scholarly journals Synovial Macrophages in Rheumatoid Arthritis: The Past, Present, and Future

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Jiajie Tu ◽  
Xinming Wang ◽  
Xun Gong ◽  
Wenming Hong ◽  
Dafei Han ◽  
...  

The ontogeny of macrophages in most organs has already been established. Owing to the limited number and inaccessibility of synovial macrophages (SMs), the origin of SMs has not been fully elucidated. Previous studies suggested that SMs have two major origins, namely, tissue-resident and monocyte-derived SMs. However, no systematic analysis to identify SM ontology in either physiological or pathological conditions has been available to date. In this review, we summarize relevant studies on the two main origins of SMs in rheumatoid arthritis (RA) and forecast the future research directions for this field. Furthermore, we discuss the current state of RA therapy that is based on targeting different SM subsets.

2020 ◽  
Vol 27 (10) ◽  
pp. 3309-3339
Author(s):  
Yan-Chun Zhang ◽  
Wu-Zan Luo ◽  
Ming Shan ◽  
Dong-Wen Pan ◽  
Wen-Jie Mu

PurposeThe aims of this study are to conduct a systematic review of public–private partnership (PPP) studies published from 2009 to 2019, to compare the results with Ke et al. (2009) who reviewed the PPP literature published from 1998 to 2008, and to trace the evolution of the PPP knowledge in the past two decades. This study also presents the possible directions that the PPP research may go towards in the future, arguably.Design/methodology/approachThis study carried out a top journal-based search to identify the quality PPP articles published from 2009 to 2019. A total of 12 top-tier construction journals were systematically searched in the database of web of science (WOS), from which 279 PPP articles were identified for review.FindingsThe number of the identified articles, the titles of the journals, institutions, the most cited papers, and prevalent research methods were analyzed and compared. The existing PPP studies in construction journals were classified into seven streams. Through analysis of the PPP research status and gaps, five future research directions were revealed.Originality/valueThis study contributes to the current body of knowledge by revealing the research trend of PPP from 2009 to 2019. It presents the change of PPP development trend in the past decade through comparison with Ke et al. (2009). It also reveals the major research streams and points out the directions that the PPP research may go towards in the future. Moreover, this study is helpful to the practice as well. It can enhance the practitioners' understanding of the PPP development in the past decade. In addition, it identified the research institutions contributing the most in the area of PPP, which may serve as valuable reference for practitioners to locate the best institutions for consultancy or collaboration.


Author(s):  
Candida G. Brush

Despite the proliferation of research, the population of women entrepreneurs is vastly understudied. This is surprising considering women are one of the fastest rising populations of entrepreneurs, and contribute significantly to innovation, job creation, and economies around the world. Why are women entrepreneurs comparatively understudied? What have we learned about women entrepreneurs in the past few decades? What are the future research directions? This article addresses these questions. It begins with a brief overview on the extent of research on women's entrepreneurship and considers reasons why they are under-studied. The article also explores empirical findings in terms of similarities and differences between men and women entrepreneurs, then it concludes with suggestions for future research.


2012 ◽  
pp. 847-854
Author(s):  
Catherine D. Marcum ◽  
George E. Higgins

This entry provides an examination of the past and present prevalence and issues surrounding online child pornography in the United States. Legal definitions of child pornography are explained, followed by an analysis of the current empirical knowledge on the topic, as well as the legal and legislative history. Finally, a brief discussion of the future research directions on the topic will be discussed.


Author(s):  
Taiwo Oseni ◽  
Susan Valerie Foster ◽  
Rahim Mahbubur ◽  
Stephen Patrick Smith

Post-implementation amendments to ERP systems (ERP-PIA) are of importance for advancing ERP research, but more importantly essential if ERP systems are to be used as a strategic and competitive business tool. For ease of clarity, we have adopted the term “amendments” to encompass the main forms of post implementation activities: maintenance, enhancements and upgrades. The term ‘amendments’ is used to counteract one of the major findings from this research - the inconsistency of terms used by many authors to explain post implementation activities. This paper presents a review of the ERP post-implementation amendment literature in order to provide answers to two specific questions: first, what is the current state of research in the field of ERP-PIA; and second, what are the future research directions that need to be explored in the field of ERP-PIA. From the review, we develop a framework to identify: (a) major themes concerning ERP post-implementation amendments, (b) inherent gaps in the post-implementation amendments literature, and (c) specific areas that require further research attention influencing the uptake of amendments. Suggestions on empirical evaluation of research directions and their relevance in the extension of existing literature is presented.


2019 ◽  
Vol 16 (3) ◽  
pp. 6-14
Author(s):  
Murali Suhas ◽  
Srikanteshwara Parveen-Kumar

Systemic Lupus Erythematosus is a long-studied condition with protean manifestations, yet, with so much known about the pathogenesis and treatment aspects still in the dark. In this review article, we try to sum up all the knowledge we have till date, the practice essentials used to date and the future research directions, all of which ultimately lead to a better understanding of the disease and its management.


Author(s):  
Xiaochen Zhang ◽  
Lanxin Hui ◽  
Linchao Wei ◽  
Fuchuan Song ◽  
Fei Hu

Electric power wheelchairs (EPWs) enhance the mobility capability of the elderly and the disabled, while the human-machine interaction (HMI) determines how well the human intention will be precisely delivered and how human-machine system cooperation will be efficiently conducted. A bibliometric quantitative analysis of 1154 publications related to this research field, published between 1998 and 2020, was conducted. We identified the development status, contributors, hot topics, and potential future research directions of this field. We believe that the combination of intelligence and humanization of an EPW HMI system based on human-machine collaboration is an emerging trend in EPW HMI methodology research. Particular attention should be paid to evaluating the applicability and benefits of the EPW HMI methodology for the users, as well as how much it contributes to society. This study offers researchers a comprehensive understanding of EPW HMI studies in the past 22 years and latest trends from the evolutionary footprints and forward-thinking insights regarding future research.


2021 ◽  
Vol 108 ◽  
pp. 103309
Author(s):  
Tatiane Tobias da Cruz ◽  
José A. Perrella Balestieri ◽  
João M. de Toledo Silva ◽  
Mateus R.N. Vilanova ◽  
Otávio J. Oliveira ◽  
...  

2017 ◽  
Vol 119 (1) ◽  
pp. 1-6
Author(s):  
Adrienne D. Dixson ◽  
Gloria Ladson-Billings

The articles in this special issue represent both our attempt as editors to survey the field and provide some clarity for practitioners and teacher educators on fundamental ideas that frame CRP, not to limit its implementation or future research directions, but to ensure that as a community of educators and scholars, we share a common understanding of exactly what it means to be culturally relevant. The articles in this special issue provide both that clarity of the field, and vision for the future.


Author(s):  
Alauddin Yousif Al-Omary

In this chapter, the benefit of equipping the robot with odor sensors is investigated. The chapter addresses the types of tasks the mobile robots can accomplish with the help of olfactory sensing capabilities, the technical challenges in mobile robot olfaction, the status of mobile robot olfaction. The chapter also addresses simple and complex electronic olfaction sensors used in mobile robotics, the challenge of using chemical sensors, the use of many types of algorithms for robot olfaction, and the future research directions in the field of mobile robot olfaction.


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