scholarly journals Gustatory Dysfunction among a Sample of Depressed Egyptian Adults under Antidepressants Therapy: A Retrospective Cohort Study

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Christine Mikhail ◽  
Khaled Elgaaly ◽  
Ahmed Abd El Latif Abd El Hamid ◽  
Olfat Shaker ◽  
Shereen Ali

It is quite clear that the ability to perceive taste sensations significantly affects food choice, which consequently affects health status in the long term. Gustatory dysfunction is a neglected symptom among the depressed patients and those under antidepressants therapy, although these patients are suspectable to oral problems, due to general self-negligence related to mental disease, fear of dental treatment, and side effects of varied medications utilized in psychiatry. This study is aimed at assessing gustatory thresholds (detection and recognition thresholds) among a sample of 30 depressed Egyptian adults under antidepressants therapy for at least 3 months or psychotherapy with age ranging from 20 to 50 years old, seeking the Psychiatric Clinic at the Faculty of Medicine, Cairo University, Egypt. These patients were distributed into three equal groups (tricyclic antidepressants (TCA), selective serotonin reuptake inhibitors (SSRIs), and psychotherapy) and were assessed for gustatory detection and recognition thresholds using the filter paper disc method through a scoring system. The participants were also divided into normal taste group in which both the detection and recognition scores were 1, while the scores from 2 till 5 were considered as hypogeusia group and the score of 6 was considered as dysgeusia group. The TCA group was statistically significant from the other 2 groups in sweet detection thresholds ( p  = 0.043) and sweet recognition thresholds ( p  = 0.007). Hypogeusia for sweet was statistically significant ( p  = 0.041), where it was more common among TCA (70%) than both SSRIs and the psychotherapy group (20%). Gustatory dysfunction was found to be mostly associated with TCA followed by SSRIs particularly for sweet taste thresholds. More attention has to be given to taste changes among these patients as oral health affects general health by causing considerable pain and by changing what people eat, their speech, and their quality of life and wellbeing. Proper awareness and evaluation of this problem will improve the quality of life for the depressed patients and avoid unnecessary treatment. This trial is registered with ClinicalTrials.gov ID: NCT03599011.

2015 ◽  
Vol 16 (2) ◽  
pp. 151-156 ◽  
Author(s):  
Sandra Matovic ◽  
Slobodan Jankovic

Abstract Depression is a disease of great social and medical importance. Quality of life can correlate with severity of manifested depression. The aim of our study was to determine whether people with unipolar depression have a poorer quality of life than healthy individuals, in what areas they have poorer quality of life and how socio-demographic characteristics and different therapies impact quality of life. The survey was conducted among 110 subjects, of which 55 were patients diagnosed with depression using ICD-10 criteria at the Psychiatric Clinic in Kragujevac and 55 were healthy subjects. Quality of life was evaluated by The Quality of Life Questionnaire compiled by the WHO. Quality of life was compared between the two groups and within research groups, depending on the applied therapy. There were statistically significant differences in quality of life between the groups: physical health - 49.64 versus 70.84, p=0.000; psychological health - 38.69 versus 69.85, p=0.000; social relations - 53.73 versus 64.89, p=0.004; living conditions - 54.58 versus 66.7, p=0.000, and in overall quality of life - 75.41 versus 96.00, p=0.000. The results showed that there was no statistically significant difference in quality of life between applied therapies. The overall quality of life of depressed patients did not depend on marital status or gender of the respondents. Depressed patients generally have a low quality of life in all domains and in overall quality of life. To improve of mental health, oOne of the primary goals to improve mental health should be to improve quality of life among depressed patients.


Author(s):  
Eman M. Khedr ◽  
Rania M. Gamal ◽  
Sounia M. Rashad ◽  
Mary Yacoub ◽  
Gellan K. Ahmed

