Comparison of Subpectoral versus Prepectoral Immediate Implant Reconstruction after Skin- and Nipple-Sparing Mastectomy in Breast Cancer Patients: A Retrospective Hospital-Based Cohort Study

Introduction: Implant-based immediate breast reconstruction (IBR) is a common surgical procedure in breast cancer patients. Comparative analysis concerning the placement of implants is still lacking. Hence, we aimed to analyze pre- versus subpectoral IBR in breast cancer patients. Patients: A single-center experience with implant-based IBR following skin/nipple-sparing mastectomy was evaluated. Patient demographics, incidence of major complications, and quality of life assessed with BREAST-Q were compared between the pre- and subpectoral cohort. Results: A total of 63 patients were included in this analysis of whom 29 underwent subpectoral and 34 underwent prepectoral IBR. Median duration of surgery was prolonged in the subpectoral versus the prepectoral group (104 ± 28 vs. 80 ± 91 min; p < 0.05). The mean number of major complications was significantly increased in the subpectoral group (1.41 ± 1.76 vs. 0.47 ± 0.75 per patient; p < 0.05). Detailed analysis showed a significantly increased incidence of implant dislocation (p < 0.05) and a trend concerning capsular contracture (p = 0.086, not significant) and necrosis (p = 0.092, not significant) in the subpectoral group. Quality of life was equal in both groups. Conclusion: The mean number of major complications in the subpectoral group should be considered when IBR is indicated. Prepectoral IBR seems to be a feasible alternative surgical treatment option with less major complications in selected patients.

Download Full-text

Health-related quality of life and its predictors among patients with breast cancer at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

Health and Quality of Life Outcomes ◽

10.1186/s12955-019-1239-1 ◽

2019 ◽

Vol 17 (1) ◽

Cited By ~ 3

Author(s):

Selamawit Gebrehiwot Sibhat ◽

Teferi Gedif Fenta ◽

Beate Sander ◽

Gebremedhin Beedemariam Gebretekle

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Patients ◽

Addis Ababa ◽

Breast Cancer Patients ◽

Specialized Hospital ◽

Tikur Anbessa Specialized Hospital ◽

The Mean ◽

Eortc Qlq

Abstract Background Breast cancer is the second most prevalent malignancy in Ethiopia and severely affects patients’ health-related quality of life (HRQOL). We aimed to assess HRQoL, factors influencing HRQoL, and utilities among breast cancer patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods A hospital-based cross-sectional study was conducted in Tikur Anbessa Specialized Hospital from December 2017 to February, 2018. A total of 404 breast cancer patients were interviewed using the validated Amharic version of the European Organization for Research and Treatment of Cancer module (EORTC QLQ-C30), EORTC QLQ-BR23, and Euro Quality of Life Group’s 5-Domain Questionnaires 5 Levels (EQ-5D-5 L) instruments. Mean scores and mean differences of EORTC- QLQ-C30 and EORTC- QLQ-BR23 were calculated. One-way ANOVA test was employed to determine the significance of mean differences among dependent and independent variables while stepwise multivariate logistic regression was used to identify factors associated with the global quality of life (GQOL). Coefficients and level specific utility values obtained from a hybrid regression model for the Ethiopian population were used to compute utility values of each health state. Data was analyzed using SPSS version 23. Results The mean age of patients was 43.94 ± 11.72 years. The mean score for GQoL and visual analog scale was 59.32 ± 22.94 and 69.94 ± 20.36, respectively while the mean utility score was 0.8 ± 0.25. Predictors of GQoL were stage of cancer (AOR = 7.94; 95% CI: 1.83–34.54), cognitive functioning (AOR = 2.38; 95% CI: 1.32–4.31), pain (AOR = 7.99; 95% CI: 4.62–13.83), financial difficulties (AOR = 2.60; 95% CI: 1.56–4.35), and future perspective (AOR = 2.08; 95% CI: 1.24–3.49). Conclusions The overall GQoL of breast cancer patients was moderate. Targeted approaches to improve patients’ HRQoL should consider stage of cancer, cognitive functioning, pain, financial status and worries about the patient’s future health. This study also provides estimates of EQ-5D utility scores that can be used in economic evaluations.

