scholarly journals Diagnostic Evaluation of Pancreatic Carcinoma and Chronic Pancreatitis by Pancreatoscopy

1997 ◽  
Vol 3 (3) ◽  
pp. 177-182 ◽  
Author(s):  
Hisao Tajiri
Keyword(s):  
Image Processing ◽  
Pancreatic Cancer ◽  
Chronic Pancreatitis ◽  
Pancreatic Carcinoma ◽  
Pancreatic Duct ◽  
Diagnostic Ability ◽  
Charge Coupled Device ◽  
Adaptive Enhancement ◽  
A Charge ◽  
Better Than

We succeeded in viewing the image of pancreatic duct on a TV monitor as a sequential electronic endoscope image by connecting a converter with a charge-coupled device to an ultra-thin pancreatoscope. Spacial image processing by adaptive enhancement, using an electronic endoscope, was studied in the pancreatoscope images of 18 cases (10 with pancreatic cancer and 8 with chronic pancreatitis). As a result, it became clear that the images obtained in Peak 2 of adaptive enhancement are much better than the original images. There was an excellent effect of clearly detecting the characteristic mucosal patterns in pancreatic cancer and chronic pancreatitis. We are convinced that this method would be very useful in improving the diagnostic ability of pancreatic cancer using an ultra-thin pancreatoscope.

scholarly journals Vascularisation Pattern of Chronic Pancreatitis Compared with Pancreatic Carcinoma: Results from Contrast-Enhanced Endoscopic Ultrasound

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Michael Hocke ◽  
Christoph F. Dietrich
Keyword(s):  
Pancreatic Cancer ◽  
Chronic Pancreatitis ◽  
Pancreatic Carcinoma ◽  
Endoscopic Ultrasound ◽  
Clinical Medicine ◽  
Pancreatic Tissue ◽  
Mechanical Index ◽  
Contrast Enhanced ◽  
Inflammatory Processes ◽  
Doppler Techniques

Discriminating between focal chronic pancreatitis and pancreatic cancer is always a challenge in clinical medicine. Contrast-enhanced endoscopic ultrasound using Doppler techniques can uniquely reveal different vascularisation patterns in pancreatic tissue alterated by chronic inflammatory processes and even allows a discrimination from pancreatic cancer. This paper will describe the basics of contrast-enhanced high mechanical index endoscopic ultrasound (CEHMI EUS) and contrast enhanced low mechanical index endoscopic ultrasound (CELMI EUS) and explain the pathophysiological differences of the vascularisation of chronic pancreatitis and pancreatic carcinoma. Furthermore it will discuss how to use these techniques in daily clinical practice.

scholarly journals Development and Certification of A Visibility-Range Monitor By Image Processing

1989 ◽  
Vol 13 ◽  
pp. 117-119
Author(s):  
Keishi Ishimoto ◽  
Masao Takeuchi ◽  
Shigeyuki Naitou ◽  
Haruki Furusawa
Keyword(s):  
Image Processing ◽  
Vertical Distribution ◽  
Video Camera ◽  
Measuring System ◽  
Blowing Snow ◽  
Snow Surface ◽  
Charge Coupled Device ◽  
Visibility Range ◽  
A Charge ◽  
The Vertical Distribution

A new visibility-range measuring system has been developed which uses a video camera, and with which visibility can be estimated by measuring the brightness contrast of a black target against a standardized background. This principle has been applied to development of the new visibility-range monitor described in this paper. In this monitor, a charge-coupled device (CCD) video camera measures the brightness of an arbitrary area in its range of vision, and visibility range measured by the video camera in blowing snow can be compared with that measured by the transmissometer-type visibility-range monitor and can also be calculated by direct observation using optical targets. The new sytem can monitor visibility and record information about traffic on highways at 1 s intervals for a maximum of six separate positions. The vertical distribution of visibilities over a snow surface has been observed, and it has been found that the fluctuation in visibility is greatest at lower levels above the ground in blowing snow.

