Coolsense® versus EMLA® for peripheral venous cannulation in adult volunteers: A randomised crossover trial

2021 ◽  
pp. 0310057X2110392
Author(s):  
Dilraj Thind ◽  
Stephen J Roberts ◽  
Benjamin FH van der Griend
Keyword(s):  
Confidence Intervals ◽  
Crossover Trial ◽  
Rating Scale ◽  
Medical Procedure ◽  
Venous Cannulation ◽  
Pain Rating ◽  
Paired Difference ◽  
Numerical Pain Rating Scale ◽  
Adult Volunteers ◽  
Pain Rating Scale

Peripheral venous cannulation (PVC) is a commonly performed invasive medical procedure. Topical treatments such as the eutectic mixture of local anaesthetics (EMLA®, Aspen Pharmacare Australia Pty Ltd, St Leonards, NSW) attenuate the associated pain, but are limited by requiring up to one hour of application before becoming effective. The Coolsense® (Coolsense Medical Ltd., Tel Aviv, Israel) pain numbing applicator is a new device using a cryoanalgesic means to anaesthetise skin within seconds. Coolsense is being increasingly used for cannulation, but comparative studies are lacking. We recruited 64 healthy adult volunteers to this open-label two sequence, two period randomised crossover trial. Participants had two 20 gauge venous cannulae inserted, one on the dorsum of each hand. Each cannulation attempt was preceded by treatment with Coolsense or an EMLA patch containing 2.5% lidocaine and 2.5% prilocaine. The primary outcome was participant pain using the 0–10 numerical pain rating scale. Secondary outcomes were participant satisfaction scores on a 0–10 scale, treatment preference, and failed cannulation attempts. Participants were randomly assigned to either the Coolsense EMLA ( n = 32) or EMLA Coolsense ( n = 32) sequence. All participants completed the trial. The pooled mean paired difference of the numerical pain rating scale was –1.84 (95% confidence intervals –1.28 to –2.41; P < 0.001) in favour of EMLA. The pooled mean paired difference for satisfaction score was 2.26 (95% confidence intervals 1.46 to 3.07; P < 0.001) higher with EMLA. Most participants preferred EMLA over Coolsense ( P < 0.001). There was no significant difference regarding failed cannulation between the two treatments ( P = 0.14). Among healthy individuals undergoing elective PVC, EMLA was associated with reduced pain, increased satisfaction, and was the preferred treatment compared to Coolsense.

scholarly journals Effectiveness of Strengthening and Aerobic Exercises among Geriatrics with Arthritis

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 593-598
Author(s):  
Tamilselvi S ◽  
Anshu Gloria Ekka ◽  
Arul Jothi L
Keyword(s):  
Aerobic Exercise ◽  
Rating Scale ◽  
Nursing Intervention ◽  
Control Group ◽  
Research Approach ◽  
Intensity Level ◽  
Pain Rating ◽  
Numerical Pain Rating Scale ◽  
Pain Rating Scale ◽  
Experimental Group

Joint inflammation might be a term regularly acclimated mean any confusion that influences joints. Manifestations for the most part, incorporate joint torment and firmness. Different manifestations may incorporate redness, warmth, growing, the diminished scope of movement of the influenced joints. The aim of the study is to determine the effectiveness of strengthening and aerobic exercise among geriatrics with arthritis. A quantitative research approach with a quasi-experimental research design was used for the present study. A total of 60 arthritis clients who fall in the inclusion criteria were selected by purposive sampling technique, among which 30 samples were in the experimental group and 30 in the control group. The data were collected for both the groups, followed by the pre-test was conducted on the 1st day, the intensity level of pain was assessed by the numerical pain rating scale followed by the exercises which are effective in arthritis are a range of motion exercise, strengthening exercises (hand towel knee exercises, knee flexion, long arc quads), aerobic exercise (brisk walking) was initiated only in the experimental group. The post-test was conducted on 7th day and the level of pain was assessed by a numerical pain rating scale in both the groups. The results revealed that there was a significant reduction in the level of pain at p<0.0001 after the intervention among the experimental group. Thus, the study proves that strengthening and aerobic exercises can be used as an effective nursing intervention for reducing the arthritis pain among the geriatrics and it is easily applicable exercises, and also considered as a less cost-effective. These exercises can be practiced at home without any stress or harm and it has less side effect as compared to that of pharmacological interventions. 

