Young and Elderly Type 2 Diabetic Patients Inhaling Insulin with the AERx® Insulin Diabetes Management System: A Pharmacokinetic and Pharmacodynamic Comparison

2003 ◽  
Vol 43 (11) ◽  
pp. 1228-1234 ◽  
Author(s):  
Robert R. Henry ◽  
Sunder Mudaliar ◽  
Neelima Chu ◽  
Dennis Kim ◽  
Debra Armstrong ◽  
...  
Keyword(s):  
Management System ◽  
Diabetes Management ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
System A ◽  
Type 2 Diabetic

scholarly journals Barriers to Diet and Exercise among Nepalese Type 2 Diabetic Patients

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Saruna Ghimire
Keyword(s):  
Diabetes Management ◽  
Social Acceptability ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Cross Sectional ◽  
Exercise Timing ◽  
Diet And Exercise ◽  
Type 2 Diabetic

This study aims to identify the modifiable barriers encountered by type 2 diabetic patients in Nepal to achieving their recommended dietary and exercise advice. A cross-sectional study was conducted among 197 type 2 diabetic patients, attending a diabetic clinic. Binary logistic regression models were used to identify perceived barriers. About 41% and 46% of the participants were noncompliant to diet and exercise advice, respectively; only 35.5% the participants were compliant to both. Perceived social acceptability (OR = 0.14; 95% CI: 0.03–0.58) and reminder to action (OR = 2.77; 95% CI: 1.38–5.53) were associated with noncompliance to diet. Most of the barriers to diet were related to taste, feast and festivals, lack of knowledge, and availability of healthy options. Self-efficacy (OR = 0.09; 95% CI: 0.02–0.34) and social acceptability (OR = 0.12; 95% CI: 0.04–0.34) were significant predictors of noncompliance to exercise. The supportive role of children and spouse and the opposing role of friends and relatives were important for compliance to both. A misconception on diabetes severity, effectiveness of healthy lifestyle, and exercise timing was prevalent among the study participants. Addressing the modifiable barriers identified in this study is essential for successful diabetes management in Nepal.

scholarly journals The New Era for Reno-Cardiovascular Treatment in Type 2 Diabetes

2019 ◽  
Vol 8 (6) ◽  
pp. 864 ◽  
Author(s):  
Clara García-Carro ◽  
Ander Vergara ◽  
Irene Agraz ◽  
Conxita Jacobs-Cachá ◽  
Eugenia Espinel ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Kidney Disease ◽  
Diabetes Management ◽  
Angiotensin Receptor Blockers ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Converting Enzyme Inhibitors ◽  
Dipeptidyl Peptidase 4 Inhibitors ◽  
Type 2 Diabetic

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease in the developed world. Until 2016, the only treatment that was clearly demonstrated to delay the DKD was the renin-angiotensin system blockade, either by angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. However, this strategy only partially covered the DKD progression. Thus, new strategies for reno-cardiovascular protection in type 2 diabetic patients are urgently needed. In the last few years, hypoglycaemic drugs, such as sodium-glucose co-transporter 2 inhibitors and glucagon-like peptide-1 receptor agonists, demonstrated a cardioprotective effect, mainly in terms of decreasing hospitalization for heart failure and cardiovascular death in type 2 diabetic patients. In addition, these drugs also demonstrated a clear renoprotective effect by delaying DKD progression and decreasing albuminuria. Another hypoglycaemic drug class, dipeptidyl peptidase 4 inhibitors, has been approved for its use in patients with advanced chronic kidney disease, avoiding, in part, the need for insulinization in this group of DKD patients. Studies in diabetic and non-diabetic experimental models suggest that these drugs may exert their reno-cardiovascular protective effect by glucose and non-glucose dependent mechanisms. This review focuses on newly demonstrated strategies that have shown reno-cardiovascular benefits in type 2 diabetes and that may change diabetes management algorithms.

scholarly journals FOOD AND LIVING HABITS OF DIABETIC PATIENTS TYPE 2 MONITORED TO DEPARTMENTAL HOSPITAL CENTER (CHD) ATACORA (BENIN).

2019 ◽  
Vol 8 (4) ◽  
Author(s):  
Christian Tétédé Rodrigue Konfo
Keyword(s):  
Food Habits ◽  
Diabetes Management ◽  
Diabetes Type 2 ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Cross Sectional ◽  
Rapid Urbanization ◽  
Validated Questionnaire ◽  
Type 2 Diabetic

Rapid urbanization and the globalization of the food market have led to changes in nutritional behavior and the way of life of populations, including developing countries such as Benin, with the consequent emergence of various pathologies such as diabetes type 2. The aim of this study was to study the food profile and lifestyle of type 2 diabetic patients followed by CHD-Atacora from Natitingou, Benin.It was a cross-sectional study with a descriptive and analytical purpose. Sociodemographic, biometric and dietary information were collected on the basis of a pre-established and validated questionnaire. A total of 204 type 2 diabetic patients were enrolled in the study. The mean age of the subjects was 56 ± 12 years with female predominance (sex-ratio = 1.5). The Wama, Bariba and Ditamari ethnic groups accounted for 43% of the sample. Almost 75% have a level of education less than or equal to secondary school. The main comorbidities were abdominal obesity (90%) and high blood pressure (48%). About 70% of the subjects reported that they regularly engage in physical activity, including walking (60%). Cereal-based foods (maize, rice, millet and sorghum) and vegetable sauces largely dominate the food consumed by the subjects (90%). Food habits including cereal-based foods, mainly maize seem to have a definite impact on the management of the disease. Educational attainment would also be a key factor to consider as higher educated individuals appear to be more aware of the influence of food habits and lifestyle on diabetes management.  

