scholarly journals Prevalence of Pruritus in Cutaneous Lupus Erythematosus: Brief Report of a Multicenter, Multinational Cross-Sectional Study

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Dominik Samotij ◽  
Justyna Szczęch ◽  
Carolyn J. Kushner ◽  
Mohammad Rafiqul Mowla ◽  
Aleksandra Dańczak-Pazdrowska ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Clinical Characteristics ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Cutaneous Lupus Erythematosus ◽  
Connective Tissue Diseases ◽  
Well Being ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Pruritus is an important symptom frequently accompanying various inflammatory skin conditions. Some recent data have indicated that it may also be associated with autoimmune connective tissue diseases, including systemic sclerosis and dermatomyositis; however, studies on the prevalence and clinical characteristics of pruritus in CLE are limited. We have performed a multinational, prospective, cross-sectional study in order to assess the prevalence and intensity of pruritus in adult patients suffering from various subtypes of CLE. After developing a questionnaire assessing various aspects of pruritus, we have surveyed 567 patients with cutaneous involvement during the course of LE regarding the presence and intensity of pruritus. Pruritus was present in 425 of all patients (75.0%) and was most frequently reported by subjects with acute CLE (82.1%), followed by chronic CLE (78.8%), subacute CLE (65.9%), and intermittent CLE (55.6%) (p<0.001). Based on the Numerical Rating Scale, the severity of itch was mild, moderate, and severe in 264 (62.1%), 98 (23.1%), and 63 (14.8%) patients, respectively. The highest mean pruritus intensity was reported by subjects with hypertrophic LE (5.1±3.0 points) followed by generalized discoid LE (3.6±3.0 points), subacute CLE (3.0±3.0 points), chilblain LE (3.0±1.0 points), localized discoid LE (2.6±2.0 points), intermittent CLE (2.6±3.0 points), acute CLE (2.5±1.2 points), and lupus erythematosus profundus (1.9±2.7 points). In conclusion, pruritus is a frequent phenomenon in CLE; however, in most patients it is of mild severity. Further studies are needed to better characterize its clinical characteristics and influence on patients’ well-being.

scholarly journals Spondyloarthropathies in Autoimmune Diseases and Vice Versa

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Oscar M. Pérez-Fernández ◽  
Rubén D. Mantilla ◽  
Paola Cruz-Tapias ◽  
Alberto Rodriguez-Rodriguez ◽  
Adriana Rojas-Villarraga ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Systemic Lupus Erythematosus ◽  
Autoimmune Diseases ◽  
Lupus Erythematosus ◽  
Clinical Characteristics ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Systemic Lupus ◽  
Two Phase ◽  
Cross Sectional

Polyautoimmunity is one of the major clinical characteristics of autoimmune diseases (ADs). The aim of this study was to investigate the prevalence of ADs in spondyloarthropathies (SpAs) and vice versa. This was a two-phase cross-sectional study. First, we examined the presence of ADs in a cohort of patients with SpAs (N=148). Second, we searched for the presence of SpAs in a well-defined group of patients with ADs (N=1077) including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Sjögren’s syndrome (SS). Among patients with SpAs, ankylosing spondylitis was observed in the majority of them (55.6%). There were two patients presenting with SS in the SpA group (1.4%) and 5 patients with autoimmune thyroiditis (3.5%). The global prevalence of ADs in SpAs was 4.86%. In the ADs group, there were 5 patients with SpAs (0.46%). Our results suggest a lack of association between SpAs and ADs. Accordingly, SpAs might correspond more to autoinflammatory diseases rather than to ADs.

scholarly journals Association between telecommuting environment and low back pain among Japanese telecommuting workers: A cross-sectional study

2021 ◽  
Author(s):  
Ryutaro Matsugaki ◽  
Keiji Muramatsu ◽  
Seiichiro Tateishi ◽  
Tomohisa Nagata ◽  
Mayumi Tsuji ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Cross Sectional Study ◽  
Mixed Effects ◽  
Low Back ◽  
Sectional Study ◽  
Cross Sectional ◽  
Numerical Rating