scholarly journals Effectiveness of Progressive Resisted Exercise along with Conventional Exercise and Conventional Exercise Program alone in Subjects with Text Neck Syndrome

2021 ◽  
pp. 536-542
Author(s):  
Divya Jain ◽  
Swapna Jawade ◽  
Neha Chitale
Keyword(s):  
Neck Pain ◽  
Pain Intensity ◽  
Conventional Therapy ◽  
Rating Scale ◽  
Neck Disability Index ◽  
Exercise Program ◽  
Pain Rating ◽  
Numerical Pain Rating Scale ◽  
Neck Disability ◽  
Pain Rating Scale

Background: "Text neck" is a term coined to describe the posture created by leaning forward for lengthy periods of time, such as when reading and texting on a cellphone which has been linked to stress injuries. Neck pain, upper back discomfort, shoulder pain, frequent headaches, and greater curvature of the spine are all dangerous indications of text neck. According to a survey, 35% of smartphone users suffer from text neck syndrome. People between the ages of 15 and 18 are more likely to have neck pain. This protocol has been created that describes the design of comparative study to evaluate effectiveness of progressive resisted exercise along with conventional exercise and conventional exercise program alone in text neck syndrome. Methods: The participants (n=80) will be recruited in the study suffering from text neck syndrome and meeting the inclusion criteria. Two groups will be formed such that patients in group A will be treated with conventional therapy and group B will be treated with progressive resisted exercise (PRE) along with conventional therapy. The protocol will cover 4 weeks of treatment. In the rehabilitation period, we will evaluate the pain intensity, strength of neck muscles and functional activity. Our outcome measures will be- Numerical pain rating scale (NPRS) and Neck disability index (NDI). Discussion: Efficacy of the intervention will be evaluated by analyzing the pain intensity by using Numerical pain rating scale (NPRS) and level of functional disability by using Neck disability index (NDI). The result of the study will significantly provide affirmation on either using combination therapy of PRE with conventional exercise or conventional exercise alone.

scholarly journals Effectiveness of Cryotherapy on Pain Reduction During Arteriovenous Fistula Puncture Among Patients Undergoing Hemodialysis

2020 ◽  
Vol 11 (3) ◽  
pp. 4314-4317
Author(s):  
Thamu Priyadharshini N T
Keyword(s):  
Rating Scale ◽  
Life Support ◽  
Pain Reduction ◽  
Control Group ◽  
Pain Rating ◽  
Av Fistula ◽  
Numerical Pain Rating Scale ◽  
Significant Difference ◽  
Pain Rating Scale ◽  
Experimental Group

Dialysis is performed as critical life support when the patient is suffering acute and chronic kidney failure. The study focus on to determine effectiveness of on pain reduction during AV fistula puncture among patients undergoing . The population comprised of patients in . Experimental Research design was utilized for this study. The investigators assess the pain on AV fistula puncture among the patients with the assistance of numerical pain rating scale, Sixty samples (30 experimental group and 30 control group)were selected by probability simple random (Numerical table method)sampling technique, the data was gathered through the Numerical Pain Rating scale and demographic variables. The pain on AV fistula puncture of the experimental group and control group were calculated by paired’ test for experimental group (‘t’ = 18) and in control group, (‘t’ =1.5). This proves that there is a significant difference in test and post test levels of pain on AV fistula puncture in the experimental group at 0.05 levels. It indicated that the given was effective. The implication of the findings indicated that given was effective for pain reduction during AV fistula puncture among patients. : , pain on AV fistula puncture, patients. implication of the findings indicated that given was effective for pain reduction during AV fistula puncture among patients.

scholarly journals EFEKTIVITAS DAN EFEK SAMPING PENGGUNAAN GABAPENTIN PADA PASIEN NEUROPATI DIABETIK DI RSUP DR. WAHIDIN SUDIROHUSODO MAKASSAR

