scholarly journals Prevalence and associated risk factors of transfusion transmissible infections among blood donors at Regional Blood Transfusion Center Nakuru and Tenwek Mission Hospital, Kenya

2019 ◽  
Vol 34 ◽  
Author(s):  
Grace Bartonjo ◽  
Joseph Oundo ◽  
Zipporah Ng’ang’a
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Blood Donors ◽  
Mission Hospital ◽  
Transfusion Center ◽  
Blood Transfusion Center ◽  
Associated Risk Factors

scholarly journals Transfusion-Transmitted Infections and associated risk factors at the Northern Zone Blood Transfusion Center in Tanzania: A study of blood donors between 2017 and 2019

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0249061
Author(s):  
Alex Mremi ◽  
James J. Yahaya ◽  
Mramba Nyindo ◽  
Edson Mollel
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Cross Sectional Study ◽  
Sub Saharan Africa ◽  
P Value ◽  
Cross Sectional ◽  
Transfusion Center ◽  
Blood Transfusion Center ◽  
Northern Zone ◽  
Associated Risk Factors

Background Blood transfusion saves many people every year that would otherwise have died. The present study aimed to provide an update and insightful information regarding prevalence of the common Transfusion-Transmitted Infections (TTIs) and associated factors among blood donors in Tanzania. Methods This was a cross-sectional study involving retrospectively collected data of blood donors from the Tanzania Northern Zone Blood Transfusion Center between 2017 and 2019. Descriptive statistics were performed to describe characteristics of the blood donors. Univariable and multivariable logistic regression analyses were performed to determine association between prevalence of TTIs and socio-demographic factors. P-value <0.05 was considered statistically significant. Results A total of 101, 616 blood donors were included in the present study of which 85,053(83.7%) were males while 16,563 (16.3%) were females. Of all participants, the majority 45,400 (44.7%) were aged between 18 and 25 years; 79,582 (78.3%) were voluntary non-remunerated donors while 22,034 (21.7%) were replacement donors. The vast majority of them 99,626 (98%) were first time blood donors while 1990 (2%) were multiple donors. The overall prevalence of TTIs was 10.1% (10,226 out of 101,616) of which the leading was HBV accounting for 5.1% (5,264 out of 101,616). Being a replacement donor was associated with all the four types of TTIs: HIV (AOR = 1.22, 95% CI = 1.10–1.35), HBV (AOR = 1.35, 95% CI = 1.27–1.44), HCV (AOR = 1.28, 95% CI = 1.12–1.46), and syphilis (AOR = 1.33, 95% CI = 1.20–1.48). Conclusions Our study has demonstrated that Tanzania has relatively high prevalence of TTIs compared to some countries in Sub-Saharan Africa. HBV infection seems to be the most common infection among blood donors and replacement blood donors are at a higher risk of harboring the commonest TTIs among blood donors.

scholarly journals Seroprevalence and Risk Factors Associated with Human Immunodeficiency Virus Infection Type 1 in Donors of the National Blood Transfusion Center of Libreville (Gabon)

2021 ◽  
pp. 16-24
Author(s):  
Christian Mangala ◽  
Therese Nkoa ◽  
Denis Maulot-Bangola ◽  
Franck Vivien Vigan Codjo ◽  
Joseph Fokam
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Dental Care ◽  
Blood Donors ◽  
Sexual Partners ◽  
Multiple Sexual Partners ◽  
Factors Associated ◽  
Transfusion Center ◽  
Blood Transfusion Center ◽  
Hiv 1

