scholarly journals Multiorgan Failure and Refractory Lactic Acidosis due toPasteurella multocidaSepticemia in a Patient with No Animal Exposure

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Damaris Pena ◽  
Yaneidy Santana ◽  
Jose Perez Lara ◽  
Efrain Gonzalez ◽  
Misbahuddin Khaja
Keyword(s):  
Septic Shock ◽  
Lactic Acidosis ◽  
Pasteurella Multocida ◽  
Cardiopulmonary Arrest ◽  
Multiorgan Failure ◽  
Severe Respiratory Distress ◽  
Ventilator Support ◽  
Case Presentation ◽  
History Of ◽  
Animal Exposure

Introduction.Pasteurella multocidais a gram-negative coccobacillus pathogenic to animals. It can cause infection in humans by a bite, scratch, or lick from a cat or dog.P. multocidacan cause a variety of infections in humans, including cellulitis, osteomyelitis, endocarditis, peritonitis, and septic shock.Case Presentation. A 56-year-old male presented to our hospital with a 2-day history of fever, abdominal pain, nausea, and vomiting. He denied exposure to cats, dogs or other pets. He had severe respiratory distress requiring ventilator support, profound septic shock requiring multiple vasopressors, severe lactic acidosis, and renal failure requiring emergent hemodialysis. Blood cultures confirmed the presence ofP. multocida. The patient subsequently died of cardiopulmonary arrest due to multiorgan failure with refractory shock.Conclusion.P. multocidasepticemia can lead to septic shock. Early identification of this organism may decrease mortality. Although our patient had no known cat or dog exposure, physicians should enquire about a history of animal exposure when a patient presents with an infection with no obvious cause.

scholarly journals Severe pneumonia leading to death in an achondroplasic infant: a rare case report

2018 ◽  
Vol 5 (2) ◽  
pp. 681
Author(s):  
Mankiran K. Matharoo ◽  
Gursharn S. Narang
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Respiratory Infections ◽  
Cardiopulmonary Arrest ◽  
Multiorgan Failure ◽  
Failure To Thrive ◽  
Severe Pneumonia ◽  
Severe Respiratory Distress ◽  
Rare Case Report ◽  
History Of

This report concerns a 9-month-old male with achondroplasia presenting with severe respiratory distress having history of frequent respiratory infections, developmental delay and failure to thrive. Child had septicemia and ended up in multiorgan failure, ultimately leading to death due to cardiopulmonary arrest.

scholarly journals Sudden Infant Death Due to Postvaccinal Myocarditis: A Case Report

2021 ◽  
Vol 11 (3) ◽  
pp. 32227-32227
Author(s):  
Babak Salahshour ◽  
◽  
Sajjad Sadeghi ◽  
Ahmad Sajadianfar ◽  
Kambiz Soltaninejad ◽  
...  
Keyword(s):  
Infant Death ◽  
Causality Assessment ◽  
Histopathological Examination ◽  
Cardiopulmonary Arrest ◽  
Inflammatory Cells ◽  
Sudden Infant Death ◽  
Cardiac Monitoring ◽  
Sudden Infant ◽  
Case Presentation ◽  
History Of

Background: Vaccination is a fundamental strategy in public health for controlling and eradicating infectious diseases. However, the undesirable Adverse Events Following Immunization (AEFI) should be effectively monitored, prevented, and managed in societies. Previously, Sudden Infant Death (SID) has been reported as a serious AEFI. We present a rare case of SID in an 18-month-old girl due to severe myocarditis following vaccination. Case Presentation: An 18-month-old girl presented to the Emergency Department (ED) with a history of the injection of Diphtheria-Tetanus-Whole Cell Pertussis (DTwP); Measles, Mumps, and Rubella (MMR), and oral poliovirus vaccines. She expired one-hour post ED admission after the episodes of vomiting and cardiopulmonary arrest. Postmortem histopathological examination signified marked congestion and the destruction of muscle fibers in the myocardium with inflammatory cells infiltration predominantly eosinophils. Given the postmortem histopathological findings, the cause of death was concluded as severe myocarditis following vaccination. Finally, the causality assessment was performed according to the Naranjo scale; the relevant data revealed a probable association in this regard (Naranjo score 6). Conclusion: Myocarditis is a rare and probable AEFI; thus, cardiac monitoring should be recommended as a diagnostic measure in managing postvaccinal adverse effects.

