The Relationship between Acidic Urinary pH and Overactive Bladder; Alkalization of Urine Improves the Symptoms of Overactive Bladder

2015 ◽  
Vol 95 (2) ◽  
pp. 223-226 ◽  
Author(s):  
Arif Demirbas ◽  
Hasmet Sarici ◽  
M. Fatih Kilinc ◽  
Onur Telli ◽  
Berat Cem Ozgur ◽  
...  
Keyword(s):  
Overactive Bladder ◽  
Final Analysis ◽  
Diet Therapy ◽  
Control Group ◽  
Urine Ph ◽  
Urinary Ph ◽  
Urinary Tract Symptoms ◽  
Group 2 ◽  
The Relationship ◽  
Acidic Urine

Background: To determine association between urine pH and OAB symptoms and to determine if urinary alkalization improves overactive bladder (OAB) symptoms. Methods: 659 patients with OAB were enrolled in this study between June 2012 and May 2014. 329 patients (group 1) were included in the final analysis. 201 adults were used as a control group (group 2). 24-hour urinary pH and the validated Turkish version of the OAB-V8 questionnaire were performed in patients. A 24-hour urine pH <6.2 was considered acidic urine. In the second part, a diet program was performed for 4 weeks in 30 participants. Urine pH values and OAB-V8 scoring results were recorded before the diet program and 2 and 4 weeks after the diet program. Results: Acidic urinary pH was determined in 61.4% of patients with OAB. There was a significant association between the presence of acidic urine and OAB. Also, the OAB-V8 scores of patients were significantly higher in patients with acidic urine than nonacidic urine. OAB-V8 scores of patients showed statistically significant improvement after diet therapy (17.87 ± 6.52 vs. 10.43 ± 7.17; p < 0.001). Conclusions: We found that acidic urinary pH was closely associated with OAB, and alkalization of urine improved lower urinary tract symptoms. We suggest that urinary pH should be considered as a parameter in treatment planning of patients with OAB.

Comparison of Oral Sodium Bicarbonate and Solifenacin Treatment in Female Overactive Bladder Patients With Acidic Urine pH

2021 ◽  
Vol 76 (1) ◽  
pp. 24-25
Author(s):  
Mehmet Giray Sönmez ◽  
Gökhan Ecer ◽  
Ahmet Atıcı ◽  
Mehmet Serkan Özkent ◽  
Mehmet Sinan İyisoy ◽  
...  
Keyword(s):  
Overactive Bladder ◽  
Sodium Bicarbonate ◽  
Urine Ph ◽  
Oral Sodium ◽  
Acidic Urine

scholarly journals Effectiveness of medical treatment in overcoming the ureteral double-J stent related symptoms

2012 ◽  
Vol 6 (6) ◽  
pp. 234 ◽  
Author(s):  
Ugur Kuyumcuoglu ◽  
Bilal Eryildirim ◽  
Murat Tuncer ◽  
Gokhan Faydaci ◽  
Fatih Tarhan ◽  
...  
Keyword(s):  
The Body ◽  
Control Group ◽  
Group 4 ◽  
Double J Stent ◽  
Urinary Tract Symptoms ◽  
Stone Treatment ◽  
Group 3 ◽  
Group 5 ◽  
Group 2

Background: We investigated whether the frequency of lower urinary tract symptoms (LUTS) increased in patients in whom double-J stents were applied. We also evaluated several medical therapy protocols to treat symptoms related with ureteral stents.Materials and Methods: A total of 108 patients, in whom unilateral double-j stent was applied during ureteral stone treatment, were included. Before the double-J stent was applied, all patients completed storage components of the “International Prostate Symptom Score” (IPSSs), quality of life components of the IPSS (IPSS-QOL) and “Overactive Bladder Questionnaire” (OABq) forms and scores were calculated. After the procedure, cases were randomized into 5 groups, an antiinflammatory was given to Group 1, spasmolytic to Group 2, anticholinergic to Group 3 and α-blocker to Group 4. No additional drug was given to Group 5 as this control group. During the fourth week of the procedure, IPSSs, IPSS-QOL and OABq forms were again completed and scores were compared with the previous ones.Results: When all the cases were evaluated, the IPSSs, IPSS-QOLand OABq scores of patients in whom the double-J stent was applied were statistically significantly higher the procedure. Compared to the control group, the cases where the double-J stent was applied showed a higher IPSSs, IPSS-QOL and OABq scores and none of the medical therapies could prevent this increase.Interpretation: The frequency of LUTS increased in cases where the ureteral stent was applied and discomfort continued as long as the stent stayed in the body.

scholarly journals Study of the effectiveness of supplementary feeding in patients with inherited enzyme deficiency

