scholarly journals Lean Body Weight-Tailored Iodinated Contrast Injection in Obese Patient: Boer versus James Formula

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Damiano Caruso ◽  
Domenico De Santis ◽  
Flaminia Rivosecchi ◽  
Marta Zerunian ◽  
Nicola Panvini ◽  
...  
Keyword(s):  
Body Weight ◽  
Portal Vein ◽  
Contrast Enhancement ◽  
Lean Body Weight ◽  
Obese Patients ◽  
Iodinated Contrast ◽  
Significant Difference ◽  
Formula Group ◽  
Group A ◽  
Group B

Purpose. To prospectively compare the performance of James and Boer formula in contrast media (CM) administration, in terms of image quality and parenchymal enhancement in obese patients undergoing CT of the abdomen. Materials and Methods. Fifty-five patients with a body mass index (BMI) greater than 35 kg/m2 were prospectively included in the study. All patients underwent 64-row CT examination and were randomly divided in two groups: 26 patients in Group A and 29 patients in Group B. The amount of injected CM was computed according to the patient’s lean body weight (LBW), estimated using either Boer formula (Group A) or James formula (Group B). Patient’s characteristics, CM volume, contrast-to-noise ratio (CNR) of liver, aorta and portal vein, and liver contrast enhancement index (CEI) were compared between the two groups. For subjective image analysis readers were asked to rate the enhancement of liver, kidneys, and pancreas based on a 5-point Likert scale. Results. Liver CNR, aortic CNR, and portal vein CNR showed no significant difference between Group A and Group B (all P≥0.177). Group A provided significantly higher CEI compared to Group B (P=0.007). Group A and Group B returned comparable overall subjective enhancement values (3.54 and vs 3.20, all P≥0.199). Conclusions. Boer formula should be the method of choice for LBW estimation in obese patients, leading to an accurate CM amount calculation and an optimal liver contrast enhancement in CT.

scholarly journals Lean body weight versus total body weight to calculate the iodinated contrast media volume in abdominal CT: a randomised controlled trial

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Moreno Zanardo ◽  
Fabio Martino Doniselli ◽  
Anastassia Esseridou ◽  
Massimiliano Agrò ◽  
Nicol Antonina Rita Panarisi ◽  
...  
Keyword(s):  
Body Weight ◽  
Contrast Media ◽  
Controlled Trial ◽  
Total Body Weight ◽  
Lean Body Weight ◽  
Iodinated Contrast Media ◽  
Abdominal Ct ◽  
Iodinated Contrast ◽  
Significant Difference ◽  
Total Body

Abstract Objectives Iodinated contrast media (ICM) could be more appropriately dosed on patient lean body weight (LBW) than on total body weight (TBW). Methods After Ethics Committee approval, trial registration NCT03384979, patients aged ≥ 18 years scheduled for multiphasic abdominal CT were randomised for ICM dose to LBW group (0.63 gI/kg of LBW) or TBW group (0.44 gI/kg of TBW). Abdominal 64-row CT was performed using 120 kVp, 100–200 mAs, rotation time 0.5 s, pitch 1, Iopamidol (370 mgI/mL), and flow rate 3 mL/s. Levene, Mann–Whitney U, and χ2 tests were used. The primary endpoint was liver contrast enhancement (LCE). Results Of 335 enrolled patients, 17 were screening failures; 44 dropped out after randomisation; 274 patients were analysed (133 LBW group, 141 TBW group). The median age of LBW group (66 years) was slightly lower than that of TBW group (70 years). Although the median ICM-injected volume was comparable between groups, its variability was larger in the former (interquartile range 27 mL versus 21 mL, p = 0.01). The same was for unenhanced liver density (IQR 10 versus 7 HU) (p = 0.02). Median LCE was 40 (35–46) HU in the LBW group and 40 (35–44) HU in the TBW group, without significant difference for median (p = 0.41) and variability (p = 0.23). Suboptimal LCE (< 40 HU) was found in 64/133 (48%) patients in the LBW group and 69/141 (49%) in the TBW group, but no examination needed repeating. Conclusions The calculation of the ICM volume to be administered for abdominal CT based on the LBW does not imply a more consistent LCE.

scholarly journals Evaluation of Low-kVp Low-Volume Iodinated Contrast Protocol for Coronary CT Angiography Using Retrospective ECG Gating

