Abstract WMP90: Marital Status and Post-Stroke Outcomes

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Liming Dong ◽  
Devin Brown ◽  
Erin Case ◽  
Lewis Morgenstern ◽  
Lynda Lisabeth

Introduction: Although the impacts of marital status on health have long been recognized, little is known about its role in stroke outcomes. The study examined the association of marital status with neuropsychiatric, cognitive, functional, and quality of life outcomes at 90 days post-stroke in a population-based sample. Methods: Data were obtained from the Brain Attack Surveillance in Corpus Christi (BASIC) project (2009-2016). Post-stroke outcomes included neurological status assessed by the National Institutes of Health Stroke Scale, cognitive function assessed by the Modified Mini-Mental State Examination, functioning assessed by an activities of daily living (ADL)/instrumental activities of daily living (IADL) score, depression assessed by the 8-item Patient Health Questionnaire, and quality of life assessed by the short-form Stroke Specific Quality of Life scale. Linear or Tobit regression models were used to examine the association between marital status and stroke outcomes, accounting for attrition. Results: Among 1,226 ischemic or hemorrhagic cases, mean age was 67.6 (SD=12.3), half were women, and three-fifths were Mexican American; 23.0% were widowed, 20.1% were divorced/separated, and 8.4% were never married. Widowed participants were more likely to be female, aged above 75, and less educated than other groups. After adjustment for age, sex, ethnicity, education and stroke severity, compared with those married, those widowed had significantly worse cognitive function and quality of life, those never married had worse neurological and cognitive outcomes, and those divorced/separated had more depressive symptoms and poorer quality of life (Table). Conclusions: Being unmarried at stroke onset is associated with worse outcomes after stroke, and the outcome profiles vary by marital status. Further research should investigate potential mechanisms and develop interventions to improve outcomes of unmarried stroke survivors.

Author(s):  
Wei Yu ◽  
Jie Tong ◽  
Xirong Sun ◽  
Fazhan Chen ◽  
Jie Zhang ◽  
...  

Background: Factors related to medication adherence in patients with schizophrenia have always been key to the treatment and rehabilitation of these patients. However, the treatment modes in different countries are not the same, and there is no research on the factors influencing medication adherence under different mental health service modes. Objectives: The purpose of this study was to explore medication adherence and its influencing factors in patients with schizophrenia in the Chinese institutional environment. Methods: We conducted a cross-sectional study of hospitalized persons living with schizophrenia from November 2018 to January 2019. A systematic sampling method was used to select 217 hospitalized persons living with schizophrenia. The Medication Adherence Rating Scale (MARS), Positive and Negative Syndrome Scale (PANSS), General Self-Efficacy Scale (GSES), Schizophrenia Quality of Life Scale (SQLS), and Scale of Social Skills for Psychiatric Inpatients (SSPI) were used to explore medication compliance and its influencing factors in the Chinese institutional environment. Results: The descriptive analysis and ANOVA showed that there were no significant differences in medication adherence when assessed by demographic characteristics such as sex, marital status, and education level (p > 0.05). A correlation analysis showed that there was no significant correlation between medication adherence and mental symptoms (p > 0.05) but that there was a positive correlation with self-efficacy, quality of life, and activities of daily living (p < 0.01). The linear regression analysis showed that self-efficacy, psychosocial factors, symptoms/side effects, and activities of daily living had significant effects on medication adherence (F = 30.210, p < 0.001). Conclusions: Our findings show that the self-efficacy, quality of life, and social function of patients with schizophrenia are important self-factors influencing medication adherence in the Chinese institutional environment.


2002 ◽  
Vol 8 (5) ◽  
pp. 372-376 ◽  
Author(s):  
C R Nicholl ◽  
N B Lincoln ◽  
E D Playford

Objective: To investigate whether the Nottingham Extended Activities of Daily Living Scale (EADL) is reliable and valid for the assessment of disability in patients with multiple sclerosis (MS). Design: Questionnaire measures were administered on two occasions four months apart. Subjects: A total of 240 patients recruited through a randomized controlled trial of cognitive assessment and treatment in MS. Measures: The Nottingham EADL, Guys Neurological Disability Scale (GNDS) and SF-36 quality of life scale. Results: The EADL items did not form a Guttman Scale (CR 0.8, CS 0.3). The EADL and its four subscales all had high internal consistency (α 0.72-0.94). Test-retest reliability was satisfactory (rs 0.81-0.90) with a mean difference in scores on the two occasions of 0.29. Factor analysis generally supported the subscale structure. There were significant but weak correlations with quality of life measures. Conclusions: The EADL shows promise for the assessment of disability in MS, but the range of items needs to be extended. Further evaluation of the scale seems warranted.


2020 ◽  
Author(s):  
Yao He ◽  
Yuling Tian ◽  
Hongjuan Han ◽  
Jing Cui ◽  
Xiaoyan Ge ◽  
...  

