scholarly journals Application of Intelligent Monitoring of Percutaneous Partial Oxygen Pressure in Evaluating the Evolution of Scar Hyperplasia

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Wanle Qi ◽  
Mejia Zhuo ◽  
Yan Tian ◽  
Zhuoma Dawa ◽  
Junjie Bao ◽  
...  
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Oxygen Pressure ◽  
Hypertrophic Scar ◽  
Normal Skin ◽  
Scar Tissue ◽  
Partial Oxygen Pressure ◽  
Scar Maturation ◽  
Development And Evolution ◽  
Partial Oxygen

The study aimed to investigate the dynamic changes of percutaneous partial oxygen pressure during the development and evolution of a hypertrophic scar. Twenty cases of hypertrophic scar patients at different stages were selected. A percutaneous oxygen monitor was used to measure oxygen partial pressure in the scar and normal skin tissue at 14, 30, 60, and 90 days after surgery. The changes of oxygen partial pressure, tissue structure, HIF-1α, and VEGF expression in the scar tissue were observed, and the correlation was analyzed. In the scar maturation process, with the prolongation of time, the partial oxygen pressure in the tissue increased gradually. The expression intensity of HIF-1α and VEGF decreased gradually, HIF-1α was positively correlated with VEGF (r = 0.98, P < 0.01 ), there was a negative correlation between oxygen partial pressure and HIF-1 α expression (r = −0.92, P < 0.01 ), and it was negatively correlated with VEGF (r = −0.88, P < 0.01 ). TcPO2 measurement can be used to assess scar maturity; HIF-1 α and VEGF may play an essential role in regulating partial oxygen pressure in the scar tissue.

Interaction of human hemoglobin with oxygen in the presence of benzene and use of computer for construction of saturation curves

1986 ◽  
Vol 51 (8) ◽  
pp. 1795-1801
Author(s):  
Hana Hájková ◽  
Zdeněk Pavlíček ◽  
Vítěz Kalous
Keyword(s):  
Oxygen Saturation ◽  
Oxygen Pressure ◽  
Time Profile ◽  
Partial Oxygen Pressure ◽  
Human Hemoglobin ◽  
Allosteric Interaction ◽  
Partial Oxygen

The time profile of changes in the oxygen saturation curves of human hemoglobin in the presence of benzene was investigated. The partial oxygen pressure p50, necessary for a half saturation, decreases during the first 3.5 h of interaction of hemoglobin with benzene and did not change afterwards. The character of changes in Hill's coefficient was similar. The oxygen saturation was modeled both for hemoglobin alone and, using MWC as a model of allosteric interaction, also for hemoglobin and benzene in a computer.

scholarly journals Mismatch between Tissue Partial Oxygen Pressure and Near-Infrared Spectroscopy Neuromonitoring of Tissue Respiration in Acute Brain Trauma: The Rationale for Implementing a Multimodal Monitoring Strategy

2021 ◽  
Vol 22 (3) ◽  
pp. 1122
Author(s):  
Mario Forcione ◽  
Mario Ganau ◽  
Lara Prisco ◽  
Antonio Maria Chiarelli ◽  
Andrea Bellelli ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Oxygen Pressure ◽  
Near Infrared ◽  
Optical Signal ◽  
Brain Trauma ◽  
Partial Oxygen Pressure ◽  
Tissue Respiration ◽  
The Brain ◽  
Partial Oxygen

The brain tissue partial oxygen pressure (PbtO2) and near-infrared spectroscopy (NIRS) neuromonitoring are frequently compared in the management of acute moderate and severe traumatic brain injury patients; however, the relationship between their respective output parameters flows from the complex pathogenesis of tissue respiration after brain trauma. NIRS neuromonitoring overcomes certain limitations related to the heterogeneity of the pathology across the brain that cannot be adequately addressed by local-sample invasive neuromonitoring (e.g., PbtO2 neuromonitoring, microdialysis), and it allows clinicians to assess parameters that cannot otherwise be scanned. The anatomical co-registration of an NIRS signal with axial imaging (e.g., computerized tomography scan) enhances the optical signal, which can be changed by the anatomy of the lesions and the significance of the radiological assessment. These arguments led us to conclude that rather than aiming to substitute PbtO2 with tissue saturation, multiple types of NIRS should be included via multimodal systemic- and neuro-monitoring, whose values then are incorporated into biosignatures linked to patient status and prognosis. Discussion on the abnormalities in tissue respiration due to brain trauma and how they affect the PbtO2 and NIRS neuromonitoring is given.