scholarly journals Impact of Diabetes Management on Diabetes Control and Resource Consumption in Type 2 Diabetic Patients

2016 ◽  
Vol 19 (7) ◽  
pp. A683
Author(s):  
JC Chan ◽  
A Ramachandran ◽  
JC Mbanya ◽  
MV Shestakova ◽  
JJ Gagliardino ◽  
...  
Keyword(s):  
Diabetes Management ◽  
Resource Consumption ◽  
Diabetes Control ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Vitamin D3 supplementation improves glycemic control in type 2 diabetic patients: Results from an Italian clinical trial

2020 ◽  
pp. 1-10
Author(s):  
Giuseppe Derosa ◽  
Angela D’Angelo ◽  
Chiara Martinotti ◽  
Maria Chiara Valentino ◽  
Sergio Di Matteo ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Metabolic Control ◽  
Vitamin D3 ◽  
Therapy Group ◽  
Hypoglycemic Agents ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Abstract. Background: to evaluate the effects of Vitamin D3 on glyco-metabolic control in type 2 diabetic patients with Vitamin D deficiency. Methods: one hundred and seventeen patients were randomized to placebo and 122 patients to Vitamin D3. We evaluated anthropometric parameters, glyco-metabolic control, and parathormone (PTH) value at baseline, after 3, and 6 months. Results: a significant reduction of fasting, and post-prandial glucose was recorded in Vitamin D3 group after 6 months. A significant HbA1c decrease was observed in Vitamin D3 (from 7.6% or 60 mmol/mol to 7.1% or 54 mmol) at 6 months compared to baseline, and to placebo (p < 0.05 for both). At the end of the study period, we noticed a change in the amount in doses of oral or subcutaneous hypoglycemic agents and insulin, respectively. The use of metformin, acarbose, and pioglitazone was significantly lower (p = 0.037, p = 0.048, and p = 0.042, respectively) than at the beginning of the study in the Vitamin D3 therapy group. The units of Lispro, Aspart, and Glargine insulin were lower in the Vitamin D3 group at the end of the study (p = 0.031, p = 0.037, and p = 0.035, respectively) than in the placebo group. Conclusions: in type 2 diabetic patients with Vitamin D deficiency, the restoration of value in the Vitamin D standard has led not only to an improvement in the glyco-metabolic compensation, but also to a reduced posology of some oral hypoglycemic agents and some types of insulin used.

Evaluation of aortic arch calcification in type 2 diabetic patients

VASA ◽  
2005 ◽  
Vol 34 (2) ◽  
pp. 113-117 ◽  
Author(s):  
Papanas ◽  
Symeonidis ◽  
Maltezos ◽  
Giannakis ◽  
Mavridis ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Aortic Arch ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Insulin Dependence ◽  
Artery Disease ◽  
Type 2 Diabetic ◽  
Aortic Arch Calcification

Background: The purpose of this study is to evaluate the severity of aortic arch calcification among type 2 diabetic patients in association with diabetes duration, diabetic complications, coronary artery disease and presence of cardiovascular risk factors. Patients and methods: This study included 207 type 2 diabetic patients (101 men) with a mean age of 61.5 ± 8.1 years and a mean diabetes duration of 13.9 ± 6.4 years. Aortic arch calcification was assessed by means of posteroanterior chest X-rays. Severity of calcification was graded as follows: grade 0 (no visible calcification), grade 1 (small spots of calcification or single thin calcification of the aortic knob), grade 2 (one or more areas of thick calcification), grade 3 (circular calcification of the aortic knob). Results: Severity of calcification was grade 0 in 84 patients (40.58%), grade 1 in 64 patients (30.92%), grade 2 in 43 patients (20.77%) and grade 3 in 16 patients (7.73%). In simple regression analysis severity of aortic arch calcification was associated with age (p = 0.032), duration of diabetes (p = 0.026), insulin dependence (p = 0.042) and presence of coronary artery disease (p = 0.039), hypertension (p = 0.019), dyslipidaemia (p = 0.029), retinopathy (p = 0.012) and microalbuminuria (p = 0.01). In multiple regression analysis severity of aortic arch calcification was associated with age (p = 0.04), duration of diabetes (p = 0.032) and presence of hypertension (p = 0.024), dyslipidaemia (p = 0.031) and coronary artery disease (p = 0.04), while the association with retinopathy, microalbuminuria and insulin dependence was no longer significant. Conclusions: Severity of aortic arch calcification is associated with age, diabetes duration, diabetic complications (retinopathy, microalbuminuria), coronary artery disease, insulin dependence, and presence of hypertension and dyslipidaemia.

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