Biological Activity of Low-Molecular Weight Dextran 40. The Effect on Serum Proteins, Plasma Blood Clotting Factors and Erythrocyte Sedimentation Rate
1973 ◽
Vol 1
(3)
◽
pp. 194-203
Keyword(s):
Dextran 40 infused in doses from 1.2 to 1.5 g/kg body weight decreases the concentration of proteins in the plasma and reduces the total amount of circulating protein. Dextran 40 in vitro precipitates high-molecular weight proteins participating in blood clotting, such as factor VIII and fibrinogen and, if infused, decreases their plasma levels. Addition in vitro of Dextran 40 to blood with a high ESR reduces the value proportionally to the concentration of dextran in the blood sample: after infusion of Dextran 40 the ESR decreases by a mean value of 19.9% after infusion of 500 ml and by 36.2% after 1000 ml. No bleeding was noted with these infusions.
1971 ◽
Vol 17
(11)
◽
pp. 1109-1113
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1982 ◽
Vol 48
(02)
◽
pp. 120-124
◽
1994 ◽
Vol 72
(06)
◽
pp. 942-946
◽
1967 ◽
Vol 18
(03/04)
◽
pp. 634-646
◽
1986 ◽
Vol 56
(03)
◽
pp. 318-322
◽
1983 ◽
Vol 43
(6)
◽
pp. 521-526
◽