Abstract P5-12-07: Influence of aromatase inhibitor-related adverse events on the prognosis in postmenopausal Japanese patients with breast cancer: A prospective multicenter cohort study on patient-reported outcomes

2020 ◽  
Author(s):  
Chiyomi Egawa ◽  
Shintaro Takao ◽  
Kazuhiro Yamagami ◽  
Masaru Miyashita ◽  
Masashi Baba ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cohort Study ◽  
Adverse Events ◽  
Aromatase Inhibitor ◽  
Patient Reported Outcomes ◽  
Japanese Patients ◽  
Multicenter Cohort Study ◽  
Multicenter Cohort ◽  
Patient Reported

Classification of and Risk Factors for Estrogen Deprivation Pain Syndromes Related to Aromatase Inhibitor Treatments in Women With Breast Cancer: A Prospective Multicenter Cohort Study

2014 ◽  
Vol 15 (3) ◽  
pp. 293-303 ◽  
Author(s):  
Francoise Laroche ◽  
Joël Coste ◽  
Terkia Medkour ◽  
Paul Henri Cottu ◽  
Jean-Yves Pierga ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cohort Study ◽  
Aromatase Inhibitor ◽  
Estrogen Deprivation ◽  
Multicenter Cohort Study ◽  
Pain Syndromes ◽  
Multicenter Cohort

scholarly journals Consistency of patient-reported outcomes after cholecystectomy and their implications on current surgical practice: a prospective multicenter cohort study

2016 ◽  
Vol 31 (1) ◽  
pp. 215-224 ◽  
Author(s):  
Sarah Wennmacker ◽  
Mark Lamberts ◽  
Jos Gerritsen ◽  
Jan Anne Roukema ◽  
Gert Westert ◽  
...  
Keyword(s):  
Cohort Study ◽  
Patient Reported Outcomes ◽  
Multicenter Cohort Study ◽  
Surgical Practice ◽  
Multicenter Cohort ◽  
Patient Reported

Patient reported outcomes 6 to 12 months after interpersonal violence: A multicenter cohort study

2021 ◽  
Vol 91 (2) ◽  
pp. 260-264
Author(s):  
Manuel Castillo-Angeles ◽  
Juan P. Herrera-Escobar ◽  
Alexander Toppo ◽  
Sabrina E. Sanchez ◽  
Haytham M. Kaafarani ◽  
...  
Keyword(s):  
Cohort Study ◽  
Interpersonal Violence ◽  
Patient Reported Outcomes ◽  
Multicenter Cohort Study ◽  
Multicenter Cohort ◽  
Patient Reported

scholarly journals Predictors of Failure After Surgical Treatment of Femoroacetabular Impingement: Results of a Multicenter Prospective Cohort of 621 Hips

2019 ◽  
Vol 7 (7_suppl5) ◽  
pp. 2325967119S0032
Author(s):  
Jeffrey J. Nepple ◽  
Asheesh Bedi ◽  
Ira Zaltz ◽  
Christopher M. Larson ◽  
Daniel J. Sucato ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Cohort Study ◽  
Surgical Treatment ◽  
Femoroacetabular Impingement ◽  
Revision Surgery ◽  
Patient Reported Outcomes ◽  
Clinical Failure ◽  
Multivariate Logistic Regression ◽  
Multicenter Cohort ◽  
Patient Reported

Objectives: Surgical treatment of femoroacetabular impingement attempts to improve patients’ symptoms through treatment of intra-articular labrochondral pathology and correction of underlying bony deformity. The purpose of the current study was to determine independent predictors of failure after surgical treatment of femoroacetabular impingement in a large prospective multicenter cohort study. Methods: A prospective cohort study of the surgical treatment of FAI was performed. A total of 760 hips undergoing primary surgical treatment of FAI were enrolled across seven surgeons. Patient characteristics, baseline patient reported outcomes (PROs), imaging findings, intraoperative pathology, and surgical treatments were prospectively recorded. A total of 621 hips (81.6%) with minimum one year follow-up were included in the current study (mean 4.3 years). The mHHS was assessed relative to the minimally clinically important difference (MCID, 8 points) and patient acceptable symptom state (PASS, 74 points). Univariate analyses were performed to identify factors significantly associated with failure. Multivariate logistic regression was performed to identify independent predictors of failure. Results: A total of 621 hips undergoing surgical treatment of FAI were assessed at a mean 4.2 years postoperatively. This cohort had a mean age of 29.8 and included 56.8% females. Multivariate logistic regression identified independent predictors of each failure definition. Failure A (THA) was independently associated with increasing age, acetabular microfracture (both p<0.001), and femoral head chondroplasty (p=0.02). Failure B (THA or revision surgery) was independently associated only with lower preoperative mHHS (p<0.001) (p=0.01). A lower failure C (clinical failure) was independently associated with participation in competitive athletics (p=0.01), BMI (p<0.001), and male gender (p<0.001). Conclusion: This large multicenter cohort demonstrates the outcomes of FAI treatment at a mean of 4.3 years postoperative. Rates of THA and revision surgery were 4.0% and 6.9%. An additional 14.8% of patients demonstrates clinical failure based on patient-reported outcomes.

Sign in / Sign up

Export Citation Format

Share Document