scholarly journals Feasibility Study of the “HemoTypeSC” Test for the Rapid Screening of Sickle Cell Disease in Côte D’Ivoire

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Jeannette Bassimbié Kakou Danho ◽  
Yao Nicaise Atiméré ◽  
Daouda Koné ◽  
Donafologo Daouda Yéo ◽  
Line Couitchéré
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
The Other ◽  
Rapid Screening ◽  
Cell Disease ◽  
Cote D’Ivoire ◽  
Hemoglobin S ◽  
Côte D'ivoire

Sickle cell disease is a hereditary disease that predominantly affects black people. It is very widespread in sub-Saharan Africa, particularly at the Lehmann “sickle belt” level, where the prevalence of the hemoglobin S involves at least 10% of the population in West Africa and can reach 40% in Central Africa. In Côte d’Ivoire, the prevalence of the hemoglobin S is about 12–14% in the general population and about 11.71% in the child population in Abidjan. On the other hand, its coexistence with other hemoglobin phenotypes such as AC (6.2%) and β-thalassemia (2.7%) traits may also cause composite heterogeneous sickle cell disease, e.g., SC or S/β-thalassemia in this study. Since 2009, sickle cell disease has been recognized as a public health problem; however, much still remains to be performed despite the progress achieved. The objective of this study is thus to promote a rapid screening for the struggling against sickle cell disease in Côte d’Ivoire. This study was carried out over 6 months (April–September 2019) and has included 336 children, of which 236 all-comers, recruited in the municipality of Treichville in Abidjan and 100 other children with already known hemoglobin phenotype followed up in the Hematology Department of the University Hospital of Treichville. Two tests were used: the HemoTypeSC™ for rapid screening and the hemoglobin electrophoresis which is the reference method used for confirming the diagnosis in the laboratory. The findings confirmed the reliability of the HemoTypeSC™ with a sensitivity and specificity at 100% for the detection of hemoglobin A, S, and C. On the other hand, this sensitivity and specificity drop to 98.2% and 99.7%, respectively, when we analyze all the 336 children together, including the cases with HbF detected by hemoglobin electrophoresis. Hence, the importance of performing certainty tests following the HemoTypeSC™ screening test in order to determine the accurate phenotypes and proportions of the types of hemoglobin. The prevalence of hemoglobin S in subgroup 1 of 236 children of all-comers was 15%. The HemoTypeSC™ is therefore reliable, inexpensive, and disposable for rapid screening and early detection of sickle cell disease in Côte d’Ivoire. The HemoTypeSC™ provides rapid detection of hemoglobin phenotypes HbAA, HbSS, HbSC, HbCC, HbAS, and HbAC.

scholarly journals Sensitization to Aspergillus Mix Among Atopic Sickle Cell Disease Patients in Abidjan, Côte d’Ivoire

2021 ◽  
Vol 9 (1) ◽  
pp. 1
Author(s):  
Adou Adjoumanvoule Honoré ◽  
Kabore Saydou ◽  
Dassé Sery Romuald ◽  
Yeboah Opong Richard ◽  
Goran-Kouacou Amah Patricia ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Cell Disease ◽  
Cote D’Ivoire ◽  
Côte D'ivoire

scholarly journals Immune Status and Red Cell alloimmunization among SCD Patients in Côte d’Ivoire

2018 ◽  
Vol 3 (1) ◽  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Valuable Insight ◽  
Cell Disease ◽  
Cote D’Ivoire ◽  
Côte D'ivoire ◽  
Number Of Patients ◽  
The Impact

Sickle cell disease is the most popular genetic disease in the world. In Côte d’Ivoire, the SCD prevalence is 12%. As such, SCD is a public health problem. Few studies are really investigating the relative levels of Th1, Th2 and Th17 types in black Africans and in the occurring of alloimmunization. This works attempts to identify the cytokine pattern produced by these patients during the course of the disease as Th1 cytokines, Th2 cytokines and Th17 and the relationship with alloimmunization. Patients and Methods: This is a prospective study followed at the National blood Transfusion Center in Abidjan, Côte d’Ivoire. Cytokines were measured by using Bio Legend’s LEGEND plexTM Human Inflammation Panel assays. We used Grifols DG gel® system to perform the immune hematology tests. Results: We recruit 50 patients with a diagnosis of sickle cell disease (SCD). Of these, only 31 have benefited from the research of irregular agglutinins (62%), comprising 14males (45.16%) and 17 females (54.84 %). The overall alloimmunization prevalence of 16.12%. The prevalence of alloimmunization was significantly greater in males than in females (60%). According to alloimmunization, we note an increased levels of IL-10 in non alloimmunized patients with SCD, when compared with alloimmunized and the levels of IL-4 was higher in alloimmunized patients compared to non alloimmunized. Lower IFN-γ levels were detected in non alloimmunized and alloimmunized SCD patients. Concerning IL-17, there was a small increase in patients without alloantibodies compared to those with. However no significant differences were noted in the 2 groups. Conclusion: The impact of biomarkers in the occurrence of alloimmunization is a constant preoccupation of researchers. Due to lack of financial aspect, small number of patients was enrolled. Even, we cannot draw any definitive conclusion; however our study brings data regarding the functioning of the immune system in SCD giving valuable insight.

