Abstract P142: Metabolically Healthy Obesity In A Young Adult Population Provided By A Primary Healthcare Center In Brazil (LAPARC Study)

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Beatriz D Marinho ◽  
Tomás de Souza Mello ◽  
Rafael B Azevedo ◽  
Daniella Barbalho ◽  
Clara Muguet ◽  
...  

Background: Obesity is increasing in younger populations, and is associated with a high cardiovascular (CV) risk, however, it is not clear whether metabolically healthy obesity (MHO) may have a lower CV risk or if it is just an earlier stage of the disease. Objective: To evaluate the prevalence and CV risk factors associated with MHO in a young adult population provided by a Primary Healthcare Center in a large urban area of Brazil. Methods: A cross-sectional population study for CV risk assessment in adults aged 20-50 years old provided by a Primary Healthcare Center in Rio de Janeiro, Brazil. Demographic, anthropometric data and CV risk factors were recorded. All underwent office blood pressure (OBP) measurements, laboratory evaluation (lipid and glycemic profile). Obesity was defined as a BMI ≥ 30 kg/m2 and MHO are those who have less than 3 of the following criteria: hypertension, diabetes, total cholesterol ≥ 200 mg/dL, HDL<40 mg/dL (men) and 50 mg/dL (women), triglycerides>150 mg/dL and increased waist circumference. Results: A total of 632 individuals were evaluated (60% female; mean age 37 ± 9 years). The prevalence of obesity was 25% (161 of 632 individuals), of which 73% (117 of 161 individuals) were classified as MHO. Obese individuals are older, with a higher prevalence of physical inactivity (51% vs 41%, p=0.03), hypertension (44% vs 19%, p<0.001), dyslipidemia (50% vs 36%, p=0.002) and diabetes (7% vs 2%, p=0.001) with higher systolic OBP. MHO compared to unhealthy ones are significantly younger and smoke less. Despite being obese, they have lower BMI (33.6 vs 35.2 kg/m2, p=0.02) and abdominal circumference (102 vs 110 cm, p=0.03), with lower diastolic BP. Conclusions: MHO was more prevalent in this young adult population and seems to have a lower CV risk, however it is not clear whether these younger and less obese individuals are only at an earlier stage of the disease. Perhaps the CV diseases onset is postponed for a few years. Even so, these individuals should not be excluded from public health policies as a form of primary prevention.

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Tomás de Souza Mello ◽  
Beatriz D Marinho ◽  
Rafael B Azevedo ◽  
Lucas Antequera ◽  
Pedro Julio Velasco ◽  
...  

Objective: To evaluate the relationship between the main cardiovascular (CV) risk factors and socioeconomic indicators in a population of young adults provided by a Primary Healthcare Center in a large urban area of Brazil. Methods: Cross-sectional population study that included adults aged between 20- and 50-years old provided by a Primary Healthcare Center in Rio de Janeiro, Brazil. Demographic data (gender and age), socioeconomic data (education level, occupation, employment), CV risk factors (smoking, sedentary lifestyle, obesity, hypertension, diabetes, dyslipidemia) were recorded. The metabolic profile was evaluated through laboratory tests. Those who studied up to high school were considered poorly educated. Results: A total of 604 individuals were enrolled [39% male, mean age: 38.8 ± 8,9 years]. The median of schooling was 12 years. In addition, 288 individuals had high schooling, of which 44.5% were male. A total of 130 individuals did not study or work. Women with low education had a higher risk of smoking, hypertension, and obesity, with no difference regarding labor or study activities. Otherwise, men with low education had higher risk of sedentary lifestyle and hypertension. Among men, not working or studying increased the risk of smoking and hypertension. Conclusions: We found an inverse association between socioeconomic status and the prevalence of CV risk factors. Women are more affected by low schooling, while men are more affected by their working occupation. The study suggests that socioeconomic factors influence the CV risk, affecting men and women differently, pointing to the need for public policies to reverse this situation.


Healthcare ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1548
Author(s):  
Jose Miguel Baena-Díez ◽  
Isabel Gonzalez-Casafont ◽  
Sara Cordeiro-Coelho ◽  
Soledad Fernández-González ◽  
Migdalia Rodríguez-Jorge ◽  
...  

