Role of Rapid On-Site Cytological Evaluation (ROSE) in Diagnosis of Lung Cancer: A Single Institution Experience

2019 ◽  
Author(s):  
E. Kamberi ◽  
T. Pieramici ◽  
G.P. Mattioli ◽  
A. Filosa ◽  
G. Riccioni ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Single Institution ◽  
Cytological Evaluation ◽  
Diagnosis Of Lung Cancer

Diagnostic role of liquid-based cytology of bronchial lavage fluid in addition to bronchial brushing specimens in lung cancer

2020 ◽  
pp. 030089162096021
Author(s):  
Chao Cao ◽  
Xuechan Yu ◽  
Tingting Zhu ◽  
Qingwen Jiang ◽  
Yiting Li ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lavage Fluid ◽  
False Negatives ◽  
Predictive Values ◽  
Bronchial Brushing ◽  
Diagnostic Role ◽  
Thin Layer Method ◽  
Liquid Based Cytology ◽  
Diagnosis Of Lung Cancer

Background: Liquid-based cytology (LBC) tests, including the liquid-based thin layer method, have demonstrated the highest potential for reducing false-negatives and improving sample quality. Method: This study aimed to evaluate the diagnostic role of LBC of bronchial brushing specimens in lung cancer. A total of 249 patients were analyzed in our study, involving 155 patients with combined bronchial brushing and bronchoalveolar lavage (BAL) and 94 patients with BAL alone. Results: The sensitivity in the combined bronchial brushing and BAL group was 61.4% in the diagnosis of lung cancer, which is much higher than with BAL alone. Rates of positive predictive values and negative predictive values in the combined group compared with the BALF alone group were 98.6% vs 100% and 47.6% vs 37.4%, respectively. Sensitivity in the BALF alone group was 12.5% in bronchoscopically invisible pulmonary lesions and as high as 52.1% in the combined group. Conclusion: The results from our study demonstrated that LBC of brushing samples could be used as an important complement of bronchoscopy and could have the potential to be widely applied.

Role of Percutaneous Fine Needle Aspiration in the Diagnosis of Lung Cancer: Our Experience with 140 Patients

Oncology ◽  
1983 ◽  
Vol 40 (3) ◽  
pp. 177-180 ◽  
Author(s):  
Corrado Gallo Curcio ◽  
Massimo Rinaldi ◽  
Riccardo Tonachella ◽  
Raffaele Perrone Donnorso
Keyword(s):  
Lung Cancer ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Diagnosis Of Lung Cancer

scholarly journals Role of a serum-based biomarker panel in the early diagnosis of lung cancer for a cohort of high-risk patients

Cancer ◽  
2015 ◽  
Vol 121 (S17) ◽  
pp. 3113-3121 ◽  
Author(s):  
Da-Wei Yang ◽  
Yong Zhang ◽  
Qun-Ying Hong ◽  
Jie Hu ◽  
Chun Li ◽  
...  
Keyword(s):  
Lung Cancer ◽  
High Risk ◽  
Early Diagnosis ◽  
High Risk Patients ◽  
Biomarker Panel ◽  
Risk Patients ◽  
Diagnosis Of Lung Cancer

Role of Transesophageal Endosonography-Guided Fine-Needle Aspiration in the Diagnosis of Lung Cancer

CHEST Journal ◽  
2000 ◽  
Vol 117 (2) ◽  
pp. 339-345 ◽  
Author(s):  
Annette Fritscher-Ravens ◽  
Nib Soehendra ◽  
Parupudi V.J. Sriram ◽  
Lars Schirrow ◽  
Andreas Meyer ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Diagnosis Of Lung Cancer

scholarly journals Role of minimal panel immunostaining in accurate diagnosis of lung cancer using small biopsies

2017 ◽  
Vol 66 (2) ◽  
pp. 307-312
Author(s):  
Manar Ahmed Abdel Rahman ◽  
Nadia Abdel Moneim Nada ◽  
Khaled Refaat Zalata ◽  
Mohammad Khairy El Badrawy ◽  
Iman Mohammed El Salkh ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Accurate Diagnosis ◽  
Diagnosis Of Lung Cancer

scholarly journals Exosomes and the role of exosomal miRNA in the diagnosis of lung cancer

2021 ◽  
Vol 136 (3) ◽  
pp. 51-63
Author(s):  
R.I. Bersimbaev ◽  
◽  
O.V. Bulgakova ◽  
A.A. Aripova ◽  
A.Zh. Kausbekova ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Types ◽  
Current Data ◽  
Expression Of Genes ◽  
Diagnostic Potential ◽  
Oncological Diseases ◽  
Diagnosis Of Lung Cancer ◽  
The Moment ◽  
Almost All

Exosomes are extracellular vesicles secreted by almost all cell types that can function as a cell-to-cell carrier of information, providing pleiotropic functions in intercellular communication. Exosomes can transport various biomolecules, including proteins and nucleic acids, into recipient cells. The review analyzed the current data on the role of exosomes and the possibility of using exosomal microRNAs as a biomarker in the diagnosis of lung cancer. MicroRNAs can act as oncogenes or tumor suppressors, so they can regulate the expression of genes that play an important role in oncogenesis. At the moment, microRNAs of exosomes are one of the main candidates for the role of molecular markers in liquid biopsy for the diagnosis of oncological diseases. The review analyzes the diagnostic potential of the use of exosomes in carcinogenesis in general, with an emphasis on the use of exosomal microRNAs as biomarkers of lung cancer.

Sign in / Sign up

Export Citation Format

Share Document