Three Cases of Parotid Hemangiomas in Adults

Hemangiomas account for only 0.4% to 0.6% of all parotid tumors, making them extremely rare in adults. Unlike pediatric parotid hemangiomas, those in adults typically present as asymptomatic swellings of the parotid, have no skin discoloration, and usually do not regress spontaneously. Therefore, an accurate diagnosis of parotid hemangiomas in adults before surgical excision is generally challenging. Herein, we present 3 cases of adult parotid hemangiomas. The patients all received parotidectomies with tumor resection. Histopathological analysis of the resected specimens revealed numerous dilated, thin- or thick-walled (small, large, or variably sized) vessels lined with flattened endothelial cells. A diagnosis of cavernous hemangioma of the parotid gland was established only after the histopathological analysis. Parotid cavernous hemangiomas in adults are rare and often misdiagnosed before surgical resection. Clinical presentation and imaging features on ultrasonography, computed tomography, magnetic resonance imaging, and angiography may support an accurate preoperative diagnosis. Surgical resection proved a suitable treatment approach for our 3 cases.

Download Full-text

Pediatric Extramedullary Epidural Spinal Teratomas: A Case Report and Review of the Literature

Case Reports in Orthopedics ◽

10.1155/2021/6702972 ◽

2021 ◽

Vol 2021 ◽

pp. 1-8

Author(s):

David G. Deckey ◽

Andrea Fernandez ◽

Nina J. Lara ◽

Steve Taylor ◽

Jamal McClendon ◽

...

Keyword(s):

Surgical Resection ◽

Motor Development ◽

Clinical Presentation ◽

Pediatric Population ◽

Mature Teratoma ◽

Cord Compression ◽

Histopathological Analysis ◽

Paravertebral Space ◽

Thoracic Spinal ◽

The Right

Background. Teratomas in the pediatric population are most commonly found in the sacrococcygeal region. Pediatric intraspinal teratomas, however, are an exceedingly rare central nervous system (CNS) neoplasm. The clinical presentation of these intraspinal neoplasms can vary significantly and thus can be difficult to identify in infants less than one year of age where verbal expression and motor development are still lacking. Case Description. A 7-month-old, previously healthy male presented with a thoracic scoliosis and an asymptomatic right midupper thoracic spinal prominence present since birth. MRI revealed an extensive heterogenous mass in the right epidural space from T5-T6 and the right paravertebral space, resulting in severe spinal stenosis. Outcome. Complete resection of the tumor, including a three-level neurotomy, was achieved by posterior decompression/laminectomy. The final tumor was consistent with a mature teratoma. The surgical resection was performed without any immediate complications. Conclusions. Extramedullary epidural teratomas are exceptionally rare tumors in the pediatric population. Clinical presentation can be ambiguous, particularly in an infant. MRI was useful in suggesting a teratoma as a potential diagnosis and for postoperative surveillance for recurrence. However, histopathological analysis remains the gold standard for definitive diagnosis. Surgical resection is the mainstay of treatment, especially in the setting of cord compression and progressive loss of motor function. Close follow-up is crucial to monitor for progressive spinal deformity or recurrence.

Download Full-text

A rare tumor of external auditory canal originated from ceruminous glands: A case raport

Polski Przegląd Otorynolaryngologiczny ◽

10.5604/01.3001.0012.1468 ◽

2018 ◽

Vol 7 (1) ◽

pp. 1-5

Author(s):

Katarzyna Amernik ◽

Aleksandra Kłodawska ◽

Ewa Jaworowska

Keyword(s):

Surgical Resection ◽

External Auditory Canal ◽

Tumor Resection ◽

Surgical Excision ◽

Histopathological Diagnosis ◽

Complete Excision ◽

Neck Tumors ◽

Subtotal Petrosectomy ◽

One Year ◽

Specific Symptoms

The external auditory canal neoplasms comprise less than 1 percent of all head and neck tumors. 2,4 percent of them originate from ceruminous glands. In the past all these tumours were called ceruminomas. In 1972 Wetli et al. classiffed these neoplasms into four groups: ceruminous adenomas, ceruminous carcinoma, adenoid cystic carcinomas and pleomorphic adenomas. Ceruminous adenocarcinoma is very rare. It has no specific symptoms, so an appropriate, quick diagnosis is difficult. It is very agressive. The treatment should be based on tumor resection and radiotherapy afterwards. We presented a case of 56 years old female with a mass in external ear canal, who underwent diagnostic surgical excision of external auditor canal tumour. The postoperative histopathological diagnosis was ceruminous adenocarcinoma (complete excision) and the patient received radiation therapy. Control CT and MR - performed one year after the surgery - showed possible local recurrence of pathology. The patient undergo maximal surgical resection with subtotal petrosectomy but in the postoperative histological examination there was no malignant cells. Treatment of neoplasms of external auditory canal should be based on radical surgical resection. Imaging diagnostic is very important in follow up but it can have limited value in term of its specifity.

