Abstract 2476: Regular Physical Activity Prevents the Development of Left Ventricular Hypertrophy in Young Stage 1 Hypertensive Subjects: Results of the Harvest Study

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Lucio Mos ◽  
Pier Alberto Visentin ◽  
Paolo Mormino ◽  
Francesca Dorigatti ◽  
Olga Vriz ◽  
...  
Keyword(s):  
Physical Activity ◽  
Ventricular Hypertrophy ◽  
Leisure Time ◽  
Left Ventricular ◽  
Regular Physical Activity ◽  
Competitive Sports ◽  
Physically Active ◽  
Young Stage ◽  
Stage 1

A beneficial effect of physical activity on left ventricular mass( LVM) in the short term has been described in hypertension. Aim of this study was to investigate the long-term effect of regular physical activity on development of left ventricular hypertrophy (LVH) in a cohort of young hypertensive subjects. We studied 454 participants (317 men, mean age 33±8 years) without LVH at baseline whose physical activity status was consistent throughout the follow-up. BP was 146±11/94±5 mm Hg at baseline and 141±/90±8 mmHg after 3 months of non-pharmacological measures. Subjects were divided into 3 categories of physical activity (sedentary, n=281;leisure-time activities, n=140; competitive sports, n=33). Patients were seen every six months until they developed hypertension. Echocardiographic LVM was measured at entry, every 5 years, and/or at the time of hypertension development. Active subjects were younger (31±8 versus 34±8 years, p=.000) and leaner (24.4±3.0 vs 25.2±3.7 Kg/m2, p=.006) than sedentary ones, and were more frequently male (45% versus 22%, p=.000). During a median follow-up of 8.2 years, 32 subjects(7.3%) developed LVH (sedentary=10.3%, leisure-time activities=2.1%, competitive sports= 0%, p=.002). In a logistic regression, physically active groups combined (n=173) were less likely to develop LVH than the sedentary group with a crude OR=0.16 (CI, 0.05– 0.55). After controlling for sex, age, family history for hypertension, body weight, smoking, alcohol and coffee use, blood pressure, LVM, and follow-up time, the OR was 0.22 (CI, 0.06 – 0.77). BP declined over time in physically active subjects (−5.1±17.0/−0.5±10.2 mmHg) and slightly increased in sedentary ones (0.0±15.3/0.9±9.7 mmHg, adjusted p versus active=0.04/0.06). Inclusion of changes in BP over time into the logistic model slightly decreased the strength of the association between physical activity status and LVH development (OR=0.24,CI, 0.07– 0.85). Regular physical activity prevents the development of LVH in young stage 1 hypertensive subjects. Leisure-time and competitive sports activities seem to have both a beneficial effect on LVM. This effect is only partially dependent on the reduction in BP caused by exercise.

scholarly journals Impact of Regular Physical Activity on Aortic Diameter Progression in Paediatric Patients with Bicuspid Aortic Valve

2021 ◽  
Author(s):  
Emanuele Monda ◽  
◽  
Adelaide Fusco ◽  
Alessandro Della Corte ◽  
Martina Caiazza ◽  
...  
Keyword(s):  
Physical Activity ◽  
Ascending Aorta ◽  
Regular Physical Activity ◽  
Aortic Diameter ◽  
Sinus Of Valsalva ◽  
Physically Active ◽  
The Impact ◽  
Aorta Diameter ◽  
Sedentary Subjects

AbstractPatients with bicuspid aortic valve (BAV) have an increased risk of aortic dilation and aortic dissection or rupture. The impact of physical training on the natural course of aortopathy in BAV patients remains unclear. The aim of this study was to evaluate the impact of regular physical activity on aortic diameters in a consecutive cohort of paediatric patients with BAV. Consecutive paediatric BAV patients were evaluated and categorized into two groups: physically active and sedentary subjects. Only the subjects with a complete 2-year follow-up were included in the study. To evaluate the potential impact of physical activity on aortic size, aortic diameters were measured at the sinus of Valsalva and mid-ascending aorta using echocardiography. We defined aortic diameter progression the increase of aortic diameter ≥ 10% from baseline. Among 90 BAV patients (11.5 ± 3.4 years of age, 77% males), 53 (59%) were physically active subjects. Compared to sedentary, physically active subjects were not significantly more likely to have > 10% increase in sinus of Valsalva (13% vs. 8%, p-value = 0.45) or mid-ascending aorta diameter (9% vs. 13%, p-value = 0.55) at 2 years follow-up, both in subjects with sinus of Valsalva diameter progression (3.7 ± 1.0 mm vs. 3.5 ± 0.8 mm, p-value = 0.67) and in those with ascending aorta diameter progression (3.0 ± 0.8 mm vs. 3.2 ± 1.3 mm, p-value = 0.83). In our paediatric cohort of BAV patients, the prevalence and the degree of aortic diameter progression was not significantly different between physically active and sedentary subjects, suggesting that aortic dilation is unrelated to regular physical activity over a 2-year period.