Background: Transmission of HIV through blood transfusion remains a public health problem, particularly in countries in Sub-Saharan Africa. However, no study has determined the epidemiological data regarding HIV-1 infection in Gabonese blood donors. The objective of this study is to assess the seroprevalence of HIV-1 and the risk factors associated with infection in donors from the National Blood Transfusion Center in Libreville (Gabon). Methods: A cross-sectional study carried out from June to August 2020 in 3669 persons donating blood at the National Blood Transfusion Center (NBTC). The ELISA technique (Evolis®, BioRad), the chemiluminescence technique (Cobas® e601, Roche), and the SD Bioline® HIV 1/2 test (Standard Diagnostics. Inc) were used for the detection of anti-HIV-1/2 antibodies and P24 antigen in donor plasma. Data were analyzed using SPSS software version 21.0, with p˂.05 considered statistically significant.  Results: The seropositivity rate HIV-1 was 0.8% (30/3669) (95% CI: 0.5; 1.1). The study was composed of 79.4% men and 20.6% women. The most representative age group was of 25-34 years with 54.5%. The seropositivity of men, women, and unrelated voluntary donors was 0.7%, 1.2%, and 1.0%, respectively. The risk factors such as the first blood donation (Adjusted Odds Ratio (AOR) = 0.1 [0.0 ;0.4], P= .002), multiple sexual partners (AOR = 6.2 [2.2;17.2], P= .001), primary educational level (AOR = 10.1 [1.4;75], P = .024), and dental care (AOR = 3.6 [1.2;11], P = .024) were significantly associated with HIV infection. About 0.14% of the patients had co-infection. Conclusion: In the Gabonese context, about one out of a hundred blood donors are HIV-infected. These carriers of HIV infection in the blood banks are mainly new donors with multiple sexual partners, limited education, and poor dental care.

The seroprevalence of parvovirus B19 antibody in blood donors at the National Blood Transfusion Center in Kinshasa

2019 ◽  
Vol 92 (3) ◽  
pp. 288-294 ◽  
Author(s):  
Alain Chabo Byaene ◽  
Zakayi Pius Kabututu ◽  
Dina Moustafa Abou Rayia ◽  
Mohamed Mohamed Adel El‐Sokkary
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Parvovirus B19 ◽  
Transfusion Center ◽  
Blood Transfusion Center

scholarly journals Prevalence of Hepatitis B, C and HIV infection in blood donors of Multan region

2016 ◽  
Vol 10 (4) ◽  
Author(s):  
Muhammad Arif Mahmood ◽  
Shireen Khawar ◽  
Abdul Hameed Anjum ◽  
Siraj Munir Ahmed ◽  
Shahid Rafiq ◽  
...  
Keyword(s):  
General Population ◽  
Blood Transfusion ◽  
Hepatitis B ◽  
Hiv Infection ◽  
Blood Donors ◽  
Population Data ◽  
Study Groups ◽  
Similar Data ◽  
Transfusion Center ◽  
Blood Transfusion Center

Acute and chronic viral hepatitis are common public health problems in Pakistan, and associated with serious complications. The carrier rate of HBsAg is quoted to be around 10% in general population while the prevalence of HCV in blood donors is 4.8 %. Data regarding the prevalence of hepatitis B and C virus infections among healthy blood donors is well established in Karachi, Rawalpindi, Islamabad, Faisalabad, Lahore and Abbotabad areas, but similar data is not available for Multan population. Data regarding the epidemiology of HIV infection among blood donors is not available at most of the blood transfusion centers. In this study six thousands (6000) consecutive young healthy voluntary blood donors (age 16-50 years) comprising of 5476 males and 524 females, belonging to Multan region were included from "Blood Transfusion Center Nishtar Hospital Multan" & "Fatmid Blood Transfusion Center Multan" and were tested for HbsAg, Anti-HCV and HIV. Prevalence of Hepatitis B, C and HIV Infection was 3.37%, 0.27% and 0% respectively. The reported prevalence figures for HBsAg & Anti-HCV in other studies are quite variable, depending upon screening protocol, study groups selected and methodology of testing. If data from all the blood transfusion centers of Pakistan is collected and published, we can get representative prevalence values of HBV, HCV and HIV infection of the general population.

scholarly journals HBc antibody seroprevalence in HBs negative antigen blood donors at the Chad National Blood Transfusion Center in NDjamena

