scholarly journals Changes of Subfoveal Choroidal Thickness after Cataract Surgery: A Meta-Analysis

2018 ◽  
Vol 2018 ◽  
pp. 1-16 ◽  
Author(s):  
Shaoxue Zeng ◽  
Chen Liang ◽  
Yueqing He ◽  
Yingying Chen ◽  
Qing Zhao ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Choroidal Thickness ◽  
Meta Analysis ◽  
Enhanced Depth Imaging ◽  
Diabetic Mellitus ◽  
Depth Imaging ◽  
Before And After ◽  
Imaging Optical Coherence Tomography ◽  
Inflammatory Drugs ◽  
Thickness Measurements

Purpose. To investigate the effect of cataract surgery on subfoveal choroid thickness (SFCT) using enhanced-depth imaging optical coherence tomography (EDI-OCT). Materials and Methods. Relevant publications were searched systematically through various databases from inception to March 2018. The unit of choroidal thickness measurements is micrometers. Studies comparing SFCT before and after cataract surgery were retrieved. All qualified articles were analyzed using RevMan 5.3. Results. A total of 13 studies with 802 eyes from 646 patients were identified for inclusion. There was a significant increase of SFCT at 1 week (MD = 6.62, 95% CI: 1.20–12.05, P=0.02, I2 = 0%), 1 month (MD = 8.30, 95% CI: 3.20–13.39, P=0.001, I2 = 0%), and 3 months (MD = 8.28, 95% CI: 1.84–14.73, P=0.01, I2 = 0%) after cataract surgery. In subgroup analysis, SFCT in Asians and patients without nonsteroidal anti-inflammatory drugs (NSAIDs) in postoperative medication was significantly thicker (P<0.05). No statistically significant increase of SFCT was found in diabetic mellitus (DM) patients for 1 day (P=0.89), 1 week (P=0.59), 1 month (P=0.52), and 3 months (P=0.42) after cataract surgery. Conclusions. This meta-analysis suggested that SFCT increased since 1 week after the cataract surgery and the increase lasted for at least 3 months. Asians and patients without NSAIDs in postoperative medication were more likely to have a thicker SFCT after cataract surgery, whereas DM patients were less likely to increase in SFCT.

scholarly journals A longitudinal study of choroidal changes following cataract surgery in patients with diabetes

2019 ◽  
Vol 16 (4) ◽  
pp. 369-377 ◽  
Author(s):  
Vivien Cherng-Hui Yip ◽  
Augustinus Laude ◽  
Kara Anne Tan ◽  
Jianbin Ding ◽  
Elizabeth Wong ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Choroidal Thickness ◽  
Structural Changes ◽  
Mean Difference ◽  
Enhanced Depth Imaging ◽  
Diabetic Patients ◽  
Depth Imaging ◽  
Before And After ◽  
Patients With Diabetes ◽  
Imaging Optical Coherence Tomography

Objective: To study the structural changes in the choroid of diabetic patients following cataract surgery, using choroidal vascularity index and choroidal thickness. Methods: A prospective case–control study was conducted in 18 diabetic and 18 non-diabetic patients undergoing cataract surgery (phacoemulsification) in one eye. Enhanced depth imaging optical coherence tomography images were obtained before and after surgery. Niblack’s image binarization of images was performed to derive the choroidal vascularity index. Independent sample T-test compared the differences of choroidal vascularity index and choroidal thickness between diabetic and non-diabetic patients. Results: The baseline choroidal vascularity index was significantly lower in diabetic patients for both operated (mean difference vs non-diabetic: 0.0184, 95% CI: 0.004–0.0324, p = 0.012) and non-operated (mean difference vs non-diabetic: 0.0145, 95% CI: 0.003–0.0256, p = 0.012) eyes. Choroidal thickness increased following cataract surgery (diabetes: mean difference = 12.4, 95% CI: 0.70–24.0, adjusted p = 0.036; non-diabetic: mean difference = 21.0, 95% CI: 4.39–37.6, adjusted p = 0.011). Conclusion: Diabetic patients have reduced choroidal vascularity index than non-diabetic patients, suggestive of possible reduction in choroidal vascularity in diabetes. Choroidal thickness increased following cataract surgery in both diabetic and non-diabetic patients.