Download Full-text

The “Endothelialized Muscularis Mucosae”: A Case Report Describing a Large Cavernous Hemangioma at the Terminal Ileum and a New Histologic Clue for Preoperative Diagnosis from Endoscopic Biopsy

Case Reports in Gastrointestinal Medicine ◽

10.1155/2015/454836 ◽

2015 ◽

Vol 2015 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Erin K. Purdy-Payne ◽

Jean F. Miner ◽

Brandon Foles ◽

Tien-Anh N. Tran

Keyword(s):

Surgical Resection ◽

Cavernous Hemangioma ◽

Terminal Ileum ◽

Preoperative Diagnosis ◽

Endoscopic Biopsy ◽

Imaging Features ◽

Patient Counseling ◽

Muscularis Mucosae ◽

Endoscopic Biopsies ◽

Cavernous Hemangiomas

Cavernous hemangiomas of the gastrointestinal tract are quite rare and, until now, have been difficult to diagnose preoperatively due their nonspecific presentations and imaging features, as well as a lack of histologic description pertaining to small superficial biopsies such as those obtained endoscopically. We report a unique case of a 4 cm transmural cavernous hemangioma in the terminal ileum with literature review and describe a new histologic finding—the “endothelialized muscularis mucosae,” which was discovered upon review of the endoscopic biopsy and could potentially facilitate preoperative diagnosis of these lesions from endoscopic biopsies in the future. These lesions have classically required surgical resection in order to make a definitive diagnosis and rule out malignancy, with which they share many historical and radiographic features. Due to their potential to cause bowel obstruction, intussusception, perforation, and hemorrhage, these lesions may ultimately require surgical resection to relieve symptoms or prevent or treat complications—however, surgical planning and patient counseling could be greatly improved by a preoperative diagnosis. Therefore, gastroenterologists, pathologists, and surgeons should be aware of the “endothelialized muscularis mucosae” which can be very helpful in diagnosing GI cavernous hemangiomas from endoscopic biopsies.

Download Full-text

Vagus Nerve Schwannoma At Cerebellopontine Angle With Extracranial Extension Through Jugular Foramen

10.21203/rs.3.rs-763030/v1 ◽

2021 ◽

Author(s):

Hao Tang ◽

Zhenghui Sun ◽

Jiashu Zhang ◽

Xinguang Yu

Keyword(s):

Vagus Nerve ◽

Brain Stem ◽

Surgical Resection ◽

Cerebellopontine Angle ◽

Parapharyngeal Space ◽

Tumor Resection ◽

Surgical Excision ◽

Jugular Foramen ◽

First Choice ◽

The Brain

Abstract Communicating tumors between the posterior fossa and parapharyngeal space are rare and difficult to diagnose and treat. Surgical excision of these space lesions is challenging because of the anatomical complexity of the area. In this case we successfully made full resection of a big rare vagus nerve schwannoma at cerebellopontine angle and parapharyngeal space. Surgical resection is the treatment of first choice for this disease. The degree of lesion adhesion to the brain stem and peripheral vessels determines the degree of tumor resection and prognosis of patients.

Download Full-text

NCMP-13. LEPTOMENINGEAL DISEASE FOLLOWING RESECTION OF INTRAVENTRICULAR MELANOMA METASTASIS DIAGNOSED THROUGH CIRCULATING TUMOR CELLS

Neuro-Oncology ◽

10.1093/neuonc/noaa215.524 ◽

2020 ◽

Vol 22 (Supplement_2) ◽

pp. ii125-ii125

Author(s):

Christopher Wang ◽

Melissa Limia ◽

Peter Forsyth ◽

James Liu

Keyword(s):