Abstract Background: Research on quality of life (QOL) with Parkinson’s disease (PD) has examined direct influencing factors, not mediators. The study aim was to explore whether PD severity and poor cognitive function may decrease physical and mental QOL by reducing activities of daily living (ADL) and increasing depression in sequence. Methods: We conducted a cross-sectional questionnaire study of 150 PD hospital patients in China. PD severity, cognitive function, ADL, depression, and QOL were evaluated. We used structural equation modeling to analyze the mediating effects of ADL and depression on the association between PD severity/cognition and physical (PCS) and mental (MCS) QOL. Results:There was a significant mediating effect of PD severity on PCS via ADL and depression (95%CI: −0.669, −0.026), and a significant direct effect (p<0.001). The mediating effect of PD severity on MCS via ADL and depression was significant (95%CI: −2.135, −0.726), but there was no direct effect (p = 0.548). There was a significant mediating effect of cognitive function on PCS via ADL and depression (95%CI: 0.025, 0.219) and a significant direct effect (p<0.001). The mediating effect of cognitive function on MCS via ADL and depression was significant (95%CI: 0.256, 0.645), but there was no direct effect (p = 0.313). The PCS models showed a partial mediation, and the MCS models showed a complete mediation, of ADL and depression.Conclusions:PD severity and cognitive function increase depression by reducing ADL, leading to lower QOL, and directly or indirectly affect PCS and MCS through different pathways.


Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000011988
Author(s):  
Eric L. Stulberg ◽  
Erica Twardzik ◽  
Sehee Kim ◽  
Chia-Wei Hsu ◽  
Yuliang Xu ◽  
...  

Objective:To examine associations between neighborhood socioeconomic status (nSES) and 90-day post-stroke outcomes.Methods:The Brain Attack Surveillance in Corpus Christi Project is a population-based surveillance study in Nueces County, Texas. Stroke patients were identified between 2010 and 2016 via active and passive surveillance and enrolled in the study. nSES index is a standardized composite of 2010 census-tract level income, wealth, education, and employment (median -4.56; IQR: -7.48 to -0.46). 90-day outcomes were ascertained via interview: functional status measured by the average of 22 activities of daily living/instrumental activities of daily living (range 1-4), biopsychosocial health by the Stroke-Specific Quality of Life scale (range 0-5), and depressive symptoms by the 8-item Patient Health Questionnaire (range 0-24). Associations between nSES and outcomes were estimated using confounder-adjusted generalized estimating equations with an nSES*National Institute of Health Stroke Scale interaction term.Results:776 survivors composed the analytic sample (52.96% male, 62.24% Mexican-American, 52.96% ≥ 64 years-old). Higher compared to lower nSES (mean difference comparing 75th to 25th percentile of nSES ) was associated with better function (-0.27, 95% CI: -0.49, -0.05), better biopsychosocial health (0.26, 95% CI: 0.06, 0.47), and less depressive symptoms (-1.77, 95% CI: -3.306, -0.48) among those with moderate-to-severe strokes. Among those with minor strokes, higher nSES was associated with better function (-0.13; 95% CI: -0.24, -0.02).Conclusions: nSES may influence post-stroke recovery. Studies should identify neighborhood characteristics that contribute to post-stroke outcomes, particularly in moderate-to-severe stroke survivors.


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Ina Shaw ◽  
Melany Cronje ◽  
Brandon Stuwart Shaw

Background: Exercise is related to enhanced cognitive functioning and brain plasticity. Exercise might represent a potential adjunctive treatment for neuropsychiatric disorders, such as Alzheimer's disease (AD). Furthermore, group exercise may prove especially useful due to its additional benefits. Objectives: This study aimed to determine the effect of low-cost, group-based exercise on mental outcomes in patients with mild to moderate AD. Methods: Participants with mild to moderate AD were randomized to either a non-exercising control (CON) group or a group-exercise (GEX) group (n = 20 each). The GEX participated in eight weeks of three-times-weekly non-consecutive 45-minute sessions consisting of balance, resistance, aerobic, and flexibility exercises to determine their effect on mental outcomes, namely, cognitive function, activities of daily living (ADLs), and quality of life (QOL). Results: The intervention program showed a significant (P ≤ 0.05) increase in Mini-Mental State Examination (MMSE) scores (P = 0.023). While the GEX were found to have no change in their (Alzheimer’s disease cooperative study activities of daily living) ADCS-ADL scores (P = 0.574). The CON demonstrated a significant, but deleterious 13.77% decrease in their ADCS-ADL scores from pre- to mid-test (P = 0.023) and from pre- to post-test (P = 0.038). Quality of Life-Alzheimer’s Disease (QOL-AD) scores were unchanged in both the GEX and CON. Conclusions: Our results indicate that a low-cost, multidimensional group exercise intervention can positively influence cognitive function and improve patients with mild to moderate AD ability to perform ADLs.


2006 ◽  
Vol 9 ◽  
pp. e25-e43 ◽  
Author(s):  
Gunilla Borglin ◽  
Ylva Hellström ◽  
Bo Hagberg ◽  
Anna-Karin Edberg ◽  
Albert Westergren ◽  
...  

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