Download Full-text

Feasibility study of nipple-sparing mastectomy for Japanese breast cancer patients.

Journal of Clinical Oncology ◽

10.1200/jco.2012.30.27_suppl.166 ◽

2012 ◽

Vol 30 (27_suppl) ◽

pp. 166-166

Author(s):

Maiko Takahashi ◽

Hiromitsu Jinno ◽

Tetsu Hayashida ◽

Yuko Kitagawa

Keyword(s):

Breast Cancer ◽

Local Recurrence ◽

Cancer Patients ◽

Preoperative Imaging ◽

Control Group ◽

Breast Cancer Patients ◽

Significant Difference ◽

The Mean ◽

Nipple Sparing Mastectomy ◽

Nipple Sparing

166 Background: Nipple-sparing mastectomy (NSM) has been gathering increased recognition as an alternative to more traditional mastectomy approaches. However, the oncological safety of these procedures is still to be elucidated. The purpose of this study is to investigate technical feasibility of NSM without increasing the risk of local recurrence and complications. Methods: Ninety-eight stage 0-III breast cancer patients received NSM between January 2001 and April 2012 at Keio University Hospital. Eligible patients were without skin involvement and not indicated for breast-conserving therapy by preoperative imaging. The pathological analysis of the subareolar tissue was performed and nipple-areolar-complex (NAC) would be removed if positive. Four hundred seventy-four breast cancer patients who had mastectomy during the same period were used as a control group. Results: The median age was 46.0 years (range 29–68). The mean clinical tumor size was 2.8±1.2cm and the mean distance between the nipple and the tumor was 2.5±1.7cm. Ninety-one patients (92.9%) had clinically node-negative status. NAC involvement was observed in 3 patients (3.1%). Three patients (3.1%) presented with epidermal necrosis. After a median follow-up period of 37.3 months (range 1-136), there were 7 recurrences (7.1%), including 4 local recurrences (4.1%) and 3 distant metastases (3.1%). There was no statistically significant difference in local recurrence between the patients with NSM and mastectomy (4.1% vs. 3.2%; p=0.16). Immediate and delayed reconstruction was performed in 2 cases (2.0%) and 41 cases (41.8%), respectively. Conclusions: Our results suggested NSM may provide oncologic safety for strongly motivated and carefully selected patients.

Download Full-text

Female Breast Cancer Patients, Mastectomy-Related Quality of Life: Experience from Ethiopia

International Journal of Breast Cancer ◽

10.1155/2020/8460374 ◽

2020 ◽

Vol 2020 ◽

pp. 1-6

Author(s):

Engida Abebe ◽

Kassaw Demilie ◽

Befekadu Lemmu ◽

Kirubel Abebe

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Patients ◽

Female Breast Cancer ◽

Breast Cancer Patients ◽

Related Quality ◽

Eortc Qlq C30 ◽

The Mean ◽

Eortc Qlq

Background. Mastectomy is the most common form of treatment for a developing-nation woman diagnosed with breast cancer. This can have huge effect on a women’s quality of life. Objective. To assess mastectomy-related quality of life in female breast cancer patients. Materials and Methods. A facility-based cross-sectional descriptive study was conducted from February 1st to July 30th, 2018. A pretested structured data collection format was used to interview patients. The European Organization for Research and Treatment for Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and Breast Cancer-Specific (EORTC QLQ-BR23) were used to evaluate quality of life, functional capacity, and symptom scales. Data was analyzed with SPSS version 23. Results. The mean age of the 86 patients was 43.2 years (SD±11.4) and ranged from 25 to 70 years. 54.7% (47) of patient’s mastectomy was done on the right side. Based on EORTC QLQ-C30 global health status/QOL scale, the mean score was 48.3. On the evaluation of EORTC QLQ-BR23, future perspective about their health was low with a mean of 40.3 and their sexual functioning and enjoyment were significantly affected with mean scores of 85.3 and 71.2, respectively. Symptom scales were low with mean from 19.1 to 24.5. Majority (49, 57%) of respondents do not want to have breast reconstruction after mastectomy. Conclusion. Our breast cancer patients who underwent mastectomy performed poor in terms of quality of life as compared to international findings which demands attention in incorporating psychosocial aspects in the treatment plan.

