Probably the Mycobacterium avium Complex around the Staple Line Exacerbated after Radiation Therapy

The space around the staple line after lung surgery is at high risk of nontuberculosis Mycobacterium pulmonary disease (NTM-PD). Solitary nodules of NTM-PD around the staple line are difficult to distinguish from lung cancer. There is no clear identification from laboratory data and radiologic findings without histological examination. In the present case, we misdiagnosed the pulmonary granulomas with Mycobacterium avium complex pulmonary disease (MAC-PD) as a recurrence of lung cancer. We conducted radiation therapy. The pulmonary granulomas with MAC-PD were exacerbated by irradiation. The effects of radiation therapy for MAC-PD are unknown. When radiation therapy is performed for the patient coexistence with MAC-PD, we should pay attention to exacerbation of MAC-PD.

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Characteristics of Mycobacterium avium complex (MAC) pulmonary disease in previously treated lung cancer patients

Respiratory Medicine Case Reports ◽

10.1016/j.rmcr.2017.06.012 ◽

2017 ◽

Vol 22 ◽

pp. 70-73 ◽

Cited By ~ 2

Author(s):

Erin Meier ◽

Kelly Pennington ◽

Alice Gallo de Moraes ◽

Patricio Escalante

Keyword(s):

Lung Cancer ◽

Cancer Patients ◽

Pulmonary Disease ◽

Mycobacterium Avium ◽

Mycobacterium Avium Complex ◽

Lung Cancer Patients ◽

Previously Treated

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A Low Body Mass Index Is Associated with Unsuccessful Treatment in Patients with Mycobacterium avium Complex Pulmonary Disease

Journal of Clinical Medicine ◽

10.3390/jcm10081576 ◽

2021 ◽

Vol 10 (8) ◽

pp. 1576

Author(s):

Hironori Sadamatsu ◽

Koichiro Takahashi ◽

Hiroki Tashiro ◽

Koji Kusaba ◽

Tetsuro Haraguchi ◽

...

Keyword(s):

Body Mass Index ◽

Pulmonary Disease ◽

Body Mass ◽

Mycobacterium Avium ◽

Mycobacterium Avium Complex ◽

Laboratory Data ◽

Poor Prognostic Factor ◽

Unsuccessful Treatment ◽

Low Body Mass Index ◽

Low Bmi

Background: A low body mass index (BMI) has been reported to be a poor prognostic factor for Mycobacterium avium complex pulmonary disease (MAC-PD). The purpose of this study was to clarify the clinical features of MAC-PD in cases with a low BMI. Methods: This retrospective study analyzed the data of patients diagnosed with MAC-PD at Saga University Hospital between 2008 and 2019. The analyzed patient characteristics included age, gender, BMI, symptoms, laboratory data, chest computed tomography findings, and the treatment courses. We also investigated the factors associated with successful treatment. Results: In total, 144 patients were included in this study. The low-BMI group (BMI < 18.5 kg/m2) had a higher incidence of sputum, Mycobacterium intracellurare infection, and cavitary lesions, in addition to lower blood lymphocyte counts, higher neutrophil–lymphocyte ratios, and a lower prognostic nutritional index (PNI) when compared to the preserved-BMI group (BMI ≥ 18.5 kg/m2). Sixty-six of the 144 patients (45.8%) received treatment. Hemosputum, acid-fast bacillus sputum smear positivity, low lymphocyte counts, a low PNI, and unsuccessful treatment (48.5% vs. 24.2%, p < 0.05) were found to be associated with a low BMI. Conclusions: A low BMI is associated with cavitary lesions, malnutrition, and unsuccessful treatment in MAC-PD.

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