2022 ◽  
Author(s):  
Atul Kapoor ◽  
Goldaa Mahajan ◽  
Aprajita Kapoor
Keyword(s):  
Radiation Dose ◽  
Ct Angiography ◽  
Ecg Gating ◽  
Heart Rates ◽  
Iodinated Contrast ◽  
Significant Difference ◽  
Group A ◽  
Low Volume ◽  
Group B ◽  
Low Kvp

Abstract Objective The aim of this study was to evaluate the use of low peak kilovoltage (kVp) low-volume iodinated contrast protocol for performing coronary computed tomography (CT) angiography (CCTA) in patients using retrospective electrocardiogram (ECG) gating. Materials and Methods Hundred prospective patients undergoing CCTA were studied in two groups, A and B, using 70 kilovoltage (kV) and 120 kV protocols with half and standard intravenous volumes of injected iodinated contrast, respectively. All patients had heart rates less than 100 beats/min and body mass index (BMI) less than 31 kg/m2. Both the groups were evaluated for signal-to-noise (S/N) and contrast-to-noise (C/N) ratios along with radiation dose delivered in millisievert (mSv), and for image quality (IQ), on per patient and per segment basis. Results Patients with group A showed statistically reduced radiation dose of 1.86 mSv compared with 6.86 mSv in group B patients. Marked reduction in image noise with statistically improved S/N and C/N ratios in all coronary vessels was seen in group A. S/N ratios in group A were 20.25, 18.68, 19.04, 17.41, and 18.69 for aorta, left main, left anterior descending, right coronary, and left circumflex arteries while they were 13.34, 11.12, 10.96, 9.74, and 8.67 in group B patients. C/N ratios were also higher in all vessels in group A patients, that is, 19.48, 19.48, 19.04, 19.48, and 17.68, compared with group B patients, who had 12.43, 10.03, 9.23, 9.57, and 8.23 ratios (p < 0.0001). No significant difference in IQ per patient and per vessel was seen between both the groups. Discussion Retrospective ECG-gated low-kVp low-volume iodinated contrast protocol provides good diagnostic quality angiograms in patients with BMI up to 31 kg/m2 and with heart rates of less than 100 beats/min with three times reduced radiation dose. The reduced volume of contrast reduces the cost as well as the chance of contrast-induced nephropathy.

Effect of different contrast administration protocols on contrast enhancement and image quality in CT scan

2019 ◽  
Author(s):  
Noor Ruhaya Ibrahim ◽  
Noor Khairiah A. Karim ◽  
Ibrahim Lutfi Shuaib ◽  
Noor Diyana Osman ◽  
Salwah Hashim ◽  
...  
Keyword(s):  
Image Quality ◽  
Contrast Enhancement ◽  
Hounsfield Unit ◽  
Fixed Time ◽  
Qualitative Assessment ◽  
Contrast Administration ◽  
Contrast Volume ◽  
Significant Difference ◽  
Group A ◽  
Group B

Abstract Objective The aim of this study is to compare the effect of different contrast administration protocols practiced in Advanced Medical and Dental Institute, Universiti Sains Malaysia (Group A) and Hospital Pulau Pinang, Malaysia (Group B), on contrast enhancement and image quality in computed tomography scan. The two protocols were fixed time delay (FTD) with fixed volume (FV), and automatic bolus tracking (ABT) with weight based volume (WBV) contrast administration. Quantification of contrast enhancement’s magnitude in four different anatomical structures was measured in Hounsfield Unit (HU) and based on 5-point scale (1=poor, 5=excellent), the images were rated qualitatively.Results Mean enhancement values of all structures in Group B was higher compared to Group A (p = < 0.001). Mean of quality rating between the two groups was statistically not significant (p = 0.185). There was a weak correlation between HU values and administered contrast volume (r = 0.152). It can be concluded that FTD with FV protocol is non inferior to ABT with WBV protocol as it yielded higher degree of contrast enhancement. There was no significant difference between the two protocols in term of qualitative assessment although ABT with WBV protocol had higher mean grading in image quality.

scholarly journals Graft and patient survival in portal vein thrombosis in living donor liver transplantation

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
A M Ramadan ◽  
N M Hytham ◽  
K K Mamdouh ◽  
A M Fathy
Keyword(s):  
Portal Vein ◽  
Portal Vein Thrombosis ◽  
Lower Survival Rate ◽  
Donor Liver Transplantation ◽  
Vein Thrombosis ◽  
Life Saving ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Stay Hospital

