scholarly journals A Semantic Analysis and Community Detection-Based Artificial Intelligence Model for Core Herb Discovery from the Literature: Taking Chronic Glomerulonephritis Treatment as a Case Study

2020 ◽  
Vol 2020 ◽  
pp. 1-23
Author(s):  
Yun Zhang ◽  
Yongguo Liu ◽  
Jiajing Zhu ◽  
Shuangqing Zhai ◽  
Rongjiang Jin ◽  
...  

The Traditional Chinese Medicine (TCM) formula is the main treatment method of TCM. A formula often contains multiple herbs where core herbs play a critical therapeutic effect for treating diseases. It is of great significance to find out the core herbs in formulae for providing evidences and references for the clinical application of Chinese herbs and formulae. In this paper, we propose a core herb discovery model CHDSC based on semantic analysis and community detection to discover the core herbs for treating a certain disease from large-scale literature, which includes three stages: corpus construction, herb network establishment, and core herb discovery. In CHDSC, two artificial intelligence modules are used, where the Chinese word embedding algorithm ESSP2VEC is designed to analyse the semantics of herbs in Chinese literature based on the stroke, structure, and pinyin features of Chinese characters, and the label propagation-based algorithm LILPA is adopted to detect herb communities and core herbs in the herbal semantic network constructed from large-scale literature. To validate the proposed model, we choose chronic glomerulonephritis (CGN) as an example, search 1126 articles about how to treat CGN in TCM from the China National Knowledge Infrastructure (CNKI), and apply CHDSC to analyse the collected literature. Experimental results reveal that CHDSC discovers three major herb communities and eighteen core herbs for treating different CGN syndromes with high accuracy. The community size, degree, and closeness centrality distributions of the herb network are analysed to mine the laws of core herbs. As a result, we can observe that core herbs mainly exist in the communities with more than 25 herbs. The degree and closeness centrality of core herb nodes concentrate on the range of [15, 40] and [0.25, 0.45], respectively. Thus, semantic analysis and community detection are helpful for mining effective core herbs for treating a certain disease from large-scale literature.

2021 ◽  
Vol 2021 ◽  
pp. 1-18
Author(s):  
Yun Zhang ◽  
Yongguo Liu ◽  
Jiajing Zhu ◽  
Zhi Chen ◽  
Dongxiao Li ◽  
...  

Cold pathogenic disease is a widespread disease in traditional Chinese medicine, which includes influenza and respiratory infection associated with high incidence and mortality. Discovering effective core drugs in Chinese medicine prescriptions for treating the disease and reducing patients’ symptoms has attracted great interest. In this paper, we explore the core drugs for curing various syndromes of cold pathogenic disease from large-scale literature. We propose a core drug discovery framework incorporating word embedding and community detection algorithms, which contains three parts: disease corpus construction, drug network generation, and core drug discovery. First, disease corpus is established by collecting and preprocessing large-scale literature about the Chinese medicine treatment of cold pathogenic disease from China National Knowledge Infrastructure. Second, we adopt the Chinese word embedding model SSP2VEC for mining the drug implication implied in the literature; then, a drug network is established by the semantic similarity among drugs. Third, the community detection method COPRA based on label propagation is adopted to reveal drug communities and identify core drugs in the drug network. We compute the community size, closeness centrality, and degree distributions of the drug network to analyse the patterns of core drugs. We acquire 4681 literature from China national knowledge infrastructure. Twelve significant drug communities are discovered, in which the top-10 drugs in every drug community are recognized as core drugs with high accuracy, and four classical prescriptions for treating different syndromes of cold pathogenic disease are discovered. The proposed framework can identify effective core drugs for curing cold pathogenic disease, and the research can help doctors to verify the compatibility laws of Chinese medicine prescriptions.


2020 ◽  
Vol 34 (10) ◽  
pp. 13849-13850
Author(s):  
Donghyeon Lee ◽  
Man-Je Kim ◽  
Chang Wook Ahn

In a real-time strategy (RTS) game, StarCraft II, players need to know the consequences before making a decision in combat. We propose a combat outcome predictor which utilizes terrain information as well as squad information. For training the model, we generated a StarCraft II combat dataset by simulating diverse and large-scale combat situations. The overall accuracy of our model was 89.7%. Our predictor can be integrated into the artificial intelligence agent for RTS games as a short-term decision-making module.


