Nd-Yag Laser Use in Face-Lift Surgery

1996 ◽  
Vol 13 (3) ◽  
pp. 239-244
Author(s):  
Jung I. Park
Keyword(s):  
Laser Physics ◽  
Blood Vessels ◽  
Tissue Damage ◽  
Clinical Applications ◽  
Social Activities ◽  
Face Lift ◽  
Yag Laser

The use of the Nd-Yag laser with contact tip for face-lift surgery has significantly reduced postoperative ecchymosis. The Nd-Yag laser causes less tissue damage than electrocautery, and has a better ability to coagulate blood vessels than the CO2 laser. This paper describes laser physics and the mechanics of the Nd-Yag laser contact tip and the clinical applications, and shows results of patients who have had the procedure done with the Nd-Yag laser contact tip. There was very little evidence of ecchymosis postoperatively, which enables patients to return to social activities and/or work rapidly.

Reduction Mammaplasty Using Nd:YAG Contact Tip Laser

1993 ◽  
Vol 10 (3) ◽  
pp. 201-206 ◽  
Author(s):  
Jung I. Park
Keyword(s):  
Laser Physics ◽  
Blood Vessels ◽  
Tissue Damage ◽  
Nd:Yag Laser ◽  
Reduction Mammaplasty ◽  
The Other ◽  
Other Hand ◽  
Cold Knife ◽  
Back To Work

Nd:YAG laser with contact tip provides unique advantages over a cold knife and electrocautery in a surgical dissection. The Nd:YAG laser places somewhere in the middle between the traditional electrocautery and the CO2 laser. The Nd:YAG laser has much less tissue damage compared to electrocautery. On the other hand, this laser has afar better ability to coagulate the blood vessels and the advantage of easy maneuverability as compared to the CO2 laser. The author presents his experiences in Nd:YAG laser contact tip for reduction mammaplasty. Seventeen reduction mammaplasties using Nd:YAG contact laser tip were presented. Several patients returned to work within a week after surgery. One patient was well enough to volunteer to go back to work on the fourth post-operative day. The Nd:YAG laser physics, equipment, applications, and surgical cases are discussed.

Office-Based Laser Surgery Oto-Rhino-Laryngology

1995 ◽  
Vol 112 (5) ◽  
pp. P172-P172
Author(s):  
Yosef P. Krespi ◽  
Andrew Blitzer ◽  
Steven J. Pearlman ◽  
Herbert Silverstein
Keyword(s):  
Laser Physics ◽  
Laser Surgery ◽  
Educational Objectives ◽  
Laser Safety ◽  
Yag Laser ◽  
Office Setting

Educational objectives: To learn basic laser physics, office laser safety, and applications of the CO2 and YAG laser in a comprehensive otolaryngology office setting.

scholarly journals Antifungal benzimidazoles disrupt vasculature by targeting one of nine β-tubulins

2020 ◽  
Author(s):  
Riddhiman K. Garge ◽  
Hye Ji Cha ◽  
Chanjae Lee ◽  
Jimmy D. Gollihar ◽  
Aashiq H. Kachroo ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Vascular Endothelial Cells ◽  
Tissue Level ◽  
Clinical Applications ◽  
Vascular Endothelial ◽  
Human Cell Culture ◽  
Vascular Disrupting Agent ◽  
Tubulin Isotypes ◽  
Vascular Disruption ◽  
Resistance Data

ABSTRACTThiabendazole (TBZ) is an FDA-approved benzimidazole widely used for its antifungal and antihelminthic properties. We showed previously that TBZ is also a potent vascular disrupting agent and inhibits angiogenesis at the tissue level by dissociating vascular endothelial cells in newly formed blood vessels. Here, we uncover TBZ’s molecular target and mechanism of action. Using human cell culture, molecular modeling, and humanized yeast, we find that TBZ selectively targets only 1 of 9 human β-tubulin isotypes (TUBB8) to specifically disrupt endothelial cell microtubules. By leveraging epidemiological pesticide resistance data and mining chemical features of commercially used benzimidazoles, we discover that a broader class of benzimidazole compounds, in extensive use for 50 years, also potently disrupt immature blood vessels and inhibit angiogenesis. Thus, besides identifying the molecular mechanism of benzimidazole-mediated vascular disruption, this study presents evidence relevant to the widespread use of these compounds while offering potential new clinical applications.

Rheomacrodex

1964 ◽  
Vol 2 (6) ◽  
pp. 24-24
Keyword(s):  
Molecular Weight ◽  
Blood Vessels ◽  
High Molecular Weight ◽  
Plasma Volume ◽  
Tissue Damage ◽  
Sucrose Solution ◽  
Red Cells ◽  
Lower Molecular Weight ◽  
Low Molecular Weight

Dextrans are chain polymers of glucose of high molecular weight, which are produced when certain bacteria are incubated with sucrose solution. Solutions of dextrans of high or low molecular weight may be extracted. Dextrans of high molecular weight (75,000 – 200,000) are used as plasma volume expanders (e. g. Intradex - Glaxo; Dextraven - Benger), and dextrans of lower molecular weight (40,000) are claimed to be useful in improving flow by preventing any tendency that red cells have to clump and block small blood vessels (Rheomacrodex - Pharmacia). Such clumping of red cells may occur after tissue damage; it is sometimes called sludging of blood.

