Parameters of Spike Trains Observed in a Short Time Window

2008 ◽  
Vol 20 (5) ◽  
pp. 1325-1343 ◽  
Author(s):  
Zbyněk Pawlas ◽  
Lev B. Klebanov ◽  
Martin Prokop ◽  
Petr Lansky

We study the estimation of statistical moments of interspike intervals based on observation of spike counts in many independent short time windows. This scenario corresponds to the situation in which a target neuron occurs. It receives information from many neurons and has to respond within a short time interval. The precision of the estimation procedures is examined. As the model for neuronal activity, two examples of stationary point processes are considered: renewal process and doubly stochastic Poisson process. Both moment and maximum likelihood estimators are investigated. Not only the mean but also the coefficient of variation is estimated. In accordance with our expectations, numerical studies confirm that the estimation of mean interspike interval is more reliable than the estimation of coefficient of variation. The error of estimation increases with increasing mean interspike interval, which is equivalent to decreasing the size of window (less events are observed in a window) and with decreasing the number of neurons (lower number of windows).

2011 ◽  
Vol 19 ◽  
pp. S113
Author(s):  
M.E. van Meegeren ◽  
N.W. Jansen ◽  
G. Roosendaal ◽  
S.C. Mastbergen ◽  
F.P. Lafeber

1998 ◽  
Vol 1644 (1) ◽  
pp. 142-149 ◽  
Author(s):  
Gang-Len Chang ◽  
Xianding Tao

An effective method for estimating time-varying turning fractions at signalized intersections is described. With the inclusion of approximate intersection delay, the proposed model can account for the impacts of signal setting on the dynamic distribution of intersection flows. To improve the estimation accuracy, the use of preestimated turning fractions from a relatively longer time interval has been proposed to serve as additional constraints for the same estimation but over a short time interval. The results of extensive simulation experiments indicated that the proposed method can yield sufficiently accurate as well as efficient estimation of dynamic turning fractions for signalized intersections.


2020 ◽  
pp. 5-13
Author(s):  
Vishal Dubey ◽  
◽  
◽  
◽  
Bhavya Takkar ◽  
...  

Micro-expression comes under nonverbal communication, and for a matter of fact, it appears for minute fractions of a second. One cannot control micro-expression as it tells about our actual state emotionally, even if we try to hide or conceal our genuine emotions. As we know that micro-expressions are very rapid due to which it becomes challenging for any human being to detect it with bare eyes. This subtle-expression is spontaneous, and involuntary gives the emotional response. It happens when a person wants to conceal the specific emotion, but the brain is reacting appropriately to what that person is feeling then. Due to which the person displays their true feelings very briefly and later tries to make a false emotional response. Human emotions tend to last about 0.5 - 4.0 seconds, whereas micro-expression can last less than 1/2 of a second. On comparing micro-expression with regular facial expressions, it is found that for micro-expression, it is complicated to hide responses of a particular situation. Micro-expressions cannot be controlled because of the short time interval, but with a high-speed camera, we can capture one's expressions and replay them at a slow speed. Over the last ten years, researchers from all over the globe are researching automatic micro-expression recognition in the fields of computer science, security, psychology, and many more. The objective of this paper is to provide insight regarding micro-expression analysis using 3D CNN. A lot of datasets of micro-expression have been released in the last decade, we have performed this experiment on SMIC micro-expression dataset and compared the results after applying two different activation functions.


2018 ◽  
Vol 21 (10) ◽  
pp. 979-984 ◽  
Author(s):  
Chiara Adami ◽  
Elena Lardone ◽  
Paolo Monticelli

Objectives The aim of this study was to compare the Electronic von Frey Anaesthesiometer (EVF) and the Small Animal ALGOmeter (SMALGO), used to measure sensory thresholds in 13 healthy cats at both the stifle and the lumbosacral joint, in terms of inter-rater and inter-device reliability. Methods Two independent observers carried out the sets of measurements in a randomised order, with a 45 min interval between them, in each cat. The inter-rater and inter-device reliability were evaluated by calculating the inter-rater correlation coefficient (ICC) for each pair of measurements. The Bland–Altman method was used as an additional tool to assess the level of agreement between the two algometers. Results The mean ± SD sensory thresholds measured with the EVF were 311 ± 116 g and 378 ± 178 g for the stifle and for the lumbosacral junction, respectively, whereas those measured with the SMALGO were 391 ±172 g and 476 ± 172 g. The inter-rater reliability was fair (ICC >0.4) for each pair of measurements except those taken at the level of the stifle with the SMALGO, for which the level of agreement between observers A and B was poor (ICC = 0.01). The inter-device reliability was good (ICC = 0.73; P = 0.001). The repetition of the measurements affected reliability, as the thresholds obtained after the 45 min break were consistently lower than those measured during the first part of the trial ( P = 0.02). Conclusions and relevance The EVF and the SMALGO may be used interchangeably in cats, especially when the area to be tested is the lumbosacral joint. However, when the thresholds are measured at the stifle, the inter-observer reliability is better with the EVF than with the SMALGO. The reliability decreases when the measurements are repeated within a short time interval, suggesting a limited clinical applicability of quantitative sensory testing with both algometers in cats.


