scholarly journals Once Weekly Application of Urea 40% and Bifonazole 1% Leads to Earlier Nail Removal in Onychomycosis

2020 ◽  
Vol 6 (5) ◽  
pp. 304-308 ◽  
Author(s):  
Avner Shemer ◽  
Yossi Eshel ◽  
Aditya K. Gupta ◽  
Renata Farhi ◽  
Eckart Haneke ◽  
...  
2013 ◽  
Vol 2013 ◽  
pp. 1-5
Author(s):  
Amr A. Abdelgawad ◽  
Enes Kanlic

Nonunion of long bones fixed with nails may result in implant failure. Removal of a broken intramedullary nail may be a real challenge. Many methods have been described to allow for removal of the broken piece of the nail. In this paper, we are reviewing the different techniques to extract a broken nail, classifying them into different subsets, and describing a new technique that we used to remove a broken tibial nail with narrow canal. Eight different categories of implant removal methods were described, with different methods within each category. This classification is very comprehensive and was never described before. We described a new technique (hook captured in the medulla by flexible nail introduced from the locking hole) which is a valuable technique in cases of nail of a small diameter where other methods cannot be used because of the narrow canal of the nail. Our eight categories for broken nail removal methods simplify the concepts of nail removal and allow the surgeon to better plan for the removal procedure.


HortScience ◽  
2022 ◽  
Vol 57 (1) ◽  
pp. 32-39
Author(s):  
Dharti Thakulla ◽  
Bruce L. Dunn ◽  
Carla Goad ◽  
Bizhen Hu

Algae is not desirable in hydroponics and creates problems such as reduced yield and decreased dissolved oxygen, and affects the physiology of plants and, thus, needs to be controlled. An experiment was conducted in Ebb and Flow hydroponic systems to investigate the application timing and rates of two hydrogen peroxide products (Zerotol and PERpose Plus). Treatments included 35 mL weekly, 35 mL biweekly, 70 mL weekly, 70 mL biweekly, and a control with no application of hydrogen peroxide using a 40-gallon reservoir of water. Pepper ‘Early Jalapeno’ and ‘Lunchbox Red’ and tomato ‘Geronimo’ and ‘Little Sicily’ were used. The study was conducted in a split-plot design with two replications over time. Plant growth parameters, including plant height, flower number, net CO2 assimilation, fresh weight, and dry weight were recorded. Algae data, including dry weight, algae cell counts, and chl a were also measured. Results indicated that with increasing rate and timing of either product decreased algae counts, dry weight, and chl a values. However, weekly and biweekly application of 70 mL of both products were not different for algae quantification. In pepper, plant height, shoot fresh and dry weight, and root fresh and dry weight were found to be significantly greater with Zerotol 35 mL biweekly, Zerotol 70 mL weekly, PERpose Plus 35 mL biweekly, and PERpose Plus 70 mL weekly compared with the control. ‘Lunchbox Red’ was significantly greater than ‘Early Jalapeno’ in all growth parameters, except soil plant analysis development (SPAD). ‘Lunchbox Red’ had the greatest flower number, with weekly application of 70 mL PERpose Plus. In tomato, greatest flower number and SPAD were observed in ‘Geronimo’ with a weekly application of 70 mL PERpose Plus and 70 mL Zerotol, respectively. Greater shoot and root fresh and dry weight for both tomato cultivars were recorded with 35 mL biweekly or 70 mL weekly application with either product. The results from both plants as well as algae analysis suggest that weekly application of 70 mL of either Zerotol or PERpose Plus produced the best results in terms of controlling algae and improving the growth of pepper and tomato plants.


Author(s):  
Christopher A. Iobst ◽  
Markus Winther Frost ◽  
Jan Duedal Rölfing ◽  
Ole Rahbek ◽  
Anirejuoritse Bafor ◽  
...  

Aims Limb lengthening nails have largely replaced external fixation in limb lengthening and reconstructive surgery. However, the adverse events and high prevalence of radiological changes recently noted with the STRYDE lengthening nail have raised concerns about the use of internal lengthening nails. The aim of this study was to compare the prevalence of radiological bone abnormalities between STRYDE, PRECICE, and FITBONE nails prior to nail removal. Methods This was a retrospective case series from three centres. Patients were included if they had either of the three limb lengthening nails (STYDE, PRECICE, or FITBONE) removed. Standard orthogonal radiographs immediately prior to nail removal were examined for bone abnormalities at the junction of the telescoping nail parts. Results In total, 306 patients (168 male, 138 female) had 366 limb lengthening nails removed. The mean time from nail insertion to radiological evaluation was 434 days (36 to 3,015). Overall, 77% of STRYDE nails (20/26) had bone abnormalities at the interface compared with only 2% of FITBONE (4/242) and 1% of PRECICE nails (1/98; p < 0.001). Focal osteolysis in conjunction with periosteal reaction at the telescoping interface was only observed in STRYDE nails. Conclusion Bone abnormalities at the interface of telescoping nail parts were seen in the majority of STRYDE nails, but only very rarely with FITBONE or PRECICE nails. We conclude that the low prevalence of radiological changes at the junctional interface of 242 FITBONE and 98 PRECICE nails at the time of nail removal does not warrant clinical concerns.