Effect of Time-Dependent Boundary Conditions on Epidermal Tissue Damage During Port Wine Stain Laser Surgery

2001 ◽  
Author(s):  
Guillermo Aguilar ◽  
Sergio H. Diaz Valdes ◽  
J. Stuart Nelson ◽  
Enrique J. Lavernia
Keyword(s):  
Boundary Conditions ◽  
Blood Vessels ◽  
Laser Therapy ◽  
Tissue Damage ◽  
Laser Surgery ◽  
Thermal Damage ◽  
Laser Light ◽  
Time Dependent ◽  
Port Wine Stain ◽  
Port Wine

Abstract Port wine stain (PWS) birthmarks are a congenital and progressive vascular malformation of the dermis, involving capillaries, which occurs in approximately 0.7% of children. The objective of laser surgery for this and similar conditions is to cause selective thermal damage, thrombosis, and, eventually, permanent photocoagulation in the PWS vessels. To achieve this, the radiated laser light is set at a specific wavelength, which is highly absorbed by the blood vessels’ hemoglobin (the major chromophore in blood). Unfortunately, the PWS vessels do not absorb all energy radiated — a significant amount is also absorbed by hemoglobin in the ectatic capillaries of the upper dermis. This unwanted absorption causes two problems: firstly, insufficient heat generation within the targeted vessels leads to poor clinical results, and, secondly, there is an increased risk of damage to the overlying epidermis. In current PWS laser therapy, cryogen spray cooling (CSC) is used effectively to cool and protect selectively the epidermis (tens of micrometers thick) prior to the laser pulse, while minimally cooling the blood vessels. The thermal response of the system is characterized by time and/or temperature dependent boundary conditions. However, in many recent studies, the boundary conditions induced by CSC are regarded as constant. In the present work we study the effects of time-dependent boundary conditions on the overall epidermal thermal damage after PWS laser therapy. We use computer models to simulate the laser light distribution, heat diffusion, and tissue damage, and introduce experimentally determined time-dependent boundary conditions measured for custom-made and commercial atomizing nozzles. We show that time-dependent boundary conditions have a significant effect in the optimal laser dose required to induce photocoagulation of PWS blood vessels while preserving the epidermis.

Modified Skin Incision and Location of Burr-Hole Surgery via a Retrosigmoid Approach: An Anatomical Study

2022 ◽  
Author(s):  
Lean Sun ◽  
Min Qi ◽  
Xuefei Shao ◽  
Sansong Chen ◽  
Xinyun Fang ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Tissue Damage ◽  
Cerebellopontine Angle ◽  
Anatomical Study ◽  
Skin Incision ◽  
Sigmoid Sinus ◽  
Burr Hole ◽  
Retrosigmoid Approach ◽  
Positioning Method

Abstract Objective This study aims to reduce the tissue damage during craniotomy with retrosigmoid approach. A modified sickle-shaped skin incision was developed, and a new burr-hole positioning method was proposed. Methods Five adult cadaveric heads (10 sides) were used in this study. The sickle-shaped skin incision was performed during craniotomy. The nerves, blood vessels, and muscles were observed and measured under a microscope. Additionally, 62 dry adult skull specimens (left sided, n = 35; right sided, n = 27) were used to measure the distance between the most commonly used locating point (asterion [Ast] point) and the posteroinferior point of the transverse sigmoid sinus junction (PSTS) (Ast-PSTS), as well as the distance between the new locating O point and the PSTS (O-PSTS). Then, the reliability of the new locating O point was validated on the same five adult cadaveric heads (10 sides) used for the sickle-shaped skin incision. Results The sickle-shaped skin incision reduced the damage to the occipital nerves, blood vessels, and muscles during the surgery via a retrosigmoid approach. The dispersion and variability of O-PSTS were smaller than those of Ast-PSTS. Conclusion The sickle-shaped skin incision of the retrosigmoid approach can reduce the tissue damage and can completely expose the structures in the cerebellopontine angle. The modified O point is a more reliable locating point for a burr-hole surgery than the Ast point.

Bed sores

1968 ◽  
Vol 6 (16) ◽  
pp. 61-62
Keyword(s):  
Blood Vessels ◽  
Tissue Damage ◽  
Controlled Trials ◽  
Pressure Sores ◽  
Greater Trochanter ◽  
Prolonged Sitting ◽  
Prevention And Treatment ◽  
Bed Sores ◽  
Poor Nutrition

Bed sores occur in patients immobilised because of age or disease. Sores are due to damage by direct or shearing pressure on the blood vessels in the muscles, fat and skin overlying bony points, especially when there is loss of superficial sensation, poor nutrition or soiling with urine or faeces. Tissue damage can occur within hours. The heels and sacral areas are most susceptible, but contractures and other deformities may predispose to necrosis at other pressure areas such as the elbow or greater trochanter. Pressure sores can also develop through prolonged sitting. Patients with bed sores take up to 50% longer to nurse than they would take without bed sores.1 Controlled trials are difficult to perform, and critical publications on the prevention and treatment of bed sores are few.2–4

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