Early Intervention ◽

Tumor Cells ◽

Circulating Tumor Cells ◽

Surgical Resection ◽

Tumor Resection ◽

Leptomeningeal Disease ◽

Melanoma Metastasis ◽

Tumor Seeding ◽

Csf Analysis ◽

Dismal Prognosis

Abstract Leptomeningeal disease in the setting of malignant melanoma metastatic to the brain provides a dismal prognosis. The relationship between intraventricular metastatic tumor seeding following surgical resection and development of leptomeningeal disease (LMD) is not completely clear, although there appears to be correlation. While the mechanisms that drive the development of LMD is not well understood, monitoring of cerebrospinal fluid (CSF) for circulating tumor cells (CTCs) in high risk patients may allow for early intervention for LMD prior to radiographical diagnosis. This report describes a patient with metastatic melanoma who developed ventricular trapping from an intraventricular melanoma metastasis. The patient underwent endoscopic assisted resection of the tumor. Due to concern for leptomeningeal seeding given the location of the tumor and use of surgical resection, CSF analysis was performed. CTC count was increased shortly after surgical resection along with cytology that was suspicious for malignancy. Due to the increase in CTCs, the patient was treated for LMD with whole brain radiation therapy and intrathecal pembrolizumab. Subsequent CSF analysis revealed clearing of malignant cells in the CSF. The patient developed symptoms consistent with LMD approximately 9 months after the surgery and died 21 months after resection of his brain metastasis. This case illustrates a rare occurrence of an intraventricular melanoma metastasis, and the use of CTC presence within the CSF to diagnose LMD for early intervention. This emphasizes that the risk of developing LMD must be considered with intraventricular metastasis or ventricular exposure during tumor resection, and that CTCs may be an effective factor to monitor for early development of disease with possible prolonged survival benefit.

Download Full-text

Treatment of tumor thrombus in the superior mesenteric vein due to advanced colon cancer with complete surgical resection and chemotherapy: a case report

Surgical Case Reports ◽

10.1186/s40792-020-01091-6 ◽

2020 ◽

Vol 6 (1) ◽

Author(s):

Yoshitsugu Yanagida ◽

Takahiro Amano ◽

Ryuji Akai ◽

Akira Toyoshima ◽

Jotaro Kobayashi ◽

...

Keyword(s):

Colon Cancer ◽

Liver Metastasis ◽

Surgical Resection ◽

Tumor Thrombus ◽

Superior Mesenteric Vein ◽

Tumor Resection ◽

Term Survival ◽

Mesenteric Vein ◽

Advanced Colon Cancer ◽

Complete Surgical Resection

Abstract Background Tumor thrombus in the superior mesenteric vein secondary to colon cancer is rare. We report a case of tumor thrombus in the superior mesenteric vein and liver metastasis due to advanced colon cancer that was treated with chemotherapy and complete surgical resection. Case presentation A 72-year-old man after transverse colectomy with lymph node dissection for advanced colon cancer was diagnosed with tumor thrombus in the superior mesenteric vein and liver metastasis. He underwent adjuvant chemotherapy and had complete surgical tumor resection involving tumor thrombectomy and hepatectomy. There has been no recurrence at 36 months after surgery. Conclusion Herein, we report a rare case of tumor thrombus in the superior mesenteric vein related to advanced colon cancer. The combination of chemotherapy and complete surgical tumor resection may provide long-term survival.

Download Full-text

Granular Cell Tumor: A Technical Approach for Resection of a Rare Suprasellar Mass

Neurosurgery Open ◽

10.1093/neuopn/okaa010 ◽

2020 ◽

Vol 1 (4) ◽

Author(s):

Alexander J Schupper ◽

Frank J Yuk ◽

Hongyan Zou ◽

Sadhna Ahuja ◽

Nadejda M Tsankova ◽

...

Keyword(s):

Surgical Resection ◽

Granular Cell Tumor ◽

Clinical Presentation ◽

Granular Cell ◽

Cell Tumor ◽

Patient Specific ◽

Surgical Approaches ◽

Technical Approach ◽

Multiple Strategies ◽

Current State

Abstract BACKGROUND AND IMPORTANCE Granular cell tumors (GCTs) of the sellar and suprasellar regions are rare tumors that may be managed surgically by multiple strategies. The technical approaches for these tumors have rarely been described in the literature. CLINICAL PRESENTATION We introduce the case of a patient presenting with dizziness and headaches who was found to have a suprasellar and retrochiasmatic mass and eventually underwent surgical resection. We discuss the characteristics of this tumor, and the current state of the literature. Also included are details regarding the surgical approach utilized in this case, and a discussion of the various surgical approaches for this type of tumor. CONCLUSION There are several approaches for the surgical resection of suprasellar GCTs, and the approach utilized may depend on patient and/or surgeon considerations. Patient-specific considerations must be made to ensure maximal safe resection of these lesions.

