Plasmodium vivax malaria presenting as acute respiratory distress syndrome: a case report

2013 ◽  
Vol 43 (2) ◽  
pp. 83-85 ◽  
Author(s):  
Ahmad Kashfi Ab Rahman ◽  
Farah Nadiah Sulaiman
2020 ◽  
Vol 7 (43) ◽  
pp. 2470-2473
Author(s):  
Geetha Priyadarsini Kamminana ◽  
Jyotirmayi Boddu ◽  
Vasudev Rajapantula

BACKGROUND Among malarial parasites, Plasmodium vivax is most prevalent in humans. Recent studies have shown severe and fatal complications with Plasmodium vivax infection. We wanted to evaluate the clinical spectrum, complications and outcomes of adult subjects with Plasmodium vivax malaria mono-infection. METHODS This is a retrospective study involving 100 subjects RESULTS Males were more commonly affected. It was most prevalent in the second decade of life. Fever was present in all patients. The other common symptoms were headache, vomiting, and jaundice. The incidence of associated clinical findings were pallor (43 %), icterus (21%), hepatomegaly (39 %) and splenomegaly (27 %). Severe thrombocytopenia was seen in 18 %, hyper bilirubinaemia in 39 % of subjects. Cerebral malaria was observed in 3 %, acute kidney injury in 13 %, ARDS (Acute Respiratory Distress Syndrome) in 5 % cases, MODS (Multi Organ Dysfunction Syndrome) was seen in 3 % cases, with a mortality of 3 %. CONCLUSIONS Complications like ARDS, AKI (Acute Kidney Injury), cerebral malaria and MODS were observed in benign tertian malaria subjects in our study. Cerebral malaria, AKI, MODS, ARDS were associated with high degrees of mortality. KEYWORDS Plasmodium vivax, ARDS (Acute Respiratory Distress Syndrome), Cerebral Malaria, AKI (Acute Kidney Injury), MODS (Multiorgan Dysfunction Syndrome)


Author(s):  
Atiullah Malik ◽  
Yadav Ponvijaya ◽  
Kshithija Sajjan ◽  
Chirag Gurbani

Acute respiratory distress syndrome (ARDS) is a life threatening complication of many infectious diseases like malaria, H1N1, bacterial pneumonia, and leptospira. Malaria is an important treatable cause of ARDS. ARDS can develop either at initial presentation or after initiation of treatment when the parasitaemia is falling and patient is improving. 58 year old female presented with high grade fever and breathlessness since 5 days. Arterial blood gas (ABG) on admission showed type 1 respiratory failure and chest X-ray was suggestive of ARDS. Thus patient was shifted to intensive care unit and was put on non-invasive ventilation. PBS was positive for Plasmodium vivax malaria and patient was started on antimalarial drugs. Considering the epidemic of H1N1 swab was sent for polymerase chain reaction (PCR) which turned out to be negative. Thus antimalarial and supportive treatment for ARDS was continued. Patient was discharged on day 11 and started on tablet primaquine to prevent relapse. ARDS is a hard to predict late complication of severe malaria. ARDS in malaria is a disease with high mortality. Early diagnosis and institution of specific antimalarial treatment along with assisted ventilation can be life-saving.


Author(s):  
André V. Lomar ◽  
José E. Vidal ◽  
Frederico P. Lomar ◽  
Carmen Valente Barbas ◽  
Gustavo Janot de Matos ◽  
...  

2015 ◽  
Vol 9 (08) ◽  
pp. 910-913 ◽  
Author(s):  
Himanshu Gupta ◽  
Mohammed P Afsal ◽  
Seema M Shetty ◽  
Kapaettu Satyamoorthy ◽  
Shashikiran Umakanth

Plasmodium falciparum (Pf) is associated with numerous complications and high mortality, whereas Plasmodium vivax (Pv) infection is generally considered to be benign. However, severe complications, such as acute respiratory distress syndrome (ARDS) in Pv infection, are emerging. This case report highlights the complication of ARDS during the course of Pv infection in a 60-year-old woman. The diagnosis of the patient was made using microscopy, immunochromatography, and polymerase chain reaction assays for Pf and Pv species. The data indicated the presence of mono-Pv infection in the patient’s blood, and Pf infection was specifically ruled out. The patient was discharged after intensive supportive care and antimalarial treatment. Pv infection is associated with ARDS and other complications such as sepsis and multi-organ dysfunction syndrome; this enhanced severity of Pv infection, if unrecognized, can lead to more deaths in malaria-endemic areas.


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