Genetic instability in grossly normal pancreatic duct cells from patients with chronic pancreatitis and pancreatic cancer

2000 ◽  
Vol 118 (4) ◽  
pp. A196
Author(s):  
Alyssa M. Brown ◽  
Mary P. Bronner ◽  
Teri Brentnall ◽  
Peter S. Rabinovitch ◽  
Katie R. Carter ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Chronic Pancreatitis ◽  
Pancreatic Duct ◽  
Genetic Instability ◽  
Duct Cells ◽  
Pancreatic Duct Cells

Research on Magnet Excitation and Image Processing Used in Visual Detection

2011 ◽  
Vol 216 ◽  
pp. 793-797
Author(s):  
Li Bing Bai ◽  
Shu Lin Tian ◽  
Yu Hua Cheng
Keyword(s):  
Image Processing ◽  
Eddy Current ◽  
Visual Detection ◽  
Polarized Light ◽  
Ccd Camera ◽  
Experimental Tests ◽  
Laser Source ◽  
Magnetic Excitation ◽  
Charge Coupled Device ◽  
A Charge

A novel visual detection set, which can detect sub-superficial defects in conductive specimens, is presented in this paper. The set has a laser source, a charge coupled device (CCD) camera, and a magnetic excitation. The linear polarized light given off by the laser source is modulated by the superimposition of the magnetic fields induced by the coil and eddy current, and acquired by the CCD. Given the exciting current is known and the eddy current is influenced by the defects, the information of defects can be extracted from the image acquired by CCD. The magnet excitation and image processing are described in detail. Experimental tests have been done and the method presented is proved by the experimental results.

scholarly journals Development and Certification of A Visibility-Range Monitor By Image Processing

1989 ◽  
Vol 13 ◽  
pp. 117-119
Author(s):  
Keishi Ishimoto ◽  
Masao Takeuchi ◽  
Shigeyuki Naitou ◽  
Haruki Furusawa
Keyword(s):  
Image Processing ◽  
Vertical Distribution ◽  
Video Camera ◽  
Measuring System ◽  
Blowing Snow ◽  
Snow Surface ◽  
Charge Coupled Device ◽  
Visibility Range ◽  
A Charge ◽  
The Vertical Distribution

A new visibility-range measuring system has been developed which uses a video camera, and with which visibility can be estimated by measuring the brightness contrast of a black target against a standardized background. This principle has been applied to development of the new visibility-range monitor described in this paper. In this monitor, a charge-coupled device (CCD) video camera measures the brightness of an arbitrary area in its range of vision, and visibility range measured by the video camera in blowing snow can be compared with that measured by the transmissometer-type visibility-range monitor and can also be calculated by direct observation using optical targets.The new sytem can monitor visibility and record information about traffic on highways at 1 s intervals for a maximum of six separate positions. The vertical distribution of visibilities over a snow surface has been observed, and it has been found that the fluctuation in visibility is greatest at lower levels above the ground in blowing snow.

scholarly journals Activated Pancreatic Stellate Cells Enhance the Warburg Effect to Cause the Malignant Development in Chronic Pancreatitis

2021 ◽  
Author(s):  
Tao Ye ◽  
Shao Feng ◽  
Liu Zheng ◽  
Cai Ming ◽  
Meng Futao ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Chronic Pancreatitis ◽  
Epithelial Cells ◽  
Pancreatic Duct ◽  
Cancer Cells ◽  
Stellate Cells ◽  
Glycolytic Enzymes ◽  
Pancreatic Stellate Cells ◽  
Migration And Invasion ◽  
Pancreatic Cancer Cells