2019 ◽  
Vol 81 (2) ◽  
pp. 239-244
Author(s):  
L. V. Ulyanova ◽  
V. S. Ledneva ◽  
N. S. Burdina ◽  
M. I. Talykova ◽  
A. S. Ivannikova ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Nutritional Status ◽  
Pancreatic Enzyme ◽  
Diet Therapy ◽  
Enzyme Deficiency ◽  
Control Group ◽  
Anthropometric Parameters ◽  
Group 2 ◽  
The Right ◽  
Supplementary Nutrition

The successful provision of optimal nutrition in children with serious diseases depends on the right diet, as well as the addition of specialized mixtures for its correction. The aim of the study was to study the effectiveness of supplemental nutrition in hereditary fermentopathy (cystic fibrosis) in children. The work included a three-year follow-up of 69 children aged 3 to 15 years suffering from cystic fibrosis. Patients were divided into two groups: 37 patients with cystic fibrosis group 1, receiving a modified version of treatment with additional enteral nutrition and 32 patients with cystic fibrosis group 2, receiving traditional treatment. The study conducted a comparative analysis of changes in trophic status in patients using nutritional support mixture produced in the Russian Federation – "Nutrien-standard"in diet therapy. Laboratory, functional and anthropometric parameters were monitored once a month. A significant increase in the physical development of patients was obtained only in the second year of use in the diet of supplementary nutrition, p<0.05. At the 3rd year of treatment, the results of positive dynamics of nutritional status in both groups were confirmed, while the increase in body mass index in the main group was 6.7%, and in the control group-only 1% (p<0.05). It is noted that the use of this mixture allows to achieve positive dynamics of nutritional status in 27% of patients and in 73% of cases to completely eliminate it. The obtained results prove the expediency of additional use of "Nutrient-standard" mixture in the complex therapy of patients with hereditary pancreatic enzyme deficiency, cystic fibrosis

scholarly journals Body composition and lung function in adults with Cystic Fibrosis

2020 ◽  
Vol 83 (3) ◽  
pp. 239-250
Author(s):  
Aleksandra John ◽  
Joanna Goździk-Spychalska ◽  
Magdalena Durda-Masny ◽  
Wojciech Czaiński ◽  
Marta Gębala ◽  
...  
Keyword(s):  
Body Composition ◽  
Lung Function ◽  
Nutritional Status ◽  
Reference Group ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Control Group ◽  
Body Components ◽  
Group 2 ◽  
The Relationship

AbstractThe study aimed to assess: (1) differences in nutritional status and lung function between CF patients and the control group; (2) differences in body composition and lung function between groups of patients with CF designated by type of mutation; (3) the relationship between lung function and body composition in CF patients.We studied 37 CF patients aged 19 to 51 years, and 41 healthy non-CF volunteers. Nutritional status was evaluated based on the BMI and the bioelectrical impedance analysis. The lung function was described by FEV1%. CF patients were classified according to the CFTR genotype based on five classes of mutations. BMI were lower in CF patients compared to reference group (women: Z = 3.76, p <0.001, men: Z = 3.06, p = 0.002). CF patients had a lower mean content of particular body components, as well as FEV1% values. BMI differed significantly depending on the type of mutation in females (H = 10.33, p = 0.006) and males (H = 8.26, p = 0.016). The lowest values of BMI were observed in the group of patients with severe types of mutations. Also, variables describing body composition were statistically significantly lower in patients with a severe type of mutations. The CFTR gene mutation type statistically significantly differentiated FEV1% (H = 23.22, p <0.000). The results of the logistic regression analysis showed that the likelihood of dropping FEV1% below the norm was twice as high in undernourished females and males. To assess the nutritional status of CF patients, more informative methods describing the proportions of body components are required.

scholarly journals A Strategic Approach to Implementation of Medical Mentorship Programs

2016 ◽  
Vol 8 (1) ◽  
pp. 68-73 ◽  
Author(s):  
Thomas J. Caruso ◽  
Diane H. Steinberg ◽  
Nancy Piro ◽  
Kimberly Walker ◽  
Rebecca Blankenburg ◽  
...  
Keyword(s):  
Training Programs ◽  
Psychosocial Support ◽  
Control Group ◽  
Chi Square ◽  
Mentorship Program ◽  
Professional Aspirations ◽  
Group 2 ◽  
Survey Responses ◽  
The Relationship ◽  
Group 1

