Gluteal muscle damage and rhabdomyolysis after olanzapine poisoning: a case report

Olanzapine is a widely adopted atypical antipsychotic medication used to manage schizophrenia. Reports show that the incidence rate of adverse reactions to olanzapine is significantly lower than those of other classic antipsychotic medications. However, olanzapine overdose may be associated with severe consequences. Herein, we report a 21-year-old female patient who had taken nearly 700 mg (70 tablets) of olanzapine; she was found after 30 hours. As her condition progressed, she presented with rhabdomyolysis, swelling in the thighs and hips, paralytic ileus, digestive tract hemorrhage, and elevated serum amylase and lipase levels; notably, she recovered after treatment. This intractable case is of great clinical significance and suggests that early-phase hemoperfusion plays a critical role in olanzapine poisoning-related rhabdomyolysis.

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Anti-inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report

Journal of Medical Case Reports ◽

10.1186/1752-1947-4-6 ◽

2010 ◽

Vol 4 (1) ◽

Cited By ~ 9

Author(s):

Bernhard T Baune ◽

Harris Eyre

Keyword(s):

Case Report ◽

Major Depression ◽

Atypical Antipsychotic ◽

Antipsychotic Medication ◽

Anti Inflammatory ◽

Atypical Antipsychotic Medication

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Minimizing antipsychotic medication obviated the need for enema against severe constipation leading to paralytic ileus: a case report

Journal of Clinical Pharmacy and Therapeutics ◽

10.1111/j.1365-2710.2007.00843.x ◽

2007 ◽

Vol 32 (5) ◽

pp. 525-527 ◽

Cited By ~ 9

Author(s):

T. Suzuki ◽

H. Uchida ◽

K. Watanabe ◽

H. Kashima

Keyword(s):

Case Report ◽

Antipsychotic Medication ◽

Paralytic Ileus ◽

Severe Constipation

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A rare coexistence of acromegaly, myasthenia gravis, sicca syndrome, and elevated serum IgG4 levels: A single case report

Endocrine Abstracts ◽

10.1530/endoabs.70.aep708 ◽

2020 ◽

Author(s):

Wan-Chen Wu ◽

Huang Abel Po-Hao

Keyword(s):

Case Report ◽

Myasthenia Gravis ◽

Single Case ◽

Elevated Serum ◽

Sicca Syndrome ◽

Single Case Report ◽

Serum Igg4

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Paliperidone induced neutropenia in first episode psychosis: a case report

BMC Psychiatry ◽

10.1186/s12888-021-03073-w ◽

2021 ◽

Vol 21 (1) ◽

Cited By ~ 1

Author(s):

Natalie Martos ◽

William Hall ◽

Alicia Marhefka ◽

Thomas W. Sedlak ◽

Frederick C. Nucifora

Keyword(s):

Adverse Effect ◽

Case Report ◽

The United States ◽

First Episode Psychosis ◽

Potential Adverse Effect ◽

Severe Neutropenia ◽

First Episode ◽

Antipsychotic Medications ◽

Increased Risk ◽

Episode Psychosis

Abstract Background Neutropenia, a decrease in total number of neutrophils below 1500/mm3 and particularly severe neutropenia, defined as neutrophils less than 500/mm3, is a potential adverse effect of antipsychotic medications that can lead to increased risk of infections and death. However, much of the attention on the potential adverse effect is centered exclusively on clozapine, which remains the only antipsychotic medication in the United States requiring standardized monitoring of blood work. We demonstrate here that paliperidone can also cause neutropenia and therefore clinicians should be aware of this possibility especially during initiation of treatment. Case presentation The following report presents the case of a 23-year-old African American male with first episode psychosis who developed neutropenia after initiation of paliperidone. Neutropenia resolved after discontinuation of paliperidone and initiation of an alternative antipsychotic, haloperidol. Conclusions This case report demonstrates an example of paliperidone induced neutropenia which resolved with a switch to haloperidol. We conclude that when initiating paliperidone, clinicians should be more aware of the risk of neutropenia. Moreover, neutropenia may be a more common and overlooked issue in patients on antipsychotic medications other than clozapine and increased awareness of comparative risk across antipsychotics could help direct treatment.

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Crime Scene Analysis Through DNA Testing of Canine Feces—A Case Report

Academic Forensic Pathology ◽

10.1177/1925362120944743 ◽

2020 ◽

Vol 10 (1) ◽

pp. 56-61

Author(s):

Vishal Somnay ◽

Thomas Duong ◽

Ray-Young Tsao ◽

Joseph A. Prahlow

Keyword(s):

Case Report ◽

Epithelial Cells ◽

Critical Role ◽

Crime Scene ◽

Scene Analysis ◽

Dna Testing ◽

Forensic Dna ◽

Forensic Dna Testing ◽

Positive Results ◽

Crime Scene Analysis

Forensic DNA testing can play a critical role in homicide investigations. Selecting the appropriate evidence on which to perform DNA testing requires foresight and reasoning based on experience and science. Although successful DNA testing can occur using many substrates, including blood, hair, and sweat/epithelial cells, positive results can also result from testing various unorthodox samples. The authors report on a triple-murder investigation where DNA testing of dog feces at the crime scene matched DNA testing of feces found on the shoe of a suspect resulting in successful prosecution of the case.

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