1989 ◽  
Vol 21 (1) ◽  
pp. 1-19 ◽  
Author(s):  
H. R. Lerche ◽  
D. Siegmund

Let T be the first exit time of Brownian motion W(t) from a region ℛ in d-dimensional Euclidean space having a smooth boundary. Given points ξ0 and ξ1 in ℛ, ordinary and large-deviation approximations are given for Pr{T < ε |W(0) = ξ0, W(ε) = ξ 1} as ε → 0. Applications are given to hearing the shape of a drum and approximating the second virial coefficient.


2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S293-S293
Author(s):  
Jonathan Altamirano ◽  
Grace Tam ◽  
Marcela Lopez ◽  
India Robinson ◽  
Leanne Chun ◽  
...  

Abstract Background While pediatric cases of COVID-19 are at low risk for adverse events, schoolchildren should be considered for surveillance as they can become infected at school and serve as sources of household or community transmission. Our team assessed the feasibility of young children self-collecting SARS-CoV-2 samples for surveillance testing in an educational setting. Methods Students at a K-8 school were tested weekly for SARS-CoV-2 from September 2020 - June 2021. Error rates were collected from September 2020 - January 2021. Clinical staff provided all students with instructions for anterior nares specimen self-collection and then observed them to ensure proper technique. Instructions included holding the sterile swab while making sure not to touch the tip, inserting the swab into their nostril until they start to feel resistance, and rubbing the swab in four circles before repeating the process in their other nostril. An independent observer timed random sample self-collections from April - June 2021. Results 2,590 samples were collected from 209 students during the study period when data on error rates were collected. Errors occurred in 3.3% of all student encounters (n=87). Error rates over time are shown in Figure 1, with the highest rate occurring on the first day of testing (n=20/197, 10.2%) and the lowest in January 2021 (n=1/202, 0.5%). 2,574 visits for sample self-collection occurred during the study period when independent timing data was collected (April - June 2021). Of those visits, 7.5% (n=193) were timed. The average duration of each visit was 70 seconds. Figure 1. Swab Error Rates Over Time Conclusion Pediatric self-collected lower nasal swabs are a viable and easily tolerated specimen collection method for SARS-CoV-2 surveillance in school settings, as evidenced by the low error rate and short time window of sample self-collection during testing. School administrators should expect errors to drop quickly after implementing testing. Disclosures All Authors: No reported disclosures


Author(s):  
Laura Mitrea ◽  
Bernadette-Emoke Teleky ◽  
Loredana-Florina Leopold ◽  
Silvia-Amalia Nemes ◽  
Diana Plamada ◽  
...  

Author(s):  
Victor Birman ◽  
Sarp Adali

Abstract Active control of orthotropic plates subjected to an impulse loading is considered. The dynamic response is minimized using in-plane forces or bending moments induced by piezoelectric stiffeners bonded to the opposite surfaces of the plate and placed symmetrically with respect to the middle plane. The control forces and moments are activated by a piece-wise constant alternating voltage with varying switch-over time intervals. The magnitude of voltage is bounded while the switch-over time intervals are constantly adjusted to achieve an optimum control. Numerical examples presented in the paper demonstrate the effectiveness of the method and the possibility of reducing the vibrations to very small amplitudes within a short time interval which is in the order of a second.


Development ◽  
2002 ◽  
Vol 129 (20) ◽  
pp. 4785-4796 ◽  
Author(s):  
Jean-Baptiste Charrier ◽  
Françoise Lapointe ◽  
Nicole M. Le Douarin ◽  
Marie-Aimée Teillet

Molecular analysis carried out on quail-chick chimeras, in which quail Hensen’s node was substituted for its chick counterpart at the five- to six-somite stage (ss), showed that the floor plate of the avian neural tube is composed of distinct areas: (1) a median one (medial floor plate or MFP) derived from Hensen’s node and characterised by the same gene expression pattern as the node cells (i.e. expression of HNF3β and Shh to the exclusion of genes early expressed in the neural ectoderm such as CSox1); and (2) lateral regions that are differentiated from the neuralised ectoderm (CSox1 positive) and form the lateral floor plate (LFP). LFP cells are induced by the MFP to express HNF3β transiently, Shh continuously and other floor-plate characteristic genes such as Netrin. In contrast to MFP cells, LFP cells also express neural markers such as Nkx2.2 and Sim1. This pattern of avian floor-plate development presents some similarities to floor-plate formation in zebrafish embryos. We also demonstrate that, although MFP and LFP have different embryonic origins in normal development, one can experimentally obtain a complete floor plate in the neural epithelium by the inductive action of either a notochord or a MFP. The competence of the neuroepithelium to respond to notochord or MFP signals is restricted to a short time window, as only the posterior-most region of the neural plate of embryos younger than 15 ss is able to differentiate a complete floor plate comprising MFP and LFP. Moreover, MFP differentiation requires between 4 and 5 days of exposure to the inducing tissues. Under the same conditions LFP and SHH-producing cells only induce LFP-type cells. These results show that the capacity to induce a complete floor plate is restricted to node-derived tissues and probably involves a still unknown factor that is not SHH, the latter being able to induce only LFP characteristics in neuralised epithelium.


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