Choroidal thickness evaluation in paediatric patients with adenotonsillar hypertrophy

2017 ◽  
Vol 131 (9) ◽  
pp. 768-772
Author(s):  
A Yenigun ◽  
A Elbay ◽  
A M Hafiz ◽  
O Ozturan
Keyword(s):  
Choroidal Thickness ◽  
Enhanced Depth Imaging ◽  
Control Group ◽  
Healthy Children ◽  
Depth Imaging ◽  
Adenotonsillar Hypertrophy ◽  
Paediatric Patients ◽  
Healthy Control ◽  
Imaging Optical Coherence Tomography ◽  
Thickness Measurements

AbstractObjective:To investigate choroidal thickness using enhanced-depth imaging optical coherence tomography in paediatric patients with adenotonsillar hypertrophy, with comparison to healthy children, three months after adenotonsillectomy.Methods:The patients were assigned to three groups: an adenotonsillar hypertrophy group, an adenotonsillectomy group and a healthy control group. In all groups, subfoveal, temporal and nasal choroidal thickness measurements were taken.Results:In the subfoveal, temporal and nasal regions, choroidal tissue was found to be significantly thinner in adenotonsillar hypertrophy children than healthy children (p = 0.012, p = 0.027 and p = 0.020). The subfoveal and temporal choroidal thickness measurements of adenotonsillar hypertrophy group cases were significantly decreased compared to those in the adenotonsillectomy group (p = 0.038 and p = 0.048).Conclusion:There was a significant association between decreased choroidal thickness and adenotonsillar hypertrophy. Adenotonsillar hypertrophy may play an important role in decreased choroidal thickness.

scholarly journals A Meta-Analysis of Choroidal Thickness Changes in Unilateral Amblyopia

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Yanli Liu ◽  
Yi Dong ◽  
Kanxing Zhao
Keyword(s):  
Choroidal Thickness ◽  
Primary Outcome ◽  
Weighted Mean Difference ◽  
Meta Analysis ◽  
Enhanced Depth Imaging ◽  
Weighted Mean ◽  
Cross Sectional ◽  
Depth Imaging ◽  
Imaging Optical Coherence Tomography ◽  
And Control

Purpose. To date, the topic of amblyopic changes remains controversial. Therefore, a systematic review and meta-analysis were carried out to evaluate choroidal changes in unilateral amblyopia. Methods. Major literature databases were searched for amblyopia-relevant studies. Using enhanced depth imaging optical coherence tomography (EDI-OCT), the primary outcome parameters examined were subfoveal choroidal thickness (SFCT) and different choroidal thickness (CT) positions. Efficacy estimates were evaluated by weighted mean difference (WMD) and 95% confidence interval (CI) for choroidal-associated changes. We performed subgroup analysis and metaregression analysis to examine potential sources of heterogeneity. Results. Eleven cross-sectional studies that included a total of 768 participants were identified. The amblyopic eye SFCT was thicker than that of the fellow and control (normal) eyes (WMDamblyopia versus fellow=49.24, 95% CI of 30.22 to 68.27, p<0.001; WMDamblyopia versus control=54.51, 95% CI of 32.17 to 76.85, p<0.001). There were no differences between the fellow and control eyes (WMD=13.81, 95% CI of 1.16 to 28.77, p=0.071). Subgroup and metaregression analyses indicated that the OCT type was the main source of heterogeneity. Conclusions. The CT in the amblyopic eyes was thicker than that in the fellow and control eyes.

