The processing of denture base resins may originate dimensional changes that can alter the occlusal position of artificial teeth of the concluded prosthesis. The polymerization method and the water sorption property of the acrylic resin may cause these changes. Pressure, temperature, and time of water sorption may also have influence on the previous alterations. The aim of this research was to verify the alteration of buccal cusps position of first molars on marillary dentures, polymerized by water bath (9 hours at 76ºC) and microwave energy (3 min at 500W), regarding water sorption under different conditions of time, pressure, and temperature of water storage. Sixty dentures were waxed onto metal die simulating an edentulous maxilla and divided into 4 groups (GI, GII, GIII, and GIV) of 15 samples each. Four different treatments, as follows, were applied to these samples: processing by water bath and stored in water under environmental pressure for 30 days at 37±2ºC (control -GI); processing by water bath and stored in water under 40 pounds for 1 hour at 60±2ºC (Gll): processing br microrwawe energy and stored in water under environmental pressure for 30 days at 37±2ºC(GIII): and processing by microware enerrgy and stored in water under 40 pounds for 1 hour at 60±2ºC (GIV). The degree diferences obtained between the pre and post water sorption were 0.65 for GI; 0.55 for GII; 0.83 for GIII, and -0.57 for GIV (p>0.05). There was significant alteration in the positioning of the artificial firth maxillary molars among the control and the treated storage groups, when cured by microwave energy or water bath.