scholarly journals Middle Turbinate Seromucinous Hamartoma in a Patient With Primary Atrophic Rhinitis

2020 ◽  
pp. 014556132093584
Author(s):  
Aleksandar Perić ◽  
Ljiljana Jovančević ◽  
Biserka Vukomanović Đurđević
2010 ◽  
Vol 48 (4) ◽  
pp. 394-400
Author(s):  
X.B. Chen ◽  
S.C. Leong ◽  
H.P. Lee ◽  
V.F.H. Chong ◽  
D.Y. Wang

BACKGROUND: Turbinate reduction surgery may be indicated for inferior turbinate enlargement when conservative treatment fails. The aim of this study was to evaluate the effects of inferior turbinate surgery on nasal aerodynamics using computational fluid dynamics (CFD) simulations. METHODS: CFD simulations were performed for the normal nose, enlarged inferior turbinate and following three surgical procedures: (1) resection of the lower third free edge of the inferior turbinate, (2) excision of the head of the inferior turbinate and (3) radical inferior turbinate resection. The models were constructed from MRI scans of a healthy human subject and a turbulent flow model was used for the numerical simulation. The consequences of the three turbinate surgeries were compared with originally healthy nasal model as well as the one with severe nasal obstruction. RESULTS: In the normal nose, the bulk of streamlines traversed the common meatus adjacent to the inferior and middle turbinate in a relatively vortex free flow. When the inferior turbinate was enlarged, the streamlines were directed superiorly at higher velocity and increased wall shear stress in the nasopharynx. Of the three surgical techniques simulated, wall shear stress and intranasal pressures achieved near-normal levels after resection of the lower third. In addition, airflow streamlines and turbulence improved although it did not return to normal conditions. As expected, radical turbinate resection resulted in intra-nasal aerodynamics of atrophic rhinitis demonstrated in previous CFD studies. CONCLUSION: There is little evidence that inspired air is appropriately conditioned following radical turbinate surgery. Partial reduction of the hypertropic turbinate results in improved nasal aerodynamics, which was most evident following resection of the lower third. The results were based on a single individual and cannot be generalised without similar studies in other subjects.


Head & Neck ◽  
2014 ◽  
Vol 37 (2) ◽  
pp. E15-E18 ◽  
Author(s):  
Chien-Chia Huang ◽  
Ta-Jen Lee ◽  
Chi-Che Huang ◽  
Pei-Wen Wu

ORL ◽  
2021 ◽  
pp. 1-3
Author(s):  
David A. Rengifo ◽  
Varun V. Varadarajan ◽  
Jinping Lai ◽  
Jeb M. Justice

<b><i>Objectives:</i></b> Sinonasal hamartomas are benign neoplasms composed of disorganized mature tissue elements. Epithelial variants include respiratory epithelial adenomatoid hamartoma (REAH) and seromucinous hamartoma (SMH). Malignant transformation of REAH is rarely reported; however, the malignant transformation of SMH to adenocarcinoma has not been described. We report the first case of a transformation from SMH to adenocarcinoma. <b><i>Methods:</i></b> The medical records of a patient presenting with sinonasal SMH with malignant transformation to adenocarcinoma were reviewed. The NCBI database was queried for the literature regarding SMH and malignant transformation of sinonasal hamartomas. <b><i>Results:</i></b> A 39-year-old man presented with a left nasal mass, nasal obstruction, and epistaxis. Computed tomography and magnetic resonance imaging demonstrated a nonaggressive and heterogeneous left nasal mass with involvement of the middle turbinate and posterior ethmoid sinuses. He underwent endoscopic sinus surgery with complete excision of the mass. Pathology revealed SMH with focal areas of transition to low-grade adenocarcinoma characterized by stromal invasion but no bony, perineural, or lymphovascular invasion. Adjuvant treatment was not recommended. Literature review revealed no reported cases of malignant transformation of SMH. <b><i>Conclusion:</i></b> We report the first case of malignant transformation of SMH. Patients with SMH must be counseled that there is an extremely rare and potentially unrecognized risk of malignancy that may influence treatment and postoperative monitoring.


Author(s):  
A. W. Fetter ◽  
C. C. Capen

Atrophic rhinitis in swine is a disease of uncertain etiology in which infectious agents, hereditary predisposition, and metabolic disturbances have been reported to be of primary etiologic importance. It shares many similarities, both clinically and pathologically, with ozena in man. The disease is characterized by deformity and reduction in volume of the nasal turbinates. The fundamental cause for the localized lesion of bone in the nasal turbinates has not been established. Reduced osteogenesis, increased resorption related to inflammation of the nasal mucous membrane, and excessive resorption due to osteocytic osteolysis stimulated by hyperparathyroidism have been suggested as possible pathogenetic mechanisms.The objectives of this investigation were to evaluate ultrastructurally bone cells in the nasal turbinates of pigs with experimentally induced atrophic rhinitis, and to compare these findings to those in control pigs of the same age and pigs with the naturally occurring disease, in order to define the fundamental lesion responsible for the progressive reduction in volume of the osseous core.


Skull Base ◽  
2008 ◽  
Vol 18 (S 01) ◽  
Author(s):  
Seth Brown ◽  
Abtin Tabaee ◽  
Vijay Anand ◽  
Ameet Singh ◽  
Theodore Schwartz

1961 ◽  
Vol 20 (1) ◽  
pp. 88-92 ◽  
Author(s):  
W. G. Pond ◽  
S. J. Roberts ◽  
J. A. Dunn ◽  
J. M. King ◽  
J. H. Maner ◽  
...  
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