scholarly journals A Case of Pasteurella Multocida Pneumonia, Bacteremia, and Septic Shock

2021 ◽  
Author(s):  
Wesley Tang ◽  
Sulagna Das ◽  
James Galbraith
Keyword(s):  
Septic Shock ◽  
Pasteurella Multocida ◽  
Relevant Literature ◽  
Domestic Animals ◽  
Immunocompetent Patient ◽  
Hodgkin's Lymphoma ◽  
Human Pathogen ◽  
Pulmonary Lesions ◽  
History Of ◽  
Immunocompromised State

Abstract Pasteurella multocida is a ubiquitous organism found in the oropharynx of healthy domestic animals, especially dogs and cats. It is most known as a human pathogen, reported after animal bite incidents. In atraumatic infections, Pasteurella has been associated with patients in an immunocompromised state, such as those with Hodgkin’s lymphoma, patients with known cirrhosis, or those with preexisting cavitary pulmonary lesions. It is rare to isolate Pasteurella in an immunocompetent patient without known trauma. Here, we present a case of Pasteurella multocida pneumonia, bacteremia, and septic shock in an individual without a history of an animal bite, with a review of relevant literature.

scholarly journals Spontaneous Intracerebral Hemorrhage (ICH) associated with pregnancy and SARS-CoV-2 infection: a case report

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Parisa Dini ◽  
Soheila Aminimoghaddam ◽  
Zahra Mirzaasgari ◽  
Neda Rahimian ◽  
Samaneh Tanhapour Khotbehsara ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Multiorgan Failure ◽  
Pregnant Patient ◽  
Risk Groups ◽  
Pulmonary Complications ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Case Presentation ◽  
Hemorrhagic Events ◽  
History Of

Abstract Background Coronavirus Disease 2019 (COVID-19) is predominately known as a respiratory disease associated with pneumonia, acute respiratory distress syndrome and multiorgan failure. However, extra-pulmonary complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are increasingly being recognized. In this regard, some studies implied the hemostatic and vascular involvements in patients with SARS-CoV-2 infection. Case presentation We describe a case of spontaneous Intracerebral Hemorrhage (ICH) in a pregnant patient with COVID-19 and history of cesarean section a week before the occurrence of ICH. The patient underwent emergent craniotomy with acceptable outcome. Hemorrhagic events, including ICH, may happen during COVID-19 infection with several possible mechanisms. Conclusion COVID-19 patients, especially high-risk groups, are at a risk of intracranial hemorrhage. Therefore, close follow-up must be maintained and hemorrhagic events must be kept in mind in these cases.

scholarly journals Fatal septic shock due to Capnocytophaga canimorsus bacteremia masquerading as COVID-19 pneumonia - a case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Eva Christina Meyer ◽  
Sabine Alt-Epping ◽  
Onnen Moerer ◽  
Benedikt Büttner
Keyword(s):  
Septic Shock ◽  
Multiorgan Failure ◽  
Initial Therapy ◽  
Nucleic Acid Amplification ◽  
Cytokine Storm ◽  
Skin Injury ◽  
Capnocytophaga Canimorsus ◽  
Case Presentation ◽  
Microbial Detection ◽  
Point Of Entry

