scholarly journals Consumers’ Perception of Generic Medicines and Evaluation of In Vitro Quality Control Parameters of Locally Manufactured Paracetamol Tablets in Asmara, Eritrea: A Cross-Sectional Study

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Idris Mohammed Idris ◽  
Diyae Nesredin Hassan ◽  
Hanan Abdelkadir Hassen ◽  
Rahwa Zerabruk Araya ◽  
Dawit G. Weldemariam
Keyword(s):  
Quality Control ◽  
Generic Medicine ◽  
Cross Sectional Study ◽  
In Vitro Test ◽  
Control Parameters ◽  
Sectional Study ◽  
Generic Medicines ◽  
Cross Sectional ◽  
Quality Control Parameters

Generic medicines are clinically equivalent and can be used interchangeably for their intended use. Globally, the usage of generic medicines is highly recommended because of their affordability and accessibility. However, consumers hold a negative perception and attitude of using generic medicine as they consider it poor and having inferior quality compared to branded medicines. This study was conducted to assess the consumers’ general view of generic medicines and in vitro evaluation of a locally produced generic medicine, paracetamol. An analytical and cross-sectional study was conducted in three selected hospitals, and in vitro quality control evaluation was done in National Drug Quality Control Laboratory between October 26 and November 21, 2017, in Asmara, Eritrea. A systematic random sampling design was employed, and the data was collected using a questionnaire and a check-list for recording the quality control parameters of paracetamol tablets. A total of 403 respondents were included in the study. The majority of the study participants were females (61.8%). Generally, about half (49.1%) of the respondents choose locally manufactured paracetamol over the imported ones. More than half (68.5%) of the respondents did not believe expensive medicines are of better quality. The main reason consumers prefer the local paracetamol (Azemol) tablet to the imported one was due to their good experience (62.1%). About three-fourths (78.1%) of the consumers also believed that medicines manufactured abroad confer higher quality. At the multivariate level, having educational backgrounds such as elementary ( AOR = 4.19 , 95% CI: 1.251, 14.035) and junior ( AOR = 2.4 , 95% CI: 1.146, 5.028) was associated with preferability to local paracetamol as a pain killer over the brand ones. The in vitro test of the local paracetamol met the standard specification for the identification test, weight variation test, pharmacopeial test, friability test, disintegration test, and dissolution test. In conclusion, the majority of the consumers considered local paracetamol as having an inferior quality when compared with brand paracetamol. However, the reality revealed that the local paracetamol was of the same quality as the brand ones. To facilitate widespread use of generic medicines, healthcare professionals should educate consumers on the advantages of these medicines.

Comparison and Association of Neck Extensor Muscles’ Endurance and Postural Function in Subjects with and without Chronic Neck Pain – A Cross-Sectional Study

2021 ◽  
Author(s):  
Praveen Kumar Kandakurti ◽  
Ravi Shankar Reddy ◽  
Venkata Nagaraj Kakarparthy ◽  
Kanagaraj Rengaramanujam ◽  
Jaya Shanker Tedla ◽  
...  
Keyword(s):  
Neck Pain ◽  
Postural Control ◽  
Chronic Neck Pain ◽  
Cross Sectional Study ◽  
Control Measures ◽  
Endurance Capacity ◽  
Control Parameters ◽  
Sectional Study ◽  
Cross Sectional ◽  
Velocity Moment

Abstract Purpose Neck extensor endurance (NEE) and position sense are vital for maintaining cervical spine function and defects in these processes may be associated with impaired postural control in chronic neck pain (CNP) subjects. The study’s objectives are 1) to compare the cervical extensor endurance capability and postural control of CNP subjects with those of asymptomatic controls; 2) to investigate the association between NEE and postural control. Materials and Methods Sixty-four participants (38 asymptomatic, 38 with CNP) participated in this cross-sectional study. NEE was assessed using a clinical extensor endurance test. Under open and closed eyes conditions, postural control measures were tested with the Good Balance system. The postural control parameters were AP-velocity (mm/s), ML-velocity (mm/s) and Velocity moment (mm2). NEE capacity and postural control parameters were compared and correlated between asymptomatic and CNP subjects. Results and Discussion CNP subjects showed lower NEE capacity (p<0.001) and significantly larger AP-velocity (p<0.001), ML-velocity (p<0.001) and Velocity moment (p<0.001) than asymptomatic participants. NEE negatively correlated with AP-velocity (r=−0.51, p=0.001), ML-velocity (r=0.46, p=0.003) and velocity moment (r=0.38, p=0.020) in asymptomatic subjects in eyes open condition and no correlations in subjects with CNP. CNP subjects showed increased postural sway velocities and lowered extensor endurance capacity compared to asymptomatic participants. No correlations existed between NEE and postural control parameters in CNP subjects.

