scholarly journals Acute Macular Neuroretinopathy following Oral Intake of Adrenergic Flu Treatments

2018 ◽  
Vol 9 (2) ◽  
pp. 322-326 ◽  
Author(s):  
Dinu Stanescu-Segall ◽  
Chong Yap ◽  
Ben J.L. Burton
Keyword(s):  
Young Patient ◽  
Case Series ◽  
Oral Intake ◽  
Case Review ◽  
Adrenergic Stimulation ◽  
Retrospective Case ◽  
Loss Of Vision ◽  
Acute Macular Neuroretinopathy

Purpose: The purpose of this study was to report a case series of patients with acute macular neureretinopathy in which patients concomitantly used ephedrine or pseudo-ephedrine. Methods: This is a retrospective case review. Results: Two patients with retinal findings consistent with acute macular neuroretinopathy are presented. Conclusion: Acute macular neuroretinopathy should be considered in any young patient with unexplained loss of vision and exposed to direct or indirect adrenergic stimulation.

Ewing’s Sarcoma of the Hand

2008 ◽  
Vol 34 (1) ◽  
pp. 35-39 ◽  
Author(s):  
O. A. ANAKWENZE ◽  
W. L. PARKER ◽  
L. E. WOLD ◽  
K. K AMRAMI ◽  
P. C. AMADIO
Keyword(s):  
Radiation Therapy ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Case Series ◽  
Surgical Excision ◽  
Case Review ◽  
Retrospective Case ◽  
Postoperative Radiation Therapy ◽  
Definitive Surgery

A retrospective case review was carried out to report the outcomes in a contemporary case series of Ewing’s sarcoma originating in the hand. We identified five patients treated since 1995. All five had wide surgical excision, one by ray amputation. All were treated with chemotherapy. Four patients also received radiation therapy, two to treat metastases and two as an adjunct to local excision. There were no local recurrences. Two patients developed metastases. Both died of their disease. Neither of these two patients had received local postoperative radiation therapy; one did not receive chemotherapy before definitive surgery. The other three patients were alive and free of disease at last follow-up, 4 to 12 years after initial presentation.

scholarly journals Magnetic resonance imaging of traumatic injury to the craniovertebral junction: a case-based review

2015 ◽  
Vol 38 (4) ◽  
pp. E3 ◽  
Author(s):  
Anil K. Roy ◽  
_ _ ◽  
Brandon A. Miller ◽  
Christopher M. Holland ◽  
Arthur J. Fountain ◽  
...  
Keyword(s):  
Clinical Judgment ◽  
Clinical Decision Making ◽  
Spinal Column ◽  
Case Series ◽  
Craniovertebral Junction ◽  
Significant Heterogeneity ◽  
Case Review ◽  
Ligamentous Injury ◽  
Mri Findings ◽  
Retrospective Case

OBJECT The craniovertebral junction (CVJ) is unique in the spinal column regarding the degree of multiplanar mobility allowed by its bony articulations. A network of ligamentous attachments provides stability to this junction. Although ligamentous injury can be inferred on CT scans through the utilization of craniometric measurements, the disruption of these ligaments can only be visualized directly with MRI. Here, the authors review the current literature on MRI evaluation of the CVJ following trauma and present several illustrative cases to highlight the utility and limitations of craniometric measures in the context of ligamentous injury at the CVJ. METHODS A retrospective case review was conducted to identify patients with cervical spine trauma who underwent cervical MRI and subsequently required occipitocervical or atlantoaxial fusion. Craniometric measurements were performed on the CT images in these cases. An extensive PubMed/MEDLINE literature search was conducted to identify publications regarding the use of MRI in the evaluation of patients with CVJ trauma. RESULTS The authors identified 8 cases in which cervical MRI was performed prior to operative stabilization of the CVJ. Craniometric measures did not reliably rule out ligamentous injury, and there was significant heterogeneity in the reliability of different craniometric measurements. A review of the literature revealed several case series and descriptive studies addressing MRI in CVJ trauma. Three papers reported the inadequacy of the historical Traynelis system for identifying atlantooccipital dislocation and presented 3 alternative classification schemes with emphasis on MRI findings. CONCLUSIONS Recognition of ligamentous instability at the CVJ is critical in directing clinical decision making regarding surgical stabilization. Craniometric measures appear unreliable, and CT alone is unable to provide direct visualization of ligamentous injury. Therefore, while the decision to obtain MR images in CVJ trauma is largely based on clinical judgment with craniometric measures used as an adjunct, a high degree of suspicion is warranted in the care of these patients as a missed ligamentous injury can have devastating consequences.

