Four Flu Pandemics: Lesson that Cannot be Learned

2021 ◽  
pp. 0169796X2110472
Author(s):  
Ronn Pineo

This article explores the history of influenza, focusing on the four major flu pandemics in the last century and a half, outbreaks starting in 1889, 1918, 1957, and 1968. The article looks closely at flu etiology and the historical puzzles over which flu subtype was responsible for each major outbreak. Some mysteries regarding pandemic influenza remain, with core questions stubbornly refusing to yield answers. This article seeks to explore the history of flu in the hope that we can take away some lessons learned as we try to get ready for potential future flu pandemics.

2021 ◽  
Vol 46 (1) ◽  
pp. 252-267
Author(s):  
Rashmi Dyal-Chand

Preemption is one of the most important legal doctrines for today’s progressives to understand because of its power to constrain progressive policymaking and social movement lawyering at the state and local level. By examining the detailed history of a decades-long campaign by the labor and environmental movements to improve working conditions in an industry at the heart of the global supply chain, Scott L. Cummings’s Blue and Green: The Drive for Justice at America’s Port (2018) provides a case study about the doctrine and impacts of preemption. The study also inspires lawyers and activists alike to reexamine core questions of factual relevance, representation and voice, and precedent.


2012 ◽  
Vol 33 (4_suppl3) ◽  
pp. S281-S292 ◽  
Author(s):  
James P. Wirth ◽  
Arnaud Laillou ◽  
Fabian Rohner ◽  
Christine A. Northrop-Clewes ◽  
Barbara Macdonald ◽  
...  

Background Fortification of staple foods has been repeatedly recommended as an effective approach to reduce micronutrient deficiencies. With the increased number of fortification projects globally, there is a need to share practical lessons learned relating to their implementation and responses to project-related and external challenges. Objective To document the achievements, challenges, lessons learned, and management responses associated with national fortification projects in Morocco, Uzbekistan, and Vietnam. Methods Independent end-of-project evaluations conducted for each project served as the primary data source and contain the history of, and project activities undertaken for, each fortification project. Other sources, including national policy documents, project reports from the Global Alliance for Improved Nutrition (GAIN) and other stakeholders, industry assessments, and peer-reviewed articles, were used to document the current responses to challenges and future project plans. Results All projects had key achievements related to the development of fortification standards and the procurement of equipment for participating industry partners. Mandatory fortification of wheat flour was a key success in Morocco and Uzbekistan. Ensuring the quality of fortified foods was a common challenge experienced across the projects, as were shifts in consumption patterns and market structures. Adjustments were made to the projects' design to address the challenges faced. Conclusions National fortification projects are dynamic and must be continually modified in response to specific performance issues and broader shifts in market structure and consumption patterns.


2012 ◽  
Vol 33 (2) ◽  
pp. E11 ◽  
Author(s):  
Paul J. Schmitt ◽  
John A. Jane

The history of endoscopic third ventriculostomy (ETV) demonstrates the importance of studying neurosurgery's history. A story that began with numerous technological advancements started to fizzle as neurosurgeons were stymied by problems encountered during the infancy of the technology they were still developing. The new technique, although sound in theory, failed to deliver a realistic solution for managing hydrocephalus; it lost the battle to the valved shunt. Over the last 15–20 years, a clearer understanding of pathophysiological mechanisms underlying various forms of hydrocephalus, along with effective implementation of evidence-based practice, has allowed for optimization of patient selection and a remarkable improvement in ETV success rates. Neurosurgeons would be wise to take the lessons learned in modernizing the ETV procedure and reassure themselves that these lessons do not apply to other methods that are tempting to dismiss as antiquated or archaic.


1994 ◽  
Vol 8 (1) ◽  
pp. 19-28 ◽  
Author(s):  
William A. Weimer

One of the most significant cooperative industry–higher education projects in Europe during the past decade has been EuroPACE, the European Programme of Advanced Continuing Education. In January 1993, EuroPACE ceased its broadcasts and re-entered the planning process. By the time this article has been published, EuroPACE should again be broadcasting, but with a somewhat different format and content. In this article, Bill Weimer presents a brief history of the first five years of EuroPACE and analyses the project. He examines key assumptions and decisions made, points out those which now appear to have been in error, and lists the lessons learned. Many of the assumptions and decisions made were correct; some of these are also discussed. This article will contribute the experience and lessons learned by EuroPACE to other joint industry–higher education projects. It may help them to avoid making some of the same mistakes.


2021 ◽  
Vol 6 (1) ◽  
pp. 429-446
Author(s):  
Katarzyna Sygulska

The article presents the life story of an elderly woman, the sense of the quality of her life, the critical events that shaped her life, and the lessons learned from her experiences. The study adopted a biographical paradigm, which explains the importance of individual biographies in the education process and indicates the need to study the history of life as a source of knowledge about man and his learning. The main aim of the undertaken research was to recognise the meanings that the respondent gives to critical events in shaping the quality of her life. The biographical method was used, and, within it, an autobiographical narrative interview. The most significant events assessed as positive were the births of her children. The negative events were in particular: the deaths of close ones, a failed marriage and an accident. In coping with suffering, the woman was helped by: help from others, faith, strength, optimism, activity, activities for the benefit of others, and her value system. Lessons emerged from the subject’s history, helpful in her life, which can also inspire others. The narrator tried to live in harmony with her conscience and the accepted principles, which gave her satisfaction. Biographical research has an educational function. Life stories can teach what is important in life, what is worth living for, and they can lead to reflections.


2021 ◽  
Vol 9 ◽  
Author(s):  
Audrey C. Woerner ◽  
Renata C. Gallagher ◽  
Jerry Vockley ◽  
Aashish N. Adhikari

Newborn screening (NBS) is a population-based program with a goal of reducing the burden of disease for conditions with significant clinical impact on neonates. Screening tests were originally developed and implemented one at a time, but newer methods have allowed the use of multiplex technologies to expand additions more rapidly to standard panels. Recent improvements in next-generation sequencing are also evolving rapidly from first focusing on individual genes, then panels, and finally all genes as encompassed by whole exome and genome sequencing. The intersection of these two technologies brings the revolutionary possibility of identifying all genetic disorders in newborns, allowing implementation of therapies at the optimum time regardless of symptoms. This article reviews the history of newborn screening and early studies examining the use of whole genome and exome sequencing as a screening tool. Lessons learned from these studies are discussed, along with technical, ethical, and societal challenges to broad implementation.


2010 ◽  
Vol 15 (45) ◽  
Author(s):  
M Aho ◽  
O Lyytikaïnen ◽  
J E Nyholm ◽  
T Kuitunen ◽  
E Rönkkö ◽  
...  

In September 2009, an outbreak of 2009 pandemic influenza A(H1N1) took place in a Finnish garrison. In November 2009, we performed a serological survey among 984 recruits undergoing their military service at the garrison and related the results to self-reported upper respiratory tract infection (URTI) with or without fever. Of 346 volunteers who donated a blood sample, 169 (49%) had pandemic influenza A(H1N1) virus-specific antibodies. Of those, 84 (50%) reported no recent history of URTI, suggesting that a major part of those infected with pandemic influenza A(H1N1) virus may be asymptomatic.


2008 ◽  
Vol 12 (3-4) ◽  
pp. 359-370 ◽  
Author(s):  
Corinne Watts ◽  
Ian Stringer ◽  
Greg Sherley ◽  
George Gibbs ◽  
Chris Green

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