General Perception Regarding The Generic and Branded Medicines among the Visitors of the Turaif General Hospital

2021 ◽  
Vol 15 (12) ◽  
pp. 3516-3518
Author(s):  
Nawaf Alotaibi
Keyword(s):  
Saudi Arabia ◽  
General Hospital ◽  
Health Care Professionals ◽  
Generic Drugs ◽  
Generic Medicine ◽  
Cross Sectional Study ◽  
Generic Medicines ◽  
Kingdom Of Saudi Arabia ◽  
Cross Sectional ◽  
Awareness Programs

Background: The utilization of generic drugs in Saudi Arabia is under development. Many studies concerning generic drugs and their utilization by the consumers and promotion by health care professionals have been conducted in Saudi Arabia. Most of these studies revealed general unawareness of generic medicines among the Saudi people. Objective: The objective of this study was to evaluate the general perception regarding the generic medicines and branded medicines among the visitors of the Turaif general hospital. Methods: This cross‑sectional study was carried out from December 29, 2019, to January 23, 2020, at Turaif General Hospital, Turaif, Kingdom of Saudi Arabia using a questionnaire. The questionnaire was shared with the visitors (N = 527) of the hospital after their agreement, and the data were collected. The obtained data were statistically analyzed by Statistical Product and Service Solutions (SPSS) version 16. Results: The results of this study revealed that more than 50% of the participants were unaware about generic medicines and branded medicines; preferred imported generic medicines over local generics; agreed that the imported generic medicines are of high quality, more effective, and expensive as well. However, almost 50% of the participants were not sure about the quality, efficacy, safety, price, and side effects of the branded medicine. Conclusion: It has been concluded that there is a need to provide awareness programs about branded medicine, imported generic medicine, and locally manufactured generic medicines. Keywords: Branded drugs, Generic drugs, Awareness, Turaif, Saudi Arabia.

scholarly journals Hospital Advertisements in Newspapers, Is It Still Worth It?

2017 ◽  
Vol 9 (5) ◽  
pp. 27
Author(s):  
Ashraf Ahmad Zaghloul
Keyword(s):  
Quality Control ◽  
Statistical Analysis ◽  
Consumer Behavior ◽  
Medical Care ◽  
Cross Sectional Study ◽  
Sources Of Information ◽  
Sectional Study ◽  
Healthcare Organizations ◽  
Cross Sectional ◽  
Marketing Activities

INTRODUCTION: Marketing the hospital image through advertising shapes the sources of information upon which the patient takes a decision to purchase the service. Advertisement is considered to be one of the marketing activities geared towards promoting the hospital’s image. The aim of this study is to explore and investigate the determinants of consumer behavior toward newspaper advertising eye-catchers for hospitals and medical care in the UAE.METHODOLOGY: A cross-sectional study design was followed using the snowball technique to select a convenient sample of the population of Sharjah, UAE. The total number of questionnaires valid for statistical analysis accounted for a 402.RESULTS: The significant adjusted odds included in the model were occupation (Administrative) = 2.1 (CI 1.1-4.5), name and brand = 0.4 (CI 0.1-0.8), clinical staff photo = 0.2 (CI 0.1-0.7), and location = 3.9 (CI 1.3-11.9).  CONCLUSION: Healthcare organizations are required to further assess the feedback of their marketing plans especially newspaper advertisement budgets through the quality control activities performed at these organizations.

scholarly journals A survey exploring the knowledge and perceptions of senior medical students in Nepal toward generic medicines