scholarly journals Th1 and Th2 Cytokines Pattern among Sickle Cell Disease Patients in Côte d’ivoire

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Liliane K. Siransy ◽  
Chiayé C.A. Yapo-Crézoit ◽  
Maxime K. Diane ◽  
Sidonie Goore ◽  
Saydou Kaboré ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Th2 Cytokines ◽  
Cell Disease ◽  
Cote D’Ivoire ◽  
Côte D'ivoire ◽  
Th1 And Th2 Cytokines ◽  
Th1 And Th2

scholarly journals Impact of social distancing measures on the daily number of new COVID-19 cases in Côte d’Ivoire: a retrospective cohort study

2021 ◽  
Author(s):  
Teegwende V. Porgo ◽  
Khadidja Malloum Boukar ◽  
Ezechiel A. Djallo ◽  
Richard Quansah Amissah ◽  
Coralie Assy ◽  
...  
Keyword(s):  
Cohort Study ◽  
Incidence Rate ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
The Other ◽  
Cote D’Ivoire ◽  
Social Distancing ◽  
Daily Number ◽  
Côte D'ivoire ◽  
Period 2

AbstractIntroductionCôte d’Ivoire is facing a second wave of the novel coronavirus disease 2019 (COVID-19). While social distancing measures (SDM) may be an option to address this wave, SDM may be devastating, especially if they have a minimal impact on the spread of COVID-19, given the other measures in place.MethodsWe conducted a cohort study involving cases that had occurred as at June 30, 2020. We used data from the Government’s situation reports. We established three study periods, which correspond to the implementation and easing of SDM, including a 10-day delay for test results: (1) the SDM (March 11 - May 24), (2) the no SDM (May 25 - June 21), and (3) the pseudo SDM (June 22 - July 10) periods. We compared the incidence rate during these periods using Poisson regression, with sex, age, and the average daily number of tests as covariates.ResultsAs at July 10, there were 12,052 cases. The incidence rate was 100% higher during period 2 compared to period 1 (incidence rate ratio = 2.05, 95% confidence interval: 1.75-2.41) and 25% lower during period 3 compared to period 2 (0.75 [0.66-0.86]).ConclusionsThe easing and subsequent reinforcement of SDM had a significant impact on the spread of COVID-19 in Côte d’Ivoire. The other mitigation measures either did not compensate for the easing of the SDM during the no SDM period or were not fully effective throughout the study periods; they should be strengthened before the SDM are reimplemented.

Modernity, Autochthony and the Ivorian Nation: the End of a Century in Côte d'Ivoire

Africa ◽  
2010 ◽  
Vol 80 (4) ◽  
pp. 527-552 ◽  
Author(s):  
Armando Cutolo
Keyword(s):  
Public Space ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
The Other ◽  
The Political ◽  
Bare Life ◽  
Cote D’Ivoire ◽  
Post Colonial ◽  
Historical Continuity ◽  
Côte D'ivoire

ABSTRACTIn the mid-1990s, Côte d'Ivoire witnessed the rise of the ideology of ivoirité, a conception of citizenship based on autochthonous origins. Ivoirité was elaborated by a group of Ivorian intellectuals in the context of the political struggle opposing Henry Konan Bedié to Alassane Ouattara in the succession to the late President Houphouët-Boigny. Through the tactical use of the rhetoric of ivoirité, Ouattara was depicted by his adversaries as a ‘Burkinabé’ trying to rule the country. Going beyond this tactical aspect, the article addresses the ideological relations linking ivoirité to the ‘project of an Ivorian liberal society’ explicitly constructed by the same intellectuals. These relations contributed to the emergence, in the Ivorian public space, of a discourse establishing self-evident, hegemonic connections between notions like autochthony, modernity and nationality, on the one hand, and biopolitical concepts like population, immigration, security and resources on the other. The article uses two complementary perspectives to frame this emergent discourse. One focuses on the historical continuity of the political-economic strategies and population policies implemented by colonial governments and post-colonial elites. The other uses Giorgio Agamben's critical enquiry into citizenship and nationality to bring to light the implication of the ivoirité intellectuals in the construction of a national bios, and thus in the singling out of a paradigmatic form of bare life.