Abstract Background and Rational To date, only few studies have evaluated the benefits of anticoagulation in individuals with cirrhosis. An obvious goal of anticoagulation is PV recanalization: when cirrhotic individuals with PVT are treated with anticoagulation, complete recanalization has been described in 33–45% while partial PV recanalization is observed in 15–35% of cases. LDLT has emerged as the alternative life-saving treatment to DDLT. Over the past 2 decades, the number of LDLTs has steadily increased in many transplant centers, especially in Asia. The separation between occlusive and non-occlusive thrombosis is very important; in patients with partial PVT, post-transplant mortality outcomes are no different from non-PVT patients but it is significantly increased in patients with complete PVT. Patients and Methods This randomized prospective study will include 79 patients who will undergo LDLT in Ain Shams Specialized and Egypt Air hospitals, there are two groups of patients according to presence of portal vein thrombosis or not group A 39 patients of non PVT and group B 40 patient of PVT including different grades of PVT according Yerdel classification. Results In this study, there is no significant difference between groups regard age but Males were significantly associated with group B. In this study, there is no significant difference between groups regard CHILD and MELD scores and this findings. In our study there is no significantly difference between groups A and B regarding ICU stay, hospital stay and cell saver. In this study, comparisons of the PVT patients and controls showed no statistical significant differences regard HA thrombosis, post operative pulmonary embolism and biliary leak but PV rethrombosis is significantly associated with PVT patients, mortality sig associated with PVT patients. Conclusion The outcomes of patients with PVT who underwent LDLT are inferior to those without PVT. Patients with PVT has lower survival rate, higher postoperative PV rethrombosis.

scholarly journals EFFECT OF KALO JEERA SEEDS AND PAPAYA LEAF SUPPLEMENTATION ON THE PERFORMANCE OF BROILER

2016 ◽  
Vol 14 (1) ◽  
pp. 37-42 ◽  
Author(s):  
M. G. Sorwar ◽  
M. Mostofa ◽  
M. N. Hasan ◽  
M. Billah ◽  
M. T. Rahman
Keyword(s):  
Body Weight ◽  
Treatment Group ◽  
Nigella Sativa ◽  
Control Group ◽  
Growth Promoter ◽  
Final Body Weight ◽  
Live Body Weight ◽  
Significant Difference ◽  
Group A ◽  
Group B

This experiment was conducted to determine the effect of papaya leaf (Carica papaya) and kalo jeera (Nigella sativa) seeds powdered supplementation in drinking water as a growth promoter in broiler chickens. A total of 20 Cobb-500 broiler chicks (day-old) were purchased from local hatchery (Nourish Poultry and Hatchery Ltd.) and after seven days of acclimatization chicks were randomly divided into two groups, A (n=10) and B (n=10). The group A was kept as a control and not treated. The group B was supplemented with papaya leaf and kalo jeera powder with feed and water. Weekly observations were recorded for live body weight gain up to 5th weeks and hematological tests were performed at 35th day’s age of broiler to search for hematological changes between control (A) and treatment (B) groups. The initial body weight of groups A and B on 1st were 41.00±0.56 gm and 41.50±0.35 gm, respectively and after 35th day of experiment final body weight were 1470±57.35 gm and 1720±58.56 gm, respectively and economics of production were analyzed and found that net profit per broiler was Tk. 8.91 and Tk. 20.69, respectively. The treatment group B was recorded statistically significant (at 1% level) increased (17.00%) for live body weight than that of control group A. The hematological parameters total erythrocyte count (TEC), erythrocyte sedimentation rate (ESR) and hemoglobin (Hb) estimation value of treatment group shows significant difference, while hemoglobin estimation does not show significant difference from control group. The results suggest that better growth performance could be achieved in broilers supplemented with papaya leaf and kalo jeera seeds.

scholarly journals Hiatoplasty with Crura Buttressing versus Hiatoplasty Alone during Laparoscopic Sleeve Gastrectomy

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Andrea Balla ◽  
Silvia Quaresima ◽  
Pietro Ursi ◽  
Ardit Seitaj ◽  
Livia Palmieri ◽  
...  
Keyword(s):  
Sleeve Gastrectomy ◽  
Laparoscopic Sleeve Gastrectomy ◽  
Esophageal Hiatus ◽  
Consecutive Series ◽  
Obese Patients ◽  
Mesh Placement ◽  
Significant Difference ◽  
Group A ◽  
Group B

