Death Anxiety and Related Factors in Schizophrenia Patients: Controlled Study

2021 ◽  
pp. 003022282110331
Author(s):  
Seher Serez Öztürk ◽  
İsmet Esra Çiçek ◽  
İbrahim Eren
Keyword(s):  
Death Anxiety ◽  
Psychosocial Interventions ◽  
Anxiety Level ◽  
Controlled Study ◽  
Psychotic Symptoms ◽  
Healthy Controls ◽  
Obsessive Compulsive ◽  
Related Factors ◽  
Obsessive Compulsive Symptoms ◽  
Clinical Variables

The aim of the study was to investigate the level of death anxiety and related sociodemographic and clinical variables in schizophrenia patients. One hundred and ninety schizophrenia patients and 110 healthy controls were included the study. Death anxiety measured with Templer Death Anxiety Scale (TDAS). The patients were also evaluated with scales in terms of depression, anxiety, obsessive-compulsive symptoms, and suicide. The death anxiety level in patients with schizophrenia was significantly higher than the healthy controls. The severity of depressive and psychotic symptoms were related to the level of death anxiety. Patients with schizophrenia may need more protection and psychosocial interventions about death related themes.

scholarly journals Evidence for a Shared Etiological Mechanism of Psychotic Symptoms and Obsessive-Compulsive Symptoms in Patients with Psychotic Disorders and Their Siblings

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0125103 ◽  
Author(s):  
Marije Swets ◽  
Frank Van Dael ◽  
Sabine Roza ◽  
Robert Schoevers ◽  
Inez Myin-Germeys ◽  
...  
Keyword(s):  
Psychotic Disorders ◽  
Psychotic Symptoms ◽  
Obsessive Compulsive ◽  
Obsessive Compulsive Symptoms

scholarly journals Differences between individuals with schizophrenia or obsessive-compulsive disorder and healthy controls in social cognition and mindfulness skills: A controlled study

PLoS ONE ◽  
2019 ◽  
Vol 14 (12) ◽  
pp. e0225608
Author(s):  
Yolanda López-del-Hoyo ◽  
Manuel González Panzano ◽  
Guillermo Lahera ◽  
Paola Herrera-Mercadal ◽  
Mayte Navarro-Gil ◽  
...  
Keyword(s):  
Social Cognition ◽  
Obsessive Compulsive Disorder ◽  
Controlled Study ◽  
Healthy Controls ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Mindfulness Skills

Plasma prolactin response to d-fenfluramine is blunted in bulimic patients with frequent binge episodes

1998 ◽  
Vol 28 (4) ◽  
pp. 975-983 ◽  
Author(s):  
P. MONTELEONE ◽  
F. BRAMBILLA ◽  
F. BORTOLOTTI ◽  
C. FERRARO ◽  
M. MAJ
Keyword(s):  
Plasma Levels ◽  
Rating Scales ◽  
Low Frequency ◽  
Significant Negative Correlation ◽  
Plasma Prolactin ◽  
Healthy Controls ◽  
Obsessive Compulsive ◽  
Double Blind ◽  
Obsessive Compulsive Symptoms ◽  
Plasma Prl

Background. Abnormalities of brain serotonin (5-HT) transmission have been implicated in the pathophysiology of bulimia nervosa (BN), but no conclusive data have yet been provided. The purpose of this study was to assess 5-HT transmission via the measurement of the prolactin (PRL) response to the specific 5-HT releasing agent d-fenfluramine (d-FEN) in both patients with BN and comparison subjects.Methods. According to a double-blind placebo-controlled design, plasma PRL response to d-FEN was measured in 14 drug-free bulimics and 14 matched healthy controls. In both patients and controls, eating-related psychopathology, depressive and obsessive–compulsive symptoms, and aggressiveness were measured by rating scales.Results. Baseline plasma levels of PRL and 17β-oestradiol were significantly reduced in bulimic patients, whereas basal plasma levels of cortisol did not significantly differ from healthy controls. PRL response to d-FEN was not different between patients and controls as groups, but it was significantly blunted in bulimics with high frequency bingeing ([ges ]2 binge episodes per day; N=7) as compared to both those with low frequency bingeing ([les ]1 binge episode per day; N=7) and matched controls. A significant negative correlation emerged between the frequency of binge episodes and the hormone response to d-FEN. Moreover, although patients scored higher than healthy subjects on rating scales assessing depressive and obsessive–compulsive symptoms and aggressiveness, no significant correlation was found between these measures and the PRL response to d-FEN.Conclusions. These results support the idea that serotonin transmission is impaired in bulimic patients with frequent binge episodes.