The Sternocleidomastoid Myocutaneous Flap: A Laryngeal Preservation Option for Total Hypopharyngoesophageal Stenosis

2019 ◽  
Vol 161 (1) ◽  
pp. 186-189 ◽  
Author(s):  
Hassan Paknezhad ◽  
Nicole A. Borchard ◽  
Gordon K. Lee ◽  
Edward J. Damrose
Keyword(s):  
Donor Site ◽  
Case Series ◽  
Oral Intake ◽  
Donor Site Morbidity ◽  
Retrospective Case ◽  
Endoscopic Techniques ◽  
Laryngeal Preservation ◽  
Cosmetic Outcomes ◽  
Surgical Field ◽  
Pharyngeal Reconstruction

Complete hypopharyngoesophageal (HPE) stenosis is rare and a challenging condition to treat. When endoscopic therapy fails, total laryngectomy with or without pharyngeal reconstruction is usually performed. We present a retrospective case series involving 3 patients with complete HPE stenosis who failed endoscopic repair and were gastrostomy dependent. All were managed successfully with the sternocleidomastoid myocutaneous (SCM) flap. A temporary fistula occurred in 1 patient. Hospitalization ranged from 5 to 15 days, patients resumed oral intake from 21 to 82 days postoperatively, and their gastrostomy tubes were removed from 28 to 165 days postoperatively. We suggest that the SCM flap is a laryngeal preservation option for reconstruction of complete HPE stenosis when endoscopic techniques fail. This flap allows HPE repair and reconstruction within the same surgical field, imposes no significant donor site morbidity, and affords good functional and cosmetic outcomes.

Defining failure after parathyroidectomy for primary hyperparathyroidism: case series

2011 ◽  
Vol 125 (4) ◽  
pp. 394-398
Author(s):  
S D Charlett ◽  
M Aye ◽  
S L Atkin ◽  
R J A England
Keyword(s):  
Primary Hyperparathyroidism ◽  
Outcome Measure ◽  
Case Series ◽  
Case Review ◽  
Cure Rate ◽  
Retrospective Case ◽  
Diagnostic Uncertainty ◽  
Primary Surgery ◽  
Primary Procedure ◽  
Cause Of Failure

AbstractObjective:To identify the cause of operative failure in patients who have undergone parathyroid surgery for primary hyperparathyroidism.Design:Retrospective case review.Participants:Patients who had undergone a primary procedure for primary hyperparathyroidism between July 2003 and December 2007. Cases with incomplete post-operative serum calcium data were excluded.Main outcome measure:Operative failure was defined as failure to achieve normalisation of serum adjusted calcium levels post-operatively.Results:A total of 220 primary procedures were conducted over 4.5 years. Data were not available for 16 patients. Thirteen procedures (6.4 per cent) were considered failures, and these cases were individually reviewed and classified according to the reason for failure.Conclusion:Establishing the cause of failure following surgery for primary hyperparathyroidism can be a complex task. In some instances, diagnostic uncertainty remains despite detailed biochemical and radiological assessment. This paper outlines our approach to maximising the cure rate at primary surgery.

Causative agents of liver abscess in HIV-seropositive patients: a 10-year case series in Thai hospitalized patients

2005 ◽  
Vol 35 (2) ◽  
pp. 115-115 ◽  
Author(s):  
Viroj Wiwanitkit
Keyword(s):  
Liver Abscess ◽  
Case Series ◽  
Gastrointestinal Disorder ◽  
High Rate ◽  
Amoebic Liver Abscess ◽  
Case Review ◽  
Retrospective Case ◽  
Gram Negative ◽  
Positive Bacterial Culture ◽  
Hiv Seropositive

Liver abscess is an important tropical gastrointestinal disorder. HIV seropositive patients show relative immunosuppression and are more susceptible to infection, including liver abscess. This retrospective case review was made on 23 patients who were diagnosed as HIV seropositive with liver abscess in Bangkok, Thailand. We demonstrated the high rate of amoebic liver abscess in our series (17.4%) from fresh smear with five cases of tuberculosis and one case of Nocardosis. The rates of positive bacterial culture were 17.4% from blood and 47.8% from pus. Gram-negative aerobes were the major abscess pathogens in our series. Among Gram-negative aerobes, Klebsiella was the most significant microorganism, followed by Escherichia coli and Pseudomonas aeruginosa.