2018 ◽  
Vol 22 (2) ◽  
pp. 44-47
Author(s):  
Zhulhajsyirah Zhulhajsyirah ◽  
Elly Wahyudin ◽  
Jumriani Tammas
Keyword(s):  
Rating Scale ◽  
P Value ◽  
Pain Rating ◽  
Numerical Pain Rating Scale ◽  
Pain Rating Scale

Penelitian ini bertujuan untuk mengetahui dan menganalisis efektivitas  penggunaan gabapentin  terhadap penurunan derajat nyeri pada  pasien neuropati diabetik di  RSUP Wahidin Sudirohusodo Makassar  yang diukur dengan menggunakan instrumen  Numerical Pain Rating Scale (NPRS) efek samping  penggunaan  gabapentin   pada  pasien neuropati diabetik di  RSUP DR. Wahidin Sudirohusodo Makassar. Penelitian ini dilaksanakan di Poliklinik Saraf dan Poliklinik Endokrin Instalasi Rawat Jalan RSUP DR. Wahidin Sudirohusodo Makassar pada bulan april-juni 2018. Jenis penelitian ini adalah penelitian observasional non eksperimental dengan  desain penelitian  cros sectional. Metode yang digunakan dalam penelitian ini adalah dengan melakukan wawancara dan pengukuran skala nyeri pada pasien neuropati diabetik. Data dianalisis dengan menggunakan analisis statistik uji Wicoxon Signed Ranks Test. Hasil penelitian menunjukkan bahwa efek terapi gabapentin sebelum dan sesudah   pemberian pada 21 pasien neuropati diabetik menunjukkan adanya penurunan skala nyeri  dengan penurunan rata-rata sebesar 2,14 dengan nilai  p-value<0,05 yang berarti  berbeda secara signifikan dalam menurunkan nyeri neuropati. Sedangkan Efek Samping yang terjadi setelah pemberian gabapentin yaitu, mengantuk dan pusing 14%, mengantuk 29%, pusing 5% dan tidak mengalami efek samping 52%.

Effectiveness of transcutaneous electrical nerve stimulation as an adjunct to selected physical therapy exercise program on male patients with pudendal neuralgia: A randomized controlled trial

2021 ◽  
pp. 026921552199533
Author(s):  
Marwa M Eid ◽  
Mohamed F Rawash ◽  
Moussa A Sharaf ◽  
Hadaya Mosaad Eladl
Keyword(s):  
Physical Therapy ◽  
Rating Scale ◽  
Exercise Program ◽  
Control Group ◽  
Study Group ◽  
Pain Rating ◽  
Pudendal Neuralgia ◽  
Numerical Pain Rating Scale ◽  
Male Patients ◽  
Pain Rating Scale

Objective: To assess the effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) combined with selected physical therapy exercise program on male patients with pudendal neuralgia. Design: A double-blinded randomized controlled study. Setting: Out-patient setting. Participants: Fifty-two male participants with pudendal neuralgia (30–50 years) were allocated randomly into two groups; study and control. The same physical therapy exercises were applied to all participants, plus the same prescribed analgesic medication (Etodolac). Participants in the study group received additional TENS and sham TENS were given to those in control group. Intervention: Intervention lasted for 12 weeks, three sessions per week (60 minutes/session). Outcome measures: Numerical pain rating scale and daily Etodolac intake dose were measured before and after intervention. Results: Statistically significant differences were detected in numerical pain rating scale and daily Etodolac intake in favor of the study group ( P < 0.05). After 12 weeks of intervention, the mean ± SD for numerical pain rating scale and daily Etodolac intake were 4.25 ± 1.9 and 259.25 ± 84.4 mg, in the study group, and 6.22 ± 2.22 and 355.55 ± 93.36 mg in the control group, respectively. The mean difference (95% CI) for numerical pain rating scale and daily Etodolac intake was −1.97 (−3.09: −0.83) and −96.3 (−144.9: −47.69), between groups post treatment, respectively. Conclusion: Adding TENS to physical therapy exercise program is more effective than physical therapy program alone in improving pain in male patients with pudendal neuralgia as measured by numerical pain rating scale and daily analgesic intake dose.

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