Introduction. In obese patients with hiatal hernia (HH), laparoscopic sleeve gastrectomy (LSG) with cruroplasty is an option but use of prosthetic mesh crura reinforcement is debated. The aim was to compare the results of hiatal closure with or without mesh buttressing during LSG. Methods. Gastroesophageal reflux disease (GERD) was assessed by the Health-Related Quality of Life (GERD-HRQL) questionnaire before and after surgery in two consecutive series of patients with esophageal hiatus ≤ 4 cm2. After LSG, patients in group A (12) underwent simple cruroplasty, whereas in group B patients (17), absorbable mesh crura buttressing was added. Results. At mean follow-up of 33.2 and 18.1 months for groups A and B, respectively (p=0.006), the mean preoperative GERD-HRQL scores of 16.5 and 17.7 (p=0.837) postoperatively became 9.5 and 2.4 (p=0.071). In group A, there was no difference between pre- and postoperative scores (p=0.279), whereas in group B, a highly significant difference was observed (p=0.002). The difference (Δ) comparing pre- and postoperative mean scores between the two groups was significantly in favor of mesh placement (p=0.0058). Conclusions. In obese patients with HH and mild-moderate GERD, reflux symptoms are significantly improved at medium term follow-up after cruroplasty with versus without crura buttressing during LSG.

scholarly journals Effects of growth promoter and multivitamin-mineral premix supplementation on body weight gain in broiler chickens

2013 ◽  
Vol 10 (2) ◽  
pp. 245-248 ◽  
Author(s):  
MA Rahman ◽  
MS Parvin ◽  
RR Sarker ◽  
MT Islam
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Broiler Chickens ◽  
Body Weight Gain ◽  
The Body ◽  
Growth Promoter ◽  
Commercial Feed ◽  
Significant Difference ◽  
Group A ◽  
Group B

An experiment was conducted at the Khanpura Poultry Farm, near to the Babugonj campus of Patuakhali Science and Technology University, Patuakhali during the period from August to September, 2011 to evaluate the effect of growth promoter and multivitamin-mineral premix on the body weight gain in broiler chickens. A total of 90 ‘Cobb 500’ day-old broiler chickens were randomly divided into three equal groups (n = 30), namely Groups A, B and C. Broiler birds in groups A and B were supplemented with growth promoter and multivitamin-mineral premix, respectively in addition to commercial feed from day 4 till day 25. The dose of both the growth promoter and multivitamin-mineral premix was 2.5 g/kg of feed. Chickens of group C served as control and supplemented with commercial feed only. Body weight was recorded at three times as on day 11, 18 and 25, respectively. The mean body weight was insignificantly (p > 0.05) higher in birds of groups A (992.5±139.6g) and B (978.3±147.0g) than those of group C (926.7±133.2g). The percent increase in body weight gain compare to control was increased in both the supplemented groups (5.8% in group A and 8.8% in group B) though there was no significant difference. Based on the results, it is suggested that supplementation of growth promoter and multivitamin-mineral premix in broilers even after feeding of commercial feed has positive effect on the growth of broilers.DOI: http://dx.doi.org/10.3329/jbau.v10i2.14914 J. Bangladesh Agril. Univ. 10(2): 245-248, 2012

scholarly journals Utilization Of Soymilk As Milk Replacer For Calves

1970 ◽  
Vol 38 (1-2) ◽  
pp. 102-107 ◽  
Author(s):  
AKM Masum ◽  
MN Islam ◽  
MAS Khan
Keyword(s):  
Body Weight ◽  
Body Weight Gain ◽  
Total Body Weight ◽  
Dairy Calves ◽  
Cow Milk ◽  
Milk Replacer ◽  
Significant Difference ◽  
Group A ◽  
Total Body ◽  
Group B