Effects of 32-Year Leisure Time Physical Activity Discordance in Twin Pairs on Health (TWINACTIVE Study): Aims, Design and Results for Physical Fitness

2009 ◽  
Vol 12 (1) ◽  
pp. 108-117 ◽  
Author(s):  
Tuija Leskinen ◽  
Katja Waller ◽  
Sara Mutikainen ◽  
Sari Aaltonen ◽  
Paula H. A. Ronkainen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Physically Active ◽  
Childhood Experiences ◽  
Bone Properties ◽  
Fitness Tests ◽  
Health Related ◽  
And Function

AbstractThe physically active lifestyle is associated with low future morbidity and mortality, but the causality between physical activity and health is not always clear. As some inherited biological characteristics and childhood experiences may cause selection bias in observational studies, we sought to take them into account by identifying 16 twin pairs (7 MZ, 9 DZ, mean age 60 years) discordant for leisure time physical activity habits for thirty years. We conducted detailed health-related examinations among these twin pairs. Our main aims were to study the effects of physical activity and genes on fitness and body composition, with special reference to body fat compartments, metabolic syndrome components and related diseases and risk factor levels, status of arteries, structure and function of the heart, bone properties, and muscle and fat tissue-related mechanisms linked to physical activity and chronic disease development. Our physical activity assessments showed that inactive co-twins were on average 8.8 MET hours/day less active than their active co-twins through out their midlife (2.2 ± 2.3 vs. 11.0 ± 4.1 MET h/day, p < .001). Follow-up fitness tests showed that physically inactive co-twins were less fit than their active co-twins (estimated VO2peak 26.4 ± 4.9 vs. 32.5 ± 5.5 ml/kg/min, p < .001). Similar differences were found in both MZ and DZ pairs. On the basis of earlier epidemiological observations on nonrelated individuals, these physical activity and fitness differences are large enough to cause differences in many mechanisms and risk factors related to the development of chronic diseases and to permit future analyses.

scholarly journals Regular physical activity prevents development of left ventricular hypertrophy in hypertension

2008 ◽  
Vol 30 (2) ◽  
pp. 225-232 ◽  
Author(s):  
P. Palatini ◽  
P. Visentin ◽  
F. Dorigatti ◽  
C. Guarnieri ◽  
M. Santonastaso ◽  
...  
Keyword(s):  
Physical Activity ◽  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Regular Physical Activity

scholarly journals Self-Affirmation Promotes Physical Activity

2014 ◽  
Vol 36 (2) ◽  
pp. 217-223 ◽  
Author(s):  
Richard Cooke ◽  
Helena Trebaczyk ◽  
Peter Harris ◽  
Alison J. Wright
Keyword(s):  
Physical Activity ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Change Theory ◽  
Activity Levels ◽  
Physically Active ◽  
Positive Attitudes ◽  
Baseline Physical Activity ◽  
Activity Questionnaire

The present study tests whether a self-affirmation intervention (i.e., requiring an individual to focus on a valued aspect of their self-concept, such as honesty) can increase physical activity and change theory of planned behavior (TPB) variables linked to physical activity. Eighty young people completed a longitudinal intervention study. Baseline physical activity was assessed using the Godin Leisure-Time Physical Activity Questionnaire (LTPAQ). Next, participants were randomly allocated to either a self-affirmation or a nonaffirmation condition. Participants then read information about physical activity and health, and completed measures of TPB variables. One week later, participants again completed LTPAQ and TPB items. At follow up, self-affirmed participants reported significantly more physical activity, more positive attitudes toward physical activity, and higher intentions to be physically active compared with nonaffirmed participants. Neither attitudes nor intentions mediated the effects of self-affirmation on physical activity. Self-affirmation can increase levels of physical activity and TPB variables. Self-affirmation interventions have the potential to become relatively simple methods for increasing physical activity levels.

scholarly journals Associação entre uso de internet e manter-se ativo no lazer, estudo longitudinal EpiFloripa Idoso

2018 ◽  
Vol 20 (2) ◽  
pp. 134-145
Author(s):  
Rodrigo De Rosso Krug ◽  
André Junqueira Xavier ◽  
Eleonora D'Orsi
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Internet Use ◽  
Leisure Time ◽  
Healthy Aging ◽  
Relative Risk Ratio ◽  
Physically Active ◽  
Active Leisure ◽  
Leisure Physical Activity