ABSTRACT Background Mentors influence medical trainees' experiences through career enhancement and psychosocial support, yet some trainees never receive benefits from involved mentors. Objective Our goals were to examine the effectiveness of 2 interventions aimed at increasing the number of mentors in training programs, and to assess group differences in mentor effectiveness, the relationship between trainees' satisfaction with their programs given the presence of mentors, and the relationship between the number of trainees with mentors and postgraduate year (PGY). Methods In group 1, a physician adviser funded by the graduate medical education department implemented mentorships in 6 residency programs, while group 2 involved a training program with funded physician mentoring time. The remaining 89 training programs served as controls. Chi-square tests were used to determine differences. Results Survey responses from group 1, group 2, and controls were 47 of 84 (56%), 34 of 78 (44%), and 471 of 981 (48%, P = .38), respectively. The percentages of trainees reporting a mentor in group 1, group 2, and the control group were 89%, 97%, and 79%, respectively (P = .01). There were no differences in mentor effectiveness between groups. Mentored trainees were more likely to be satisfied with their programs (P = .01) and to report that faculty supported their professional aspirations (P = .001). Across all programs, fewer first-year trainees (59%) identified a mentor compared to PGY-2 through PGY-8 trainees (84%, P &lt; .001). Conclusions A supported mentorship program is an effective way to create an educational environment that maximizes trainees' perceptions of mentorship and satisfaction with their training programs.

scholarly journals Assessment of Corneal Biomechanical Properties and Intraocular Pressure in Myopic Spanish Healthy Population

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
María A. del Buey ◽  
Laura Lavilla ◽  
Francisco J. Ascaso ◽  
Elena Lanchares ◽  
Valentín Huerva ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
High Myopia ◽  
Biomechanical Properties ◽  
Control Group ◽  
Healthy Population ◽  
Iop Measurement ◽  
Group 3 ◽  
Biomechanical Parameters ◽  
Group 2 ◽  
The Relationship

Purpose. To examine biomechanical parameters of the cornea in myopic eyes and their relationship with the degree of myopia in a western healthy population.Methods. Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann correlated intraocular pressure (IOP), and corneal compensated IOP (IOPcc) were measured using the ocular response analyzer (ORA) in 312 eyes of 177 Spanish subjects aged between 20 and 56 years. Refraction was expressed as spherical equivalent (SE), which ranged from 0 to −16.50 diopters (D) (mean:−3.88±2.90 D). Subjects were divided into four groups according to their refractive status: group 1 or control group: emmetropia (-0.50≤SE<0.50); group 2: low myopia (-0.75≤SE<3.00 D); group 3: moderate myopia (-3.00≤SE≤-6.00 D); and group 3: high myopia (SE greater than −6.00 D). We analyzed the relationship between corneal biomechanics measured with ORA and SE.Results. CH in the emmetropia, low myopia, moderate myopia, and high myopia groups was11.13±0.98,11.49±1.25,10.52±1.54, and10.35±1.33 mmHg, respectively. CH in the highly myopic group was significantly lower than that in the emmetropic group (P=0.07) and low myopic group (P=0.035); however, there were no differences with the moderate myopic group (P=0.872). There were no statistically significant differences regarding IOP among the four groups (P>0.05); nevertheless, IOPcc was significantly higher in the moderately myopic (15.47±2.47 mmHg) and highly myopic (16.14±2.59 mmHg) groups than in the emmetropia (15.15±2.06 mmHg) and low myopia groups (14.53±2.37 mmHg). No correlation between age and the measured parameters was found. CH and IOPcc were weakly but significantly correlated with SE (r=0.171,P=0.002andr=-0.131,P=0.021, resp.).Conclusions. Present study showed only a very weak, but significant, correlation between CH and refractive error, with CH being lower in both moderately and highly myopic eyes than that in the emmetropic and low myopic eyes. These changes in biomechanical properties of the cornea may have an impact on IOP measurement, increasing the risk of glaucoma.

EFFECT OF COMBINATED APPLICATION OF PROBIOTIC AND ENTEROSORBENT ON THE DYNAMICS OF CORTISOL IN CHICKENS IN THE EARLY POSTEMBRIONIC PERIOD

2020 ◽  
Keyword(s):  
Marked Reduction ◽  
Marked Decrease ◽  
Early Stage ◽  
Relative Increase ◽  
Stress Factors ◽  
Control Group ◽  
Group A ◽  
Group 2 ◽  
Stable Growth ◽  
The Relationship