Download Full-text

Đánh giá chất lượng cuộc sống bệnh nhân ung thư vú sau phẫu thuật

Journal of Clinical Medicine- Hue Central Hospital ◽

10.38103/jcmhch.2020.60.10 ◽

2020 ◽

Author(s):

Đức Thành Nguyễn

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Patients ◽

Social Factor ◽

Radical Mastectomy ◽

Age Group ◽

Breast Cancer Patients ◽

Cross Sectional ◽

The Mean

EVALUATION QUALITY OF LIFE BREAST CANCER PATIENTS POST – OPERATIVE Objective: This descriptive and cross-sectional study quality of life breast cancer postoperative (include both mastectomy and Breast conserving surgery) and dertermine social factors related to quality of life breast cancer postoperative. Method: We collected 60 patients of carcinoma breast cancer post modified radical mastectomy. They were interviewed directly through questionnaires on quality of life of EORTC QLQ C-30. Results: The results showed that the mean age at this study was 47,6 years. Younger women in age group 30-39 years had faird worst on physical, social, and emotional scores as compare to older women in the age group of 70-79 years. Conclusion: The mean socres quality of life of patients with breast cancer postoperative at Thai Nguyen Oncology Center was differencebetween younger patient (30-39) years and older paient (70-79) years. In addition, Age and education status on this study were factor which related to quality of life in Breast Cancer Patients. Keywords: Breast cancer, Quality of life, social factor

Download Full-text

The effect of psychological group intervention on emotional problems, event impact and quality of life in breast cancer patients under radiotherapy: a pilot study

Journal of Evidence-Based Psychotherapies ◽

10.24193/jebp.2017.2.8 ◽

2017 ◽

Vol 17 (2) ◽

pp. 133-146 ◽

Cited By ~ 2

Author(s):

Mihaela Iancu ◽

◽

Florina Pop ◽

Raluca Ioana Farcaș ◽

Amfiana Gherman ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Pilot Study ◽

Cancer Patients ◽

Group Intervention ◽

Emotional Problems ◽

Breast Cancer Patients

Download Full-text

PSYCHOLOGICAL REHABILITATION AND SCREENING OF EMOTIONAL STRESS IN CANCER PATIENTS

Problems in oncology ◽

10.37469/0507-3758-2017-63-2-316-319 ◽

2017 ◽

Vol 63 (2) ◽

pp. 316-319 ◽

Cited By ~ 2

Author(s):

Valentina Chulkova ◽

Tatyana Semiglazova ◽

Margarita Vagaytseva ◽

Andrey Karitskiy ◽

Yevgeniy Demin ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Patient ◽

Cancer Patients ◽

Emotional Stress ◽

Self Esteem ◽

Breast Cancer Patients ◽

Psychological Study ◽

Psychological Assistance

Psychological rehabilitation is an integral part of rehabilitation of a cancer patient. Psychological rehabilitation is aimed at a patient adaptation in the situation of the disease and improvement his quality of life. Understanding of an oncological disease is extreme and (or) crisis situation and monitoring dynamics of the psychological statement of a patient allows using differentiated approach in the provision of professional psychological assistance. The modified scale of self-esteem level of distress (IPOS) was used for screening of mental and emotional stress of cancer patients. There were selected groups of cancer patients who were most in need of professional psychological assistance. Results of a psychological study of one of these groups - breast cancer patients - are presented.

Download Full-text