-year recall interval, and none of the FDPs presented complications or failures. Within the limitations of the current study, the use of multi-unit FDPs with monolithic occlusal surfaces fabricated from zirconia can be recommended for short-term use in the posterior area.

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Survival Rate of 1008 Short Dental Implants with 21 Months of Average Follow-Up: A Retrospective Study

Journal of Clinical Medicine ◽

10.3390/jcm9123943 ◽

2020 ◽

Vol 9 (12) ◽

pp. 3943

Author(s):

João Caramês ◽

Ana Catarina Pinto ◽

Gonçalo Caramês ◽

Helena Francisco ◽

Joana Fialho ◽

...

Keyword(s):

Retrospective Study ◽

Survival Rate ◽

Dental Implants ◽

Cox Regression ◽

Survival Rates ◽

High Survival ◽

Implant Survival ◽

Posterior Maxilla ◽

Clinical Records

This retrospective study evaluated the survival rate of short, sandblasted acid-etched surfaced implants with 6 and 8 mm lengths with at least 120 days of follow-up. Data concerning patient, implant and surgery characteristics were retrieved from clinical records. Sandblasted and acid-etched (SLA)-surfaced tissue-level 6 mm (TL6) or 8 mm (TL8) implants or bone-level tapered 8 mm (BLT8) implants were used. Absolute and relative frequency distributions were calculated for qualitative variables and mean values and standard deviations for quantitative variables. A Cox regression model was performed to verify whether type, length and/or width influence the implant survival. The cumulative implant survival rate was assessed by time-to-event analyses (Kaplan–Meier estimator). In all, 513 patients with a mean age of 58.00 ± 12.44 years received 1008 dental implants with a mean follow-up of 21.57 ± 10.77 months. Most implants (78.17%) presented a 4.1 mm diameter, and the most frequent indication was a partially edentulous arch (44.15%). The most frequent locations were the posterior mandible (53.97%) and the posterior maxilla (31.55%). No significant differences were found in survival rates between groups of type, length and width of implant with the cumulative rate being 97.7% ± 0.5%. Within the limitations of this study, the evaluated short implants are a predictable option with high survival rates during the follow-up without statistical differences between the appraised types, lengths and widths.

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A 5-Year Retrospective Study of Cobalt-Chromium–Based Fixed Dental Prostheses

The International Journal of Prosthodontics ◽

10.11607/ijp.3024 ◽

2013 ◽

Vol 26 (4) ◽

pp. 343-349 ◽

Cited By ~ 10

Author(s):

Per Svanborg ◽

Lena Längström ◽

Ritva Moisio Lundh ◽

Göran Bjerkstig ◽

Anders Örtorp

Keyword(s):

Retrospective Study ◽

Cobalt Chromium ◽

Dental Prostheses ◽

Fixed Dental Prostheses

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A retrospective study of fixed dental prostheses without regular maintenance

Journal of Prosthodontic Research ◽

10.1016/j.jpor.2010.04.003 ◽

2010 ◽

Vol 54 (4) ◽

pp. 173-178 ◽

Cited By ~ 10

Author(s):

Hiroyo Ikai ◽

Taro Kanno ◽

Kohei Kimura ◽

Keiichi Sasaki

Keyword(s):

Retrospective Study ◽

Dental Prostheses ◽

Fixed Dental Prostheses

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The prognosis of hepatoid adenocarcinoma of the stomach: a propensity score-based analysis

10.21203/rs.3.rs-19206/v2 ◽

2020 ◽

Author(s):

Kai Zhou ◽

Anqiang Wang ◽

Sheng Ao ◽

Jiahui Chen ◽

Ke Ji ◽

...

Keyword(s):

Propensity Score ◽

Cox Regression ◽

Radical Surgery ◽

Survival Rates ◽

Cancer Type ◽

Radical Gastrectomy ◽

Hepatoid Adenocarcinoma ◽

Kaplan Meier ◽

Significant Difference ◽

Propensity Matching

Abstract Background : To investigate whether there is a distinct difference in prognosis between hepatoid adenocarcinoma of the stomach ( HAS) and non-hepatoid adenocarcinoma of the stomach (non-HAS) and whether HAS can benefit from radical surgery. Methods : We retrospectively reviewed 722 patients with non-HAS and 75 patients with HAS who underwent radical gastrectomy between 3 November 2009 and 17 December 2018. Propensity score matching (PSM) analysis was used to eliminate the bias among the patients in our study. The relationships between gastric cancer type and overall survival (OS) were evaluated by the Kaplan-Meier method and Cox regression. Results : Our data demonstrate that there was no statistically significant difference in the OS between HAS and non-HAS {K-M, P=log rank (Mantel-Cox), (before PSM P=0.397); (1:1 PSM P=0.345); (1:2 PSM P=0.195)}. Moreover, there were no significant differences in the 1-, 2-, or 3-year survival rates between patients with non-HAS and patients with HAS (before propensity matching, after 1:1 propensity matching, and after 1:2 propensity matching). Conclusion : HAS was generally considered to be an aggressive gastric neoplasm, but its prognosis may not be as unsatisfactory as previously believed.

