Abstract 701: The acute phase response identifies cancer patients with adverse outcomes from SARS-CoV-2 infection as quantified by the OnCovid Inflammatory Score

Author(s):  
Gino M. Dettorre ◽  
Saoirse Dolly ◽  
Angela Loizidou ◽  
John Chester ◽  
Amanda Jackson ◽  
...  
2008 ◽  
Vol 23 (1) ◽  
pp. 31-35 ◽  
Author(s):  
S. Battistelli ◽  
M. Stefanoni ◽  
R. Petrioli ◽  
A. Genovese ◽  
R. Dell'Avanzato ◽  
...  

Aim To investigate the plasma levels and prevalence of the most common antiphospholipid antibodies, as well as their relationships with several plasma markers of inflammation, in order to characterize some aspects of cancer thrombophilia. Materials and methods Eighty-three cancer patients with non-metastatic colorectal solid tumors and 94 control subjects were tested for the presence of IgG/IgM/IgA anti-cardiolipin and anti-β2-glycoprotein I antibodies and of several acute-phase reactants, i.e., fibrinogen, factor VIII:C and C4b-binding protein. Results In cancer patients the plasma levels of the acute-phase reactants and the IgA/IgG anti-cardiolipin and IgA anti-β2-glycoprotein I antibodies were significantly higher; the acute-phase reactants were significantly correlated with anti-cardiolipin antibodies; the prevalence of antiphospholipid antibodies was not significantly higher. Conclusions In patients with non-metastatic colorectal cancer the acute-phase response is associated with antiphospholipid generation. This could represent a further pathogenetic mechanism for the short-term post-surgery thrombotic complications of patients with colorectal cancer.


1995 ◽  
Vol 14 ◽  
pp. 13-14 ◽  
Author(s):  
T. Preston ◽  
C. Slater ◽  
D.C. McMillan ◽  
J.S. Falconert ◽  
K.C.H. Fearont

2011 ◽  
Vol 20 (8) ◽  
pp. 1823-1829 ◽  
Author(s):  
Zoe Giannousi ◽  
Ioannis Gioulbasanis ◽  
Athanasios G. Pallis ◽  
Alexandros Xyrafas ◽  
Danai Dalliani ◽  
...  

1998 ◽  
Vol 128 (8) ◽  
pp. 1355-1360 ◽  
Author(s):  
Tom Preston ◽  
Christine Slater ◽  
Donald C. McMillan ◽  
J. Stuart Falconer ◽  
Alan Shenkin ◽  
...  

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