scholarly journals Simultaneous Detection of Ascorbic Acid, Dopamine, and Uric Acid Using a Novel Electrochemical Sensor Based on Palladium Nanoparticles/Reduced Graphene Oxide Nanocomposite

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Yuyun Wei ◽  
Yangyang Liu ◽  
Zhifang Xu ◽  
Shenjun Wang ◽  
Bo Chen ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Uric Acid ◽  
Palladium Nanoparticles ◽  
Electrochemical Impedance ◽  
Simultaneous Detection ◽  
Differential Pulse ◽  
Fast Response ◽  
Electrochemical Performances ◽  
Glass Carbon Electrode ◽  
Glass Carbon

A fresh strategy based on two-step electrochemical reduction for the fabrication of palladium nanoparticles/reduced oxide nanocomposite-modified glass carbon electrode (PdNPs/rGO/GCE) was established in this study. Field emission scanning electron microscopy (FESEM) images showed that spherical PdNPs were evenly distributed on the surface of rGO-modified electrode (rGO/GCE), and the introduction of PdNPs has no effect on the morphology of rGO. Electrochemical impedance spectroscopy (EIS) studies revealed that the conductivity of PdNPs/rGO/GCE was higher than that of rGO/GCE and bare GCE. The electrochemical performances of PdNPs/rGO/GCE sensor were investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and chronoamperometry using ascorbic acid (AA), dopamine (DA), and uric acid (UA) as analytes. At the optimized conditions, wide linear ranges of 0.5–3.5 mM (R2 = 0.99), 3–15 μM (R2 = 0.99) and 15–42 μM (R2 = 0.99), and 0.3–1.4 mM (R2 = 0.99) towards AA, DA, and UA in ternary mixture were observed, respectively. In addition to superior anti-interference capability, fast response (≤5 s), excellent reproducibility, and good long-term stability were also given by this sensor. These results suggested that PdNPs/rGO/GCE is promising for the simultaneous detection of AA, DA, and UA in practical application.

scholarly journals Morphology–Dependent Electrochemical Sensing Properties of Iron Oxide–Graphene Oxide Nanohybrids for Dopamine and Uric Acid

Nanomaterials ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 835 ◽  
Author(s):  
Zhaotian Cai ◽  
Yabing Ye ◽  
Xuan Wan ◽  
Jun Liu ◽  
Shihui Yang ◽  
...  
Keyword(s):  
Uric Acid ◽  
Graphene Oxide ◽  
Iron Oxide ◽  
Electrocatalytic Activity ◽  
Electrochemical Impedance ◽  
Simultaneous Detection ◽  
Electrochemical Sensing ◽  
Electrochemical Performances ◽  
Hydrothermal Route ◽  
Sensing Properties

Various morphologies of iron oxide nanoparticles (Fe2O3 NPs), including cubic, thorhombic and discal shapes were synthesized by a facile meta-ion mediated hydrothermal route. To further improve the electrochemical sensing properties, discal Fe2O3 NPs with the highest electrocatalytic activity were coupled with graphene oxide (GO) nanosheets. The surface morphology, microstructures and electrochemical properties of the obtained Fe2O3 NPs and Fe2O3/GO nanohybrids were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) techniques. As expected, the electrochemical performances were found to be highly related to morphology. The discal Fe2O3 NPs coupled with GO showed remarkable electrocatalytic activity toward the oxidation of dopamine (DA) and uric acid (UA), due to their excellent synergistic effect. The electrochemical responses of both DA and UA were linear to their concentrations in the ranges of 0.02–10 μM and 10–100 μM, with very low limits of detection (LOD) of 3.2 nM and 2.5 nM for DA and UA, respectively. Moreover, the d-Fe2O3/GO nanohybrids showed good selectivity and reproducibility. The proposed d-Fe2O3/GO/GCE realized the simultaneous detection of DA and UA in human serum and urine samples with satisfactory recoveries.

scholarly journals SIMULTANEOUS ELECTROCHEMICAL DETECTION OF ASCORBIC ACID, DOPAMINE, AND URIC ACID AT MAGNETIC NANOPARTICLES/REDUCED GRAPHENE OXIDE MODIFIED ELECTRODE

2021 ◽  
Vol 83 (3) ◽  
pp. 85-92
Author(s):  
Azleen Rashidah Mohd Rosli ◽  
Farhanini Yusoff ◽  
Saw Hong Loh ◽  
Hanis Mohd Yusoff ◽  
Muhammad Mahadi Abdul Jamil ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Uric Acid ◽  
Graphene Oxide ◽  
Magnetic Nanoparticles ◽  
Reduced Graphene Oxide ◽  
Modified Electrode ◽  
Limit Of Detection ◽  
Simultaneous Detection ◽  
Differential Pulse ◽  
Reduced Graphene

A magnetic nanoparticles/reduced graphene oxide modified glassy carbon electrode (MNP/rGO/GCE) was fabricated via one-step facile synthesis route for the simultaneous determination of ascorbic acid (AA), dopamine (DA), along with uric acid (UA). A series of diseases and disorders has been associated with irregular levels of these respective analytes, thus early detection is highly crucial. Physical and electrochemical characterization of the modified electrode was conducted by using Scanning Electron Microscopy (SEM), Fourier Transform Infrared (FTIR) analysis, X-Ray Diffraction (XRD) analysis and Brauneur-Emmet-Teller (BET), Cyclic Voltammetry (CV) and Electron Impedance Spectroscopy (EIS). The results obtained confirmed the formation of MNP/rGO composite. Differential pulse voltammetry (DPV) of MNP/rGO/GCE displays three well-defined peaks which associated to AA, DA and UA, respectively. The response towards DA is linear in the concentration range of 15 nM to 100 µM with a detection limit of 0.19 nM while a response to AA and UA is also linear in the concentration range of 10 µM to 100 µM with a limit of detection 0.22 µM and 45 nM respectively. The proposed modified electrode offers a good response towards simultaneous detection of three different electroactive species with excellent electron transfer rate, great capacitance and ideal diffusive control behavior.