Improved technology facilitates the acceptance of telemedicine. The aim was to analyze the effectiveness of telephone follow-up to detect severe SARS-CoV-2 cases that progressed to pneumonia. A prospective cohort study with 2-week telephone follow-up was carried out March 1 to May 4, 2020, in a primary healthcare center in Barcelona. Individuals aged ≥15 years with symptoms of SARS-CoV-2 were included. Outpatients with non-severe disease were called on days 2, 4, 7, 10 and 14 after diagnosis; patients with risk factors for pneumonia received daily calls through day 5 and then the regularly scheduled calls. Patients hospitalized due to pneumonia received calls on days 1, 3, 7 and 14 post-discharge. Of the 453 included patients, 435 (96%) were first attended to at a primary healthcare center. The 14-day follow-up was completed in 430 patients (99%), with 1798 calls performed. Of the 99 cases of pneumonia detected (incidence rate 20.8%), one-third appeared 7 to 10 days after onset of SARS-CoV-2 symptoms. Ten deaths due to pneumonia were recorded. Telephone follow-up by a primary healthcare center was effective to detect SARS-CoV-2 pneumonias and to monitor related complications. Thus, telephone appointments between a patient and their health care practitioner benefit both health outcomes and convenience.


2014 ◽  
Vol 235 (2) ◽  
pp. e286-e287
Author(s):  
J. Canilho ◽  
A.C. Alves ◽  
Q. Rato ◽  
M. Bourbon

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Rafael Bellotti Azevedo ◽  
Beatriz Deberaldini Marinho ◽  
Tomás de Souza Mello ◽  
Bruna Gopp Botelho ◽  
João Victor Gonçalves de Hollanda ◽  
...  

Introduction: Dyslipidemia, Glucose Intolerance (GI), Diabetes Mellitus (DM), and Metabolic Syndrome (MS) are metabolic conditions often asymptomatic and related to high cardiovascular (CV) morbidity and mortality. Nonetheless, these conditions are not commonly screened in younger adults. The LapARC cohort Study is a population-based study to assess CV risk profile in a young adult population. Objective: To evaluate the prevalence of dyslipidemia, DM, GI, and MS in a young adult population enrolled in the Family Health Strategy (FHS) in the center of Rio de Janeiro, Brazil. Methods: Cross-sectional population study that enrolled individuals aged 20-50 years registered in an FHS unit in Rio de Janeiro. Sociodemographic, anthropometric characteristics, and CV risk factors were recorded. Office blood pressure (BP) was obtained by the average of 2 measurements obtained on two different occasions. All participants underwent laboratory evaluation (lipid and glycemic profile) and home blood pressure monitoring (HBPM). Two screening questionnaires for obstructive sleep apnea (OSA): STOP-BANG (SBQ) and Epworth Sleepiness Scale (ESS) were applied. Results: We evaluated 575 individuals [39% male gender; average age: 39.9 ± 8.7 years old]. The most common modifiable CV risk factors were physical inactivity (43.0%), and obesity (25.0%). The prevalence of dyslipidemia was 57.6%. These individuals had a higher prevalence of male gender (42.0% vs 34.0%), MS (25.0% vs 4.0%), and high risk for OSA by ESS (35.0% vs 27%). A total of 91 individuals (15.8%) were diagnosed with MS, being predominantly males (52.0% vs 36.0%), older and obese (46.0% vs 21.0%), with a higher prevalence of dyslipidemia (90.0% vs 52.0%), GI (20.0% vs 5.0%), hypertension (63.0% vs 18.0%) with uncontrolled office and Home BP. They also had a high risk for OSA by SBQ and ESS (25.0% vs 8.0%). Moreover, a total of 55 (9.6%) subjects presented an altered glycemic profile. These individuals were older with a higher prevalence of obesity (38.0% vs 24.0%), hypertension (36.0% vs 23.0%), uncontrolled HBPM (22.0% vs 12.0%) and MS (29.0% vs 13.0%) when compared to normoglycemic patients. Conclusion: This young and apparently healthy population has an adverse cardiometabolic profile, indicating the importance of precocious CV risk stratification. Thus, efficient primary preventive strategies can be implemented to reduce the probability of CV disease development in the future.


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