2010 ◽  
pp. 854-856
Author(s):  
Andrew Moore ◽  
Robert E. Meehan
Keyword(s):  

2019 ◽  
Vol 56 (5) ◽  
pp. 1331-1337
Author(s):  
Fabián Correa-Morales ◽  
Felipe Dzul-Manzanilla ◽  
Wilbert Bibiano-Marín ◽  
José Vadillo-Sánchez ◽  
Anuar Medina-Barreiro ◽  
...  

Abstract A cluster-randomized controlled trial quantified the entomological efficacy of aerial ultra-low volume (AULV) applications of the insecticide chlorpyrifos against Aedes aegypti in Puerto Vallarta, México, during November–October 2017. The trial involved 16 large (1 × 1 km) clusters distributed between treatment-control arms. Primary endpoint was the abundance of Ae. aegypti indoors (total adults, females, and blood-fed females) collected using Prokopack aspirators. After four consecutive weekly cycles of AULV, all adult Ae. aegypti infestation indices were significantly lower in the treatment arm (OR and IRR ≤ 0.28). Efficacy in reducing indoor Ae. aegypti increased with each weekly application cycle from 30 to 73% (total adults), 33 to 76% (females), and 45.5 to 89% (blood-fed females). Entomological indices remained significantly lower in the treatment arm up to 2 wk after the fourth spraying round. Performing AULV spraying can have significant and lasting entomological impact on Ae. aegypti as long as multiple (ideally four) spray cycles are implemented using an effective insecticide.


2009 ◽  
Vol 27 (15_suppl) ◽  
pp. 1101-1101
Author(s):  
H. Stemmler ◽  
N. Harbeck ◽  
I. Groell der Rivera ◽  
U. Vehling-Kaiser ◽  
G. Rauthe ◽  
...  

1101 Background: We investigated the toxicity and efficacy of weekly applied docetaxel compared to its standard 3-weekly application in pts previously untreated with chemotherapy for MBC. Methods: In the D2 trial (>60 yrs or KPS 60–80%), pts were randomized to receive docetaxel either on a 3-weekly (75 mg/m2 q3w) or on a weekly schedule (30 mg/m2 d1, 8, 15 q4w). In the D4 study (<65 yrs or KPS 70–100%), pts received doxorubicin (50 mg/m2, d 1) in addition to docetaxel given either at q3w dose of 75 mg/m2 or at as 35 mg/m2 (days 1, 8, 15, q4w). Results: The primary endpoint (toxicity) was achieved in D2 and failed in D4. Both studies were terminated prematurely (D2 n = 102/162 D4 n = 85/242 pts). In the D2 study, leucopenia ≥grade 3 was significantly less frequent in the weekly arm (4.2% q1w versus 51.9% q3w, p < 0.0001). In the weekly versus 3-weekly arm ORR was 26.8% versus 46.9% (p = 0.08), TTP was 5.4 versus 6.3 months (p = 0.91), and OS was 22.7 versus 15.8 months (p = 0.24). In the D4 study, an unexpectedly low rate of leucopenia ≥grade 3 was observed in the 3-weekly arm (29.7% q3w versus 35.7% q1w, p = 0.21). In the weekly versus 3-weekly arm, ORR was 50.0% versus 55.0% (p = 0.82), TTP was 6.2 versus 10.3 months (p = 0.36), and OS was 20.5 versus 28.9 months (p = 0.98). Non-hematological toxicity ≥grade 3 was generally mild and comparable within the two schedules. Conclusions: The present data support the feasibility of both, the weekly and the 3-weekly regimen of docetaxel application either as a single-agent or in combination with doxorubicin. As expected, leucopenia seems avoidable in the weekly scheduled of single-agent docetaxel (D2), whereas a combined weekly schedule of docetaxel/doxorubicin as given in the D4 study failed to confirm an expected lower rate of leucopenia. [Table: see text]


2008 ◽  
Vol 42 (4) ◽  
pp. 312-318 ◽  
Author(s):  
M.J. Altenburger ◽  
J.F. Schirrmeister ◽  
K.-T. Wrbas ◽  
M. Klasser ◽  
E. Hellwig

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