Synthesis of monophase HgBa2CuO4+δ under controlled partial oxygen pressure

1995 ◽  
Vol 255 (3-4) ◽  
pp. 173-179 ◽  
Author(s):  
V.A. Alyoshin ◽  
D.A. Mikhailova ◽  
E.V. Antipov
Keyword(s):  
Oxygen Pressure ◽  
Partial Oxygen Pressure ◽  
Partial Oxygen

scholarly journals Correlation Between The Inspired Fraction Of Oxygen, Maternal Partial Oxygen Pressure, And Fetal Partial Oxygen Pressure During Cesarean Section Of Normal Pregnancies

2009 ◽  
Vol 59 (4) ◽  
pp. 452-460 ◽  
Author(s):  
Carlos Henrique Viana de Castro ◽  
Marcos Guilherme Cunha Cruvinel ◽  
Fabiano Soares Carneiro ◽  
Yerkes Pereira Silva ◽  
Antônio Carlos Vieira Cabral ◽  
...  
Keyword(s):  
Cesarean Section ◽  
Oxygen Pressure ◽  
Partial Oxygen Pressure ◽  
Partial Oxygen

Examples of the Practical Use of Non-Stoichiometric Compounds

1994 ◽  
Author(s):  
Koji Kosuge
Keyword(s):  
Solid State ◽  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Oxygen Pressure ◽  
Closed System ◽  
Electromotive Force ◽  
Solid Electrolytes ◽  
Coulometric Titration ◽  
Preparation Methods ◽  
Basic Characteristics

In this chapter, we describe four kinds of non-stoichiometric compound, which are or will be in practical use, from the viewpoint of preparation methods or utility. As a first example, the solid electrolyte (ZrO2)0.85(CaO)0.15 is described, which are discussed in Sections 1.4.6–1.4.8 from the viewpoint of basic characteristics. The second example is the magnetic material Mn–Zn ferrite, for which the control of non-stoichiometry and the manufacturing process will be described. Then the metal hydrides or hydrogen absorbing alloys, which are one of the most promising materials for storing and transporting hydrogen in the solid state, are described, mainly focusing on the phase relation. Finally, we describe the relation between the control of composition and the growth of a single crystal of the semiconductive compound GaAs, which is expected to give electronic materials for 1C and LSI etc. Solid electrolytes, which show ionic conductivity in the solid state, are considered to be potential materials for practical use, some are already used as mentioned below. Solid electrolytes have characteristic functions, such as electromotive force, ion selective transmission, and ion omnipresence. Here we describe the practical use of calcia stabilized zirconia (CSZ), (ZrO2)0.85(CaO)0.15, the structure and basic properties of which are discussed in detail in Sections 1.4.5–1.4.8. The most simple practical application of CSZ is for the gauge of oxygen partial pressure, as mentioned in Sections 1.4.7 and 1.4.8. The oxygen partial pressure P2o2 in the closed system as shown in Fig. 3.1 can be measured, taking the air as the standard oxygen pressure P1o2. The electromotive force (EMF) of this concentration cell is expressed as . . . E = (RT/4F)ln(P1o2/ P2o2) . . . This principle is applied in the measurement of oxygen partial pressure in laboratory experiments and of the oxygen activity of slag in refineries. Based on the principle of coulometric titration (see Section 1.4.8), the oxygen partial pressure of a closed system can be kept constant by feedback of the EMF, in the oxygen pressure range 1 to 10−7 atm. By use of this closed system, investigations on redox reactions of metals and also enzyme reactions have been carried out.

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