The aim of this study was to verify the association between internet use and physically active leisure time during four years in older adults included in the “EpiFloripa Idoso” study, a population and longitudinal study with older adults (60+) residents in Florianópolis, Brazil, interviewed in 2009-10 (baseline) and 2013-14 (follow-up). The outcome was self-reported level of leisure physical activity, measured by the long version of the International Physical Activity Questionnaire, classified as remaining inactive; becoming inactive; becoming active; remaining active. Covariates were: gender; age (in years); per capita income in Reais; schooling (years of study); internet use longitudinally measured (remaining not using, stopping using, starting using, remaining using); and cognitive decline at baseline assessed by the Mini Mental State Examination. Relative risk ratio (RRR) adjusted by independent variables were estimated. Participants were 1,705 older adults at baseline and 1,197 at follow-up. The prevalence of remaining physically active during leisure time was 15.8% (95% CI 12.6 to 19.0) and was associated with being male (RRR = 2.14, 95% CI 1.50 to 3.05), less schooling (RRR = 0.99, 95% CI 0.99 to 0.99), starting using (RRR = 4.1, 95% CI 2.06 to 8.55) and remaining using the internet (RRR = 5.52, 95% CI 3.25 to 9.36). This study can contribute to public policies for active and healthy aging through stimulation of internet use, since this technological behavior can help increasing the level of leisure physical activity in this population.

scholarly journals Regular Physical Activity Levels and Incidence of Restrictive Spirometry Pattern: A Longitudinal Analysis of 2 Population-Based Cohorts

2020 ◽  
Vol 189 (12) ◽  
pp. 1521-1528 ◽  
Author(s):  
Anne-Elie Carsin ◽  
Dirk Keidel ◽  
Elaine Fuertes ◽  
Medea Imboden ◽  
Joost Weyler ◽  
...  
Keyword(s):  
Physical Activity ◽  
Lower Risk ◽  
Heart Diseases ◽  
Population Based ◽  
Forced Expiratory Volume ◽  
Normal Weight ◽  
Regular Physical Activity ◽  
Activity Levels ◽  
Physically Active

Abstract We estimated the association between regular physical activity and the incidence of restrictive spirometry pattern. Forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and physical activity were assessed in 2 population-based European cohorts (European Community Respiratory Health Survey: n = 2,757, aged 39–67 years; and Swiss Study on Air Pollution and Lung and Heart Diseases in Adults: n = 2,610, aged 36–82 years) first in 2000–2002 and again approximately 10 years later (2010–2013). Subjects with restrictive or obstructive spirometry pattern at baseline were excluded. We assessed the association of being active at baseline (defined as being physically active at least 2–3 times/week for ≥1 hour) with restrictive spirometry pattern at follow-up (defined as a postbronchodilation FEV1/FVC ratio of at least the lower limit of normal and FVC of &lt;80% predicted) using modified Poisson regression, adjusting for relevant confounders. After 10 years of follow-up, 3.3% of participants had developed restrictive spirometry pattern. Being physically active was associated with a lower risk of developing this phenotype (relative risk = 0.76, 95% confidence interval: 0.59, 0.98). This association was stronger among those who were overweight and obese than among those of normal weight (P for interaction = 0.06). In 2 large European studies, adults practicing regular physical activity were at lower risk of developing restrictive spirometry pattern over 10 years.

scholarly journals Evaluation of the Results of Rehabilitation of Chronic Low Back Pain Syndrome in Physically Active and Inactive Patients During Leisure Time

2020 ◽  
Vol 62 (4) ◽  
pp. 209-215
Author(s):  
Tomasz Kabała ◽  
Maciej Kabała ◽  
Czesław Giemza
Keyword(s):  
Physical Activity ◽  
Low Back Pain ◽  
Back Pain ◽  
Leisure Time ◽  
Pain Syndrome ◽  
Functional Restoration ◽  
Regular Physical Activity ◽  
Low Back ◽  
Physically Active ◽  
Functional Parameters