Malignant otitis externa: case series

2010 ◽  
Vol 124 (8) ◽  
pp. 846-851 ◽  
Author(s):  
T Ali ◽  
K Meade ◽  
S Anari ◽  
M R ElBadawey ◽  
I Zammit-Maempel
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Cranial Nerve ◽  
Cranial Nerve Palsy ◽  
Otitis Externa ◽  
Nerve Palsy ◽  
Case Series ◽  
Case Review ◽  
Retrospective Case ◽  
North East ◽  
Malignant Otitis Externa

AbstractBackground:In the light of current concerns regarding ciprofloxacin resistance and the changing face of malignant otitis externa, we reviewed cases of malignant otitis externa treated in our centre, in order both to evaluate the current epidemiology of the condition and to assess the status of drug resistance in our patient population.Method:Retrospective case review of all malignant otitis externa cases managed in a tertiary referral centre in the north-east of England between 2000 and 2009.Results:Forty-one patients were identified, but the required data were available for only 37 cases. Patients' ages ranged from 51 to 101 years (median, 81 years). Diabetes was present in 51 per cent of patients (19/37), facial nerve palsy in 40 per cent (15/37) and multiple cranial nerve palsy in 24 per cent (9/37). Pseudomonas aeruginosa was the most commonly isolated organism (54 per cent), sensitive to ciprofloxacin in all cases.Conclusions:The incidence of cranial nerve palsy in our study was higher than in previous reports. The incidence of diabetes and Pseudomonas aeruginosa in our cohort was much lower than previously reported. The Pseudomonas aeruginosa strains isolated were all sensitive to ciprofloxacin, despite recent reports on emerging resistance.

scholarly journals A.05 An epidemiologic study of SLC52A2-related Riboflavin Transport Deficiency

2017 ◽  
Vol 44 (S2) ◽  
pp. S9-S10
Author(s):  
JK Mah ◽  
M Menezes ◽  
K Massey
Keyword(s):  
Neurodegenerative Disorder ◽  
Early Recognition ◽  
Epidemiologic Study ◽  
Case Series ◽  
High Dose ◽  
Case Review ◽  
Retrospective Case ◽  
Limb Weakness ◽  
Presenting Symptoms ◽  
Transporter Deficiency

Background: Riboflavin transporter deficiency (RTD), formerly known as Brown-Vialetto-van Laere syndrome, is an early-onset neurodegenerative disorder with distinctive phenotypes. RTD is caused by mutations in either the SLC52A2 or SLC52A3 genes that encode riboflavin transporters RFVT-2 and RFVT-3, respectively. Methods: This was a 3-year retrospective case review from the Cure RTD International Registry. Results: 73 individuals (~60% female, 14 deceased) from 56 families had genetically confirmed RTD Type 2, including 30 novel SLC52A2 mutations (24 missense, 2 nonsense, 4 deletion). The mean ages at symptom onset and at diagnosis were 2.4 years (SD 1.5, range 0.25–8, n=63) and 12.0 years (SD 10.2, range 0.75–52, n=56) respectively. Most common presenting symptoms were sensory ataxia (n=43), sensorineural hearing loss (n=22), nystagmus/visual loss secondary to optic atrophy (n=14), upper limb weakness (n=11), and respiratory insufficiency (n=9). Treatment included high dose riboflavin, other supplements, and supportive care; 7 individuals required transfusions for anemia pre-riboflavin treatment and 17 (25%) received a cochlear implant. The minimum prevalence of RTD was estimated to be 1 per million, with >100 new cases each year. Conclusions: This is the largest case series of RTD to date. Early recognition and prompt riboflavin treatment is essential for survival and optimal outcome.

scholarly journals Beware of the Migrating Chest Pain and Widened Mediastinum: Case Series on Aortic Dissection

2002 ◽  
Vol 9 (2) ◽  
pp. 95-101
Author(s):  
CH Chung ◽  
KK Lai
Keyword(s):  
Pericardial Effusion ◽  
Aortic Dissection ◽  
Case Series ◽  
District General Hospital ◽  
X Rays ◽  
Case Review ◽  
Retrospective Case ◽  
Superior Mediastinum ◽  
Presenting Symptoms ◽  
Life Threatening