Objectives: We evaluated the relationship between telecommuting environment and low back pain (LBP) among desk-based workers in Japan. Methods: This cross-sectional study included 3,663 desk-based, telecommuting workers. LBP was assessed using a 0 to 10 numerical rating scale. The telecommuting environment was evaluated using subjective questions. Mixed-effects logistic regression analysis was used. Results: Mixed-effects logistic model results revealed that not having a place or room to concentrate on work, desk not well-lit enough for work, not having enough space on the desk to work, not having enough legroom, and not having comfortable temperature and humidity conditions in the workspace were significantly associated with higher odds of LBP. Conclusions: Our findings suggest that telecommuting environment is associated with the prevalence of LBP.

scholarly journals Biopsychosocial factors and global perceived effect scale on the subject with chronic pain: an analytic cross-sectional study

2020 ◽  
pp. 1-5
Author(s):  
Graziella Cristina Roque ◽  
Tiago Tsunoda del Antonio ◽  
Fabrício José Jassi ◽  
Thais Cristina Chaves
Keyword(s):  
Chronic Pain ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Pain Catastrophizing ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Fear Avoidance Beliefs ◽  
The Subject

Background: Chronic pain is an emotional and sensorial experience that triggers functional incapacity guided especially by the biopsychosocial changes, that lead to its aggravation directly affecting the recovery of the patient. Objective: To verify the presence of biopsychosocial factors in the subject with chronic pain on the physiotherapeutic care undergone in a clinical physiotherapy school. Method: A cross-sectional study, conducted in the physiotherapy clinic of the Health Sciences Center of the Universidade Estadual do Norte do Paraná, in which were evaluated 26 subjects with chronic pain through the Pain Numerical Rating Scale; Hospital Anxiety and Depression Scale; Pain Catastrophizing Scale; Fear Avoidance Beliefs Questionnaire; and Global Perceived Effect Scale. The statistical analysis had significance value of P≤0.05. Results: Even with reduction of pain intensity with P=0.04, the values do not indicate clinically relevant difference. The global perceived effect scale does not indicate a significant improvement of the subjects; however this is justified because the treatment does not address biopsychosocial aspects, being a technical approach. Conclusion: The treatment of chronic pain associated with a biopsychosocial approach would be the most indicated in clinical practice.

scholarly journals Association between severity of depressive symptoms and chronic knee pain in Korean adults aged over 50 years: a cross-sectional study using nationally representative data

BMJ Open ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. e032451
Author(s):  
Su-Bin Han ◽  
Sook-Hyun Lee ◽  
In-Hyuk Ha ◽  
Eun-Jung Kim
Keyword(s):  
Depressive Symptoms ◽  
Knee Pain ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Strong Association ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Chronic Knee Pain ◽  
Depressed Group

ObjectivesTo identify the association between the presence and severity of depressive symptoms and those of chronic knee pain.DesignA retrospective cross-sectional study.ParticipantsWe used data from the sixth Korea National Health and Nutrition Examination Survey (KNHANES VI-2) performed in 2014. Overall, 7550 patients were included in the KNHANES VI-2.Outcome measuresParticipants were asked whether they had chronic knee pain, and each answer was either ‘yes’ or ‘no’. Patient Health Questionnaire-9 (PHQ-9) was used as a screening tool for depressive symptoms, and PHQ-9 scores of 10 or higher was classified as the depressed group. In total, 527 patients reported that they had pain in their knee, of whom 91 also had depressive symptoms.ResultsThe prevalence of chronic knee pain in the Korean population aged over 50 years was 19.8%. Multiple logistic regression was conducted after adjustment for sex, age, smoking, alcohol drinking, education level, household income, physical activity, sleep duration and comorbidity. The analysis revealed a significant association between depressive symptoms and chronic knee pain (adjusted OR=2.333, p<0.001). In contrast, the severity of depressive symptoms was linearly correlated with the intensity of chronic knee pain (p for trend <0.001). In participants with no chronic knee pain (Numerical Rating Scale; NRS=0) or mild chronic knee pain (NRS=1–4), the prevalence of moderate and severe depressive symptoms was 3.4% and 0.6%, respectively. However, in those with severe chronic knee pain (NRS=8–10), there was a higher prevalence of moderate and severe depressive symptoms (10.1% and 5.8%, respectively) (p<0.001).ConclusionsA strong association was observed between the presence and severity of depressive symptoms and the presence of chronic knee pain. The association became stronger with higher levels of depressive symptoms, indicating a positive correlation between depressive symptoms severity and chronic knee pain.

