Regeneration of Maxillary Sinus Mucosa following Surgical Removal

A rapid regeneration of the epithelium takes place in the maxillary sinus in rabbits after experimental operative removal of the mucosa. Two weeks postoperatively the previously denuded areas have reepithelialized. The subepithelial glands, however, do not seem to regenerate. The normal sinus mucosa contains numerous serous glands in the lamina propria, but in the regenerated mucosa these glands are replaced by dense connective tissue. Atypical glands and polyp formations are sometimes encountered, but goblet cells are sparse. Furthermore, the sinus cavity on the operated side is reduced in size compared with the nonoperated side because of fibrosis and periosteal reactions including bone degradation and neogenesis. This study indicates that although the mucosa is reepithelialized within 2 weeks, the regeneration of the lamina propria is incomplete, and reactive cellular processes such as bone remodeling, fibroblast proliferation, and formation of polyps and “atypical glands” are characteristic of regenerating mucosa.

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Submucosal glands after maxillary sinus surgery. An experimental study in rabbits

The Journal of Laryngology & Otology ◽

10.1017/s0022215100134504 ◽

1996 ◽

Vol 110 (7) ◽

pp. 644-648 ◽

Cited By ~ 2

Author(s):

Pablo J. Melgarejo-Moreno ◽

Inmaculada Ribera-Cortada ◽

Diego Hellin-Meseguer

Keyword(s):

Electron Microscopy ◽

Maxillary Sinus ◽

Light And Electron Microscopy ◽

Complete Removal ◽

Sinus Surgery ◽

Secretory Cells ◽

Surgical Removal ◽

New Zealand White Rabbits ◽

And Control ◽

Sinus Mucosa

AbstractThirty New Zealand White rabbits underwent unilateral partial or complete removal of maxillary sinus mucosa in order to evaluate submucosal maxillary sinus glands. After three months, specimens were taken for examination from all operated on and control sinuses. Bacteriological cultures, light and electron microscopy were performed. Histopathological findings showed a decrease in the number of serous glands and significant inflammation was present in the sinus in which there was complete surgical removal. Electron microscopy revealed changes in the secretory cells of the serous glands in the regenerated postsurgical mucosa.

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Bacteriology of endoscopically normal maxillary sinuses

The Journal of Laryngology & Otology ◽

10.1017/s0022215100145311 ◽

1999 ◽

Vol 113 (9) ◽

pp. 825-828 ◽

Cited By ~ 27

Author(s):

Rong-San Jiang ◽

Kai-Li Liang ◽

Jinq-Wen Jang ◽

Chen-Yi Hsu

Keyword(s):

Maxillary Sinus ◽

Biopsy Forceps ◽

Paranasal Sinusitis ◽

Endoscopic Findings ◽

Sinus Cavity ◽

Sinus Ostium ◽

Aerobic And Anaerobic ◽

Sinus Mucosa ◽

Maxillary Sinuses

AbstractThe bacteriology of maxillary sinuses with normal endoscopic findings is reported in this study. When transantral sinoscopy was used to examine the maxillary sinuses, the whole maxillary sinus was inspected with different-angle endoscopes. If no lesion was seen over the whole maxillary sinus mucosa, no secretion existed in the maxillary sinus cavity, and the maxillary sinus ostium was wide open, the maxillary sinus was considered endoscopically normal. The bacteriology of these endoscopically normal maxillary sinuses was studied by passing cotton-tipped sticks through the cannula to collect swab specimens. In some cases, a biopsy forceps was also passed to obtain mucosal specimens. The specimens were sent to the laboratory for aerobic and anaerobic cultures. Between July 1990 and May 1998, 83 swab and 31 mucosal specimens were collected from 69 patients who had not taken any antibiotic within 10 days before endoscopy. The culture rates were 62.3 per cent (35/53) from swab specimens and 57.1 per cent (eight out of 14) from mucosal specimens in patients with the diagnosis of chronic paranasal sinusitis, and were 46.7 per cent (14/30) from swab specimens and 41. 2 per cent (seven out of 17) from mucosal specimens in patients without this diagnosis. This study shows that endoscopically normal maxillary sinuses are not sterile.

