scholarly journals Causes of Death Data in the Global Burden of Disease Estimates for Ischemic and Hemorrhagic Stroke

2015 ◽  
Vol 45 (3) ◽  
pp. 152-160 ◽  
Author(s):  
Thomas Truelsen ◽  
Lars-Henrik Krarup ◽  
Helle K. Iversen ◽  
George A. Mensah ◽  
Valery L. Feigin ◽  
...  
Keyword(s):  
Literature Review ◽  
Burden Of Disease ◽  
Causes Of Death ◽  
Hemorrhagic Stroke ◽  
Age Groups ◽  
Global Burden Of Disease ◽  
Mortality Data ◽  
Global Burden ◽  
Stroke Mortality ◽  
Mortality Estimates

Background: Stroke mortality estimates in the Global Burden of Disease (GBD) study are based on routine mortality statistics and redistribution of ill-defined codes that cannot be a cause of death, the so-called ‘garbage codes' (GCs). This study describes the contribution of these codes to stroke mortality estimates. Methods: All available mortality data were compiled and non-specific cause codes were redistributed based on literature review and statistical methods. Ill-defined codes were redistributed to their specific cause of disease by age, sex, country and year. The reassignment was done based on the International Classification of Diseases and the pathology behind each code by checking multiple causes of death and literature review. Results: Unspecified stroke and primary and secondary hypertension are leading contributing ‘GCs' to stroke mortality estimates for hemorrhagic stroke (HS) and ischemic stroke (IS). There were marked differences in the fraction of death assigned to IS and HS for unspecified stroke and hypertension between GBD regions and between age groups. Conclusions: A large proportion of stroke fatalities are derived from the redistribution of ‘unspecified stroke' and ‘hypertension' with marked regional differences. Future advancements in stroke certification, data collections and statistical analyses may improve the estimation of the global stroke burden.

Incidence Trends of Lip, Oral Cavity, and Pharyngeal Cancers: Global Burden of Disease 1990–2017

2019 ◽  
Vol 99 (2) ◽  
pp. 143-151 ◽  
Author(s):  
M. Du ◽  
R. Nair ◽  
L. Jamieson ◽  
Z. Liu ◽  
P. Bi
Keyword(s):  
Oral Cavity ◽  
Burden Of Disease ◽  
Age Groups ◽  
Global Burden Of Disease ◽  
Mortality Data ◽  
Global Burden ◽  
Middle Income ◽  
Incidence Trends ◽  
Oral Cavity Cancers ◽  
Incident Cases

The worldwide incidence trends of the lip, oral cavity, and pharyngeal cancers (LOCPs) need to be updated. This study aims to examine the temporal incidence trends of LOCPs from 1990 to 2017, using the latest Global Burden of Disease (GBD) study data to explore sex, age, and regional differences. GBD incidence data for LOCPs were driven by population cancer registries and were estimated from mortality data. Age-standardized incidence rates (ASIRs) were directly extracted from the 2017 GBD database to calculate the estimated annual percentage change (EAPC) over the study period. Incidence trends are mapped and compared separately by sex (females vs. males), age groups (15–49, 50–69, and 70+ y), regions (21 geographical and 5 sociodemographic regions), and countries. Among 678,900 incident cases of LOCPs notified in 2017, more than half were lip and oral cavity cancers. From 1990 to 2017, the estimated global incidence for nasopharyngeal cancers decreased dramatically (EAPC = −1.52; 95% confidence interval [CI], –1.70 to −1.34), while the incidence for lip and oral cavity cancers (EAPC = 0.26; 95% CI, 0.16–0.37) and other pharyngeal cancers (EAPC = 0.62; 95% CI, 0.54–0.71) increased. Higher ASIRs were observed among males than females across all age groups. However, females had larger EAPC variation when compared to males. Population groups aged 15 to 49 y presented the lowest ASIRs, with larger values of EAPC than those aged 50 to 69 and 70+ y. While high-income countries had higher ASIRs with little EAPC variation, ASIRs varied across low/middle-income regions with larger EAPC variations. South Asia and East Asia had the highest ASIRs and EAPC for lip and oral cavity cancers, respectively. In conclusion, the global incidence of LOCPs has increased among females, those aged 15 to 49 y, and people from low/middle-income countries over the study period, excepting nasopharyngeal cancers, which had a decreasing worldwide trend.