Introduction: Movement is one of the main, modifiable factors (behaviour-dependent) that affects the health and quality of life of individuals and the entire population. Physical activity, including evidence-based active rehabilitation, is the subject of many studies on the prevention and treatment of spinal disorders, which are some of the most serious health problems. The largest group of people with spinal disorders are patients suffering from Nonspecific Low Back Pain (ang. Nonspecific Low Back Pain – NLBP), with kinesitherapy having the widest application in the chronic pain phase. A significant part of the research is devoted to the problem of movement in patients with chronic non-specific low back pain (CNLBP). One physiotherapy treatment method used in chronic low back pain syndrome is the DBC method. It is based on a detailed functional diagnosis, answers given to a standardized questionnaire, individualized treatment plans and active exercises with spinal resistance using specialized DBC equipment. Aim: The aim of this study was to evaluate the influence of leisure-time physical activity on the results of the DBC functional restoration program in patients with chronic, non-specific, low back pain after outpatient rehabilitation. The researchers tested the hypothesis that patients with regular physical activity attained better results of functional restoration compared to physically inactive participants. M aterials and Methods: The research group was comprised of one-hundred forty-seven participants. All subjects suffered from low back pain syndrome lasting for a period of at least three months without neurological symptoms. All symptoms were non-specific. The subjects were divided into two groups. Group 1 was comprised of participants who undertake regular physical activity for more than 45-minutes per exercise session, at least twice a week. Participants in Group 2 did not undertake any physical activity other than that resulting from everyday activities. The study commenced with an interview and standardized DBC questionnaire to get participants’ subjective assessment of the following parameters: current level of pain, functional limitations and scale of depression. A clinical trial was conducted prior to the measurement of objective parameters in order to exclude radicular pain (Lasegue test). Next, the objective parameters were measured: bioelectric activity of the lumbar erector spinae muscles (ang. surfasce electromyography – sEMG) on the right and left side in two positions: standing upright and leaning forward with straight legs. Also, DBC devices were used to measure the following range of motion of the lumbo-thoracic spine: flexion, extension, rotation and lateral flexion/bending. Upon completing the tests (Test 1) both groups were subject to active DBC therapeutic treatment. The therapy consisted of 12 meetings carried out within a 6 week period. Each session lasted for 1.5 hours. When the treatments ended testing was repeated for each group (Test 2). Results: Mean values of functional parameters of the lumbar spine were calculated for both groups. Statistical significance was determined between the preliminary (Test 1) and final (Test 2) tests. All the objective parameters in Group 1 showed statistically significant improvement post-therapy. Different results were observed in Group 2 for participants who did not perform regular physical activity. Although all parameters improved, only some achieved statistical significance. Significance between the two groups was also studied at the beginning of the experiment (Test 1) and after its completion (Test 2). There results showed no statistically significant difference in values of some objective parameters prior to the treatment, while some parameters differed. The treatment achieved a statistically significant improvement in the “active” group compared to the “inactive” one in almost every tested parameter excluding the extension. Significant differences between the groups were observed in the subjective parameters such as: functional limitations (ADL) (ang. Activity of Daily Living – ADL) and level of depression both in the first and last tests. Conclusions: Patients with chronic non-specific low back pain syndrome who remain physically active in leisure time and participated in the 6-week DBC rehabilitation program achieved a statistically significant improvement in the functional parameters of the spine. Patients with chronic non-specific low back pain syndrome who remain physically active in leisure time and participated in the 6-week DBC rehabilitation program improved more in the objective and subjective functional parameters of the spine in comparison with the inactive participants. Active leisure time contributes to the efficacy of physiotherapy for people with low back disorders.

scholarly journals Cardiac Amyloidosis with Discordant QRS Voltage between Frontal and Precordial Leads

Medicina ◽  
2021 ◽  
Vol 57 (7) ◽  
pp. 660
Author(s):  
Csilla-Andrea Eötvös ◽  
Roxana-Daiana Lazar ◽  
Iulia-Georgiana Zehan ◽  
Erna-Brigitta Lévay-Hail ◽  
Giorgia Pastiu ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Cardiac Amyloidosis ◽  
Ventricular Hypertrophy ◽  
Low Voltage ◽  
Disease Process ◽  
Left Ventricular ◽  
Clinical Suspicion ◽  
Immunoglobulin Light Chain ◽  
Different Types

Among the different types, immunoglobulin light chain (AL) cardiac amyloidosis is associated with the highest morbidity and mortality. The outcome, however, is significantly better when an early diagnosis is made and treatment initiated promptly. We present a case of cardiac amyloidosis with left ventricular hypertrophy criteria on the electrocardiogram. After 9 months of follow-up, the patient developed low voltage in the limb leads, while still maintaining the Cornell criteria for left ventricular hypertrophy as well. The relative apical sparing by the disease process, as well as decreased cancellation of the opposing left ventricular walls could be responsible for this phenomenon. The discordance between the voltage in the frontal leads and precordial leads, when present in conjunction with other findings, may be helpful in raising the clinical suspicion of cardiac amyloidosis.

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