2016 ◽  
Vol 4 ◽  
pp. 205031211666257 ◽  
Author(s):  
Sudesh Gyawali ◽  
Mohamed Azmi Hassali ◽  
Archana Saha
Keyword(s):  
Medical Students ◽  
Cost Effective ◽  
Generic Medicine ◽  
Cross Sectional Study ◽  
P Value ◽  
Brand Name ◽  
Generic Medicines ◽  
Cross Sectional ◽  
Knowledge Deficit ◽  
Almost All

Background: The accurate knowledge of generic medicine issues among future prescribers will enhance the prescribing of cost-effective medicines. This study aimed to explore the knowledge and perception of senior medical students about the generic medicines. Methodology: A cross-sectional study was conducted among 237 senior medical students (final year students and interns) using a validated self-administered questionnaire. The collected data were analyzed using Statistical Package for the Social Sciences version 20 for windows and comparison of difference was done using linear by linear association. A p value of less than 0.05 was taken as statistically significant. Results: The average age (standard deviation) of the respondents was 23.54 (1.39) years. Almost 5% of respondents correctly answered the question regarding the regulatory limits for bioequivalence. Almost two-thirds of respondents correctly agreed that generic medicine is bioequivalent to a brand-name medicine, and 79.3% and 72.5% of respondents correctly agreed that the medicine should be present in the same dosage form and same dose, respectively, as the brand-name medicines. However, almost half of the respondents had impression that brand-name medicines are required to meet higher safety standard than generic medicines. Almost 90% of respondents felt that advertisement by the drug companies would influence the use of brand-name medicine and they need more information about generic medicine. Conclusion: This study highlights the negative perception and knowledge deficit among the respondents. The students’ responses to almost all the statements were almost similar to the respondents’ academic year (final year students and interns), gender and nationality.

scholarly journals In-vitro comparative evaluation of quality control parameters between paracetamol and paracetamol/caffeine tablets available in Bangladesh

2012 ◽  
Vol 1 (5) ◽  
pp. 103-109 ◽  
Author(s):  
Palash Karmakar ◽  
Md Golam Kibria
Keyword(s):  
Quality Control ◽  
Pharmaceutical Journal ◽  
Dissolution Profile ◽  
Control Parameters ◽  
Disintegration Time ◽  
Weight Variation ◽  
Quality Control Parameters ◽  
Standard Quality ◽  
Tablet Hardness

Paracetamol is a widely used non-prescription analgesic and antipyretic medicine. The study was conducted to assess the comparative in-vitro quality control parameters through the evaluation of weight variation, hardness, friability, disintegration time and dissolution profile between the commercially available tablet brands of paraceta-mol and paracetamol/caffeine combination in Bangladesh. Tablets of five top level manufacturers those have both of the formulations were evaluated in two groups. Both similarities and dissimilarities were found between the groups. All tablets either paracetamol (1.07 to 2.14%) or paracetamol/caffeine (0.98 to 2.09%) showed acceptable weight variation and friability (below 1%). Formulations were somewhat different in their hardness, disintegration time and dissolution profile. All tablets of paracetamol/caffeine were found harder than paracetamol tablets of the same manufacturer. 1 out of 5 for paracetamol and 3 out of 5 for paracetamol/caffeine tablets exceeded the limit of tablet hardness or crushing strength. The disintegration time in 0.1N HCl of paracetamol tablet brands (24 seconds to 4 minutes 52 seconds) were less than the paracetamol/caffeine (6 minutes 33 seconds to 17 minutes 43 seconds) brands. On the other hand in phosphate buffer, pH 7.4, paracetamol/caffeine tablets dissolved quickly and showed better release profile than tablets containing only paracetamol. It can be concluded that standard quality control parameters always should be maintained not only for paracetamol or its combination but also for all kinds of medicine for getting better drug products.DOI: http://dx.doi.org/10.3329/icpj.v1i5.10282International Current Pharmaceutical Journal 2012, 1(5): 103-109

Factors that influence in vitro fertilization treatment outcomes of Chinese men: A cross-sectional study

2016 ◽  
Vol 32 ◽  
pp. 222-226 ◽  
Author(s):  
Dan Chen ◽  
Jing Ping Zhang ◽  
Ling Jiang ◽  
Huayan Liu ◽  
Ling Shu ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Treatment Outcomes ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Chinese Men
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