scholarly journals Biotransformation of Geniposide into Genipin by ImmobilizedTrichoderma reeseiand Conformational Study of Genipin

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Yishun Yang ◽  
Yue Ding ◽  
Tong Zhang
Keyword(s):  
Aspergillus Niger ◽  
Sodium Alginate ◽  
Trichoderma Reesei ◽  
Nmr Spectra ◽  
Trichoderma Viride ◽  
Conformational Study ◽  
H Nmr ◽  
Promising Solution ◽  
Series Of Experiments ◽  
Fermentation Broths

Trichoderma reeseiQM9414,Trichoderma viride3.316,Aspergillus nigerM85, andAspergillus nigerM92 were screened for hydrolyzing geniposide into genipin.T. reeseiwas selected according to theβ-glucosidase activity of the fermentation broths using geniposide as a substrate.T. reeseiwas immobilized by embedding method using sodium alginate as the carrier. Geniposide was hydrolyzed by immobilizedT. reeseiat 28°C (200 rpm) for 34 h, and the yield of genipin was 89%. The product was purified and identified by UV, IR, EIMS, and1H-NMR. Since there were two sets of signals in1H-NMR spectra, a series of experiments were performed and verified that the existence of two conformations was the main reason. Generally, biotransformation of geniposide into genipin by immobilizedT. reeseiprovides a promising solution to the genipin production.

A simple 1H nmr conformational study of some heterocyclic azomethines

1981 ◽  
Vol 59 (8) ◽  
pp. 1205-1207 ◽  
Author(s):  
Francesco A. Bottino ◽  
Maria L. Longo ◽  
Domenico Sciotto ◽  
Michele Torre
Keyword(s):  
Hydrogen Bond ◽  
Chemical Shift ◽  
Intramolecular Hydrogen Bond ◽  
Nmr Spectra ◽  
Variable Temperature ◽  
Rotational Isomerism ◽  
Conformational Study ◽  
Pyrrole Derivatives ◽  
H Nmr ◽  
Intramolecular Hydrogen

The variable temperature 60 MHz 1H nmr spectra of some heterocyclic azomethines exclude the presence of rotational isomerism. Chemical shift values and stereospecific long-range couplings are used to establish that s-trans is the existing conformation. In the case of the pyrrole derivatives a chelated s-trans rotamer is indicated, depending on the presence of an intramolecular hydrogen bond.

Conformational analysis of acyclic compounds with oxygen–sulphur interactions. Part VI. Some 1-thioderivatives of 2-propanol and its acetates

1979 ◽  
Vol 57 (18) ◽  
pp. 2426-2433 ◽  
Author(s):  
Felipe Alcudia ◽  
José L. García Ruano ◽  
Jesús Rodríguez ◽  
Félix Sánchez
Keyword(s):  
Conformational Analysis ◽  
Nmr Spectra ◽  
Coupling Constants ◽  
Conformational Study ◽  
Conformational Preference ◽  
Methyl Group ◽  
Opposite Charge ◽  
H Nmr ◽  
Vicinal Coupling Constants

A conformational study of 1-X-2-propanol (X = SH, SMe, SOMe, SO2Me, +SMe2) and their O-acetyl derivatives (X = SMe, SOMe, SO2Me, and +SMe2) is reported. From the relative values of the vicinal coupling constants in 1H nmr spectra it has been possible to establish the conformational preference. When a density of opposite charge is supported by heteratoms, polar factors determined a great predominance of that conformation in which the sulphur function has an anti-relationship with respect to the methyl group. In thiol and thioethers the conformational preference is not so marked.

Conformational study of blocked pentofuranoses and their 1,5-anhydro derivatives by 1H NMR spectroscopy

1984 ◽  
Vol 49 (1) ◽  
pp. 235-243
Author(s):  
Jaroslav Zajíček ◽  
Miloš Buděšínský ◽  
Jiří Farkaš
Keyword(s):  
Spectral Analysis ◽  
Nmr Spectroscopy ◽  
Quantum Chemical Calculations ◽  
1H Nmr ◽  
Quantum Chemical ◽  
1H Nmr Spectroscopy ◽  
Nmr Spectra ◽  
Conformational Study ◽  
H Nmr

Preferred conformations of the furanose ring and conformer population about the C(5)-C(4) bond in a series of benzoylated pentofuranosyl cyanides have been determined from their 1H NMR spectra. For the 1,5-anhydropentofuranose derivatives the results of the 1H NMR spectral analysis have been compared with the quantum chemical calculations.

Conformational structure of ethylene glycol dibenzoate. Vibrational and NMR spectra

1981 ◽  
Vol 46 (8) ◽  
pp. 1913-1929 ◽  
Author(s):  
Bohdan Schneider ◽  
Pavel Sedláček ◽  
Jan Štokr ◽  
Danica Doskočilová ◽  
Jan Lövy
Keyword(s):  
Ethylene Glycol ◽  
Vibrational Spectra ◽  
Nmr Spectra ◽  
Coupling Constants ◽  
Conformational Structure ◽  
Infrared And Raman Spectra ◽  
H Nmr ◽  
Liquid States ◽  
Crystalline Forms ◽  
C Nmr

It was found that three crystalline forms of ethylene glycol dibenzoate can be prepared. Infrared and Raman spectra of these three forms, as well as of the glassy and liquid states, were measured. From 3JHH coupling constants obtained by analysis of the 13C satellite band of the -CH2- group in 1H NMR spectra, and from the 3JCH coupling constants of the -CO.O.CH2- fragment obtained by analysis of the carbonyl band in 13C NMR spectra it was found that in the liquid state the -CH2-CH2- group exists predominantly in the gauche conformational structure, and the bonds C-O-C-C assume predominantly a trans orientation. The results of the analysis of NMR and vibrational spectra were used for the structural interpretation of conformationally sensitive bands in vibrational spectra of ethylene glycol dibenzoate.