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Identification and Analysis of Three Hub Prognostic Genes Related to Osteosarcoma Metastasis

Journal of Oncology ◽

10.1155/2021/6646459 ◽

2021 ◽

Vol 2021 ◽

pp. 1-16

Author(s):

Jianye Tan ◽

Haofeng Liang ◽

Bingsheng Yang ◽

Shuang Zhu ◽

Guofeng Wu ◽

...

Keyword(s):

Regression Analysis ◽

Cox Regression ◽

Survival Rates ◽

Prognostic Biomarkers ◽

Messenger Rnas ◽

Hub Genes ◽

Cox Regression Analysis ◽

Expression Levels ◽

Kaplan Meier ◽

Before And After

Osteosarcoma (OS) often occurs in children and often undergoes metastasis, resulting in lower survival rates. Information on the complexity and pathogenic mechanism of OS is limited, and thus, the development of treatments involving alternative molecular and genetic targets is hampered. We categorized transcriptome data into metastasis and nonmetastasis groups, and 400 differential RNAs (230 messenger RNAs (mRNAs) and 170 long noncoding RNAs (lncRNAs)) were obtained by the edgeR package. Prognostic genes were identified by performing univariate Cox regression analysis and the Kaplan–Meier (KM) survival analysis. We then examined the correlation between the expression level of prognostic lncRNAs and mRNAs. Furthermore, microRNAs (miRNAs) corresponding to the coexpression of lncRNA-mRNA was predicted, which was used to construct a competitive endogenous RNA (ceRNA) regulatory network. Finally, multivariate Cox proportional risk regression analysis was used to identify hub prognostic genes. Three hub prognostic genes (ABCG8, LOXL4, and PDE1B) were identified as potential prognostic biomarkers and therapeutic targets for OS. Furthermore, transcriptions factors (TFs) (DBP, ESX1, FOS, FOXI1, MEF2C, NFE2, and OTX2) and lncRNAs (RP11-357H14.16, RP11-284N8.3, and RP11-629G13.1) that were able to affect the expression levels of genes before and after transcription were found to regulate the prognostic hub genes. In addition, we identified drugs related to the prognostic hub genes, which may have potential clinical applications. Immunohistochemistry (IHC) and quantitative real-time polymerase chain reaction (qRT-PCR) confirmed that the expression levels of ABCG8, LOXL4, and PDE1B coincided with the results of bioinformatics analysis. Moreover, the relationship between the hub prognostic gene expression and patient prognosis was also validated. Our study elucidated the roles of three novel prognostic biomarkers in the pathogenesis of OS as well as presenting a potential clinical treatment for OS.

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Impact of nephron sparing surgery on survival in upper urinary tract urothelial carcinoma patients stratified by tumor characteristics

10.21203/rs.3.rs-20146/v2 ◽

2020 ◽

Author(s):

Liang Jin ◽

Ting-shuai Zhai ◽

Zhen Zhou ◽

Xiang Liu ◽

Jia-xin Zhang ◽

...

Keyword(s):

Urinary Tract ◽

Urothelial Carcinoma ◽

Cox Regression ◽

Survival Rates ◽

Upper Urinary Tract ◽

Regression Analyses ◽

Ajcc Stage ◽

Kaplan Meier ◽

Nephron Sparing ◽

Urinary Tract Urothelial Carcinoma

Abstract Background: We aimed to evaluate the impact of nephron sparing surgery (NSS) on survival in upper urinary tract urothelial carcinoma (UTUC) patients stratified by tumor grade and stage compared to radical nephroureterectomy (RNU) or no surgery. Methods: Overall, 10319 UTUC patients between 2004 and 2015 were extracted from the SEER database. Patients were divided into no surgery group, NSS group and RNU group. Kaplan-Meier plots illustrated survival rates according to surgical method. Multivariable Cox regression analyses assessed the effect of different surgical methods on survival rates. Result: Among the 10319 UTUC patients. Kaplan-Meier plots showed that NSS was associated with a higher overall survival (OS) and cancer-specific survival (CSS) in grade Ⅲ and Ⅳ and AJCC stage Ⅳ patients (all p <0.05). In multivariable Cox regression analyses, NSS was prone to a higher OS or CSS in grade Ⅲ ( p > 0.05). Moreover, NSS predisposed to a higher OS only in AJCC stage Ⅳ ( p <0.05). Conclusion: The beneficial effect of NSS was evident in grade Ⅲ or AJCC stage Ⅳ. NSS can be considered in grade Ⅲ or stage Ⅳ, for other grades or stages remains to be seen, both of which will be verified by further prospective research.

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