Abstract 1349: Xenograft models of human acute myeloid leukemia (AML) with biomarker strategies are valuable in development of new drugs targeting AML

2012 ◽  
Author(s):  
Lan Zhang ◽  
Taiping Chen ◽  
Qian Shi ◽  
Juan Zhang
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
New Drugs ◽  
Human Acute Myeloid Leukemia ◽  
Xenograft Models ◽  
Acute Myeloid

scholarly journals Optimized depletion of chimeric antigen receptor T cells in murine xenograft models of human acute myeloid leukemia

Blood ◽  
2017 ◽  
Vol 129 (17) ◽  
pp. 2395-2407 ◽  
Author(s):  
Sarah K. Tasian ◽  
Saad S. Kenderian ◽  
Feng Shen ◽  
Marco Ruella ◽  
Olga Shestova ◽  
...  
Keyword(s):  
T Cells ◽  
Acute Myeloid Leukemia ◽  
Stem Cell ◽  
Myeloid Leukemia ◽  
Car T Cells ◽  
Key Points ◽  
Car T ◽  
Human Acute Myeloid Leukemia ◽  
Xenograft Models ◽  
Acute Myeloid

Key Points Depletion of CD123-redirected CAR T cells with monoclonal antibodies preserves leukemia remission in human AML xenograft models. AML CAR T-cell depletion enhances feasibility of subsequent allogeneic stem cell transplantation.

Negative regulation of the LKB1/AMPK pathway by ERK in human acute myeloid leukemia cells

2015 ◽  
Vol 43 (7) ◽  
pp. 524-533.e1 ◽  
Author(s):  
Ichiro Kawashima ◽  
Toru Mitsumori ◽  
Yumi Nozaki ◽  
Takeo Yamamoto ◽  
Yuki Shobu-Sueki ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Negative Regulation ◽  
Leukemia Cells ◽  
Ampk Pathway ◽  
Human Acute Myeloid Leukemia ◽  
Acute Myeloid Leukemia Cells ◽  
Acute Myeloid
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