A NEUROPHYSIOLOGY-BASED MODEL TO ESTIMATE VISIBILITY IN ACTUAL LIGHTING ENVIRONMENT

Visibility is one of the fundamental factors for explaining the lighting environment, and various quantitative indexes for these have been made in such a manner that directly finds the formulae that best match the numerous subjective evaluations. Recently neurophysiology-based models have been paid attention as the complementary or alternative methods to these conventional indexes. In this paper we will introduce the normalization and gain control models, which are generally accepted theories in the visual information processing, to estimate the visibility, and verify the validity of this algorithm by comparing with the subjective evaluation in the experimental room. The result showed that the algorithm in this research could estimate the visibility of the simple objects in the experimental space with a pseudo window with great accuracy, however, it is desirable and necessary to publicly discuss various algorithms and clarify their reliability based on the verification results under various situations.

Intelligent numerical computation method and quantitative study on morphological characteristics of multi-scale aggregate

Use Image-Pro Plus software, high-precision inductive sensor TR200, electro n microscope and ENVI image processing system to quantitatively study aggregate mo rphology from three scales: macro, meso, and micro, and obtain P, As, R, Ry, Rsm, et c. 17 quantitative indicators of morphological characteristics, compared with the occup ancy rate of the aggregate broken surface and the roughness of the aggregate surface. T he results show that the 17 morphological characteristics indexes are feasible for multi -scale quantification of aggregate morphology. Macro-morphological characteristics di rectly indicate the angularity and needle-like shape of materials, micro-morphological characteristics directly indicate the roughness of materials surface, and micro-morphol ogical characteristics directly indicate the micro-morphological characteristics of mate rials. The quantitative indexes of aggregate morphology at micro-scale and micro-scal e are improved, and the results are helpful to reveal the morphological characteristics o f aggregate comprehensively.

Total Lung and Lobar Quantitative Assessment Based on Paired Inspiratory–Expiratory Chest CT in Healthy Adults: Correlation with Pulmonary Ventilatory Function

Objective: To provide the quantitative volumetric data of the total lung and lobes in inspiration and expiration from healthy adults, and to explore the value of paired inspiratory–expiratory chest CT scan in pulmonary ventilatory function and further explore the influence of each lobe on ventilation. Methods: A total of 65 adults (29 males and 36 females) with normal clinical pulmonary function test (PFT) and paired inspiratory–expiratory chest CT scan were retrospectively enrolled. The inspiratory and expiratory volumetric indexes of the total lung (TL) and 5 lobes (left upper lobe [LUL], left lower lobe [LLL], right upper lobe [RUL], right middle lobe [RML], and right lower lobe [RLL]) were obtained by Philips IntelliSpace Portal image postprocessing workstation, including inspiratory lung volume (LVin), expiratory lung volume (LVex), volume change (∆LV), and well-aerated lung volume (WAL, lung tissue with CT threshold between −950 and -750HU in inspiratory scan). Spearman correlation analysis was used to explore the correlation between CT quantitative indexes of the total lung and ventilatory function indexes (including total lung capacity [TLC], residual volume [RV], and force vital capacity [FVC]). Multiple stepwise regression analysis was used to explore the influence of each lobe on ventilation. Results: At end-inspiratory phase, the LVin-TL was 4664.6 (4282.7, 5916.2) mL, the WALTL was 4173 (3639.6, 5250.9) mL; both showed excellent correlation with TLC (LVin-TL: r = 0.890, p < 0.001; WALTL: r = 0.879, p < 0.001). From multiple linear regression analysis with lobar CT indexes as variables, the LVin and WAL of these two lobes, LLL and RUL, showed a significant relationship with TLC. At end-expiratory phase, the LVex-TL was 2325.2 (1969.7, 2722.5) mL with good correlation with RV (r = 0.811, p < 0.001), of which the LVex of RUL and RML had a significant relationship with RV. For the volumetric change within breathing, the ∆LVTL was 2485.6 (2169.8, 3078.1) mL with good correlation with FVC (r = 0.719, p < 0.001), moreover, WALTL showed a better correlation with FVC (r = 0.817, p < 0.001) than that of ∆LVTL. Likewise, there was also a strong association between ∆LV, WAL of these two lobes (LLL and RUL), and FVC. Conclusions: The quantitative indexes derived from paired inspiratory–expiratory chest CT could reflect the clinical pulmonary ventilatory function, LLL, and RUL give greater impact on ventilation. Thus, the pulmonary functional evaluation needs to be more precise and not limited to the total lung level.

Evaluation of the development ability of medical association based on evidential reasoning and prospect theory

China has proposed medical couplet body to alleviate residents’ difficulties in seeking medical treatment, and the future development ability of medical couplet body has gradually become a research interest. On the basis of prospect theory, this study constructs a comprehensive evaluation index system with qualitative and quantitative indexes, clear hierarchy, and diverse attribute characteristics. The development ability of medical couplet body is also comprehensively and systematically evaluated. In addition, the evidential reasoning method is proposed on the basis of the equivalent transformation of prospect value. Furthermore, the validity and feasibility of the model are proven through experiments, and the influence of decision makers’ risk attitude on the evaluation results is discussed.