scholarly journals Ethnobotanical study of medicinal plants used against sickle cell anaemia in the eastern part of the Côte d’Ivoire

2020 ◽  
Vol 45 (1) ◽  
pp. 7839-7852
Author(s):  
Akakpo-Akue J ◽  
Kplé T.K.M ◽  
Coulibaly Kiyinlma ◽  
AHON Gnamien Marcel ◽  
Fofié Yvette ◽  
...  
Keyword(s):  
Sickle Cell ◽  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Stem Bark ◽  
Traditional Healers ◽  
Ethnobotanical Study ◽  
Ethnobotanical Survey ◽  
Cote D’Ivoire ◽  
Plant Parts ◽  
Côte D'ivoire

An ethnobotanical survey was conducted to record the various plant families, species, and plant parts used to manage sickle cell disease in the Indenié-Djouablin region eastern Côte d’Ivoire. Nine traditional healers aged 36 to 67 years old were selected in six different villages according to their reputation in knowledge of traditional medicine, their availability and their willingness to share information. A total of 26 species of plants belonging to 20 families were reported to have antisickling activity. Eleven (11) different medication recipes were composed from these 26 species of plants ((Afromonum melegueta (Roscoe) K. Schum., Xylopia aethiopica) mainly). The main plant parts used were stem bark (38%) followed by fruit (18%) and seeds (18%). The majority of the main plants recorded (84.61 %) were wild. From the recorded plants, 65.38 % were trees and 23.07 % shrubs. Most remedies (82%) were made up by decoction and were employed orally (54 %) or by enema (32 %). The potential anti-sickling activity of the plant species recorded during this study could be the effect of alkaloids, polyphenols, quinones and terpenoids compounds found during the phytochemical screening of the 26 plants species.

scholarly journals L’influence De La Contrebande Sur Le Developpement De La Ville Frontaliere De Niable Au Centre-Est De La Cote d’Ivoire

2016 ◽  
Vol 12 (5) ◽  
pp. 313
Author(s):  
Atta Koffi ◽  
Gogbe Téré ◽  
Kouassi Nguessan Gilbert ◽  
Kouadio Datté Anderson
Keyword(s):  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
The Other ◽  
Spatial Change ◽  
Modus Operandi ◽  
Cote D’Ivoire ◽  
Côte D'ivoire ◽  
Border Town ◽  
The One ◽  
The Town

In the border town of Niablé, smuggling is omnipresent. The operation of this activity is based on the one hand, on social cultural relationship between neigh boring populations, and on the other hand on monetary disparities between Ghana and Côte d’Ivoire. Without denying the truth fullness of such an activity, smugglers, organized in a highly hierarchical system operate according to a strict behavioral code where one’s given word and mutual confidence are the sole modus operandi. It permits them to bring goods of diverse natures (oil products, food, pharmaceuticals, second-hand clothes drinks, etc.) in Niablé. Thus, this activity seems to be a real opportunity for these smugglers, longing for the improvement of their welfare. Besides, the smuggling allows its actors to contribute to the town’s blossoming. Such a perception of smuggling gives an idea of the animation going on in this border town. In a word, though we want it or not smuggling participates in the socio-spatial change of the town even if sometimes, it stands as an obstacle to its development. Through this contribution, we are willing to show the operation of smuggling and its influence on the town of Niablé.

scholarly journals Fat Content and Fatty Acids Profile in Follow-on Formulas Commercialized in Côte d'Ivoire

2019 ◽  
Vol 3 (2) ◽  
pp. 54
Author(s):  
André Philippe S. Kpaibé ◽  
Yao Aya K.A. Kouassi ◽  
N’goran Jean Simon T. Yao ◽  
Alexandre Koko N’bra ◽  
Sylvain K. Dibi ◽  
...  
Keyword(s):  
Cote D'ivoire ◽  
Côte D’Ivoire ◽  
Gravimetric Method ◽  
The Other ◽  
Cote D’Ivoire ◽  
Market Control ◽  
Fatty Acids Profile ◽  
Côte D'ivoire ◽  
Post Market

<p><em>This study evaluates the follow-on formula for infants. These products are available under several brands in the Ivorian market. In order to verify their conformity to the WHO standards a post-market control by gravimetric method and gas chromatography with mass spectrometry is executed to evaluate the quantity and quality of fat products contained in the milks of brands available in Côte d’Ivoire. Out of the nine brands of milks analyzed, only four of them were close to the values revealed by their manufacturers, whereas the other products had their values below their respective indications.</em></p>

Sign in / Sign up

Export Citation Format

Share Document