Preparation and absolute configuration at C(20) of 21-nor-5α-chol-22-en-24→20-olide derivatives

1981 ◽  
Vol 46 (4) ◽  
pp. 917-925 ◽  
Author(s):  
Vladimír Pouzar ◽  
Miroslav Havel
Keyword(s):  
Absolute Configuration ◽  
Nmr Spectra ◽  
Lithium Salt ◽  
H Nmr ◽  
Chemical Correlation ◽  
Unsaturated Lactones

Reaction of the aldehyde I with the lithium salt of 1-(2-tetrahydropyranyloxy)-2-propyne yielded the compounds II and IV. From the compound II the lactone XII was prepared via the intermediates III and X, the lactone XVIII was prepared from the substance IV via the intermediates V and XVI. The unsaturated lactones XII and XVIII were also prepared by sulfenylation and dehydrosulfenylation of the saturated lactones XIII and XIX. Based on chemical correlation and 1H-NMR spectra analyses of the compounds II and IV, the lactone XII was assigned the 20R-configuration whereas the lactone XVIII was allotted the 20S-configuration.

New type of addition to 5-substituted 4-arylidene-2-(4,5-dihydrofurfurylidene)-N,N-dimethyliminium bisperchlorates. Preparation of 4-substituted 5-(N,N-dimethylamino)-2-furancarbaldehydes

1986 ◽  
Vol 51 (3) ◽  
pp. 573-580 ◽  
Author(s):  
Tibor Gracza ◽  
Zdeněk Arnold ◽  
Jaroslav Kováč
Keyword(s):  
Nmr Spectra ◽  
Addition Reaction ◽  
H Nmr ◽  
Organic Bases ◽  
New Type

4-Arilidene-5-(N,N-dimethyliminium)-2-(4,5-dihydrofurfurylidene)-N,N-dimethyliminium bisperchlorate I undergoes a 1,4-addition reaction with organic bases under re-formation of the furan nucleus; this behaviour has been utilized in the preparation of new 4-substituted 5-(N,N-dimethylamino)-2-furancarbaldehydes II, III. The structure of the prepared compounds has been confirmed by 13C and 1H NMR spectra.

Preparation, properties and structure of some intermediate nido- and arachno-monocarbaboranes

1981 ◽  
Vol 46 (10) ◽  
pp. 2345-2353 ◽  
Author(s):  
Karel Baše ◽  
Bohumil Štíbr ◽  
Jiří Dolanský ◽  
Josef Duben
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Nmr Spectra ◽  
Liquid Ammonia ◽  
X Ray Diffraction ◽  
X Ray ◽  
H Nmr ◽  
Starting Compound

The 6-N(CH3)3-6-CB9H11 carbaborane reacts with sodium in liquid ammonia with the formation of 6-CB9H12- which was used as a starting compound for preparing the 4-CB8H14, 9-L-6-CB9H13 (L = (CH3)2S, CH3CN and P(C6H5)3), 1-(η5-C5H5)-1,2-FeCB9H10-, and 2,3-(η5-C5H5)2-2,31-Co2CB9H10- carboranes. The 4-CB8H14 compound was dehydrogenated at 623 K to give 4-(7)-CB8H12 carborane. Base degradation of 6-N(CH3)3-6-CB9H11 in methanol resulted in the formation of 3,4-μ-N(CH3)3CH-B5H10. The structure of all compounds was proposed on the basis of their 11B and 1H NMR spectra and X-ray diffraction was used in the case of the transition metal complexes.

Conformational study on ribonucleoside O-phosphonylmethyl derivatives by 1H NMR spectroscopy

1985 ◽  
Vol 50 (8) ◽  
pp. 1899-1905 ◽  
Author(s):  
Milena Masojídková ◽  
Jaroslav Zajíček ◽  
Miloš Buděšínský ◽  
Ivan Rosenberg ◽  
Antonín Holý
Keyword(s):  
Nmr Spectroscopy ◽  
1H Nmr ◽  
1H Nmr Spectroscopy ◽  
Conformational Study ◽  
H Nmr ◽  
Conformational Properties

Conformational properties of ribonucleoside 5'-O-phosphonylmethyl derivatives have been determined by 1H NMR spectroscopy and compared with those of natural nucleosides and 5'-nucleotides.

The preparation of 3-amino-3-deoxy-1,2-O-isopropylidene-α-L-erythrofuranose, 3-amino-3-deoxy-1,2-O-isopropylidene-β-D-threofuranose and their derivatives

1980 ◽  
Vol 45 (12) ◽  
pp. 3378-3390 ◽  
Author(s):  
Jiří Jarý ◽  
Milena Masojídková ◽  
Ivan Kozák ◽  
Miroslav Marek ◽  
Jan Staněk
Keyword(s):  
Nucleophilic Substitution ◽  
Sodium Azide ◽  
Sodium Benzoate ◽  
Nmr Spectra ◽  
Subsequent Reduction ◽  
H Nmr ◽  
Amino Derivatives

The title amino derivatives VI and XIV were prepared by nucleophilic substitution of p-toluenesulfonyl derivatives II and XVII with sodium azide or hydrazine and subsequent reduction. Nucleophilic substitution of compounds II and XVII with sodium benzoate was also investigated. The 1H NMR spectra of the substances prepared are discussed.

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