Intraoperative Sentinel Node Detection by an Innovative Imaging Probe

2002 ◽  
Vol 88 (3) ◽  
pp. S56-S58 ◽  
Author(s):  
C Campisi ◽  
A Soluri ◽  
S Stella ◽  
G Valenti ◽  
F Scopinaro
Keyword(s):  
Breast Cancer ◽  
Minimally Invasive Surgery ◽  
Clinical Practice ◽  
Soft Tissue ◽  
Sentinel Node ◽  
Breast Cancer Treatment ◽  
Visual Guidance ◽  
Sentinel Node Detection ◽  
Sentinel Nodes ◽  
Imaging Probe

Intraoperative tumor detection has been used in many applications, and today the sentinel node technique is a widely employed surgical procedure in breast cancer. Different detector systems are employed but several problems have been reported in clinical practice, in particular the difficulty to accurately detect the sentinel node within the axillary soft tissue. The problem is even greater for abdominal and thoracic tumors. We propose an innovative Imaging Probe (IP) able to visualize on a monitor the primary tumor and secondary lesions, if appropriately radiolabeled. The IP can be optimally applied for minimally invasive surgery in breast cancer treatment, and a preliminary experience related to 15 patients and 20 sentinel nodes is reported here. We compared the results obtained with the IP to those obtained with an Anger camera and a traditional scintillation detector, and found them to be very promising. In particular the surgeon's work is greatly facilitated by direct visual guidance instead of a generic acoustic signal.

Sentinel node detection with radiocolloid lymphatic mapping in early invasive cervical cancer

2005 ◽  
Vol 15 (2) ◽  
pp. 273-277 ◽  
Author(s):  
Y. S. Lin ◽  
C. C. Tzeng ◽  
K. F. Huang ◽  
C. Y. Kang ◽  
C. C. Chia ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Lymph Node ◽  
Sentinel Node ◽  
Lymph Node Metastases ◽  
Lymphatic Mapping ◽  
Invasive Cervical Cancer ◽  
False Negative ◽  
Sentinel Node Detection ◽  
Sentinel Nodes ◽  
Node Metastases

We assessed the feasibility of sentinel lymph node detection using technicium-99 radiocolloid lymphatic mapping for predicting lymph node metastases in early invasive cervical cancer. Thirty patients with cervical cancer (stages IA2–IIA) underwent preoperative lymphoscintigraphy using technicium-99 intracervical injection and intraoperative lymphatic mapping with a handheld gamma probe. After dissection of the sentinel nodes, the standard procedure of pelvic lymph node dissection and radical hysterectomy was performed as usual. The sentinel node detection rate was 100% (30/30). There were seven (23.3%) cases of microscopic lymph node metastases on pathologic analysis. All of them had sentinel node involvement. Therefore, the sensitivity of sentinel node identification for prediction of lymph node metastases was 100%, and no false negative was found. Preoperative lymphoscintigraphy, coupled with intraoperative lymphatic mapping, located the sentinel nodes accurately in our study patients. This sentinel node detection method appears to be feasible for predicting lymph node metastases

SentiDose Trial: Optimizing dose and injection timing in magnetic sentinel node detection for early breast cancer

2020 ◽  
Vol 138 ◽  
pp. S45
Author(s):  
A. Karakatsanis ◽  
L. Pistioli ◽  
R.Olofsson Bagge ◽  
A. Hersi ◽  
C.Luberth Dussan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Sentinel Node ◽  
Early Breast Cancer ◽  
Injection Timing ◽  
Sentinel Node Detection

scholarly journals Sentinel Node Detection in Head and Neck Malignancies: Innovations in Radioguided Surgery

2009 ◽  
Vol 2009 ◽  
pp. 1-10 ◽  
Author(s):  
L. Vermeeren ◽  
W. M. C. Klop ◽  
M. W. M. van den Brekel ◽  
A. J. M. Balm ◽  
O. E. Nieweg ◽  
...  
Keyword(s):  
Sentinel Node ◽  
Head And Neck ◽  
Scientific Progress ◽  
Neck Region ◽  
Diagnostic Tools ◽  
Lymph Node Status ◽  
Radioguided Surgery ◽  
Sentinel Node Detection ◽  
Head And Neck Region ◽  
Sentinel Nodes

Sentinel node mapping is becoming a routine procedure for staging of various malignancies, because it can determine lymph node status more precisely. Due to anatomical problems, localizing sentinel nodes in the head and neck region on the basis of conventional images can be difficult. New diagnostic tools can provide better visualization of sentinel nodes. In an attempt to keep up with possible scientific progress, this article reviews new and innovative tools for sentinel node localization in this specific area. The overview comprises a short introduction of the sentinel node procedure as well as indications in the head and neck region. Then the results of SPECT/CT for sentinel node detection are described. Finally, a portable gamma camera to enable intraoperative real-time imaging with improved sentinel node detection is described.

scholarly journals Breast cancer treatment in clinical practice compared to best evidence and practice guidelines

2004 ◽  
Vol 90 (1) ◽  
pp. 26-30 ◽  
Author(s):  
B S Bloom ◽  
N de Pouvourville ◽  
S Chhatre ◽  
R Jayadevappa ◽  
D Weinberg
Keyword(s):  
Breast Cancer ◽  
Clinical Practice ◽  
Cancer Treatment ◽  
Practice Guidelines ◽  
Breast Cancer Treatment
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