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Foreign Body Displacement For The Maxillary Sinus And Surgical Removal By The Caldwell-Luc Technique: Clinical Case

International Journal of Case Studies in Clinical Research ◽

10.25141/2472-102x-2017-4.0090 ◽

2017 ◽

Vol 1 (4) ◽

pp. 90-94

Author(s):

Marques FCC ◽

Keyword(s):

Foreign Body ◽

Maxillary Sinus ◽

Clinical Case ◽

Surgical Removal

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Immunohistochemical changes of maxillary sinus mucosa with underlying adenomatous polyposis

Pathologia ◽

10.14739/2310-1237.2017.1.97793 ◽

2017 ◽

Vol 0 (1) ◽

Author(s):

Yu. M. Andreychyn ◽

I. S. Kovalenko

Keyword(s):

Maxillary Sinus ◽

Adenomatous Polyposis ◽

Sinus Mucosa

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Morphofunctional State of the Maxillary Sinus Mucosa in Patients After Endoscopic Infundibulotomy

International Journal of Advanced Dental Sciences and Technology ◽

10.35940/ijadst.c1006.101321 ◽

2021 ◽

Vol 1 (3) ◽

pp. 6-10

Author(s):

Djuraev Jamolbek Abdukakharovich ◽

◽

Makhsitaliev Mukhammadbobur Ibrokhimovich, Ibrokhimovich ◽

Keyword(s):

Nasal Cavity ◽

Maxillary Sinus ◽

Chronic Rhinosinusitis ◽

Mucous Membrane ◽

Paranasal Sinuses ◽

Pathological Process ◽

Fundamental Factor ◽

Sinus Mucosa ◽

Morphological State

The work carried out made it possible to substantiate the need to apply a method for studying the frequency of beating of cilia of the mucous membrane of the nasal cavity and paranasal sinuses in patients with chronic rhinosinusitis when choosing treatment tactics in an ENT hospital. Analysis of the study of data on the functional and morphological state of the mucous membrane of the nasal cavity and maxillary sinus allows us to judge the severity of the pathological process before surgery, which is the fundamental factor in the algorithm for the treatment of chronic rhinosinusitis.

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A Sinus Floor Reaugmentation Technique Around an Apically Exposed Implant Into the Maxillary Sinus

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-18-00271 ◽

2019 ◽

Vol 45 (3) ◽

pp. 213-217

Author(s):

Daisuke Ueno ◽

Noriko Banba ◽

Akira Hasuike ◽

Kazuhiko Ueda ◽

Toshiro Kodama

Keyword(s):

Case Report ◽

Maxillary Sinus ◽

Dental Implants ◽

Treatment Option ◽

Prolonged Treatment ◽

Sinus Cavity ◽

Posterior Maxilla ◽

Sinus Floor Augmentation ◽

Sinus Floor ◽

Recovery Approach

Sinus floor augmentation (SFA) is the most predictable treatment option in the atrophic posterior maxilla. However, exposure of the apical implant body into the maxillary sinus cavity is an occasionally observed phenomenon after SFA. Although most penetrating dental implants remain completely asymptomatic, they may induce recurrent rhinosinusitis or implant loss. Removal of the implant should be considered if there is significant implant exposure that results in prolonged treatment and increased costs. This case report demonstrates a recovery approach using sinus floor reaugmentation without implant removal in a patient with an apically exposed implant into the maxillary sinus cavity.

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Goat Model for Direct Visualizing the Effectiveness of Detaching Sinus Mucosa in Real Time During Crestal Maxillary Sinus Floor Elevation

Journal of Oral Implantology ◽

10.1563/aaid-joi-d-16-00102 ◽

2017 ◽

Vol 43 (4) ◽

pp. 247-253

Author(s):

Jiadong Fan ◽

Pin Hu ◽

Yanfeng Li ◽

Fuli Wang ◽

Xinming Dong ◽

...

Keyword(s):

Maxillary Sinus ◽

Real Time ◽

Ex Vivo ◽

Sinus Lift ◽

Sinus Floor Elevation ◽

Maxillary Sinus Floor ◽

Sinus Floor ◽

Maxillary Sinus Floor Elevation ◽

Sinus Mucosa ◽

Space Volume

The procedure of crestal maxillary sinus floor elevation presents a great challenge to the field of implant dentistry. Due to the limited visualization in this procedure, the effectiveness of detaching sinus mucosa could not be assessed in real time. We recently developed an ex vivo goat sinus model by cutting the goat residual skulls along four lines determined from computerized tomography (CT) scans, extracting the maxillary premolar or molar teeth, and preparing implant socket in the maxilla. The generated ex vivo goat sinus models exposed the maxilla and the whole maxillary sinus mucosa, thus enabling real-time observation of detaching maxillary sinus mucosa via directly visualizing the working situation of sinus lift tool in the models and directly measuring the length of detached mucosa and space volume generated under the elevated sinus mucosa. One commercially available umbrella-shaped sinus lift curette was used to detach the maxillary sinus mucosa to evaluate the effectiveness of the ex vivo goat sinus models. The results showed that this curette could detach the sinus mucosa 3.75 mm in length in the mesiodistal direction and 2.81 mm in the buccal-palatal direction. Moreover, a space volume of 52.7 μl could be created under the elevated sinus mucosa in the goat ex vivo models. All the experimental results suggested that this ex vivo goat sinus model might be useful in the evaluation of improved or newly designed sinus lift tools for elevating the maxillary sinus mucosa via the crestal approach.

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