scholarly journals Topic: Under-5 children mortality in Chad from 1990 to 2017: Analysis of the Global Burden of Disease data

2019 ◽  
Author(s):  
NODJIMADJI TAMLENGAR MARTIAL ◽  
YU Chuanhua
Keyword(s):  
Sustainable Development ◽  
United Nations ◽  
Burden Of Disease ◽  
Sustainable Development Goals ◽  
Age Groups ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Neonatal Group ◽  
Development Goals ◽  
The United Nations

Abstract Background: Ending preventable death for newborns and children is one of the new goals set by the United Nations as the Sustainable Development Goals (SDGs). This goal should be reached by the year of 2030, in all United Nations countries including the Republic of Chad. Chad is one of the Sub-Saharan countries in central Africa, where infants’ mortality is still high, due to many conditions. The objective of this study is to analyze the mortality in under-5 children in Chad from 1990-2018, with data from the Global Burden of Disease (GBD). Methods: Data from GBD (GHDx input source) of under-5 mortality in Chad 1990-2018 was analyzed using IBM SPSS Statistics version 25 by performing a Two-way ANOVA to check for the interaction effect between gender, age, and mortality. A Mean compare was used to determine the most involved gender and the most involved age in under-5 mortality in Chad. Results: The male gender 12510 (95%CI -4867-29888 52%) is higher than the female gender 11401 (95%CI -5976-28779 48%) in under-5 mortality in Chad from 1990-2018. This can also be interpreted by the percentages of YLLs in both genders with the male’s 1085166 (95%CI 1067788-1102544 52%) which is also higher than the female’s 988032 (95%CI 970654-1005410 48%). In the different age groups used in this study, the overall Data showed that the 1-4years age group is the most affected with a highest number (Deaths and YLLs) 717547 (45.6%), followed by the Post neonatal group 552360 (35.1%), and finally the Early neonatal group 302924 (19.3%). Conclusion: Under-5 mortality in Chad is still higher compared to the new Sustainable Development Goals set by the United Nations.

The trend of incidence and burden of neurological disease in Iran between 1990 and 2017: Based on global burden of disease estimations

2019 ◽  
Author(s):  
Hedayat Abbastabar ◽  
Sama Bitarafan ◽  
Mohammad Hossein Harirchian
Keyword(s):  
Burden Of Disease ◽  
Neurological Disease ◽  
Neurological Diseases ◽  
Age Groups ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Disability Adjusted Life Years ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Increasing Trend

Neurological disease contributes significantly to morbidity and mortality in different ages and geographic areas around the world. The purpose of the current study was to investigate the incidence and disability-adjusted life years (DALYs) trend of neurological disease in Iran during 27 years ago. We used the data of the Global Burden of Disease (GBD) Study to estimate the incidence and DALYs of neurological disease in Iran in different age groups between 1990 and 2017. Age groups were defined in 5 groups including < 5 years, 5-14 years, 15-49 years, 50-69 years, and ≥ 70 years. The incidence number of neurological disease during 1990 to 2017 increased from 7.5 million to more than 12 million and the incidence rate grew as much as 1400 per 100000 populations in Iran. Totally, headache, epilepsy, and Alzheimer were the most common neurological diseases according to incidence and had the most values of DALY in Iran. The highest incidence and DALY of neurological disease was observed in the age group of 15-49 years. This study showed that the incidence and burden of neurological diseases had a dramatic increasing trend during 27 years ago in Iran. Consequently, it is necessary to investigate the causes of the growing trend in future studies. 

scholarly journals The Burden of Childhood Asthma by Age Group, 1990-2019: A Systematic Analysis for Global Burden of Disease Study 2019 Data

2021 ◽  
Author(s):  
ZHANG DAOQI ◽  
Jinxin Zheng
Keyword(s):  
Burden Of Disease ◽  
Childhood Asthma ◽  
Age Groups ◽  
High Body Mass Index ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Age Group ◽  
Systematic Analysis ◽  
Life Years ◽  
Asthma Prevention