Noncovalently copper-porphyrin functionalized reduced graphene oxide for sensitive electrochemical detection of dopamine

2018 ◽  
Vol 22 (09n10) ◽  
pp. 853-862 ◽  
Author(s):  
Dong-Lan Huang ◽  
Jian Wang ◽  
Hui-Qing Yuan ◽  
Hui-Shi Guo ◽  
Xiao Ying ◽  
...  
Keyword(s):  
Electrochemical Detection ◽  
Electrochemical Impedance ◽  
Differential Pulse ◽  
Visible Spectroscopy ◽  
Glass Carbon Electrode ◽  
Copper Porphyrin ◽  
Reduced Graphene ◽  
Glass Carbon ◽  
Ft Ir ◽  
Ft Ir Spectroscopy

The nanocomposite of an electron-deficient flat tetrakis-(ethoxycarbonyl) porphyrin copper(II) (Cu-TECP) and reduced grapheme oxide (RGO) was prepared and used for electrochemical detection of dopamine (DA). The prepared nanocomposite was characterized by scanning electron microscopy, Raman spectroscopy, FT-IR spectroscopy, ultraviolet-visible spectroscopy and electrochemical impedance spectroscopy. Electrochemical studies of the modified glass carbon electrode (GCE) were carried out by the cyclic voltammetry and differential pulse voltammograms (DPV) methods. The RGO/Cu-TECP/GCE exhibited enhanced electrocatalytic activity towards the detection of dopamine (DA). The detection limit was 0.58 μM, while the linear range was from 2 to 200 μM ([Formula: see text] 0.997).

scholarly journals Carbon Black-Carbon Nanotube Co-Doped Polyimide Sensors for Simultaneous Determination of Ascorbic Acid, Uric Acid, and Dopamine

Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1691 ◽  
Author(s):  
Yue Wang ◽  
Tian Yang ◽  
Yasushi Hasebe ◽  
Zhiqiang Zhang ◽  
Dongping Tao
Keyword(s):  
Ascorbic Acid ◽  
Uric Acid ◽  
Carbon Nanotube ◽  
Carbon Black ◽  
Simultaneous Determination ◽  
Simultaneous Detection ◽  
High Sensitivity ◽  
Differential Pulse ◽  
Co Doped

Carbon black (CB) and carbon nanotube (CNT) co-doped polyimide (PI) modified glassy carbon electrode (CB-CNT/PI/GCE) was first prepared for the simultaneous determination of ascorbic acid (AA), dopamine (DA), and uric acid (UA). The CB-CNT/PI/GCE exhibited persistent electrochemical behavior and excellent catalytic activities. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used for the simultaneous detection of AA, DA, and UA in their ternary mixture. The peak separations between AA and DA, and DA and UA, are up to 166 mV and 148 mV, respectively. The CB-CNT/PI/GCE exhibited high sensitivity to DA and UA, with the detection limit of 1.9 µM and 3 µM, respectively. In addition, the CB-CNT/PI/GCE showed sufficient selectivity and long-term stability, and was applicable to detect AA, DA, and UA in human urine sample.

Gold nanoparticle-decorated MoS2 nanosheets for simultaneous detection of ascorbic acid, dopamine and uric acid

RSC Advances ◽  
2014 ◽  
Vol 4 (52) ◽  
pp. 27625 ◽  
Author(s):  
Haofan Sun ◽  
Jie Chao ◽  
Xiaolei Zuo ◽  
Shao Su ◽  
Xingfen Liu ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Uric Acid ◽  
Gold Nanoparticle ◽  
Simultaneous Detection ◽  
Mos2 Nanosheets

scholarly journals An Electrochemical Sensor Based On Graphite Electrode Modified With Silica Containing 1-N-Propyl-3-Methylimidazolium Species For Determination Of Ascorbic Acid

2019 ◽  
Vol Vol. 14, No.1 ◽  
pp. 5-14 ◽  
Author(s):  
Anastasiya Tkachenko ◽  
Mykyta Onizhuk ◽  
Oleg Tkachenko ◽  
Leliz T. Arenas ◽  
Edilson V. Benvenutt ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Cyclic Voltammetry ◽  
Electrochemical Sensor ◽  
Electrochemical Impedance ◽  
Limit Of Detection ◽  
Pharmaceutical Formulations ◽  
Differential Pulse ◽  
Long Term Stability ◽  
Diffusion Limited

In the present study, an electrochemical sensor based on the electrode (SiMImCl/C) consisting of graphite and silica, grafted with 1-n-propyl-3-methylimidazolium chloride was used for ascorbic acid (AA) quantification in pharmaceuticals and food formulations. Cyclic voltammetry and electrochemical impedance spectroscopy were applied for electrochemical characterization of the SiMImCl/C electrode. The cyclic voltammetry study revealed that the oxidation of AA on this electrode is an irreversible process, realized by adsorption and diffusion limited step. The differential pulse voltammetry was applied to develop a procedure for the AA determination. The linear range was found to be 0.3–170 μmol L-1 and the limit of detection – 0.1 μmol L-1. The proposed SiMImCl/C electrode has long term stability and does not show electrochemical activity towards the analytes, which commonly coexist with AA. The sensor was successfully used for quantification of AA in food and pharmaceutical formulations.

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