Oral Submucous Fibrosis in Pediatric Patients: A Systematic Review and Protocol for Management

Aim. To conduct a systematic review evaluating the cases of oral submucous fibrosis in pediatric patients. Material and Method. Systematic review was conducted using PRISMA guidelines. The article focused on oral submucous fibrosis in pediatric patients were included. A total of five manuscripts were included in our systematic review. The prevalence of OSMF in pediatric patients, gender distribution, causes, and clinical presentation were reviewed. Results. On systematically reviewing, a total of 10 cases of OSMF in pediatric patients were found. The youngest patient reported to be diagnosed with OSMF was of 2.5 years of age. Female preponderance was noticed. All the patients had the habit of areca nut chewing which subsequently led to fibrosis. Conclusion. Such a rapid increase in the rate of OSMF among pediatric population is a potential danger to the society. The habit of areca nut chewing is the major cause for this dreadful condition. Lack of health consciousness and low level of education are the major factors for initiation of this habit among children. Therefore it is imperative for the parents and school as well as government authorities to take serious actions.

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Oral Submucous Fibrosis and Its Relation with Stromal Vascularity: A Systematic Review

European Journal of Medical and Health Sciences ◽

10.24018/ejmed.2020.2.2.162 ◽

2020 ◽

Vol 2 (2) ◽

Author(s):

Sayed Nishat Abdul

Keyword(s):

Systematic Review ◽

Connective Tissue ◽

Southeast Asia ◽

Indian Subcontinent ◽

Oral Submucous Fibrosis ◽

Systemic Review ◽

Esophageal Mucosa ◽

Areca Nut ◽

Commercial Preparation ◽

Submucous Fibrosis

Oral submucous fibrosis (OSMF) is a chronic progressive, scarring disease affecting oral, oropharyngeal, and sometimes the esophageal mucosa. It is characterized by the progressive fibrosis of the submucosal tissue. The pathogenesis of OSMF has been directly related to the habit of chewing areca nut and its commercial preparation, which is widespread in Indian subcontinent and Southeast Asia. Malignant transformation has been reported in 7%–12% cases of OSMF. Histopathological spectrum of OSMF includes the apparent alterations observed in the epithelium and connective tissue. Vascularity in OSMF has always been a matter of debate. The prevailing concept is that epithelial atrophy occurs due to lack of perfusion. The present systemic review was done to evaluate oral submucous fibrosis and its relation with stromal vascularity.

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Patient-reported outcome measures for pediatric patients with sport-related injuries: a systematic review

Journal of Athletic Training ◽

10.4085/1062-6050-0598.20 ◽

2021 ◽

Author(s):

Ashley N. Marshall ◽

Hayley J. Root ◽

Tamara C. Valovich McLeod ◽

Kenneth C. Lam

Keyword(s):

Systematic Review ◽

Psychometric Properties ◽

Outcome Measures ◽

Clinical Utility ◽

Pediatric Patients ◽

Pediatric Population ◽

Patient Reported Outcome Measures ◽

Patient Reported Outcome ◽

Measurement Properties ◽

Patient Reported

ABSTRACT Despite a call to incorporate PROMs into all aspects of health care, little is known about which instruments are best-suited for a pediatric patient population with sport-related injury. The objective of this article was to perform a systematic review of the currently available evidence to determine which patient-reported outcome measures (PROMs) are used for pediatric patients with sports-related injuries, and to identify the associated psychometric properties and considerations for clinical utility. We conducted a literature search for articles on PROMs used in the pediatric population through electronic databases and via a manual search of reference lists and authors between 1990 and 2020. Articles were grouped based off of the PROM(s) included, and considerations for clinical utility and psychometric properties were extracted from each article. Thirty-nine articles were included in this review, from which twenty-two PROMs were identified - twelve PROMs were developed specifically for the pediatric population, four were modified versions of an adult scale, and six instruments were adult measures used in a pediatric population. Of the PROMs included in this review, the Oxford Ankle Foot Questionnaire for Children (OxAFQ-C) and the Pediatric Quality of Life Inventory (PedsQL) were the most comprehensive in their development and assessment. Several outcome measures used for pediatric patients had missing or inadequate measurement properties and considerations for clinical utility, particularly in regards to readability, responsiveness and interpretability. Clinicians and researchers should consider the measure's feasibility, acceptability, appropriateness and psychometric psychometric properties when selecting a PROM for use with the pediatric population.

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A Systematic Review of Characteristics Associated with COVID-19 in Children with Typical Presentation and with Multisystem Inflammatory Syndrome

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18168269 ◽

2021 ◽

Vol 18 (16) ◽

pp. 8269

Author(s):

Jeffrey Kornitzer ◽

Jacklyn Johnson ◽

Max Yang ◽

Keith W. Pecor ◽

Nicholas Cohen ◽

...