Download Full-text

Prionopathies and Prionlike Protein Aberrations in Neurodegenerative Diseases

Neurographics ◽

10.3174/ng.2000035 ◽

2021 ◽

Vol 11 (2) ◽

pp. 127-148

Author(s):

K.N. Anderson ◽

W.B. Overcast ◽

J.R. Brosch ◽

B.D. Graner ◽

M.C. Veronesi

Keyword(s):

Neurodegenerative Diseases ◽

Protein Misfolding ◽

Clinical Presentation ◽

Prion Diseases ◽

Imaging Biomarkers ◽

Amyloid Pet ◽

Imaging Features ◽

Jakob Disease ◽

The Common ◽

Neuro Imaging

Protein misfolding has been an area of intense research and is implicated in a number of neurodegenerative diseases. Key proteins in the brain lose their native ability to fold and instead assume abnormal conformations. Misfolded proteins cluster to form pathologic aggregates, which cause cellular dysfunction, neuronal death, and neurodegeneration. The prionopathies are best known among the neurodegenerative diseases for their ability to misfold, self-propagate, and infect other organisms. There is increasing evidence of a rationale for a prionlike mechanism of spread of other neurodegenerative diseases through a similar seeding mechanism. In this review, we detail the role of a key protein aberration known to the various prion diseases, including sporadic, variant, and iatrogenic Creutzfeldt-Jakob disease; variably protease-sensitive prionopathy; Gerstmann-Straussler-Scheinker disease; fatal familial insomnia; and kuru. We also discuss the clinical presentation, the available, and emerging imaging options for these diseases. In the second part of this review, we delineate how a prionlike seeding process may be driving the progression of other neurodegenerative diseases, including Parkinson disease, Alzheimer disease, and Huntington disease. A discussion of clinical presentation and imaging features of these example diseases follows to make a case for a common approach to developing imaging biomarkers and therapies of these diseases.Learning Objective: Upon completion of this article, one should be able to describe the various types of prion diseases, recognize and identify the common the neuro-imaging findings in prion diseases, describe seeding mechanism of prion disease, list the common amyloid PET tracers used for Alzheimer’s disease, and list common imaging biomarkers in neurodegenerative diseases.

Download Full-text

Subungual Glomus Tumor- Clinical Presentation And Treatment

Bangladesh Journal of Plastic Surgery ◽

10.3329/bdjps.v3i2.18250 ◽

2014 ◽

Vol 3 (2) ◽

pp. 45-48 ◽

Cited By ~ 1

Author(s):

Shyamal Chandra Debnath ◽

Suman Kumar Roy ◽

RR Kairy

Keyword(s):

Soft Tissue ◽

Soft Tissue Tumor ◽

Clinical Presentation ◽

Glomus Tumor ◽

Rare Condition ◽

Surgical Excision ◽

Tissue Mass ◽

Delay In Diagnosis ◽

Nail Deformity

Glomus tumor is a rare condition and constitutes only 1 % of all soft tissue tumor of body. Glomus tumor is familiar for its unusual presentation and long standing symptoms due to delay in diagnosis. Authors have presented the clinical behavior and treatment of 7 patients with subungual soft tissue mass. Following surgical excision, all patients cured of symptoms, at the end of follow up, no recurrence occurred; post operative nail deformity was insignificant. DOI: http://dx.doi.org/10.3329/bdjps.v3i2.18250 Bangladesh Journal of Plastic Surgery July 2012, 3(2): 45-48

Download Full-text

Clinical and Imaging Features of a Congenital Midline Cervical Cleft in a Neonate: A Rare Anomaly

Case Reports in Pediatrics ◽

10.1155/2015/439596 ◽

2015 ◽

Vol 2015 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

Rachelle Goldfisher ◽

Pritish Bawa ◽

Zachary Ibrahim ◽

John Amodio

Keyword(s):

Congenital Anomaly ◽

Pediatric Surgery ◽

Clinical Presentation ◽

Imaging Features ◽

Rare Congenital Anomaly ◽

Rare Anomaly ◽

Work Up ◽

Midline Cervical Cleft

Congenital midline cervical cleft (CMCC) is a rare congenital anomaly. CMCC and its complications and treatment have been well described in ENT, dermatology, and pediatric surgery literature. However, to our knowledge, the imaging work-up has not been reported in the literature thus far. We present a case of CMCC in a neonate with description of clinical presentation and imaging features.

Download Full-text