Abstract Background Depression is common in systemic lupus erythematosus (SLE) and is an unmeasured risk factor, yet its symptoms can be neglected in standard disease evaluations. The purpose of this study was to assess the frequency and the impact of depression on quality of life in SLE patients. We recruited 32 patients with SLE and 15 healthy control volunteers in the study. The following investigations were undertaken in each patient: clinical and rheumatologic assessment, SLE Disease Activity Index-2k (SLEDAI-2k), Beck Depression Inventory (BDI), Short-Form Health Survey (SF-36) questionnaire, and routine laboratory tests. Results There was a high percentage of depression (46.9%) in the SLE patients. Regarding quality of life (SF-36), there were significant affection of the physical and mental composite summary domains (PCS and MCS) scores in lupus patients compared with controls (P < 0.000 for both) with the same significant in depressed compared with non-depressed patients. SF-36 subscales (physical function, limit emotional, emotional wellbeing, and social function) were significantly affected in depressed lupus patients compared with non-depressed patients. There was a significant negative correlation between the score of MCS domain of SF-36 with BDI (P < 0.000) while positive correlation between SLEDAI score with depression score. In contrast, there were no significant correlations between MCS or PCS with age, duration of illness, or SLEDAI-2K. Conclusions Depression is common in SLE patients and had a negative impact on quality of life particularly on MCS domain and positive correlation with disease severity score. Trial registration This study was registered on clinical trial with registration number: NCT03165682 https://clinicaltrials.gov/ct2/show/NCT03165682 on 24 May 2017.


2016 ◽  
Vol 29 (3) ◽  
pp. 507-514
Author(s):  
Maíra de Oliveira Viana ◽  
Natália Bitar da Cunha Olegario ◽  
Mariana de Oliveira Viana ◽  
Guilherme Pinheiro Ferreira da Silva ◽  
Jair Licio Ferreira Santos ◽  
...  

Abstract Introduction: Temporomandibular disorders (TMD) comprise a group of diseases that affect not only the temporomandibular joint, but also different areas extrinsic to the joints. Quality of life has been the subject of numerous studies in the Health area, especially aimed at people with chronic diseases, such as TMD. Objective: To evaluate effects of a physical therapy protocol on the quality of life of patients with temporomandibular disorder. Methods: Blinded, prospective, clinical trial, with 60 patients of both genders, aged between 18 and 70 years with TMD diagnosis attended in the clinic of Ribeirão Preto School of Dentistry. The patients were divided into two groups, with one group, in addition to dental treatment, receiving a physical therapy protocol and the other group dental treatment only, for 5 weeks. The measurement of quality of life was obtained through the generic SF-36 questionnaire, at the beginning and end of the proposed protocol. Results: The patients to whom the physical therapy protocol was applied associated with dental care presented increased scores in all the domains of the questionnaire. In the group that received only dental treatment, improvements were only found in the domain related to pain. Conclusion: The application of a physical therapy protocol was able to improve the quality of life of patients with temporomandibular disorder.


Author(s):  
V. Rollon-Ugalde ◽  
JA. Coello-Suanzes ◽  
AM. Lopez-Jimenez ◽  
J. Herce-Lopez ◽  
P. Toledano-Valero ◽  
...  

Author(s):  
Nicolas Decerle ◽  
Pierre-Yves Cousson ◽  
Emmanuel Nicolas ◽  
Martine Hennequin

Access to dental treatment could be difficult for some patients due to dental phobia or anxiety, cognitive or sensorial disabilities, systemic disorders, or social difficulties. General anesthesia (GA) was often indicated for dental surgery, and there is almost no available data on adapted procedures and materials that can be applied during GA for maintaining functional teeth on the arches and limiting oral dysfunctions. This study evaluates changes in oral health-related quality of life and mastication in a cohort of uncooperative patients treated under GA according to a comprehensive and conservative dental treatment approach. Dental status, oral health-related quality of life, chewed bolus granulometry, kinematic parameters of mastication, and food refusals were evaluated one month preoperatively (T0), and then one month (T1) and six months post-operatively (T2). One hundred and two adult patients (mean age ± SD: 32.2 ± 9.9 years; range: 18–57.7) participated in the preoperative evaluation, 87 were treated under GA of which 36 participated in the evaluation at T1 and 15 were evaluated at T2. Preoperative and postoperative data comparisons demonstrated that oral rehabilitation under GA helped increase chewing activity and oral health-related quality of life. The conditions for providing dental treatment under GA could be arranged to limit dental extractions in uncooperative patients.


2010 ◽  
Vol 50 (1) ◽  
pp. 65-68 ◽  
Author(s):  
Mariko Naito ◽  
Tomohisa Kato ◽  
Wataru Fujii ◽  
Megumi Ozeki ◽  
Michio Yokoyama ◽  
...  

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