Risk factors and prognosis of pediatric open globe injuries without initial light perception

Purpose: To investigate the possible risk factors and prognosis of initial no light perception (NLP) in pediatric open globe injuries (POGI). Procedures: This retrospective, comparative, interventional case-control study included 865 eyes of POGI patients presenting to a tertiary referral ophthalmic center from 1 January 2011 to 31 December 2015. Eyes were divided into two groups: NLP group included eyes with initial NLP, and light perception(LP) group included eyes with initial LP or vision better than LP. Results: The following risk factors were significantly related to initial NLP: severe intraocular hemorrhage (OR=3.287, p=0.015), retinal detachment (RD) (OR=2.527, p=0.007), choroidal damage (OR=2.680, p=0.016) and endophthalmitis (OR=4.221, p＜0.001). Choroidal damage is related to remaining NLP after vitreoretinal surgery (OR=12.384, p=0.003). At the last visit, more eyes in the NLP group suffered from silicone oil–sustained status (OR=0.266, p=0.020) or ocular atrophy (OR=0.640, p=0.004), and less eyes benefitted from final LP (OR=41.061, p＜0.001) and anatomic success (OR=4.515, p＜0.001). Conclusion: Severe intraocular hemorrhage, RD, choroidal damage and endophthalmitis occurred more often in POGI with initial NLP. Choroidal damage was the major factor related to an NLP prognosis. Traumatized eyes with initial NLP could be anatomically and functionally preserved by vitreoretinal surgery.

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CASE–CONTROL STUDY OF RISK FACTORS FOR NO LIGHT PERCEPTION AFTER OPEN-GLOBE INJURY

Retina ◽

10.1097/iae.0b013e318213d8c7 ◽

2011 ◽

Vol 31 (10) ◽

pp. 1988-1996 ◽

Cited By ~ 15

Author(s):

Kang Feng ◽

Lijun Shen ◽

Xiuqin Pang ◽

Yanrong Jiang ◽

Hongping Nie ◽

...

Keyword(s):

Risk Factors ◽

Case Control Study ◽

Case Control ◽

Light Perception ◽

Open Globe Injury ◽

Open Globe ◽

Control Study

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Risk Factors for Band Keratopathy in Aphakic Eyes With Silicone Oil Tamponade for Open-Globe Injuries: A Multicenter Case-Control Study

Frontiers in Medicine ◽

10.3389/fmed.2021.713599 ◽

2021 ◽

Vol 8 ◽

Author(s):

Kai He ◽

Mengyu Liao ◽

Yun Zhu ◽

Bohao Cui ◽

Haoyu Chen ◽

...

Keyword(s):

Risk Factors ◽

Case Control Study ◽

Silicone Oil ◽

Significant Risk ◽

Case Control ◽

Open Globe ◽

Band Keratopathy ◽

Aphakic Eyes ◽

Silicone Oil Tamponade ◽

Control Study

Band keratopathy (BK) is a common complication in aphakic eyes with silicone oil tamponade for open-globe injury (OGI), characterized by the grayish-white opacities in the cornea, resulting in a significantly decreased vision when extending to the visual axis. To identify the risk factors for BK in aphakic eyes following vitreoretinal surgical treatment with silicone oil tamponade for OGIs, we performed a multicenter case-control study. The incidence of BK was 28% (28/100 eyes). The multivariate binary logistic regression revealed the silicone oil retention time (SORT) ≥6 months and zone III injury were significant risk factors for BK. From the hierarchical interaction, SORT ≥6 months had a significant risk for BK in eyes with rupture, aniridia, and zone III injury, while zone III injury had a significant risk for BK in eyes with rupture, incomplete/complete iris, and SORT ≥6 months. By using restricted cubic splines with three knots at the 25th, 50th, and 75th centiles to model the association of SORT with BK, we also found a marked increase in the risk for BK at ≥10 months and a slow increase after 6 months, but almost stable within 4–6 months.

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Clinical Analysis of Adult Severe Open-Globe Injuries in Central China

Frontiers in Medicine ◽

10.3389/fmed.2021.755158 ◽

2021 ◽

Vol 8 ◽

Author(s):

Hongling Chen ◽

Junjun Han ◽

Xianliang Zhang ◽

Xuemin Jin

Keyword(s):

Vision Loss ◽

Silicone Oil ◽

Public Health Problem ◽

Central China ◽

Anatomical Reconstruction ◽

Light Perception ◽

Male Predominance ◽

Open Globe ◽

Department Of Ophthalmology ◽

Open Globe Injuries

Purpose: To describe the characteristics, management, and outcomes of adult severe open-globe injured (OGI) eyes.Methods: Retrospective chart review of inpatients with initial visual acuity (VA) of light perception (LP) or no light perception (NLP) associated with OGI between 2017 and 2020 at Department of Ophthalmology, Henan Eye Institute, Henan Eye Hospital, Henan provincial People's Hospital.Results: Six hundred twenty-five eyes of 622 adult patients with initial VA of LP or NLP associated with open-globe injuries (OGIs) were included. The mean age was 47.8 ± 14.1 years with the range from 18 to 91 years. Significant male predominance was noted (81.5%). The most common type of these severe OGIs was rupture (65.8%). Traffic accidents accounted for 13.5% followed by fall/tumble (10.9%) and nail/wire (10.9%) of all the severe OGIs. Almost half of the injuries happened at workplace (47.2%). Initially, 78.7% eyes just received primary debridement and wound closure, while 8.5% eyes with no possible of anatomical reconstruction received evisceration. After initial management, 350 eyes received subsequent operation, including 239 eyes underwent vitrectomy + silicone oil/(+cataract remove). Finally, over 6 months follow-up, 137 eyes (21.9%) were eviscerated, 150 eyes (24.0%) got atrophied, while 132 eyes (21.1%) retain some VA. Fifty-three eyes (8.5%) got VA of 0.3–1.5.Conclusion: Severe OGIs are most seen in the young, middle-aged, and male working population and remain a serious public health problem, resulting in significant vision loss or Evisceration of eyes. Effective preventive measures should be taken for the individuals in these groups.

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