Surface modification of the polymers present in a polysulfone hollow fiber hemodialyser by covalent binding of heparin or endothelial cell surface heparan sulfate: Flow characteristics and platelet adhesion

2000 ◽  
Vol 11 (3) ◽  
pp. 245-272 ◽  
Author(s):  
H. Baumann ◽  
A. Kokott
Keyword(s):  
Surface Modification ◽  
Endothelial Cell ◽  
Cell Surface ◽  
Heparan Sulfate ◽  
Hollow Fiber ◽  
Platelet Adhesion ◽  
Covalent Binding ◽  
Flow Characteristics ◽  
Endothelial Cell Surface

scholarly journals Surface modification of hydrophobic polymers for improvement of endothelial cell-surface interactions

1992 ◽  
Vol 11 (1-4) ◽  
pp. 157-162 ◽  
Author(s):  
A. Dekker ◽  
K. Reitsma ◽  
T. Beugeling ◽  
A. Bantjes ◽  
J. Feijen ◽  
...  
Keyword(s):  
Surface Modification ◽  
Endothelial Cell ◽  
Cell Surface ◽  
Surface Interactions ◽  
Endothelial Cell Surface ◽  
Hydrophobic Polymers ◽  
Cell Surface Interactions

scholarly journals High-resolution probing heparan sulfate–antithrombin interaction on a single endothelial cell surface: single-molecule AFM studies

2015 ◽  
Vol 17 (20) ◽  
pp. 13301-13306 ◽  
Author(s):  
Cunlan Guo ◽  
Xian Fan ◽  
Hong Qiu ◽  
Wenyuan Xiao ◽  
Lianchun Wang ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
High Resolution ◽  
Cell Surface ◽  
Heparan Sulfate ◽  
Single Molecule ◽  
Binding Sites ◽  
Specific Interactions ◽  
Endothelial Cell Surface ◽  
Afm Probe

Using an antithrombin functionalized AFM probe, the specific interactions between antithrombin and heparan sulfate on endothelial cell surface were determined, revealing previously unexpected diverse binding sites as well as critical roles of N-, 2-O- and 6-O-sulfation in the interactions.

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