Abstract Background: Asthma is a common respiratory disease in children. We aimed to update information about incidence of and mortality and disability adjusted life years (DALYs) due to childhood asthma and provide evidence-based recommendations for childhood asthma prevention.Methods Data were obtained from the Global Burden of Disease (GBD) Study, which was conducted from 1990 to 2019 in 204 countries. First, we estimated the incidence, mortality and DALY rates of childhood asthma with a Bayesian meta-regression model. Second, we analyzed the relationship between the sociodemographic index (SDI) and DALYs in different age groups. Third, we studied changes in the trends of the age-standardized DALY rate between 1990 and 2019 by age group, SDI, and risk factors.Results Globally, the numbers of deaths due to and the incidence and DALY rates of childhood asthma were 12.9 thousand (95% UI 10.6 to 15.7), 22 million (95% UI 15 to 31), and 5.1 million (95% UI 3.4 to 7.5) in 2019, representing 65.1% (95% UI 47.6 to 72.4), 5.3% (95% UI 2.6 to 8.8) and 30% (95% UI 18 to 41) decreases from those in 1990, respectively. With the exception of high-SDI regions, the age-standardized DALY rate in all age groups in all SDI regions decreased. In 2019, the age-standardized DALY rate in 1- to 4-year-olds was highest in low-SDI regions, and that of 5- to 19-year-olds was highest in high-SDI regions. In contrast to those in low-SDI regions, children, except those aged 1 to 4 years, in high-SDI regions had a higher risk of DALYs due to asthma. A high body mass index was a stronger risk factor than occupational asthmagens for childhood asthma.Conclusion Our findings provide insights into asthma prevention and treatment through the identification of key factors related to childhood asthma. Children, especially those aged 5 to 14 years, in high-SDI regions should change their eating and lifestyle habits and exercise regularly. Data on additional chronic diseases in children need to be collected to develop better health prevention recommendations.

Trends in drowning mortality in Portugal from 1992 to 2019: comparing Global Burden of Disease and national data

2021 ◽  
pp. injuryprev-2021-044415
Author(s):  
Ana Catarina Queiroga ◽  
Rui Seabra ◽  
Richard Charles Franklin ◽  
Amy E Peden
Keyword(s):  
Burden Of Disease ◽  
International Classification Of Diseases ◽  
Global Burden Of Disease ◽  
Mortality Data ◽  
Global Burden ◽  
Data Systems ◽  
Water Safety ◽  
National Data ◽  
Depth Analysis ◽  
Icd 10

IntroductionImprecise data systems hinder understanding of drowning burden, even in high-income countries like Portugal, that have a well-implemented death certificate system. Consequently, national studies on drowning mortality are scarce. We aimed to explore drowning mortality in Portugal using national data and to compare these to Global Burden of Disease (GBD) estimates.MethodsData were obtained from the National Institute of Statistics (INE) for 1992–2019, using International Classification of Diseases (ICD)-9 and ICD-10 codes, by sex, age group and cause (unintentional; water transport and intentional). GBD unintentional drowning data were obtained online. Age-standardised drowning rates were calculated and compared.ResultsINE data showed 6057 drowning deaths, 4327 classified as unintentional (75.2% male; 36.7% 35–64 years; 31.5% 65+years; 15.2% 0–19 years). Following 2001, an increase in accidental drowning mortality and corresponding decrease in undetermined intent was observed, coincident with Portugal’s ICD-10 implementation. GBD modelled estimates followed a downward trend at an overall rate of decrease of −0.41/decade (95% CI (−0.45 to –0.37); R2adj=0.94; p<0.05). Conversely, INE data showed an increase in the rate of drowning deaths over the last decade (0.35/decade; 95% CI (−0.18 to 0.89)). GBD estimates were significantly different from the INE dataset (alpha=0.05), either underestimating as much as 0.567*INE in 1996 or overestimating as much as 1.473*INE in 2011.ConclusionsWhile GBD mortality data estimates are valuable in the absence of routinely collected data, they smooth variations, concealing key advocacy opportunities. Investment in country-level drowning registries enables in-depth analysis of incident circumstances. Such data are essential to informing National Water Safety Plans.

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