Abstract Background Capnocytophaga canimorsus (C. canimorsus) infections are rare and usually present with unspecific symptoms, which can eventually end in fatal septic shock and multiorgan failure. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) related coronavirus disease 2019 (COVID-19), on the other hand, is predominantly characterized by acute respiratory failure, although other organ complications can occur. Both infectious diseases have in common that hyperinflammation with a cytokine storm can occur. While microbial detection of C. canimorsus in blood cultures can take over 48 h, diagnosis of SARS-CoV-2 is facilitated by a widely available rapid antigen diagnostic test (Ag-RDT) the results of which are available within half an hour. These Ag-RDT results are commonly verified by a nucleic acid amplification test (NAAT), whose results are only available after a further 24 h. Case presentation A 68-year-old male patient with the diagnosis of COVID-19 pneumonia was referred to our Intensive Care Unit (ICU) from another hospital after testing positive on an Ag-RDT. While the initial therapy was focused on COVID-19, the patient developed a fulminant septic shock within a few hours after admission to the ICU, unresponsive to maximum treatment. SARS-CoV-2 NAATs were negative, but bacteremia of C. canimorsus was diagnosed post-mortem. Further anamnestic information suggest that a small skin injury caused by a dog leash or the subsequent contact of this injury with the patient’s dog could be the possible point of entry for these bacteria. Conclusion During the acute phase of hyperinflammation and cytokine storm, laboratory results can resemble both, sepsis of bacterial origin or SARS-CoV-2. This means that even in the light of a global SARS-CoV-2 pandemic, where this diagnosis provides the most salient train of thoughts, differential diagnoses must be considered. Ag-RDT can contribute to early detection of a SARS-CoV-2 infection, but false-positive results may cause fixation errors with severe consequences for patient outcome.

scholarly journals Pasteurella multocidaSepticemia in a Patient with Cirrhosis: An Autopsy Report

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Takuma Yamamoto ◽  
Takahiro Umehara ◽  
Takehiko Murase ◽  
Kazuya Ikematsu
Keyword(s):  
Risk Factors ◽  
Septic Shock ◽  
Differential Diagnosis ◽  
Pasteurella Multocida ◽  
Potential Danger ◽  
Autopsy Case ◽  
Patient History ◽  
Source Of Infection ◽  
Autopsy Report ◽  
Animal Exposure

More people are keeping pets in their homes but may not be sufficiently aware of the potential danger from infections. We report an autopsy case of a 57-year-old man affected by cirrhosis. Septic shock withPasteurella multocidapneumonia was the cause of his death.P. multocidawas the source of infection via the respiratory tract and caused pneumonia. Cirrhosis is one of the risk factors forP. multocidainfection. A detailed patient history about animal exposure should be obtained and a differential diagnosis ofP. multocidainfection must be kept in mind.

scholarly journals Pasteurella multocidaOsteomyelitis: An Unusual Case Presentation

1996 ◽  
Vol 7 (2) ◽  
pp. 137-139 ◽  
Author(s):  
Herbert P von Schroeder ◽  
Robert S Bell
Keyword(s):  
Pasteurella Multocida ◽  
Unusual Case ◽  
Healthy Male ◽  
Radiographic Appearance ◽  
Case Presentation ◽  
Atypical Features ◽  
Animal Contact ◽  
History Of ◽  
Osteoclast Activation ◽  
High Degree

A healthy male farm employee developed an unusual infection caused byPasteurella multocida. Atypical features included the chronic nature of the infection, the development of osteomyelitis of the tibia without direct animal inoculation, and lack of fever and leukocytosis. Radiographic appearance ofP multocidaosteomyelitis may be the result of osteoclast activation and can be confused with musculoskeletal tumour.P multocidainfection requires a high degree of suspicion, and should be considered in cases of farm- or animal-related injuries even if there is no history of direct animal contact.

Aspergillus Spondylodiscitis After Spinal Stenosis Surgery: A Case Report

2020 ◽  
Vol 5 (3 And 4) ◽  
pp. 155-160
Author(s):  
Mohsen Aghapoor ◽  
◽  
Babak Alijani Alijani ◽  
Mahsa Pakseresht-Mogharab ◽  
◽  
...  
Keyword(s):  
Antifungal Drugs ◽  
The Body ◽  
Lower Limbs ◽  
Lumbar Pain ◽  
Case Presentation ◽  
Delay In Diagnosis ◽  
Death Case ◽  
Therapeutic Results ◽  
History Of ◽  
Probable Diagnosis

