scholarly journals Fibrinogen and factor VII in the prediction of coronary risk. Results from the PROCAM study in healthy men.

1994 ◽  
Vol 14 (1) ◽  
pp. 54-59 ◽  
Author(s):  
J Heinrich ◽  
L Balleisen ◽  
H Schulte ◽  
G Assmann ◽  
J van de Loo
1993 ◽  
Vol 38 (6) ◽  
pp. 173-177 ◽  
Author(s):  
S.R. McEwan ◽  
H.T.O. Davies ◽  
E. Allan ◽  
D. Maclean ◽  
C.D. Forbes

Coronary heart disease has been described as Scotland's national disease and ways of reducing its incidence are therefore of paramount importance especially in younger males. A recent British Medical Journal paper1 has indicated that general practitioners can make little impact on patients' lifestyles. This paper shows that a cohort of Scottish men (Social Class III-V) responded well (80%) to offers of screening for risk factors of CHD, continued to attend for review and showed highly significant changes in their risk factor profiles. A committed enthusiastic primary care team have shown the potential for reducing coronary risk factors in so-called healthy men.


1991 ◽  
Vol 65 (04) ◽  
pp. 339-343 ◽  
Author(s):  
G D O Lowe ◽  
D A Wood ◽  
J T Douglas ◽  
R A Riemersma ◽  
C C A Macintyre ◽  
...  

SummaryPlasma viscosity, molecular markers of activated coagulation and fibrinolysis (fibrinopeptides A and Bβ15-42), coagulation factors (fibrinogen and factor VII) and antiplasmins were measured in 529 men aged 35-54 years and related to new angina pectoris (n = 117) and to coronary risk factors in controls without angina (n = 412). Five major risk factors (cigarette-smoking, blood pressure, cholesterol, triglyceride and body mass index) were each associated with increases in plasma viscosity, coagulation factors, and imbalance of coagulation over fibrinolysis (increased ratio of fibrinopeptide A/fibrinopeptide Bβ15-42). Increased viscosity and fibrinogen in smokers were partly reversed in exsmokers, but the imbalance of coagulation and fibrinolysis persisted. Cholesterol and triglyceride were also associated with increased antiplasmin activity. In men with angina, only fibrinogen was elevated compared to controls. We suggest that increased plasma viscosity and an imbalance of coagulation over fibrinolysis may be mechanisms by which known risk factors promote arterial thrombosis, but are not present in stable angina.


1989 ◽  
Vol 78 (1) ◽  
pp. 19-24 ◽  
Author(s):  
G.J. Miller ◽  
J.K. Cruickshank ◽  
L.J. Ellis ◽  
R.L. Thompson ◽  
H.C. Wilkes ◽  
...  

1997 ◽  
Vol 17 (8) ◽  
pp. 1539-1544 ◽  
Author(s):  
Ralf Junker ◽  
Jürgen Heinrich ◽  
Helmut Schulte ◽  
Jürgen van de Loo ◽  
Gerd Assmann

1995 ◽  
Vol 115 ◽  
pp. S105
Author(s):  
M. Cigolini ◽  
G. Targher ◽  
J.C. Scidell ◽  
M. Tonoli ◽  
F. Filippi ◽  
...  

1996 ◽  
Vol 26 (3) ◽  
pp. 247-253 ◽  
Author(s):  
M. CIGOLINI ◽  
G. TARGHER ◽  
J. C. SEIDELL ◽  
R. SCHIAVON ◽  
M. TONOLI ◽  
...  

2002 ◽  
Vol 56 (11) ◽  
pp. 1102-1107 ◽  
Author(s):  
JMW Wallace ◽  
MPA Hannon-Fletcher ◽  
PJ Robson ◽  
WS Gilmore ◽  
SA Hubbard ◽  
...  

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