Clinical characteristics of itch in cutaneous lupus erythematosus: A prospective, multicenter, multinational, cross-sectional study

Lupus ◽  
2021 ◽  
pp. 096120332110160
Author(s):  
Dominik Samotij ◽  
Justyna Szczęch ◽  
Emiliano Antiga ◽  
Diletta Bonciani ◽  
Marzia Caproni ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Cutaneous Lupus Erythematosus ◽  
Cross Sectional Study ◽  
Skin Damage ◽  
Sectional Study ◽  
Systemic Lupus ◽  
Cross Sectional ◽  
Cutaneous Lupus

Objective Pruritus is an important symptom frequently accompanying various inflammatory skin conditions and some recent data indicated that it may be associated with autoimmune connective tissue diseases. The aim of this study was to assess the frequency and clinical presentation of itch in CLE. Methods A multinational, prospective, cross-sectional study was performed to assess the prevalence, intensity and clinical characteristic of pruritus in various subtypes of CLE. A total of 153 patients with active CLE lesions were included. Their age ranged between 17 and 82 years (mean 49.8 ± 15.4 years), and 115 patients (75.2%) were women. The disease activity and damage were assessed according to the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI). Pruritus severity was assessed with Numeric Rating Scale (NRS) and the 12-Item Pruritus Severity Scale. Dermatology Life Quality Index and EQ-5D questionnaire were used to measure quality of life. Results Pruritus was present in 116 (76.8%) of patients of whom half had NRS scoring equal or above 4 points indicating moderate or severe pruritus. Most commonly itch was localized on the scalp, face (excluding ears and nose) and arms (40.5%, 36.2%, 31.9%, respectively). Sensations connected with pruritus were most frequently described as burning, tingling and like ants crawling feeling, but 31.9% patients described it as “pure itch”. More than half of patients reported that pruritus was present every day, and it was most frequent during the evenings. The pruritus scoring and the CLASI activity score were significantly correlated (r = 0.42, p = 0.0001), while no correlation was found with the CLASI damage score (p = 0.16). Both the maximum and average itch intensity were correlated with systemic lupus erythematosus (SLE) activity measured with the Systemic Lupus Erythematosus Disease Activity Index. Conclusions Pruritus is a common, but frequently overlooked symptom of CLE. Its intensity correlates with the activity of CLE, but not with the skin damage. In more than a half of patients it occurs on a daily basis. The correlation between the intensity of pruritus and the activity of the skin lesions and the systemic involvement indicate that pruritus could be an individual indicator of both SLE and CLE activity.

scholarly journals Anxious temperament and cyberchondria as mediated by fear of COVID-19 infection: A cross-sectional study

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255750
Author(s):  
Włodzimierz Oniszczenko
Keyword(s):  
Rating Scale ◽  
Numerical Rating Scale ◽  
Linear Regression Analysis ◽  
Correlation Coefficients ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Severity Scale ◽  
Cross Sectional ◽  
Numerical Rating ◽  
Positive Correlations

This study’s main goal was to evaluate the association between anxious temperament and the fear of COVID-19-related self-infection and infection in loved ones (family members, friends, relatives) and cyberchondria. The sample consisted of 499 men and women aged between 18 and 72 who were gathered from the general population via an online recruitment platform. A numerical rating scale comprising 11 degrees of fear was used to assess participants’ COVID-19-related fear, and affective temperaments were evaluated using Akiskal’s Temperament Evaluation of the Memphis, Pisa, Paris and San Diego Autoquestionnaire (TEMPS-A) scales. Cyberchondria was assessed using McElroy and Shevlin’s Cyberchondria Severity Scale (CSS). Small to medium positive correlations were found between depressive, cyclothymic, irritable and anxious temperaments and cyberchondria and between depressive and anxious temperaments and COVID-19 fears. However, no correlation was observed between the hyperthymic temperament and cyberchondria. Cyberchondria positively correlated with both COVID-19 fears scales, though the correlation coefficients were medium. Based on the results of linear regression analysis, only anxious temperament and COVID-19 fear of self-infection were significant predictors of cyberchondria. The analysis also revealed a significant indirect effect of anxious temperament on cyberchondria through fear of COVID-19 self-infection as a mediator between anxious temperament and cyberchondria.

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