Regulatory T Cells Subvert Mycobacterial Containment in Patients Failing Extensively Drug-Resistant Tuberculosis Treatment

2018 ◽  
Vol 198 (1) ◽  
pp. 104-116 ◽  
Author(s):  
Malika Davids ◽  
Anil S. Pooran ◽  
Elize Pietersen ◽  
Helen C. Wainwright ◽  
Anke Binder ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Tuberculosis Treatment ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Extensively Drug Resistant

scholarly journals Emergence of Low-level Delamanid and Bedaquiline Resistance During Extremely Drug-resistant Tuberculosis Treatment

2019 ◽  
Vol 69 (7) ◽  
pp. 1229-1231 ◽  
Author(s):  
Silke Polsfuss ◽  
Sabine Hofmann-Thiel ◽  
Matthias Merker ◽  
David Krieger ◽  
Stefan Niemann ◽  
...  
Keyword(s):  
Multidrug Resistant ◽  
New Drugs ◽  
Tuberculosis Treatment ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Low Level ◽  
Resistant Tuberculosis ◽  
Extensively Drug Resistant

Abstract Two new drugs, delamanid and bedaquiline, have recently been approved for treatment of multidrug-resistant and extensively drug-resistant (XDR) tuberculosis. Here, we report a case of clofazimine, bedaquiline, and low-level delamanid resistances acquired during treatment of a patient with XDR tuberculosis.

scholarly journals Consensus Not Yet Reached on Key Drugs for Extensively Drug‐Resistant Tuberculosis Treatment

2009 ◽  
Vol 49 (2) ◽  
pp. 315-316 ◽  
Author(s):  
Giovanni Battista Migliori ◽  
Giovanni Sotgiu ◽  
M. D’Arcy Richardson ◽  
Rosella Centis ◽  
Gunar Guenther ◽  
...  
Keyword(s):  
Tuberculosis Treatment ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Extensively Drug Resistant

scholarly journals Mental disorders and drug/alcohol use in patients commencing extensively drug-resistant tuberculosis treatment

2017 ◽  
Vol 7 (3) ◽  
pp. 237-239 ◽  
Author(s):  
J. Scuffell ◽  
D. Boccia ◽  
F. Garcia Velarde ◽  
S. R. Leon ◽  
G. Raviola ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Mental Disorders ◽  
Tuberculosis Treatment ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Extensively Drug Resistant
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