Background and Importance: Spondylodiscitis is an inflammatory disease of the body of one or more vertebrae and intervertebral disc. The fungal etiology of this disease is rare, particularly in patients without immunodeficiency. Delay in diagnosis and treatment of this disease can lead to complications and even death. Case Presentation: A 63-year-old diabetic female patient, who had a history of spinal surgery and complaining radicular lumbar pain in both lower limbs with a probable diagnosis of spondylodiscitis, underwent partial L2 and complete L3 and L4 corpectomy and fusion. As a result of pathology from tissue biopsy specimen, Aspergillus fungi were observed. There was no evidence of immunodeficiency in the patient. The patient was treated with Itraconazole 100 mg twice a day for two months. Pain, neurological symptom, and laboratory tests improved. Conclusion: The debridement surgery coupled with antifungal drugs can lead to the best therapeutic results.

An Obscure Colon Dilatation and its Underlying Cause: Case Report and Literature Review

2020 ◽  
pp. 1-5
Author(s):  
Anton Stift ◽  
Kerstin Wimmer ◽  
Felix Harpain ◽  
Katharina Wöran ◽  
Thomas Mang ◽  
...  
Keyword(s):  
Case Report ◽  
Sigmoid Colon ◽  
Immunohistochemical Staining ◽  
Late Onset ◽  
Hirschsprung Disease ◽  
Endoscopic Examination ◽  
Case Presentation ◽  
Idiopathic Megacolon ◽  
History Of ◽  
Cells Of Cajal

Introduction: Congenital as well as acquired diseases may be responsible for the development of a megacolon. In adult patients, Clostridium difficile associated infection as well as late-onset of Morbus Hirschsprung disease are known to cause a megacolon. In addition, malignant as well as benign colorectal strictures may lead to intestinal dilatation. In case of an idiopathic megacolon, the underlying cause remains unclear. Case Presentation: We describe the case of a 44-year-old male patient suffering from a long history of chronic constipation. He presented himself with an obscurely dilated large intestine with bowel loops up to 17 centimeters in diameter. Radiological as well as endoscopic examination gave evidence of a spastic process in the sigmoid colon. The patient was treated with a subtotal colectomy and the intraoperative findings revealed a stenotic stricture in the sigmoid colon. Since the histological examination did not find a conclusive reason for the functional stenosis, an immunohistochemical staining was advised. This showed a decrease in interstitial cells of Cajal (ICC) in the stenotic part of the sigmoid colon. Discussion: This case report describes a patient with an idiopathic megacolon, where the underlying cause remained unclear until an immunohistochemical staining of the stenotic colon showed a substantial decrease of ICCs. Various pathologies leading to a megacolon are reviewed and discussed.

Pulmonary Rehabilitation After Lobectomy On Pulmonary Aspergilloma: Case Report

2019 ◽  
pp. 35-41
Author(s):  
Andwi Setiawan Kokok ◽  
Selly Christina Anggoro ◽  
Siti Chandra Widjanantie
Keyword(s):  
Pulmonary Rehabilitation ◽  
Peak Flow ◽  
Case Presentation ◽  
Rehabilitation Programs ◽  
Abnormal Chest ◽  
History Of ◽  
Postural Correction ◽  
Chronic Pulmonary Aspergillosis ◽  
Pulmonary Aspergilloma ◽  
Breathing Retraining

Introduction: Complete resection of aspergilloma in chronic pulmonary aspergillosis (CPA), may has several health problem after surgery berupa sesak napas, batuk yang tidak efektif. Methods: A case presentation of 45 years old woman, after lobectomy on right upper of lung due to aspergilloma, with history of cough and haemoptysis for 3 months. Pulmonary Rehabilitation were breathing retraining exercise (BE), mobilization technique (MT), chest mobility exercise (CM), active cycle breathing technique (ACBT), postural correction exercise (PC) for three weeks. Results: There were dyspnea, peak flow rate (PFR:60-70-60), peak cough flow (PCF: 70-90-60 L/m), and abnormal chest expansion (CE: 2.5 – 3 – 2) cm. After three weeks of Pulmonary Rehabilitation, there were no dyspnea, increased the PCF: 193L/m, and CE: 2.5-4 -3. Conclusion: Pulmonary Rehabilitation programs for three weeks were relieved dyspnea, increased cough capacity and CE.

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