Author(s):  
Serhad Sarica ◽  
Binyang Song ◽  
Jianxi Luo ◽  
Kristin L. Wood

Abstract There are growing efforts to mine public and common-sense semantic network databases for engineering design ideation stimuli. However, there is still a lack of design ideation aids based on semantic network databases that are specialized in engineering or technology-based knowledge. In this study, we present a new methodology of using the Technology Semantic Network (TechNet) to stimulate idea generation in engineering design. The core of the methodology is to guide the inference of new technical concepts in the white space surrounding a focal design domain according to their semantic distance in the large TechNet, for potential syntheses into new design ideas. We demonstrate the effectiveness in general, and use strategies and ideation outcome implications of the methodology via a case study of flying car design idea generation.


2021 ◽  
Vol 15 (6) ◽  
pp. 1-20
Author(s):  
Zhe Chen ◽  
Aixin Sun ◽  
Xiaokui Xiao

Community detection on network data is a fundamental task, and has many applications in industry. Network data in industry can be very large, with incomplete and complex attributes, and more importantly, growing. This calls for a community detection technique that is able to handle both attribute and topological information on large scale networks, and also is incremental. In this article, we propose inc-AGGMMR, an incremental community detection framework that is able to effectively address the challenges that come from scalability, mixed attributes, incomplete values, and evolving of the network. Through construction of augmented graph, we map attributes into the network by introducing attribute centers and belongingness edges. The communities are then detected by modularity maximization. During this process, we adjust the weights of belongingness edges to balance the contribution between attribute and topological information to the detection of communities. The weight adjustment mechanism enables incremental updates of community membership of all vertices. We evaluate inc-AGGMMR on five benchmark datasets against eight strong baselines. We also provide a case study to incrementally detect communities on a PayPal payment network which contains users with transactions. The results demonstrate inc-AGGMMR’s effectiveness and practicability.


2021 ◽  
Vol 65 (8) ◽  
pp. 51-60
Author(s):  
Yujeong Kim

Today, each country has interest in digital economy and has established and implemented policies aimed at digital technology development and digital transformation for the transition to the digital economy. In particular, interest in digital technologies such as big data, 5G, and artificial intelligence, which are recognized as important factors in the digital economy, has been increasing recently, and it is a time when the role of the government for technological development and international cooperation becomes important. In addition to the overall digital economic policy, the Russian and Korean governments are also trying to improve their international competitiveness and take a leading position in the new economic order by establishing related technical and industrial policies. Moreover, Republic of Korea often refers to data, network and artificial intelligence as D∙N∙A, and has established policies in each of these areas in 2019. Russia is also establishing and implementing policies in the same field in 2019. Therefore, it is timely to find ways to expand cooperation between Russia and Republic of Korea. In particular, the years of 2020and 2021marks the 30th anniversary of diplomatic relations between the two countries, and not only large-scale events and exchange programs have prepared, but the relationship is deepening as part of the continued foreign policy of both countries – Russia’s Eastern Policy and New Northern Policy of Republic of Korea. Therefore, this paper compares and analyzes the policies of the two countries in big data, 5G, and artificial intelligence to seek long-term sustainable cooperation in the digital economy.


2017 ◽  
Vol 139 (11) ◽  
Author(s):  
Feng Shi ◽  
Liuqing Chen ◽  
Ji Han ◽  
Peter Childs

With the advent of the big-data era, massive information stored in electronic and digital forms on the internet become valuable resources for knowledge discovery in engineering design. Traditional document retrieval method based on document indexing focuses on retrieving individual documents related to the query, but is incapable of discovering the various associations between individual knowledge concepts. Ontology-based technologies, which can extract the inherent relationships between concepts by using advanced text mining tools, can be applied to improve design information retrieval in the large-scale unstructured textual data environment. However, few of the public available ontology database stands on a design and engineering perspective to establish the relations between knowledge concepts. This paper develops a “WordNet” focusing on design and engineering associations by integrating the text mining approaches to construct an unsupervised learning ontology network. Subsequent probability and velocity network analysis are applied with different statistical behaviors to evaluate the correlation degree between concepts for design information retrieval. The validation results show that the probability and velocity analysis on our constructed ontology network can help recognize the high related complex design and engineering associations between elements. Finally, an engineering design case study demonstrates the use of our constructed semantic network in real-world project for design relations retrieval.


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