A single transcript for the prognosis of disease severity in COVID-19 patients

With many countries strapped for medical resources due to the COVID-19 pandemic, it is highly desirable to allocate the precious resources to those who need them the most. Several markers have been found to be associated with the disease severity in COVID-19 patients. However, the established markers only display modest prognostic power individually and better markers are urgently needed. The aim of this study is to investigate the potential of S100A12, a prominent marker gene for bacterial infection, in the prognosis of disease severity in COVID-19 patients. To ensure the robustness of the association, a total of 1695 samples from 14 independent transcriptome datasets on sepsis, influenza infection and COVID-19 infection were examined. First, it was demonstrated that S100A12 was a marker for sepsis and severity of sepsis. Then, S100A12 was found to be a marker for severe influenza infection, and there was an upward trend of S100A12 expression as the severity level of influenza infection increased. As for COVID-19 infection, it was found that S100A12 expression was elevated in patients with severe and critical COVID-19 infection. More importantly, S100A12 expression at hospital admission was robustly correlated with future quantitative indexes of disease severity and outcome in COVID-19 patients, superior to established prognostic markers including CRP, PCT, d-dimer, ferritin, LDH and fibrinogen. Thus, S100A12 is a valuable novel prognostic marker for COVID-19 severity and deserves more attention.

Evaluation of sustainability of agricultural systems of indigenous people in Hidalgo, Mexico

Agricultural sustainability depends on complex relationships between environmental, economic and social aspects, in particular with the small farmholders from indigenous communities. This work was centred in two municipalities of Hidalgo State in Mexico, Ixmiquilpan (mainly irrigated systems) and El Cardonal (rainfed systems). Our objective was to understand the relationships between the small farm-holders and their agricultural systems, evaluating their sustainability and design strategies and pathways for the sustainable development for indigenous communities. For this, we applied the Framework for the Evaluation of Management Systems using Indicators (MESMIS, Spanish acronym). Thirty one indicators were identified and quantitative indexes were established to be used to assess sustainability. The results showed that adaptability was a critical factor for both systems, and the main problem identified was youth migration. Additionally, the access to water and economic resources, as well as management of environmental resources, are imperious needs to increase the yield of agriculture crops. Therefore, integral strategies need to take into account the organization of small producers and the combination of indigenous and modern technologies, to design technologies for the territorial development of the communities.

An Ensemble Hybrid forecasting Model for Annual Runoff Based on Sample Entropy, Secondary Decomposition, and Long Short-Term Memory Neural Network

Accurate and consistent annual runoff prediction in regions is a hot topic in the management, optimization, and monitoring of water resources. A novel prediction model (ESMD-SE-WPD-LSTM) is presented in this study. Firstly, the extreme-point symmetric mode decomposition (ESMD) is used to produce several intrinsic mode functions (IMF) and a residual (Res) by decomposing the original runoff series. Secondly, the sample entropy (SE) method is employed to measure the complexity of each IMF. Thirdly, we adopt wavelet packet decomposition (WPD) to further decompose the IMF with the maximum SE into several appropriate components and detailed components. Then the LSTM model, a deep learning algorithm based recurrent approach, is employed to predict all components obtained in the previous step. Finally, the forecasting results of all components are aggregated to generate the final prediction. The proposed model, which is applied to five annual series from different areas in China, is evaluated based on four quantitative indexes (R, NSEC, MAPE and RMSE). The results indicate that the ESMD-SE-WPD-LSTM outperforms other benchmark models in terms of four quantitative indexes. Hence the proposed model can provide higher accuracy and consistency for annual runoff prediction, making it an efficient instrument for scientific management and planning of water resources.

Quantitative and Qualitative Running Gait Analysis through an Innovative Video-Based Approach

Quantitative and qualitative running gait analysis allows the early identification and the longitudinal monitoring of gait abnormalities linked to running-related injuries. A promising calibration- and marker-less video sensor-based technology (i.e., Graal), recently validated for walking gait, may also offer a time- and cost-efficient alternative to the gold-standard methods for running. This study aim was to ascertain the validity of an improved version of Graal for quantitative and qualitative analysis of running. In 33 healthy recreational runners (mean age 41 years), treadmill running at self-selected submaximal speed was simultaneously evaluated by a validated photosensor system (i.e., Optogait—the reference methodology) and by the video analysis of a posterior 30-fps video of the runner through the optimized version of Graal. Graal is video analysis software that provides a spectral analysis of the brightness over time for each pixel of the video, in order to identify its frequency contents. The two main frequencies of variation of the pixel’s brightness (i.e., F1 and F2) correspond to the two most important frequencies of gait (i.e., stride frequency and cadence). The Optogait system recorded step length, cadence, and its variability (vCAD, a traditional index of gait quality). Graal provided a direct measurement of F2 (reflecting cadence), an indirect measure of step length, and two indexes of global gait quality (harmony and synchrony index). The correspondence between quantitative indexes (Cadence vs. F2 and step length vs. Graal step length) was tested via paired t-test, correlations, and Bland–Altman plots. The relationship between qualitative indexes (vCAD vs. Harmony and Synchrony Index) was investigated by correlation analysis. Cadence and step length were, respectively, not significantly different from and highly correlated with F2 (1.41 Hz ± 0.09 Hz vs. 1.42 Hz ± 0.08 Hz, p = 0.25, r2 = 0.81) and Graal step length (104.70 cm ± 013.27 cm vs. 107.56 cm ± 13.67 cm, p = 0.55, r2 = 0.98). Bland–Altman tests confirmed a non-significant bias and small imprecision between methods for both parameters. The vCAD was 1.84% ± 0.66%, and it was significantly correlated with neither the Harmony nor the Synchrony Index (0.21 ± 0.03, p = 0.92, r2 = 0.00038; 0.21 ± 0.96, p = 0.87, r2 = 0.00122). These findings confirm the validity of the optimized version of Graal for the measurement of quantitative indexes of gait. Hence, Graal constitutes an extremely time- and cost-efficient tool suitable for quantitative analysis of running. However, its validity for qualitative running gait analysis remains inconclusive and will require further evaluation in a wider range of absolute and relative running intensities in different individuals.