Keyword(s):

Systematic Review ◽

Sore Throat ◽

Literature Search ◽

Clinical Presentation ◽

Pediatric Population ◽

Chinese Language ◽

Clinical Information ◽

Shortness Of Breath ◽

Global Pandemic ◽

Inflammatory Syndrome

Setting off a global pandemic, coronavirus disease 2019 (COVID-19) has been marked by a heterogeneous clinical presentation that runs the gamut from asymptomatic to severe and fatal. Although less lethal in children than adults, COVID-19 has nonetheless afflicted the pediatric population. This systematic review used clinical information from published literature to assess the spectrum of COVID-19 presentation in children, with special emphasis on characteristics associated with multisystem inflammatory syndrome (MIS-C). An electronic literature search for English and Chinese language articles in COVIDSeer, MEDLINE, and PubMed from 1 January 2020 through 1 March 2021 returned 579 records, of which 54 were included for full evaluation. Out of the total 4811 patients, 543 (11.29%) exhibited MIS-C. The most common symptoms across all children were fever and sore throat. Children presenting with MIS-C were less likely to exhibit sore throat and respiratory symptoms (i.e., cough, shortness of breath) compared to children without MIS-C. Inflammatory (e.g., rash, fever, and weakness) and gastrointestinal (e.g., nausea/vomiting and diarrhea) symptoms were present to a greater extent in children with both COVID-19 and MIS-C, suggesting that children testing positive for COVID-19 and exhibiting such symptoms should be evaluated for MIS-C.

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To Study the Prevalence of Areca Nut Induced Oral Submucous Fibrosis in Patients Visiting Dental OPD of Shalinitai Meghe Hospital and Research Center Nagpur: A Demographic Study

Indian Journal of Forensic Medicine & Toxicology ◽

10.37506/ijfmt.v14i4.12597 ◽

2020 ◽

Keyword(s):

Oral Submucous Fibrosis ◽

Research Center ◽

Areca Nut ◽

Demographic Study ◽

Submucous Fibrosis

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Laser as a promising non-invasive technique to treat oral submucous fibrosis: A systematic review of the literature

The Saudi Dental Journal ◽

10.1016/j.sdentj.2020.11.005 ◽

2020 ◽

Author(s):

Sonia Gupta ◽

Manveen Kaur Jawanda

Keyword(s):

Systematic Review ◽

Oral Submucous Fibrosis ◽

Invasive Technique ◽

Review Of The Literature ◽

Non Invasive ◽

Submucous Fibrosis

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Reasons for Initiation of Areca Nut and Related Products in Patients with Oral Submucous Fibrosis within an Endemic Area in Gujarat, India

Substance Use & Misuse ◽

10.1080/10826084.2019.1660678 ◽

2020 ◽

Vol 55 (9) ◽

pp. 1413-1421 ◽

Cited By ~ 8

Author(s):

Chandramani B. More ◽

Naman Rajeshkumar Rao ◽

Sucheta More ◽

Newell W. Johnson

Keyword(s):

Endemic Area ◽

Oral Submucous Fibrosis ◽

Areca Nut ◽

Submucous Fibrosis

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Hearing Efficiency in Oral Submucous Fibrosis: A Clinical Study

Indian Journal of Otolaryngology and Head & Neck Surgery ◽

10.1007/s12070-020-02246-5 ◽

2020 ◽

Author(s):

J. S. Shah ◽

Nutan Lunagariya

Keyword(s):

Oral Mucosa ◽

Conductive Hearing Loss ◽

Oral Submucous Fibrosis ◽

Hearing Threshold ◽

Mouth Opening ◽

Burning Sensation ◽

Areca Nut ◽

Gradual Reduction ◽

Submucous Fibrosis ◽

Conductive Hearing

Abstract Oral Submucous fibrosis (OSMF) is a chronic insidious disease of oral mucosa that occurs due to areca-nut chewing, consumption of chillies, autoimmunity and genetic predisposition. The disease starts with burning sensation and inability to tolerate spicy foods with gradual reduction in mouth opening due to fibrosis of the oral mucosa. The extension of fibrosis into the naso pharynx leads to reduction in hearing efficiency. As very few studies had been done to evaluate the hearing disability in OSMF patients, this study had been undertaken to prove the same. To evaluate hearing efficiency in patients with Oral Submucous Fibrosis of various grades of severity. Presentation includes 30 patients of osmf with various grades and evaluated for hearing efficacy by audiometry. Hearing threshold was compared in different grades of osmf. The present study revealed a significant association between OSMF and hearing deficit. Involvement of the palatal muscles with OSMF may decrease the patency of the Eustachian tube, leading to conductive hearing loss. Therefore, the protocol for managing OSMF patients should include ENT consultation and treatment for hearing deficit in order to increase the success rate of treatment.

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