The effect of obesity and insulin resistance on macular choroidal thickness in a pediatric population as assessed by enhanced depth imaging optical coherence tomography

2018 ◽  
Vol 31 (8) ◽  
pp. 855-860 ◽  
Author(s):  
Pinar Topcu-Yilmaz ◽  
Nesibe Akyurek ◽  
Erkan Erdogan
Keyword(s):  
Insulin Resistance ◽  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Enhanced Depth Imaging ◽  
Model Assessment ◽  
Optical Coherence ◽  
Obese Children ◽  
Depth Imaging ◽  
Imaging Optical Coherence Tomography ◽  
Thickness Measurements

Abstract Background: The purpose of this study was to evaluate the macular choroidal thickness in obese children with and without insulin resistance (IR). Methods: Thirty-six patients with obesity and 26 healthy volunteers were included in this cross-sectional study. The choroidal thickness was measured with enhanced depth imaging optical coherence tomography (EDI-OCT) at the fovea and at positions 500 μm, 1000 μm, 1500 μm nasal and temporal to the fovea. The choroidal thickness measurements of the groups were compared and the correlation between the homeostasis model assessment of insulin resistance (HOMA-IR) and choroidal thickness values was evaluated. Results: The average choroidal thickness in the obese group was significantly lower than that of controls at locations 1000 μm (303.31±58.52 vs. 340.58±69.47, p=0.026) and 1500 μm (284.14±65.06 vs. 336.85±71.37, p=0.004) temporal to the fovea. A subgroup analysis depending on the presence of IR revealed that the choroidal thickness measurements at all positions were thinner in obese children without IR compared to children with IR and healthy controls. This thinning reached a statistical significance at locations 500 μm temporal, 1000 μm temporal and 1500 μm temporal to the fovea (p=0.03, p=0.009 and p=0.006; respectively). There was a moderate correlation between the choroidal thickness measurements and HOMA-IR values (r-values between 0.37 and 0.48; p<0.05). Conclusions: Our results suggest that obesity and IR may have an influence on the choroidal thickness in children. Longitudinal studies will clarify whether these choroidal changes are progressive and are a sign of microvascular dysfunction in childhood obesity.

Corneal cross-linking for keratoconus: Evaluation of the retina and choroid

2021 ◽  
pp. 112067212110213
Author(s):  
Kobra Nasrollahi ◽  
Fatemeh Razmjoo ◽  
Morteza Naderan ◽  
Alireza Peyman
Keyword(s):  
Choroidal Thickness ◽  
Structural Changes ◽  
Enhanced Depth Imaging ◽  
Cross Linking ◽  
Depth Imaging ◽  
Significant Difference ◽  
Corrected Distance Visual Acuity ◽  
Before And After ◽  
Imaging Optical Coherence Tomography ◽  
Choroidal Volume

Purpose: To investigate the possible structural changes of the central choroid and retina after collagen cross-linking (CXL) in patients with progressive keratoconus (KCN). Methods: Twenty-five eyes of 25 patients were included in this study. Patients underwent enhanced depth imaging optical coherence tomography (EDI-OCT) before and 1 month after CXL. The values for central macular thickness (CMT), subfoveal choroidal thickness (CHT), and choroidal volume (CHV) were evaluated. Results: CMT before and after CXL was 263.24 ± 16.25 μm and 263.20 ± 16.51 μm, respectively ( p = 0.98). CHT was 362.08 ± 36.80 μm and 367.84 ± 33.67 μm before and after CXL, respectively ( p = 0.26). CHV was 8.74 ± 0.33 mm3 and 8.68 ± 0.36 mm3 before and after CXL, respectively ( p = 0.11). There was no significant difference in the corrected distance visual acuity before and after CXL (0.06 ± 0.05 and 0.05 ± 0.05 logMAR, respectively, p = 0.65). Conclusion: Central retinal and choroidal thicknesses are not changed after corneal cross- linking.

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