Association of Genetic Variants in Alcohol Dehydrogenase 4 With Alcohol Dependence in Brazilian Patients

2005 ◽  
Vol 162 (5) ◽  
pp. 1005-1007 ◽  
Author(s):  
Camila Guindalini ◽  
Sandra Scivoletto ◽  
Ricardo G.M. Ferreira ◽  
Gerome Breen ◽  
Monica Zilberman ◽  
...  
Keyword(s):  
Alcohol Dehydrogenase ◽  
Alcohol Dependence ◽  
Genetic Variants

scholarly journals Genetic variants in ALDH1B1 and alcohol dependence risk in a British and Irish population: A bioinformatic and genetic study

PLoS ONE ◽  
2017 ◽  
Vol 12 (6) ◽  
pp. e0177009 ◽  
Author(s):  
Michael J. Way ◽  
M. Adam Ali ◽  
Andrew McQuillin ◽  
Marsha Y. Morgan
Keyword(s):  
Alcohol Dependence ◽  
Genetic Study ◽  
Genetic Variants ◽  
Irish Population

scholarly journals Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis

2006 ◽  
Vol 15 (9) ◽  
pp. 1539-1549 ◽  
Author(s):  
Howard J. Edenberg ◽  
Xiaoling Xuei ◽  
Hui-Ju Chen ◽  
Huijun Tian ◽  
Leah Flury Wetherill ◽  
...  
Keyword(s):  
Alcohol Dehydrogenase ◽  
Alcohol Dependence ◽  
Comprehensive Analysis

Association of genetic variations in alcohol dehydrogenase 4 with alcohol dependence in Italian population sample

2008 ◽  
Vol 1 (1) ◽  
pp. 580-581
Author(s):  
Chiara Turchi ◽  
Loredana Buscemi ◽  
Francesco Piva ◽  
Federica Alessandrini ◽  
Valerio Onofri ◽  
...  
Keyword(s):  
Alcohol Dehydrogenase ◽  
Alcohol Dependence ◽  
Population Sample ◽  
Genetic Variations ◽  
Italian Population

scholarly journals Association study of the Ile349val polymorphism of the gene ADH1C and alcohol dependence

2011 ◽  
Vol 60 (1) ◽  
pp. 7-10 ◽  
Author(s):  
André Soares Rebello ◽  
Rodrigo Moura-Neto ◽  
Maria da Glória da Costa Carvalho
Keyword(s):  
Polymerase Chain Reaction ◽  
Alcohol Dehydrogenase ◽  
Alcohol Dependence ◽  
Alcoholics Anonymous ◽  
Control Group ◽  
Chain Reaction ◽  
Alcohol Dependence Syndrome ◽  
Genotype Difference ◽  
Polymerase Chain ◽  
Janeiro City

OBJECTIVE: The aim of this study was to investigate the polymorphism Ile349Val of the enzyme alcohol dehydrogenase ADH1C gene among individuals with alcohol dependence syndrome (ADS) attending Alcoholics Anonymous (AA) meetings. METHODS: A total of 120 subjects residing in Rio de Janeiro city participated in this study. Subjects were divided into two groups: a group consisting of 54 individuals from the ADS group and 66 individuals that declared not having any alcohol dependence (control group). DNA was extracted from mouth epithelial cells by phenol-chloroform method and further submitted to amplification by polymerase chain reaction (PCR). RESULTS: Our results did not show differences between the genotypes of control individuals and ADS subjects. Nevertheless, we found increased rates of alcoholism in families of ADS subjects as compared to controls. CONCLUSIONS: Our results did not show any genotype difference on the ADH1C gene when control and AA genotypes are compared.

Association between dopamine D2 receptor (DRD2) genetic variants and alcohol dependence in Han Chinese in Taiwan

2014 ◽  
Vol 220 (3) ◽  
pp. 1174-1175
Author(s):  
Pei-Chen Tsai ◽  
Chaio-Chicy Chen ◽  
Chun-Hung Pan ◽  
Wen-Chi Jan ◽  
Po-Hsiu Kuo ◽  
...  
Keyword(s):  
Alcohol Dependence ◽  
Genetic Variants ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Han Chinese ◽  
Dopamine D2

scholarly journals An Electrophoretically Cryptic Alcohol Dehydrogenase Variant in Drosophila Melanogaster. 11. Post-Electrophoresis Heat-Treatment Screening of Natural Populations

1980 ◽  
Vol 33 (5) ◽  
pp. 575 ◽  
Author(s):  
AV Wilks ◽  
JB Gibson ◽  
JG Oakeshott ◽  
GK Chambers
Keyword(s):  
Heat Treatment ◽  
Alcohol Dehydrogenase ◽  
Substrate Specificity ◽  
Electrophoretic Mobility ◽  
Genetic Variants ◽  
Partial Correlation ◽  
Natural Populations ◽  
Maximum Temperature ◽  
Common Genetic Variants ◽  
Temperature Variable

The two common genetic variants of alcohol dehydrogenase in D. melanogaster, ADH-F and ADH-S, differ in substrate specificity and electrophoretic mobility. A third inherited variant, ADH-FCh.D., has a substrate specificity like ADH-S, an electrophoretic mobility like ADH-F, but much greater thermostability than either of the others. ADH-FCh.D. can be identified after post-electrophoresis heat treatment (15 s at 43�C) on cellulose acetate sheets. The AdhFCh?D ? allele has been found in 19 of 34 natural populations in Australasia but its frequency in these populations does not exceed 0�06. The partial correlation between AdhFCh ?D ? frequency and a maximum temperature variable is significant and positive among the Australasian populations although different climatic associations are found for a thermostable form of ADH-F in North America.

Association of ADH4 genetic variants with alcohol dependence risk and related phenotypes: results from a larger multicenter association study

2011 ◽  
Vol 16 (2) ◽  
pp. 323-333 ◽  
Author(s):  
Ulrich W. Preuss ◽  
Monika Ridinger ◽  
Dan Rujescu ◽  
Jerzy Samochowiec ◽  
Christoph Fehr ◽  
...  
Keyword(s):  
Alcohol Dependence ◽  
Association Study ◽  
Genetic Variants

scholarly journals Variation in gastric alcohol dehydrogenase and the risk of alcohol dependence

2016 ◽  
Vol 3 ◽  
pp. 172-181
Author(s):  
Paulina Całka ◽  
Marzanna Ciesielka ◽  
Grzegorz Buszewicz ◽  
Grzegorz Teresiński
Keyword(s):  
Alcohol Dehydrogenase ◽  
Alcohol Dependence ◽  
Gastric Alcohol Dehydrogenase

Genetic Variants in the Fat Mass- and Obesity-Associated (FTO) Gene are Associated with Alcohol Dependence

2013 ◽  
Vol 51 (2) ◽  
pp. 416-424 ◽  
Author(s):  
Liang Wang ◽  
Xuefeng Liu ◽  
Xingguang Luo ◽  
Min Zeng ◽  
Lingjun Zuo ◽  
...  
Keyword(s):  
Alcohol Dependence ◽  
Fat Mass ◽  
Genetic Variants ◽  
Fto Gene
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