The research is devoted to the study of chickens’ cortisol dynamics at an early stage ofpost-embryonic development with the use of probiotics such as zoonorm, enterosorbent based on polymethylsilxane polyhydrate and their complex. To achieve the goal, 4 groups of analogue chickens were formed, 1 was a control group, 2 - received a probiotic in a mixture with feed at a dose of 0.2 g per head in morning feeding; 3 - 0.3% weight enterosorbent 2 hours after evening feeding; 4 - a combination of two preparations at the appropriate time. The introduction of drugs was carried out from 5- to 25-day age. All the indicators were analyzed in 5-, 15-, 25- and 35-day chicks. As a result of the research, chicks in all groups showed an increase in cortisol concentrations. In the control group a stable growth of the indicator was observed, which reached a maximum in 35 days, an increase in the concentration of the hormone by 41.6% was accompanied by an increase in glucose to 14.6 to 0.5 mmol/L, a decrease in cholesterol and triglycerides. In chicks 2 and 3 groups the highest value of cortisol is noted in 25 days, 4 - in 15 days. In 2 and 3 groups, with maximum cortisol levels, glucose concentrations were 14.64 and 14.91 mmol/L, with a marked decrease in triglycerides and cholesterol. In the 4th group of 15-day-old chicks, an 8.4% increase in cholesterol and triglycerides resulted in a 37.3 and 68.9% decrease in cholesterol and triglycerides. At the end of the experiment, the 4th group was found to reduce cortisol to 5.07 nmol/L, glucose to 12.32 to 0.13 mmol/L, and a relative increase in triglycerides. In conclusion, the relationship between synthesis of cortisol, cholesterol, triglycerides, glucose and their metabolism was confirmed. There has been a marked reduction in the influence of stress factors and increased resistance of chickens with the complex use of probiotic and enterosorbent.

Comparison of Oral Sodium Bicarbonate and Solifenacin Treatment in Female Overactive Bladder Patients With Acidic Urine pH

2018 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Mehmet Giray Sönmez ◽  
Gökhan Ecer ◽  
Ahmet Atici ◽  
Mehmet Serkan Özkent ◽  
Mehmet Sinan İyisoy ◽  
...  
Keyword(s):  
Overactive Bladder ◽  
Sodium Bicarbonate ◽  
Urine Ph ◽  
Oral Sodium ◽  
Acidic Urine

scholarly journals Relationship between lower urinary tract symptoms and inguinal hernia

2016 ◽  
Vol 88 (4) ◽  
pp. 262
Author(s):  
Aykut Buğra Sentürk ◽  
Musa Ekici ◽  
Ibrahim Tayfun Sahiner ◽  
Tuncay Tas ◽  
Basri Cakiroglu
Keyword(s):  
Inguinal Hernia ◽  
Urinary Tract ◽  
Indirect Inguinal Hernia ◽  
Chi Square ◽  
Prostate Hyperplasia ◽  
Direct Inguinal Hernia ◽  
Urinary Tract Symptoms ◽  
Group 2 ◽  
Chi Square Analysis ◽  
The Relationship

Aim: To determine the relationship between inguinal hernia (and inguinal hernia subtypes) and low urinary tract symptoms (LUTS) due to benign prostate hyperplasia (BPH), that could be more common than we think. Method: The study was designed retrospectively and was done in accordance with the principles of the Declaration of Helsinki, including 100 patients aged &gt; 50 years that were divided into 2 groups: patients with BPH (BPH group) and patients with BPH and inguinal hernia (BPH-IH group 2). In addition, the BPH-IH group was subdivided according to 2 inguinal hernia subtypes; patients of BPH-IH subgroup A had direct inguinal hernia (n = 25) and those of BPH-IH subgroup B had indirect inguinal hernia (n = 25). Results: There was no statistical relationship and difference in rates between IPSS scores in both groups (p = 0.659) and there wasn’t a significant correlation between IPSS symptom severity and type of hernia, based on chi square analysis (p = 0.104) Conclusion: We were not able to prove our hypothesis that patients with inguinal hernia and BPH would have higher IPSS scores because of voiding dysfunction.

Effects of Balance Training on Postural Stability

2002 ◽  
Vol 46 (13) ◽  
pp. 1237-1240
Author(s):  
Jennifer M. Schmit ◽  
Deanna I. Rejacques ◽  
Michael A. Riley
Keyword(s):  
Postural Control ◽  
Postural Sway ◽  
Balance Training ◽  
Control Group ◽  
Significant Group ◽  
Eyes Closed ◽  
Eyes Open ◽  
Group 2 ◽  
Main Effects ◽  
The Relationship

The present study is designed to address the relationship between postural sway and balance training. We compared postural sway in a group of trained dancers to a group of physically fit, untrained participants (control group) in order to assess enhanced postural control with balance training, particularly under challenging balance conditions. We varied the difficulty of postural control by using two surface conditions (rigid surface, foam surface) and two visual conditions (eyes open, eyes closed), factorially combined. The data were evaluated using 1-between (group) × 2-within (vision and surface) analyses of variance (ANOVA). The three dependent variables were the standard deviation of the COP time series in the anterior-posterior (AP) and medial-lateral (ML) axes, and the COP path length. Significant main effects were found for surface and vision and the surface*vision interaction in all conditions. Significant group differences were found in the AP and ML axes. The results of this study indicate that balance training enhances the control of posture. Thus, it may be useful to provide balance training to workers who must operate under conditions that threaten balance.

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