Objective Aortic dissection is not a rare life-threatening emergency. Undiagnosed and untreated aortic dissection is associated with a high mortality. A review of cases in the hospital may provide a baseline picture to guide clinical decisions. Design Retrospective case review for a period of 3 years and 4 months. Setting District general hospital near the Hong Kong – Shenzhen ‘border’ with 24-hour Accident & Emergency service but without cardiothoracic surgical capability. Population All cases coded as ‘aortic dissection’ in the computerized ‘Clinical Management System’ of the hospital. Main outcome measures Date, sex, age, history of hypertension, presenting symptoms, pulse deficit, chest X-ray findings, pericardial effusion, A&E diagnosis, type of dissection and patient outcome. Results From August 1998 to November 2001, 26 cases of aortic dissection were identified. There were 19 males and 7 females. Age range was 26 to 90 years (mean 65.04 ± SD 15.04, median 66.50, mode 65). In the plain chest X-rays, widened superior mediastinum (>8 cm) was present in 19 patients (73.1%) and pleural effusion in three (11.5%). Pericardial effusion was found in six patients (23.1%). As regard to outcome, 11 were discharged home (42.3%), 14 were transferred to cardiothoracic surgical unit (where two subsequently died) and one died in the hospital. Conclusion The prevalence of aortic dissection may be more common than is generally appreciated by emergency physicians. Owing to its variable clinical presentations mimicking other diseases, the diagnosis of aortic dissection is easily missed. Higher clinical vigilance should be exercised for this potentially deadly condition.

Establishing the Need for an Evidence-Based Treatment Algorithm for Peritonsillar Abscess in Children

2018 ◽  
Vol 57 (12) ◽  
pp. 1385-1390 ◽  
Author(s):  
Maria Carratola Grant ◽  
Blake Raggio ◽  
Blair Barton ◽  
J. Lindhe Guarisco
Keyword(s):  
Treatment Algorithm ◽  
Case Series ◽  
Cervical Lymphadenopathy ◽  
Oral Intake ◽  
Peritonsillar Abscess ◽  
Retrospective Case ◽  
Evidence Based Treatment ◽  
Presenting Symptoms ◽  
Evidenced Based ◽  
Symptoms And Signs

In this retrospective case series, we report clinical factors associated with pediatric peritonsillar abscess (PTA), with hopes of contributing to the design of an evidenced-based, economic treatment approach. Charts were examined for presenting symptoms and signs. Each of these were analyzed for association with the presence of PTA and for association with treatment. We found that, with the exception of leukocytosis, the signs/symptoms that prompted treatment correlate with those that indicate the presence of PTA. However, there are several signs/symptoms, namely, referred otalgia, cervical lymphadenopathy, and decreased oral intake, that were associated with PTA but unassociated with treatment. Treatment can be aided by establishing an algorithm that accounts for the symptoms/signs most correlated with true, drainable abscess.

scholarly journals Chondromyxoid Fibroma of the Pelvis: Institutional Case Series With a Focus on Distinctive Features

2018 ◽  
Vol 27 (4) ◽  
pp. 352-359 ◽  
Author(s):  
Takashi Sono ◽  
Alisha D. Ware ◽  
Edward F. McCarthy ◽  
Aaron W. James
Keyword(s):  
Case Series ◽  
Benign Neoplasm ◽  
Dystrophic Calcification ◽  
Chondromyxoid Fibroma ◽  
Case Review ◽  
Retrospective Case ◽  
Distinctive Features ◽  
Histopathologic Diagnosis ◽  
Mean Size ◽  
Age Range

Chondromyxoid fibroma (CMF) is a relatively uncommon benign bone tumor of cartilaginous differentiation. The primary pitfall in the histopathologic diagnosis of CMF is confusion with a high-grade chondrosarcoma, owing to the atypical stellate and spindled cells set within a chondromyxoid background. CMF is particularly challenging to diagnose within the pelvis, where clinical suspicion for chondrosarcoma is high and benign lesions may grow to a large size to occupy the pelvic bones. In our practice, we noted this difficulty in several consecutive cases, especially when older patients presented with CMF within the pelvis. This prompted an institutional retrospective case review of all CMF within the pelvis. In 10 cases, we found overall that CMF of pelvis occurred in an older age range (mean age = 48.6 years), was larger in size (mean size = 6.0 cm), and showed a higher rate of soft tissue extension (50%) as compared with prior reports of nonpelvic CMF. Typical histologic features of CMF were seen in all cases; however, a high frequency of dystrophic calcification (50%) and necrosis (30%) was observed. Of interest, these aggregate demographic, radiologic, and histologic findings are all consistent with a benign neoplasm that has grown undetected within the pelvis over a long period of time. Recognition of these differences between pelvic CMF and tumors involving other sites will aid in avoiding misdiagnosis of this uncommon entity.

Sign in / Sign up

Export Citation Format

Share Document