Abstract Background: Chronic pancreatitis (CP) is a precancerous condition associated with pancreatic ductal adenocarcinoma (PDAC), but its evolutionary mechanism is unclear. pancreatic stellate cells (PSCs) are closely related to the occurrence and development of CP and PDAC. We aimed to find out whether PSCs play a key role in this " inflammationcancer transition ". Methods: To evaluate the effect of activated pancreatic stellate cells on normal pancreatic duct epithelial cells and pancreatic cancer cells, pancreatic stellate cells isolated from human tissues were co-cultured with these two cells, respectively. Functional assays assessed the proliferation, migration, and invasion of these two cells. RT-qPCR and western blotting were used to detect the mRNA and protein expressions of glycolytic enzymes in these two cells. Lactate production and glucose utilization assays assessed the aerobic glycolysis level of these two cells. Immunohistochemistry was used to detect the expression of glycolytic enzymes and α-SMA, and the correlation between the two was analyzed in human tissues. Results: Our research found that co-culture with activated PSCs promoted the proliferation, migration and invasion of normal pancreatic duct epithelial cells and pancreatic cancer cells. At the same time, activated PSCs had a significant effect on the expression of the glycolytic enzymes PKM2 and LDHA in normal pancreatic duct epithelial cells and pancreatic cancer cells and increased lactic acid production and glucose consumption in these two cells. In vivo experiments showed that the expression of the glycolytic enzymes PKM2 and LDHA in pancreatic duct epithelial cells and the marker protein (α-SMA) of activated PSCs in the pancreatic duct peripancreatic interstitium were higher in pancreatic cancer tissues and chronic pancreatitis tissues than in normal pancreatic tissues in both animals and humans. In addition, analysis of human tissue specimens showed that there is a correlation between the expression of PKM2/LDHA and α-SMA. Conclusion: These findings indicate that activated PSCs play an important role in the development and progression of chronic pancreatitis into pancreatic cancer by regulating and promoting aerobic glycolysis. Our research provides a new theoretical basis for further understanding the mechanism of CP malignancy and the selection of targets for reversing CP malignancy.

Using laser speckle to measure the roughness of paper

TAPPI Journal ◽  
2011 ◽  
Vol 10 (3) ◽  
pp. 7-13
Author(s):  
ABDIEL PINO ◽  
JOSEP PLADELLORENS ◽  
JOSEP F. COLOM ◽  
ORIOL CUSOLA ◽  
AGUSTÍN TOSAS
Keyword(s):  
Image Processing ◽  
Speckle Pattern ◽  
Ccd Camera ◽  
Laser Speckle ◽  
Charge Coupled Device ◽  
Paper Surface ◽  
Surface Profiling ◽  
Base Paper ◽  
Occurrence Matrix ◽  
A Charge

Paper surface roughness is an important consideration in paper and board destined for printing. The amount of coating and method of application depend on the roughness of the base paper. We present a method to measure the roughness of the paper based on analysis of speckle pattern on the surface. Images are captured by means of a simple configuration using a laser and a charge-coupled device (CCD) camera. Then, we apply digital image processing using a co-occurrence matrix, providing for a noncontact surface profiling method that can be used online.

scholarly journals Endoscopic ultrasound findings and pathological features of pancreatic carcinoma in situ

2019 ◽  
Vol 07 (04) ◽  
pp. E585-E593 ◽  
Author(s):  
Yoshihiro Izumi ◽  
Keiji Hanada ◽  
Akihito Okazaki ◽  
Tomoyuki Minami ◽  
Naomichi Hirano ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Pancreatic Carcinoma ◽  
Pancreatic Duct ◽  
Endoscopic Ultrasound ◽  
Carcinoma In Situ ◽  
Fatty Infiltration ◽  
Pathological Features ◽  
Histological Findings ◽  
Diagnostic Features

Abstract Background and study aims Few studies have evaluated detection of pancreatic carcinoma in situ (PCIS). We evaluated findings of endoscopic ultrasound (EUS) and pathological features of PCIS. Patients and methods We histopathologically studied 16 patients with PCIS following EUS. Diagnostic features evaluated retrospectively included stricture of the main pancreatic duct (MPD) on EUS, presence or absence of hypoechoic areas surrounding the MPD stricture on EUS, the noncancerous part (pancreas of background) on EUS and histopathology, and histological findings adjacent to the area of PCIS. Results On EUS, stricture of the MPD was found in 15 patients (93.8 %). Hypoechoic areas surrounding the MPD stricture were observed in 9 patients (56.3 %), including three (18.8 %) with a 10- to 11-mm hypoechoic mass. EUS findings of the noncancerous part indicated chronic pancreatitis in six patients (37.5 %), pancreatic fatty infiltration in seven (43.8 %), early chronic pancreatitis in two (12.5 %), and normal pancreas in one (6.3 %). Histological findings of the noncancerous part (proximal to the MPD stricture) indicated chronic pancreatitis in 13 patients (81.3 %) and pancreatic fatty infiltration in five patients (31.3 %). Histopathologically, subepithelial inflammatory cell infiltration and fibrosis were present in all 16 patients with PCIS. Conclusions PCIS frequently causes localized changes in inflammation and fibrosis around the pancreatic duct. PCIS often accompanies chronic pancreatitis and pancreatic fatty infiltration in the background of the pancreas. EUS offers sufficient resolution to demonstrate pancreatic changes of PCIS.