scholarly journals Mediating Role of Rumination and Negative Affect in the Effect of Mind-Wandering on Symptoms in Patients With Obsessive-Compulsive Disorder

2021 ◽  
Vol 12 ◽  
Author(s):  
Pengchong Wang ◽  
Wenwen Cao ◽  
Tao Chen ◽  
Jian Gao ◽  
Yifan Liu ◽  
...  
Keyword(s):  
Negative Affect ◽  
Obsessive Compulsive Disorder ◽  
Mind Wandering ◽  
Healthy Controls ◽  
Response Scale ◽  
Obsessive Compulsive ◽  
Obsessive Compulsive Symptoms ◽  
Compulsive Disorder ◽  
Mediating Role ◽  
The Relationship

To explore the relationship between negative affect, mind-wandering, rumination and obsessive-compulsive symptoms, 100 patients with obsessive-compulsive disorder and 100 healthy controls were assessed using the Obsessive-Compulsive Inventory, the Beck Anxiety Inventory, the Beck Depression Inventory, the Mind Wandering Scale and the Ruminative Response Scale. The results show that (i) patients diagnosed with obsessive-compulsive disorder displayed higher obsessive-compulsive symptoms, negative affect, mind-wandering and rumination compared with healthy controls; (ii) negative affect, mind-wandering and rumination were positively correlated with the severity of obsessive-compulsive symptoms; (iii) mind-wandering predicted the severity of obsessive-compulsive symptoms (both directly and indirectly); (iv) rumination and negative affect mediated the relationship between mind-wandering and obsessive-compulsive symptoms. The results preliminarily reveal the relationship between mind-wandering and psychopathological obsessive-compulsive symptoms, providing a reference for exploring novel psychological treatments for obsessive-compulsive disorder.

A Pilot Controlled Study of Fluoxetine for Obsessive-Compulsive Symptoms in Children with Touretteʼs Syndrome

1993 ◽  
Vol 16 (2) ◽  
pp. 167-172 ◽  
Author(s):  
R. Kurlan ◽  
P. G. Como ◽  
C. Deeley ◽  
M. McDermott ◽  
M. P. McDermott
Keyword(s):  
Controlled Study ◽  
Obsessive Compulsive ◽  
Obsessive Compulsive Symptoms

Platelet serotonin decrease in panic disorder with obsessive compulsive symptoms

1992 ◽  
Vol 7 (1) ◽  
pp. 27-31
Author(s):  
D Servant ◽  
D Bailly ◽  
C Perret ◽  
J Vignau ◽  
PJ Parquet
Keyword(s):  
Panic Disorder ◽  
Healthy Controls ◽  
Obsessive Compulsive ◽  
Obsessive Compulsive Symptoms ◽  
Platelet Serotonin ◽  
Serotonergic Dysfunction

SummaryPlatelet 5-HT levels were determined by fluorescent orthophthaldehyde assay in 33 panic disorder patients with and without obsessive compulsive symptoms (PD + OCS: n = 16; PD-OCS: n = 17) according to DSM III-R criteria, and compared With those of 38 healthy controls. Mean platelet levels were significantly lower in PD + OCS than in PD-OCS patients. The results are discussed in relation to serotonergic dysfunction linked to PD and OCS comorbidity.

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