2021 ◽  
Vol 20 (1) ◽  
pp. 1-8
Author(s):  
Mbanga Djimadoum ◽  
Bessimbaye Nadlaou ◽  
Habkréo Mayanna ◽  
Doumdé Georges ◽  
Barro Nicolas
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Transfusion Center ◽  
Blood Transfusion Center

scholarly journals ABO & RHESUS BLOOD GROUPS

2005 ◽  
Vol 12 (04) ◽  
pp. 368-371
Author(s):  
ABDUL REHMAN ◽  
Muhammad Akram Saeed ◽  
MUHAMMAD AYUB KHAN ◽  
Ahmad Rafique ◽  
MUHAMMAD ASHRAF ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Blood Group ◽  
Blood Donors ◽  
Cross Sectional Study ◽  
Abo Blood Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Transfusion Center ◽  
Blood Transfusion Center ◽  
Study Setting

`Objective: To know the prevalence of ABO and Rhesus blood groups.Design: Observational cross sectional study. Setting: Blood transfusion Center Tehsil Headquarter HospitalLiaquatpur. Subjects and Methods: The data of blood donors from 2001 to 2003. Results: Total numbers of donorsstudied were 1389. The commonest ABO blood group was O present in 44.56% (CL 41.97% - 47.20%) followed byB in 32.54% (CL 30.13% - 35.06%), A in 20.88% (CL 18.82% - 23.10%) and AB in 2.02% (CL 1.39% - 2.91%) donorswhile 90.35% (CL 88.68% - 91.80%) donors were Rh +ve and 9.65% (CL 8.20% - 11.32%) were Rh -ve. Thecommonest ABO +ve group was O +ve present in 40.03% (CL 37.48% - 42.69%) followed by B +ve in 30.31% (CL27.95% - 32.78%), A +ve in 18.21% (CL 16.27% - 20.34%) and AB +ve in 1.8% (CL 1.21% - 2.66%) donors. The mostcommon ABO -ve was O -ve present in 4.54% (CL 3.56% - 5.77%), A -ve in 2.66% (CL 1.93% - 3.66%), B -ve in 2.23%(CL 1.57% - 3.17%) donors. Conclusion: Blood group O is the commonest ABO blood group and 90.35% are RH +vein this area.

scholarly journals The contemporary status of the blood donorship in the Mari El Republic

2013 ◽  
Vol 94 (1) ◽  
pp. 116-120
Author(s):  
E Y Zangerova
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Components ◽  
Gender Distribution ◽  
Transfusion Center ◽  
Blood Transfusion Center ◽  
Weak Points ◽  
Contemporary Status ◽  
The Republic ◽  
First Time

Aim. To detect the weak points of the existing system of blood donors’ draw in, to define the paths of blood donorship development in the Republic of Mari El. Methods. The analysis of the existing system of donorship at the period from 2002 to 2011 was conducted according to the data of combined yearly reports, data of united blood transfusion center of the Republic of Mari El database, data of Russia’s blood transfusion system facilities activity analysis. The changes in the number of blood donors, activity of blood donors, and detection of blood-transmitted diseases markers were evaluated. Results. No need for further significant increase in the number of active donors was detected, since the modern methods of blood and blood components preparation allows to increase the amounts of required blood components by other ways. The decrease in donors’ mean age was registered, the share of donors younger than 30 increased 2.8-fold compared to 2002 and 1.46-fold compared to 2007. The mean age of donors is 33,94±0,14 years, gender distribution (females - 39.2%, males - 60.8%) do not collide with the gender distribution of the general population. The share of plasma donors has significantly increased (4.8-fold in 2011). Since 2009 the share of first-time donors has increased to 42.9%, indicating the instability of the group of people ready to donate blood. Electronic database introduction and active use allows to exclude people with blood-transmitted diseases and other absolute contraindications from donating blood. The share of people willing to donate blood with registered blood-transmitted diseases has relatively dropped from 4.18% in 2007 to 1.42% in 2011. Conclusion. The main goal of blood transfusion services of Mari El Republic is still to increase the number of permanent donors, donating blood regularly, it will allow to increase the safety of blood components produced and provide the blood transfusion services stability.

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