An experiment was conducted to study the utilization of soymilk as milk replacer for raising calves. Nine crossbred calves were selected and divided into three groups on the basis of their body weight and genotype. The calves of group A were reared by cow milk, group B reared by strained soymilk and group C reared by unstrained soymilk. It was found that, total body weight gain of group A, B and C were 13.933 ± 1.222, 13.800 ± 0.917 and 13.233 ± 1.537 Kg, respectively. There was no significant difference among the three groups of calves. Non-significant differences were also seen for increment in wither height (5.588 ± 0.508, 5.419 ± 0.529 and 5.080 ± 0.440 cm, respectively), length (6.096 ± 0.440, 5.927 ± 0.388 and 5.503 ± 0.388 cm, respectively) and heart-girth (5.842 ± 0.440, 5.588 ± 0.916 and 5.419 ± 0.388 cm, respectively) of calves. Economic analysis showed that soymilk was cheaper than cow milk (Tk. 8.0 vs Tk. 44.0). It can be concluded that soymilk as milk replacer could be used successfully for raising dairy calves. DOI: http://dx.doi.org/10.3329/bjas.v38i1-2.9918 BJAS 2009; 38(1-2): 102-107

scholarly journals Prospective randomized trial comparing efficacy and safety of intravenous and intra-articular tranexamic acid in total knee arthroplasty

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Moses Man-Lung Li ◽  
Jojo Yan-Yan Kwok ◽  
Kwong-Yin Chung ◽  
Kin-Wing Cheung ◽  
Kwok-Hing Chiu ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Body Weight ◽  
Blood Transfusion ◽  
Blood Loss ◽  
Efficacy And Safety ◽  
Significant Difference ◽  
Group A ◽  
Total Knee ◽  
Group B ◽  
Adjusted Dose

Abstract Background Total knee arthroplasty (TKA) is associated with significant perioperative blood loss and postoperative allogenic blood transfusion. Tranexamic acid (TXA) reversibly blocks lysine binding sites on plasminogen molecules and inhibits plasmin formation. Comparisons of the efficacy and safety of intra-articular and intravenous TXA in primary TKA have not previously been reported. Methods A prospective randomized trial was conducted in 150 patients who underwent TKA, and these patients were randomized into three groups. Patients in Group A were injected by intra-articular TXA according to body weight (20 mg/kg). Patients in Group B received a standard dose of intra-articular TXA (2000 mg), and those in Group C were infused with TXA according to body weight (20 mg/kg) before tourniquet deflation and again 3 h later. Baseline characteristics and data collected at blood transfusion were compared. Differences among four time points (baseline, day 0, day 2, and day 5) were carried out using ANOVA. Results The hemoglobin levels at postoperative day 5 were 10.6 g/dL for Group A, 10.6 g/dL for Group B, and 10.7 g/dL for Group C. The drain output was 399 ml for Group A, 314 ml for Group B, and 305 ml for Group C (p = 0.03). Group C had significantly less drain output than Group A after post hoc comparisons (p = 0.05), whereas no significant difference was observed between Group A and B (p = 0.09) or between Group B and C. Conclusion The weight-adjusted dose of TXA administered intravenously significantly reduced the drain output but not the total blood loss when compared with the weight-adjusted dose of TXA administered intra-articularly. No significant difference was observed in the other parameters among the three groups. Trial registration The Joint CUHK-NTEC CREC, CRE-2013.644-T. Registered 1 March 2014.

scholarly journals Laparoscopic versus open hysterectomies in obese patients

2018 ◽  
Vol 5 (12) ◽  
pp. 3893
Author(s):  
Soliman A. El Shakhs ◽  
Moharam A. Mohamed ◽  
Mahmoud A. Shahin ◽  
Ahmed M. Eid
Keyword(s):  
Blood Loss ◽  
Surgical Procedure ◽  
Operative Time ◽  
Laparoscopic Hysterectomy ◽  
Obese Patients ◽  
Optimal Route ◽  
Significant Difference ◽  
Group A ◽  
Prospective Comparative Study ◽  
Group B

Background: Hysterectomy is one of the most frequently performed surgical procedure. Though there are three approaches in hysterectomy (open, vaginal and laparoscopic), still there are controversies regarding the optimal route for performing it.Methods: This prospective comparative study included 42 obese patients subjected for pan-hysterectomy as a treatment. The forty-two patients were allocated into two groups: group (A) subjected to laparoscopic pan-hysterectomy, group (B) subjected to open pan-hysterectomy.Results: There was significant difference between the two groups regarding mean operative time, blood loss, analgesic requirements and hospital stay, while no significant difference regarding intra-operative complications.Conclusions: Laparoscopic hysterectomy in obese patients has emerged as a viable, safe and better alternative to open hysterectomy amongst appropriately trained surgeons.

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