scholarly journals Activated Pancreatic Stellate Cells Enhance the Warburg Effect to Cause the Malignant Development in Chronic Pancreatitis

2021 ◽  
Author(s):  
Tao Ye ◽  
Shao Feng ◽  
Liu Zheng ◽  
Cai Ming ◽  
Meng Futao ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Chronic Pancreatitis ◽  
Epithelial Cells ◽  
Pancreatic Duct ◽  
Cancer Cells ◽  
Stellate Cells ◽  
Monocarboxylate Transporter ◽  
Pancreatic Stellate Cells ◽  
Glucose Transporter 1 ◽  
Pancreatic Cancer Cells

Abstract Chronic pancreatitis (CP) is a precancerous condition associated with pancreatic ductal adenocarcinoma (PDAC), but its evolutionary mechanism is unclear. Pancreatic stellate cells (PSCs) are closely related to the occurrence and development of CP and PDAC, but it is not clear whether PSCs play a key role in this "inflammation-cancer transition". Our research found that co-culture with activated PSCs promoted the proliferation, migration and invasion of normal pancreatic duct epithelial cells and pancreatic cancer cells. At the same time, activated PSCs had a significant effect on the expression of the glycolysis markers (pyruvate kinase M2, lactate dehydrogenase A, glucose transporter 1, hexokinase-II and monocarboxylate transporter 4; PKM2, LDHA, GLUT1, HK2 and MCT4) in normal pancreatic duct epithelial cells and pancreatic cancer cells and increased lactic acid production and glucose consumption in these two cells. In vivo experiments showed that the expression of the glycolysis markers in pancreatic duct epithelial cells and the marker protein (α-SMA) of activated PSCs in the pancreatic duct peripancreatic interstitium were higher in pancreatic cancer tissues and chronic pancreatitis tissues than in normal pancreatic tissues in both animals and humans. In addition, analysis of human tissue specimens showed that there is a correlation between the expression of glycolysis markers and α-SMA. These findings indicate that activated PSCs play an important role in the development and progression of chronic pancreatitis into pancreatic cancer by regulating and promoting aerobic glycolysis. Our research provides a new theoretical basis for further understanding the mechanism of CP malignancy and the selection of targets for reversing CP malignancy.

Percutaneous Pancreatography under Ultrasonographic Guidance

1996 ◽  
Vol 37 (1P1) ◽  
pp. 75-78 ◽  
Author(s):  
M. Opačić ◽  
N. Rustemović ◽  
R. Pulanić ◽  
B. Vucelić ◽  
M. Frković ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Pancreatic Carcinoma ◽  
Pancreatic Duct ◽  
Good Alternative ◽  
Pancreatic Disease ◽  
Contrast Injection ◽  
Alternative Method ◽  
Fluoroscopic Control ◽  
Ultrasonographic Guidance

Purpose: The aim of the study was to evaluate percutaneous pancreatography as an alternative method for pancreatic duct visualisation in patients with pancreatic disease. Material and Methods: In 21 patients with pancreatic disease and previously unsuccessful ERCP, puncture of the pancreatic duct was carried out under ultrasonographic guidance with an 0.7-mm Chiba needle, and contrast injection was made under fluoroscopic control in the pancreatic duct. Results: The procedure was successful in 18 patients (86%). In 10 patients, chronic pancreatitis was found, and in 8 patients, pancreatic carcinoma. Conclusion: Percutaneous pancreatography is a good alternative method for visualisation of the pancreatic duct in patients with pancreatic disease and previously unsuccessful ERCP.

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