Metformin-Associated Lactic Acidosis in Chinese Patients with Type II Diabetes

Pharmacology ◽  
2011 ◽  
Vol 88 (5-6) ◽  
pp. 260-265 ◽  
Author(s):  
Chun Wing Yeung ◽  
Ho Yin Chung ◽  
Bonnie Mei Wah Fong ◽  
Nga Wing Tsai ◽  
Wai Ming Chan ◽  
...  
Keyword(s):  
Lactic Acidosis ◽  
Type Ii Diabetes ◽  
Chinese Patients ◽  
Type Ii

Impact of Japanese regulatory action on metformin-associated lactic acidosis in type II diabetes patients

2015 ◽  
Vol 37 (3) ◽  
pp. 537-545 ◽  
Author(s):  
Tadaaki Hanatani ◽  
Kimie Sai ◽  
Masahiro Tohkin ◽  
Katsunori Segawa ◽  
Yoshiro Saito
Keyword(s):  
Lactic Acidosis ◽  
Type Ii Diabetes ◽  
Regulatory Action ◽  
Type Ii ◽  
Diabetes Patients

scholarly journals Laparoscopic Roux-en-Y Gastric Bypass for the Treatment of Type II Diabetes Mellitus in Chinese Patients with Body Mass Index of 25–35

2011 ◽  
Vol 21 (9) ◽  
pp. 1344-1349 ◽  
Author(s):  
Chih-Kun Huang ◽  
Asim Shabbir ◽  
Chi-Hsien Lo ◽  
Chi-Ming Tai ◽  
Yaw-Sen Chen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Body Mass Index ◽  
Gastric Bypass ◽  
Body Mass ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Chinese Patients ◽  
Type Ii

Dialysis therapy for lactic acidosis caused by metformin intoxication: presentation of two cases

2011 ◽  
Vol 30 (12) ◽  
pp. 1995-1997 ◽  
Author(s):  
Yasemin Usul Soyoral ◽  
Huseyin Begenik ◽  
Habib Emre ◽  
Enver Aytemiz ◽  
Mustafa Ozturk ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Side Effects ◽  
Lactic Acidosis ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
High Dose ◽  
Type Ii ◽  
Dialysis Therapy ◽  
Oral Antidiabetic ◽  
High Doses

Metformin is an oral antidiabetic, which is frequently used in the treatment of type II diabetes mellitus. Serious side effects may be seen during the administration of high doses of metformin. Two cases of lactic acidosis due to ingestion of high dose metformin for suicidal purposes have been presented here; in both cases, clinical improvement was seen with bicarbonate hemodialysis.

scholarly journals β-fibrinogen gene G/A-455 polymorphism in relation to fibrinogen concentrations and ischaemic heart disease in Chinese patients with Type II diabetes

Diabetologia ◽  
1999 ◽  
Vol 42 (10) ◽  
pp. 1250-1253 ◽  
Author(s):  
K. S. L. Lam ◽  
O. C. K. Ma ◽  
N. M. S. Wat ◽  
L. C. Chan ◽  
E. D. Janus
Keyword(s):  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Type Ii Diabetes ◽  
Chinese Patients ◽  
Type Ii

Plasma CTRP-3 concentrations in Chinese patients with obesity and type II diabetes negatively correlate with insulin resistance

2015 ◽  
Vol 9 (3) ◽  
pp. 289-294 ◽  
Author(s):  
Hua Qu ◽  
Min Deng ◽  
Hang Wang ◽  
Huili Wei ◽  
Fang Liu ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Type Ii Diabetes ◽  
Chinese Patients ◽  
Type Ii

scholarly journals Metformin-Induced Lactic Acidosis: A Question of Time

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Céline Bellefroid ◽  
Pierre Goffin ◽  
Julien Guntz ◽  
Marine Deville
Keyword(s):  
Lactic Acidosis ◽  
Type Ii Diabetes ◽  
High Flow ◽  
Type Ii ◽  
Severe Lactic Acidosis ◽  
Oral Antidiabetic ◽  
Metformin Concentration ◽  
Life Threatening

Metformin is an oral antidiabetic largely prescribed in the treatment of type II diabetes. Overdose is associated with life-threatening lactic acidosis. We report the case of the highest metformin concentration ever described secondary to a voluntary suicidal intake. The patient developed a severe lactic acidosis and hemodynamic shock successfully treated with high-flow hemofiltration. Time to start extrarenal epuration is capital to avoid poor evolution.

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